CN1167759A - 取代的2-萘甲酰胍、其制备方法、用途及含有它们的药物 - Google Patents
取代的2-萘甲酰胍、其制备方法、用途及含有它们的药物 Download PDFInfo
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- CN1167759A CN1167759A CN97113187A CN97113187A CN1167759A CN 1167759 A CN1167759 A CN 1167759A CN 97113187 A CN97113187 A CN 97113187A CN 97113187 A CN97113187 A CN 97113187A CN 1167759 A CN1167759 A CN 1167759A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19621483.1 | 1996-05-29 | ||
| DE19621483A DE19621483A1 (de) | 1996-05-29 | 1996-05-29 | Substituierte 2-Naphthoylguanidine, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1167759A true CN1167759A (zh) | 1997-12-17 |
Family
ID=7795549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97113187A Pending CN1167759A (zh) | 1996-05-29 | 1997-05-27 | 取代的2-萘甲酰胍、其制备方法、用途及含有它们的药物 |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6087304A (enExample) |
| EP (1) | EP0810206B1 (enExample) |
| JP (1) | JP4039588B2 (enExample) |
| KR (1) | KR970074776A (enExample) |
| CN (1) | CN1167759A (enExample) |
| AR (1) | AR008373A1 (enExample) |
| AT (1) | ATE198320T1 (enExample) |
| AU (1) | AU710065B2 (enExample) |
| BR (1) | BR9703338A (enExample) |
| CA (1) | CA2206366C (enExample) |
| CZ (1) | CZ163097A3 (enExample) |
| DE (2) | DE19621483A1 (enExample) |
| DK (1) | DK0810206T3 (enExample) |
| ES (1) | ES2154002T3 (enExample) |
| GR (1) | GR3035126T3 (enExample) |
| HR (1) | HRP970292B1 (enExample) |
| HU (1) | HUP9700955A3 (enExample) |
| ID (1) | ID16989A (enExample) |
| IL (1) | IL120924A (enExample) |
| NO (1) | NO308527B1 (enExample) |
| NZ (1) | NZ314915A (enExample) |
| PL (1) | PL185754B1 (enExample) |
| PT (1) | PT810206E (enExample) |
| RU (1) | RU2190600C2 (enExample) |
| SI (1) | SI0810206T1 (enExample) |
| SK (1) | SK282020B6 (enExample) |
| TR (1) | TR199700428A2 (enExample) |
| TW (1) | TW416944B (enExample) |
| ZA (1) | ZA974665B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102482220A (zh) * | 2009-08-06 | 2012-05-30 | 安斯泰来制药有限公司 | 含氮环酰基胍衍生物 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19621482A1 (de) | 1996-05-29 | 1997-12-04 | Hoechst Ag | Substituierte 1-Naphthoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| EP1159273A1 (en) | 1999-03-02 | 2001-12-05 | Boehringer Ingelheim Pharmaceuticals Inc. | Compounds useful as reversible inhibitors of cathepsin s |
| US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
| AR039156A1 (es) * | 2002-03-28 | 2005-02-09 | Novartis Ag | Amidas del acido piperidinilamino sulfamico o piperazinil sulfamico y su uso para la manufactura de un medicamento en enfermedades mediadas por la accion de la sulfatasa esteroide |
| DK1755593T3 (da) * | 2004-06-02 | 2008-05-19 | Hoffmann La Roche | Naphtalenderivater der er nyttige som histamin-3-receptorligander |
| TW200614995A (en) * | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors |
| AU2013205388B2 (en) * | 2005-06-24 | 2016-05-05 | Biotron Limited | Antiviral compounds and methods |
| EP2826770B1 (en) | 2005-06-24 | 2018-09-12 | Biotron Limited | Acylguanidine compounds with antiviral activity |
| DE602007008742D1 (de) * | 2006-09-15 | 2010-10-07 | Pfizer | Substituierte pyridylmethylbicyclocarboxyamidverbindungen |
| EP2394987A4 (en) * | 2009-02-09 | 2012-09-05 | Astellas Pharma Inc | ACYLGUANIDINDERIVAT |
| US20120041036A1 (en) * | 2009-02-09 | 2012-02-16 | Isao Kinoyama | Substituted acylguanidine derivatives (as amended) |
| EP2671869B1 (en) | 2011-02-02 | 2015-11-04 | Astellas Pharma Inc. | Tetrahydroisoquinoline derivative |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4251545A (en) * | 1979-09-19 | 1981-02-17 | Gaf Corporation | Fungicidal process using 1-(alkoxyaroyl)guanidines |
| IT1238227B (it) * | 1989-12-01 | 1993-07-12 | Modulo di smistamento per impianti di convogliamento a nastro e simili | |
| DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| IL109570A0 (en) * | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4318658A1 (de) * | 1993-06-04 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4415873A1 (de) * | 1994-05-05 | 1995-11-09 | Hoechst Ag | Substituierte bizyklische Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| JPH08225513A (ja) * | 1994-12-21 | 1996-09-03 | Kanebo Ltd | ナフトイルグアニジン誘導体 |
| DE19621482A1 (de) * | 1996-05-29 | 1997-12-04 | Hoechst Ag | Substituierte 1-Naphthoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-05-29 DE DE19621483A patent/DE19621483A1/de not_active Withdrawn
-
1997
- 1997-02-28 PL PL97318723A patent/PL185754B1/pl not_active IP Right Cessation
- 1997-05-16 DK DK97108013T patent/DK0810206T3/da active
- 1997-05-16 PT PT97108013T patent/PT810206E/pt unknown
- 1997-05-16 AT AT97108013T patent/ATE198320T1/de not_active IP Right Cessation
- 1997-05-16 US US08/857,631 patent/US6087304A/en not_active Expired - Lifetime
- 1997-05-16 ES ES97108013T patent/ES2154002T3/es not_active Expired - Lifetime
- 1997-05-16 DE DE59702802T patent/DE59702802D1/de not_active Expired - Lifetime
- 1997-05-16 SI SI9730102T patent/SI0810206T1/xx unknown
- 1997-05-16 EP EP97108013A patent/EP0810206B1/de not_active Expired - Lifetime
- 1997-05-27 TW TW086107120A patent/TW416944B/zh not_active IP Right Cessation
- 1997-05-27 CN CN97113187A patent/CN1167759A/zh active Pending
- 1997-05-27 TR TR97/00428A patent/TR199700428A2/xx unknown
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- 1997-05-27 IL IL12092497A patent/IL120924A/en not_active IP Right Cessation
- 1997-05-27 SK SK670-97A patent/SK282020B6/sk unknown
- 1997-05-27 CZ CZ971630A patent/CZ163097A3/cs unknown
- 1997-05-27 HU HU9700955A patent/HUP9700955A3/hu unknown
- 1997-05-27 AU AU23645/97A patent/AU710065B2/en not_active Ceased
- 1997-05-27 AR ARP970102253A patent/AR008373A1/es unknown
- 1997-05-27 NZ NZ314915A patent/NZ314915A/en unknown
- 1997-05-28 NO NO972433A patent/NO308527B1/no not_active IP Right Cessation
- 1997-05-28 ZA ZA9704665A patent/ZA974665B/xx unknown
- 1997-05-28 ID IDP971814A patent/ID16989A/id unknown
- 1997-05-28 RU RU97109003/04A patent/RU2190600C2/ru not_active IP Right Cessation
- 1997-05-28 JP JP13822797A patent/JP4039588B2/ja not_active Expired - Fee Related
- 1997-05-28 KR KR1019970021107A patent/KR970074776A/ko not_active Ceased
- 1997-05-28 CA CA002206366A patent/CA2206366C/en not_active Expired - Fee Related
- 1997-05-30 BR BR9703338A patent/BR9703338A/pt not_active IP Right Cessation
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102482220A (zh) * | 2009-08-06 | 2012-05-30 | 安斯泰来制药有限公司 | 含氮环酰基胍衍生物 |
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