MY128366A - Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect - Google Patents

Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect

Info

Publication number
MY128366A
MY128366A MYPI20005733A MYPI20005733A MY128366A MY 128366 A MY128366 A MY 128366A MY PI20005733 A MYPI20005733 A MY PI20005733A MY PI20005733 A MYPI20005733 A MY PI20005733A MY 128366 A MY128366 A MY 128366A
Authority
MY
Malaysia
Prior art keywords
cyclooxygenase
therapeutic effect
rapid onset
inhibitor compositions
compositions
Prior art date
Application number
MYPI20005733A
Inventor
Tugrul T Kararli
Mark J Kontny
Subbash Desai
Michael J Hageman
Royal J Haskell
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of MY128366A publication Critical patent/MY128366A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract

PHARMACEUTICAL COMPOSITIONS ARE PROVIDED COMPRISING ONE OR MORE ORALLY DELIVERABLE DOSE UNITS, EACH COMPRISING A SELECTIVE CYCLOOXYGENASE-2 INHIBITORY DRUG OF LOW WATER SOLUBILITY IN A THERAPEUTICALLY EFFECTIVE AMOUNT, WHEREIN THE DRUG IS PRESENT IN THE FORM OF SOLID PARTICLES, ABOUT 25TO 100BY WEIGHT OF WHICH ARE SMALLER THAN 1 µM. THE COMPOSITIONS ARE USEFUL IN TREATMENT OF PROPHYLAXIS OF CYCLOOXYGENASE-2 MEDIATED CONDITIONS AND DISORDERS AND HAVE PARTICULAR ADVANTAGES WHERE RAPID ONSET OF THERAPEUTIC EFFECT IS DESIRED.
MYPI20005733A 1999-12-08 2000-12-06 Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect MY128366A (en)

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MYPI20005730A MY128971A (en) 1999-12-08 2000-12-06 Solid-state form of celecoxib having enhanced bioavailability
MYPI20005733A MY128366A (en) 1999-12-08 2000-12-06 Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect

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MYPI20005730A MY128971A (en) 1999-12-08 2000-12-06 Solid-state form of celecoxib having enhanced bioavailability

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KR (1) KR100717570B1 (en)
CN (1) CN1216869C (en)
AR (2) AR027897A1 (en)
AU (1) AU2041201A (en)
BG (1) BG65239B1 (en)
CO (1) CO5251445A1 (en)
CZ (1) CZ20012875A3 (en)
EA (1) EA200401397A1 (en)
EC (1) ECSP003807A (en)
ES (1) ES2236011T3 (en)
HU (1) HUP0200580A3 (en)
MY (2) MY128971A (en)
NZ (1) NZ529933A (en)
OA (1) OA11831A (en)
PE (1) PE20010911A1 (en)
PT (2) PT1150960E (en)
SV (1) SV2002000235A (en)
TW (1) TWI276435B (en)
WO (1) WO2001041536A2 (en)
YU (1) YU57801A (en)
ZA (2) ZA200107146B (en)

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AU2003303591A1 (en) * 2002-12-30 2004-07-29 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
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ES2450648T3 (en) * 2004-06-29 2014-03-25 Takeda Pharma A/S Manufacture of pharmaceutical compositions with rapid release of water insoluble drugs and pharmaceutical compositions obtained by the process of the invention
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CN103462920A (en) * 2012-06-06 2013-12-25 南京亿华药业有限公司 Oral cyclo-oxygenase-2 inhibitor Celecoxib composition
CN103524416B (en) * 2013-10-29 2016-08-17 湖北华世通生物医药科技有限公司 A kind of Novel celecoxib crystal form A and preparation method thereof
CN103508958A (en) * 2013-10-30 2014-01-15 中美华世通生物医药科技（武汉）有限公司 Novel celecoxib crystal form C and preparation method thereof
CN103539739B (en) * 2013-10-30 2016-02-10 中美华世通生物医药科技（武汉）有限公司 A kind of Novel celecoxib crystal form B and preparation method thereof
KR101476096B1 (en) * 2014-03-28 2014-12-24 대원제약주식회사 Pharmaceutical composition comprising celecoxib with improved solubility

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CN1216869C (en) 2005-08-31
TWI276435B (en) 2007-03-21
PT1150960E (en) 2005-06-30
ZA200107149B (en) 2003-02-28
AU2041201A (en) 2001-06-18
CO5251445A1 (en) 2003-02-28
WO2001041536A2 (en) 2001-06-14
ZA200107146B (en) 2002-08-29
OA11831A (en) 2005-08-23
KR20020002386A (en) 2002-01-09
AR030039A1 (en) 2003-08-13
BG105808A (en) 2002-09-30
NZ529933A (en) 2005-06-24
HUP0200580A2 (en) 2002-11-28
KR100717570B1 (en) 2007-05-15
AR027897A1 (en) 2003-04-16
CN1411447A (en) 2003-04-16
PE20010911A1 (en) 2001-09-10
YU57801A (en) 2005-07-19
CZ20012875A3 (en) 2002-02-13
SV2002000235A (en) 2002-06-13
EA200401397A1 (en) 2005-08-25
BG65239B1 (en) 2007-09-28
ECSP003807A (en) 2005-07-06
MY128971A (en) 2007-03-30
PT1150959E (en) 2008-04-21
ES2236011T3 (en) 2005-07-16
HUP0200580A3 (en) 2002-12-28

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