CN1221547C - 莱因佐里得－ⅱ型晶体 - Google Patents

莱因佐里得－ⅱ型晶体 Download PDF

Info

Publication number
CN1221547C
CN1221547C CNB018034489A CN01803448A CN1221547C CN 1221547 C CN1221547 C CN 1221547C CN B018034489 A CNB018034489 A CN B018034489A CN 01803448 A CN01803448 A CN 01803448A CN 1221547 C CN1221547 C CN 1221547C
Authority
CN
China
Prior art keywords
solvent
methyl
phenyl
ethanamide
oxazolidinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB018034489A
Other languages
English (en)
Chinese (zh)
Other versions
CN1394207A (zh
Inventor
M·S·伯格伦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22658183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1221547(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia and Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of CN1394207A publication Critical patent/CN1394207A/zh
Application granted granted Critical
Publication of CN1221547C publication Critical patent/CN1221547C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNB018034489A 2000-02-02 2001-01-29 莱因佐里得－ⅱ型晶体 Expired - Fee Related CN1221547C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17983700P 2000-02-02 2000-02-02
US60/179,837 2000-02-02

Publications (2)

Publication Number Publication Date
CN1394207A CN1394207A (zh) 2003-01-29
CN1221547C true CN1221547C (zh) 2005-10-05

Family

ID=22658183

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018034489A Expired - Fee Related CN1221547C (zh) 2000-02-02 2001-01-29 莱因佐里得－ⅱ型晶体

Country Status (30)

Country Link
EP (1) EP1255754B1 (https=)
JP (1) JP5235256B2 (https=)
KR (3) KR100864745B1 (https=)
CN (1) CN1221547C (https=)
AR (1) AR027261A1 (https=)
AT (1) ATE297920T1 (https=)
AU (1) AU782138B2 (https=)
BR (1) BR0107667A (https=)
CA (1) CA2395603C (https=)
CO (1) CO5261555A1 (https=)
CZ (1) CZ302292B6 (https=)
DE (1) DE60111497T2 (https=)
DK (1) DK1255754T3 (https=)
EA (1) EA004434B1 (https=)
EE (1) EE05197B1 (https=)
ES (1) ES2242728T3 (https=)
HU (1) HUP0301076A3 (https=)
IL (1) IL151010A0 (https=)
MX (1) MXPA02007471A (https=)
MY (1) MY122829A (https=)
NO (2) NO323459B1 (https=)
NZ (1) NZ520541A (https=)
PE (1) PE20011086A1 (https=)
PL (1) PL356433A1 (https=)
PT (1) PT1255754E (https=)
SI (1) SI1255754T1 (https=)
SK (1) SK287025B6 (https=)
TW (1) TWI297687B (https=)
WO (1) WO2001057035A1 (https=)
ZA (1) ZA200205162B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102731341A (zh) * 2011-04-13 2012-10-17 上海医药工业研究院 用于制备利奈唑胺的中间体及其制备方法

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100490643B1 (ko) * 2002-10-29 2005-05-19 한국과학기술연구원 새로운 메틸리덴 피페리딘일 옥사졸리딘온 유도체 및이들의 제조방법
PT1673370E (pt) 2003-10-16 2009-11-05 Symed Labs Ltd Forma cristalina de linezolida
WO2005099353A2 (en) 2004-04-19 2005-10-27 Symed Labs Limited A novel process for the preparation of linezolid and related compounds
CA2572207A1 (en) * 2004-06-29 2006-10-19 Teva Pharmaceutical Industries Ltd. Solid forms of linezolid and processes for preparation thereof
US20060142283A1 (en) * 2004-06-29 2006-06-29 Judith Aronhime Crystalline form IV of linezolid
WO2006091731A2 (en) * 2005-02-24 2006-08-31 Teva Pharmaceutical Industries Ltd. Processes for the preparation of linezolid intermediate
MX2007002113A (es) * 2005-06-22 2007-04-27 Teva Pharma Formas polimorfas de maleato de tegaserod.
AU2006277017A1 (en) * 2005-07-20 2007-02-15 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical composition comprising linezolid form IV
WO2007102082A1 (en) * 2006-03-09 2007-09-13 Glenmark Pharmaceuticals Limited High oxazolidinone content solid dosage forms
EP2099299A4 (en) * 2006-10-23 2011-11-30 Concert Pharmaceuticals Inc OXAZOLIDINONE DERIVATIVES AND METHOD FOR THEIR USE
WO2011050826A1 (en) 2009-10-28 2011-05-05 Synthon B.V. Process for making crystalline form a of linezolid
MX2012012627A (es) 2010-04-30 2013-05-09 Univ Indiana Res & Tech Corp Proceso para preparar linezolid.
EP2603505A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
EP2603506A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
WO2012114354A1 (en) * 2011-02-24 2012-08-30 Lee Pharma Limited Anhydrous linezolid crystalline form-ii
EP2683696A1 (en) 2011-03-09 2014-01-15 Synthon BV Process for making crystalline form a of linezolid
CN102766106A (zh) * 2011-05-03 2012-11-07 江苏豪森医药集团有限公司 利奈唑胺的新晶型及其制备方法
CN102399200B (zh) * 2011-12-14 2013-12-04 浙江新东港药业股份有限公司 一种利用悬浮结晶法制备利奈唑胺晶型ⅰ的方法
IN2014DN06213A (https=) 2012-01-24 2015-10-23 Jubilant Life Sciences Ltd
WO2013120496A1 (en) 2012-02-14 2013-08-22 Pharmathen S.A. Process for the preparation of linezolid in crystalline form and salts thereof
CN102643245A (zh) * 2012-04-10 2012-08-22 杭州华东医药集团生物工程研究所有限公司 一种利奈唑胺晶型及其制备方法
EP2917189B1 (en) 2012-11-09 2016-08-17 Synthon BV Process for making linezolid
DK3541442T3 (da) 2016-11-16 2022-03-14 Persica Pharmaceuticals Ltd Antibiotiske formuleringer mod lændesmerter
DK3709970T3 (da) * 2017-11-16 2025-07-07 Persica Pharmaceuticals Ltd Linezolidformuleringer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
DK1114819T3 (da) * 1996-04-11 2008-04-14 Pharmacia & Upjohn Co Llc Fremgangsmåde til fremstilling af oxazolidinoner
EP1772453A1 (en) * 1997-11-07 2007-04-11 Pharmacia & Upjohn Company LLC Process to produce Oxazolidinones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102731341A (zh) * 2011-04-13 2012-10-17 上海医药工业研究院 用于制备利奈唑胺的中间体及其制备方法

Also Published As

Publication number Publication date
PT1255754E (pt) 2005-11-30
KR20080044358A (ko) 2008-05-20
MY122829A (en) 2006-05-31
EP1255754B1 (en) 2005-06-15
AR027261A1 (es) 2003-03-19
CN1394207A (zh) 2003-01-29
JP5235256B2 (ja) 2013-07-10
CZ20022635A3 (cs) 2002-10-16
EA004434B1 (ru) 2004-04-29
SK9942002A3 (en) 2002-11-06
PL356433A1 (en) 2004-06-28
AU3275501A (en) 2001-08-14
EE05197B1 (et) 2009-08-17
NO20065836L (no) 2002-08-01
WO2001057035A1 (en) 2001-08-09
SK287025B6 (sk) 2009-10-07
DE60111497D1 (de) 2005-07-21
HUP0301076A2 (hu) 2003-08-28
HUP0301076A3 (en) 2004-06-28
CZ302292B6 (cs) 2011-02-09
IL151010A0 (en) 2003-02-12
AU782138B2 (en) 2005-07-07
SI1255754T1 (sl) 2005-12-31
KR20070087178A (ko) 2007-08-27
HK1051196A1 (en) 2003-07-25
ATE297920T1 (de) 2005-07-15
NZ520541A (en) 2004-02-27
NO20023654L (no) 2002-08-01
CO5261555A1 (es) 2003-03-31
KR20020072300A (ko) 2002-09-14
DK1255754T3 (da) 2005-08-22
JP2003522175A (ja) 2003-07-22
ZA200205162B (en) 2003-09-29
PE20011086A1 (es) 2001-10-04
CA2395603A1 (en) 2001-08-09
NO20023654D0 (no) 2002-08-01
TWI297687B (en) 2008-06-11
EE200200420A (et) 2003-12-15
KR100781815B1 (ko) 2007-12-03
BR0107667A (pt) 2002-10-08
NO323459B1 (no) 2007-05-14
KR100864745B1 (ko) 2008-10-22
CA2395603C (en) 2010-03-23
DE60111497T2 (de) 2006-05-18
EP1255754A1 (en) 2002-11-13
EA200200819A1 (ru) 2003-02-27
MXPA02007471A (es) 2002-12-13
ES2242728T3 (es) 2005-11-16

Similar Documents

Publication Publication Date Title
CN1221547C (zh) 莱因佐里得－ⅱ型晶体
US6444813B2 (en) Linezolid-crystal form II
US7718800B2 (en) Crystalline form of linezolid
CN1324351A (zh) 制备西酞普兰的方法
CN1496345A (zh) 链状低聚乳酸酯
CN1379771A (zh) 环状乳酸齐聚物的制备方法
HK1051196B (en) Linezolid-crystal form ii
CN1258675A (zh) 制备5－脂肪氧合酶抑制剂的方法和中间体
CN1185235C (zh) 双(氟代芳基)硼衍生物的制备方法
CN1025620C (zh) 1-碳代(去硫杂)头孢菌素的制备方法
CN1215052A (zh) 药理活性的对映体及其制备方法
HK1065997A1 (en) Method for the preparation of citalopram
HK1065997B (en) Method for the preparation of citalopram
HK1030940B (en) Method for the preparation of citalopram
HK1030940A1 (en) Method for the preparation of citalopram
CN1528739A (zh) 一种左旋多巴甲酯盐酸盐的纯化方法
CN1081668A (zh) (1′r,3s,4r)4-酰硫基氮杂环丁酮

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20051005

Termination date: 20120129