CN1155598C - 四氢吡啶醚化合物 - Google Patents
四氢吡啶醚化合物 Download PDFInfo
- Publication number
- CN1155598C CN1155598C CNB998112992A CN99811299A CN1155598C CN 1155598 C CN1155598 C CN 1155598C CN B998112992 A CNB998112992 A CN B998112992A CN 99811299 A CN99811299 A CN 99811299A CN 1155598 C CN1155598 C CN 1155598C
- Authority
- CN
- China
- Prior art keywords
- och
- hydrogen
- compound
- acid
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843504.5 | 1998-09-23 | ||
| DE19843504 | 1998-09-23 | ||
| EP98117988 | 1998-09-23 | ||
| EP98117988.0 | 1998-09-23 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100384351A Division CN100506821C (zh) | 1998-09-23 | 1999-09-17 | 四氢吡啶醚化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1319101A CN1319101A (zh) | 2001-10-24 |
| CN1155598C true CN1155598C (zh) | 2004-06-30 |
Family
ID=26049024
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB998112992A Expired - Fee Related CN1155598C (zh) | 1998-09-23 | 1999-09-17 | 四氢吡啶醚化合物 |
| CNB2004100384351A Expired - Fee Related CN100506821C (zh) | 1998-09-23 | 1999-09-17 | 四氢吡啶醚化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100384351A Expired - Fee Related CN100506821C (zh) | 1998-09-23 | 1999-09-17 | 四氢吡啶醚化合物 |
Country Status (31)
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ292335B6 (cs) | 1998-09-23 | 2003-09-17 | Altana Pharma Ag | Tetrahydropyridoethery, jejich použití a farmaceutický prostředek |
| US6503923B1 (en) | 1999-04-17 | 2003-01-07 | Altana Pharma Ag | Haloalkoxy imidazonaphthyridines |
| CA2285516C (en) * | 1999-05-12 | 2010-12-07 | President And Fellows Of Harvard College | Dopamine transporter imaging agents |
| MXPA02009549A (es) * | 2000-03-29 | 2004-05-14 | Altana Pharma Ag | Imidazopiridinas triciclicas. |
| ATE311389T1 (de) * | 2000-03-29 | 2005-12-15 | Altana Pharma Ag | Wirkstoffvorläufer von imidazopyridin-derivaten |
| CN1692113A (zh) * | 2000-10-25 | 2005-11-02 | 奥坦纳医药公司 | 作为胃分泌抑制剂的多取代咪唑并吡啶 |
| UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| WO2002069968A1 (en) * | 2001-03-08 | 2002-09-12 | Astrazeneca Ab | New use |
| EP1414821B1 (en) | 2001-08-02 | 2006-08-16 | ALTANA Pharma AG | Tricyclic epoxides |
| CN1656096A (zh) * | 2001-08-03 | 2005-08-17 | 奥坦纳医药公司 | 用于治疗胃肠病症的烷基－取代的咪唑吡啶 |
| WO2003014120A1 (en) * | 2001-08-03 | 2003-02-20 | Altana Pharma Ag | Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases |
| EP1476445A1 (en) | 2002-02-15 | 2004-11-17 | ALTANA Pharma AG | Tricyclic n-acyl compounds |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| AU2003227710A1 (en) * | 2002-05-07 | 2003-11-11 | Altana Pharma Ag | New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders |
| MXPA05005117A (es) | 2002-11-19 | 2005-07-01 | Altana Pharma Ag | Imidazopiridinas 8-sustituidas. |
| US7879833B2 (en) | 2002-12-12 | 2011-02-01 | Nycomed Gmbh | Combination medicament |
| KR20050088176A (ko) * | 2002-12-20 | 2005-09-02 | 알타나 파마 아게 | 8-트리알킬실록시-2-메틸-9-페닐-7-옥소-7,8,9,10-테트라히드로이미다조[1,2-ｈ][1,7]나프티리딘 |
| EP1599175A2 (en) * | 2003-02-17 | 2005-11-30 | ALTANA Pharma AG | Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders |
| MXPA04008070A (es) | 2003-03-10 | 2004-11-26 | Altana Pharma Ag | Novedoso proceso para la preparacion de roflumilasto. |
| TW200503783A (en) * | 2003-04-11 | 2005-02-01 | Altana Pharma Ag | Oral pharmaceutical preparation for proton pump antagonists |
| SA04250092B1 (ar) * | 2003-05-14 | 2008-05-04 | التانا فاروا ايه جي | مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً |
| WO2004105795A1 (en) * | 2003-05-27 | 2004-12-09 | Altana Pharma Ag | Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility |
| AU2004268641A1 (en) * | 2003-08-29 | 2005-03-10 | Dynogen Pharmaceuticals, Inc. | Compositions useful for treating gastrointestinal motility disorders |
| ES2452691T5 (es) | 2003-09-16 | 2022-09-14 | Covis Pharma Gmbh | Uso de ciclesonida para el tratamiento de enfermedades respiratorias |
| EP1974730A1 (en) | 2003-11-03 | 2008-10-01 | AstraZeneca AB | Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux |
| AU2004298453A1 (en) | 2003-12-19 | 2005-06-30 | Altana Pharma Ag | Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives |
| NZ549011A (en) * | 2004-02-17 | 2009-04-30 | Altana Pharma Ag | Tricyclic imidazopyridines and intermediates for the synthesis thereof |
| PL1784404T3 (pl) | 2004-09-03 | 2012-04-30 | Yuhan Corp | Pochodne pirolo[2,3-c]pirydyny i sposoby ich wytwarzania |
| EP1784403B1 (en) | 2004-09-03 | 2013-07-17 | Yuhan Corporation | Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof |
| US8148529B2 (en) | 2004-09-03 | 2012-04-03 | Yuhan Corporation | Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof |
| JP5383183B2 (ja) * | 2005-03-16 | 2014-01-08 | タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロフルミラストを含有する矯味された剤形 |
| EP2080513A1 (en) | 2008-01-16 | 2009-07-22 | Schraermeyer, Ulrich, Prof. Dr. rer. nat | Tetrahydropyridoethers for treatment of AMD |
| WO2011004882A1 (ja) * | 2009-07-09 | 2011-01-13 | ラクオリア創薬株式会社 | 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤 |
| WO2012027240A1 (en) * | 2010-08-23 | 2012-03-01 | Schering Corporation | Fused tricyclic inhibitors of mammalian target of rapamycin |
| KR101699145B1 (ko) * | 2012-06-15 | 2017-02-03 | (주)바이오팜솔루션즈 | 페닐알킬설파메이트 화합물 및 이를 포함하는 근육 이완제 조성물 |
| EP3054949A1 (en) | 2013-10-08 | 2016-08-17 | Katairo GmbH | Tetrahydropyridoethers for the treatment of stargardt's disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4468400A (en) * | 1982-12-20 | 1984-08-28 | Schering Corporation | Antiulcer tricyclic imidazo [1,2-a]pyridines |
| DE3855692D1 (de) | 1987-07-16 | 1997-01-16 | Byk Gulden Lomberg Chem Fab | Imidazo[1,2-a]pyridine |
| SE9401197D0 (sv) * | 1994-04-11 | 1994-04-11 | Astra Ab | Active compounds |
| AU702166B2 (en) * | 1994-07-28 | 1999-02-18 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Acylimidazopyridines |
| WO1998042707A1 (en) * | 1997-03-24 | 1998-10-01 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrahydropyrido compounds |
| CU23088A3 (es) * | 1997-03-24 | 2005-10-19 | Altana Pharma Ag | Compuestos de tetra-hidropiridina. |
| CZ292335B6 (cs) | 1998-09-23 | 2003-09-17 | Altana Pharma Ag | Tetrahydropyridoethery, jejich použití a farmaceutický prostředek |
-
1999
- 1999-09-17 CZ CZ20011082A patent/CZ292335B6/cs not_active IP Right Cessation
- 1999-09-17 DK DK99948776T patent/DK1115725T3/da active
- 1999-09-17 ES ES99948776T patent/ES2191464T3/es not_active Expired - Lifetime
- 1999-09-17 HU HU0102990A patent/HUP0102990A3/hu unknown
- 1999-09-17 PL PL99346617A patent/PL193616B1/pl not_active IP Right Cessation
- 1999-09-17 DE DE69905178T patent/DE69905178T2/de not_active Expired - Lifetime
- 1999-09-17 CN CNB998112992A patent/CN1155598C/zh not_active Expired - Fee Related
- 1999-09-17 KR KR1020017003553A patent/KR100668400B1/ko not_active Expired - Fee Related
- 1999-09-17 ID IDW20010682A patent/ID28896A/id unknown
- 1999-09-17 CN CNB2004100384351A patent/CN100506821C/zh not_active Expired - Fee Related
- 1999-09-17 HK HK02100042.6A patent/HK1038360B/en not_active IP Right Cessation
- 1999-09-17 AU AU61920/99A patent/AU763463B2/en not_active Expired
- 1999-09-17 TR TR2001/00805T patent/TR200100805T2/xx unknown
- 1999-09-17 RS YUP-214/01A patent/RS50145B/sr unknown
- 1999-09-17 US US09/582,212 patent/US6436953B1/en not_active Expired - Lifetime
- 1999-09-17 EE EEP200100172A patent/EE04677B1/xx not_active IP Right Cessation
- 1999-09-17 GE GEAP19995786A patent/GEP20032926B/en unknown
- 1999-09-17 WO PCT/EP1999/006899 patent/WO2000017200A1/en not_active Ceased
- 1999-09-17 HR HR20010224A patent/HRP20010224A2/hr not_active Application Discontinuation
- 1999-09-17 CA CA002344251A patent/CA2344251A1/en not_active Abandoned
- 1999-09-17 AT AT99948776T patent/ATE231862T1/de not_active IP Right Cessation
- 1999-09-17 NZ NZ510610A patent/NZ510610A/en unknown
- 1999-09-17 JP JP2000574109A patent/JP4145492B2/ja not_active Expired - Lifetime
- 1999-09-17 BR BR9914044-6A patent/BR9914044A/pt not_active Application Discontinuation
- 1999-09-17 EP EP99948776A patent/EP1115725B1/en not_active Expired - Lifetime
- 1999-09-17 SI SI9930207T patent/SI1115725T1/xx unknown
- 1999-09-17 EA EA200100315A patent/EA005377B1/ru not_active IP Right Cessation
- 1999-09-17 SK SK399-2001A patent/SK285165B6/sk not_active IP Right Cessation
- 1999-09-17 PT PT99948776T patent/PT1115725E/pt unknown
- 1999-09-17 IL IL14206399A patent/IL142063A0/xx active IP Right Grant
-
2001
- 2001-02-19 BG BG105270A patent/BG65195B1/bg unknown
- 2001-03-12 NO NO20011243A patent/NO317304B1/no not_active IP Right Cessation
- 2001-03-18 IL IL142063A patent/IL142063A/en not_active IP Right Cessation
-
2002
- 2002-03-25 US US10/103,733 patent/US6696460B2/en not_active Expired - Lifetime
-
2004
- 2004-02-23 US US10/783,512 patent/US7105676B2/en not_active Expired - Lifetime
-
2006
- 2006-07-27 US US11/493,707 patent/US7393860B1/en not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040630 Termination date: 20091019 |