CN1216869C - 赛利可喜的多态晶型 - Google Patents
赛利可喜的多态晶型 Download PDFInfo
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- CN1216869C CN1216869C CN008060835A CN00806083A CN1216869C CN 1216869 C CN1216869 C CN 1216869C CN 008060835 A CN008060835 A CN 008060835A CN 00806083 A CN00806083 A CN 00806083A CN 1216869 C CN1216869 C CN 1216869C
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
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- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
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US16985699P | 1999-12-08 | 1999-12-08 | |
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US60/169856 | 1999-12-08 |
Publications (2)
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CN1411447A CN1411447A (zh) | 2003-04-16 |
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CN (1) | CN1216869C (es) |
AR (2) | AR027897A1 (es) |
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BG (1) | BG65239B1 (es) |
CO (1) | CO5251445A1 (es) |
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EA (1) | EA200401397A1 (es) |
EC (1) | ECSP003807A (es) |
ES (1) | ES2236011T3 (es) |
HU (1) | HUP0200580A3 (es) |
MY (2) | MY128971A (es) |
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OA (1) | OA11831A (es) |
PE (1) | PE20010911A1 (es) |
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WO (1) | WO2001041536A2 (es) |
YU (1) | YU57801A (es) |
ZA (2) | ZA200107146B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
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ES2290157T3 (es) * | 2000-07-20 | 2008-02-16 | Lauras As | Uso de inhibidores de cox-2 como inmunoestimulantes en el tratamiento de vih o sida. |
DE60233874D1 (de) | 2001-06-22 | 2009-11-12 | Pfizer Prod Inc | Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren |
US7790905B2 (en) | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
WO2004061433A1 (en) * | 2002-12-30 | 2004-07-22 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions with improved dissolution |
US7446107B2 (en) | 2002-02-15 | 2008-11-04 | Transform Pharmaceuticals, Inc. | Crystalline forms of conazoles and methods of making and using the same |
JP4906233B2 (ja) | 2002-03-01 | 2012-03-28 | ユニバーシティー オブ サウス フロリダ | 少なくとも1種の有効薬剤成分を含有する多構成要素固相 |
AU2003299482A1 (en) * | 2002-05-13 | 2004-06-07 | Pharmacia Corporation | Stable amorphous celecoxib composite and process therefor |
AU2003243354A1 (en) | 2002-05-31 | 2003-12-19 | Transform Pharmaceuticals, Inc. | Novel conazole crystalline forms and related processes, pharmaceutical compositions and methods |
MXPA05000232A (es) * | 2002-06-21 | 2005-06-17 | Transform Pharmaceuticals Inc | Composiciones farmaceuticas con disolucion mejorada. |
US20060052432A1 (en) * | 2002-09-20 | 2006-03-09 | Julius Remenar | Pharmaceutical compositions with improved dissolution |
EP1579198A1 (en) * | 2002-12-30 | 2005-09-28 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions with improved dissolution |
US8183290B2 (en) | 2002-12-30 | 2012-05-22 | Mcneil-Ppc, Inc. | Pharmaceutically acceptable propylene glycol solvate of naproxen |
WO2006000228A2 (en) * | 2004-06-29 | 2006-01-05 | Nycomed Danmark Aps | Manufacturing of quick release pharmaceutical compositions of water insoluble drugs and pharmaceutical compositions obtained by the process of the invention |
GB0423103D0 (en) * | 2004-10-19 | 2004-11-17 | Boots Healthcare Int Ltd | Therapeutic agents |
WO2006097459A1 (en) * | 2005-03-14 | 2006-09-21 | Nycomed Gmbh | Method for preventing cardiovascular diseases |
CN103462920A (zh) * | 2012-06-06 | 2013-12-25 | 南京亿华药业有限公司 | 一种口服环加氧酶-2抑制剂塞来昔布的组合物 |
CN103524416B (zh) * | 2013-10-29 | 2016-08-17 | 湖北华世通生物医药科技有限公司 | 一种塞来昔布新晶型a及其制备方法 |
CN103539739B (zh) * | 2013-10-30 | 2016-02-10 | 中美华世通生物医药科技(武汉)有限公司 | 一种塞来昔布新晶型b及其制备方法 |
CN103508958A (zh) * | 2013-10-30 | 2014-01-15 | 中美华世通生物医药科技(武汉)有限公司 | 一种塞来昔布新晶型c及其制备方法 |
KR101476096B1 (ko) * | 2014-03-28 | 2014-12-24 | 대원제약주식회사 | 용해도가 향상된 쎄레콕시브의 약제학적 조성물 |
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Publication number | Priority date | Publication date | Assignee | Title |
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US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
KR100229343B1 (ko) * | 1993-11-30 | 1999-11-01 | 윌리암스 로저 에이 | 염증치료용 치환 피라졸일벤젠술폰아미드 |
US5633272A (en) * | 1995-02-13 | 1997-05-27 | Talley; John J. | Substituted isoxazoles for the treatment of inflammation |
AU699593B2 (en) * | 1995-02-13 | 1998-12-10 | G.D. Searle & Co. | Substituted isoxazoles for the treatment of inflammation |
US5756529A (en) * | 1995-09-29 | 1998-05-26 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies |
US5981576A (en) * | 1995-10-13 | 1999-11-09 | Merck Frosst Canada, Inc. | (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors |
EP0863134A1 (en) * | 1997-03-07 | 1998-09-09 | Merck Frosst Canada Inc. | 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2 |
US20070004655A9 (en) * | 1998-04-27 | 2007-01-04 | Murphy Gerald P | Nr-cam gene, nucleic acids and nucleic acid products for therapeutic and diagnostic uses for tumors |
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EA200401397A1 (ru) | 2005-08-25 |
TWI276435B (en) | 2007-03-21 |
NZ529933A (en) | 2005-06-24 |
OA11831A (en) | 2005-08-23 |
ZA200107149B (en) | 2003-02-28 |
CO5251445A1 (es) | 2003-02-28 |
KR20020002386A (ko) | 2002-01-09 |
ES2236011T3 (es) | 2005-07-16 |
HUP0200580A2 (hu) | 2002-11-28 |
MY128366A (en) | 2007-01-31 |
PE20010911A1 (es) | 2001-09-10 |
KR100717570B1 (ko) | 2007-05-15 |
SV2002000235A (es) | 2002-06-13 |
BG105808A (en) | 2002-09-30 |
CN1411447A (zh) | 2003-04-16 |
BG65239B1 (bg) | 2007-09-28 |
PT1150959E (pt) | 2008-04-21 |
AU2041201A (en) | 2001-06-18 |
WO2001041536A2 (en) | 2001-06-14 |
ECSP003807A (es) | 2005-07-06 |
AR030039A1 (es) | 2003-08-13 |
PT1150960E (pt) | 2005-06-30 |
ZA200107146B (en) | 2002-08-29 |
MY128971A (en) | 2007-03-30 |
CZ20012875A3 (cs) | 2002-02-13 |
YU57801A (sh) | 2005-07-19 |
HUP0200580A3 (en) | 2002-12-28 |
AR027897A1 (es) | 2003-04-16 |
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