ES2191464T3 - Tetrahidropiridoeteres. - Google Patents

Tetrahidropiridoeteres.

Info

Publication number
ES2191464T3
ES2191464T3 ES99948776T ES99948776T ES2191464T3 ES 2191464 T3 ES2191464 T3 ES 2191464T3 ES 99948776 T ES99948776 T ES 99948776T ES 99948776 T ES99948776 T ES 99948776T ES 2191464 T3 ES2191464 T3 ES 2191464T3
Authority
ES
Spain
Prior art keywords
hydroxyl
tetrahydropiridoeteres
methoxypropoxy
methoxyethoxy
isopropoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99948776T
Other languages
English (en)
Spanish (es)
Inventor
Stefan Postius
Wolfgang-Alexander Simon
Gerhard Grundler
Guido Hanauer
Reinhard Huber
Wolfgang Kromer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Application granted granted Critical
Publication of ES2191464T3 publication Critical patent/ES2191464T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES99948776T 1998-09-23 1999-09-17 Tetrahidropiridoeteres. Expired - Lifetime ES2191464T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23

Publications (1)

Publication Number Publication Date
ES2191464T3 true ES2191464T3 (es) 2003-09-01

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99948776T Expired - Lifetime ES2191464T3 (es) 1998-09-23 1999-09-17 Tetrahidropiridoeteres.

Country Status (31)

Country Link
US (4) US6436953B1 (cg-RX-API-DMAC7.html)
EP (1) EP1115725B1 (cg-RX-API-DMAC7.html)
JP (1) JP4145492B2 (cg-RX-API-DMAC7.html)
KR (1) KR100668400B1 (cg-RX-API-DMAC7.html)
CN (2) CN1155598C (cg-RX-API-DMAC7.html)
AT (1) ATE231862T1 (cg-RX-API-DMAC7.html)
AU (1) AU763463B2 (cg-RX-API-DMAC7.html)
BG (1) BG65195B1 (cg-RX-API-DMAC7.html)
BR (1) BR9914044A (cg-RX-API-DMAC7.html)
CA (1) CA2344251A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ292335B6 (cg-RX-API-DMAC7.html)
DE (1) DE69905178T2 (cg-RX-API-DMAC7.html)
DK (1) DK1115725T3 (cg-RX-API-DMAC7.html)
EA (1) EA005377B1 (cg-RX-API-DMAC7.html)
EE (1) EE04677B1 (cg-RX-API-DMAC7.html)
ES (1) ES2191464T3 (cg-RX-API-DMAC7.html)
GE (1) GEP20032926B (cg-RX-API-DMAC7.html)
HK (1) HK1038360B (cg-RX-API-DMAC7.html)
HR (1) HRP20010224A2 (cg-RX-API-DMAC7.html)
HU (1) HUP0102990A3 (cg-RX-API-DMAC7.html)
ID (1) ID28896A (cg-RX-API-DMAC7.html)
IL (2) IL142063A0 (cg-RX-API-DMAC7.html)
NO (1) NO317304B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ510610A (cg-RX-API-DMAC7.html)
PL (1) PL193616B1 (cg-RX-API-DMAC7.html)
PT (1) PT1115725E (cg-RX-API-DMAC7.html)
RS (1) RS50145B (cg-RX-API-DMAC7.html)
SI (1) SI1115725T1 (cg-RX-API-DMAC7.html)
SK (1) SK285165B6 (cg-RX-API-DMAC7.html)
TR (1) TR200100805T2 (cg-RX-API-DMAC7.html)
WO (1) WO2000017200A1 (cg-RX-API-DMAC7.html)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ292335B6 (cs) 1998-09-23 2003-09-17 Altana Pharma Ag Tetrahydropyridoethery, jejich použití a farmaceutický prostředek
US6503923B1 (en) 1999-04-17 2003-01-07 Altana Pharma Ag Haloalkoxy imidazonaphthyridines
CA2285516C (en) * 1999-05-12 2010-12-07 President And Fellows Of Harvard College Dopamine transporter imaging agents
MXPA02009549A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Imidazopiridinas triciclicas.
ATE311389T1 (de) * 2000-03-29 2005-12-15 Altana Pharma Ag Wirkstoffvorläufer von imidazopyridin-derivaten
CN1692113A (zh) * 2000-10-25 2005-11-02 奥坦纳医药公司 作为胃分泌抑制剂的多取代咪唑并吡啶
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
WO2002069968A1 (en) * 2001-03-08 2002-09-12 Astrazeneca Ab New use
EP1414821B1 (en) 2001-08-02 2006-08-16 ALTANA Pharma AG Tricyclic epoxides
CN1656096A (zh) * 2001-08-03 2005-08-17 奥坦纳医药公司 用于治疗胃肠病症的烷基-取代的咪唑吡啶
WO2003014120A1 (en) * 2001-08-03 2003-02-20 Altana Pharma Ag Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases
EP1476445A1 (en) 2002-02-15 2004-11-17 ALTANA Pharma AG Tricyclic n-acyl compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
AU2003227710A1 (en) * 2002-05-07 2003-11-11 Altana Pharma Ag New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
MXPA05005117A (es) 2002-11-19 2005-07-01 Altana Pharma Ag Imidazopiridinas 8-sustituidas.
US7879833B2 (en) 2002-12-12 2011-02-01 Nycomed Gmbh Combination medicament
KR20050088176A (ko) * 2002-12-20 2005-09-02 알타나 파마 아게 8-트리알킬실록시-2-메틸-9-페닐-7-옥소-7,8,9,10-테트라히드로이미다조[1,2-h][1,7]나프티리딘
EP1599175A2 (en) * 2003-02-17 2005-11-30 ALTANA Pharma AG Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders
MXPA04008070A (es) 2003-03-10 2004-11-26 Altana Pharma Ag Novedoso proceso para la preparacion de roflumilasto.
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
AU2004268641A1 (en) * 2003-08-29 2005-03-10 Dynogen Pharmaceuticals, Inc. Compositions useful for treating gastrointestinal motility disorders
ES2452691T5 (es) 2003-09-16 2022-09-14 Covis Pharma Gmbh Uso de ciclesonida para el tratamiento de enfermedades respiratorias
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
AU2004298453A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
PL1784404T3 (pl) 2004-09-03 2012-04-30 Yuhan Corp Pochodne pirolo[2,3-c]pirydyny i sposoby ich wytwarzania
EP1784403B1 (en) 2004-09-03 2013-07-17 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
US8148529B2 (en) 2004-09-03 2012-04-03 Yuhan Corporation Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof
JP5383183B2 (ja) * 2005-03-16 2014-01-08 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング ロフルミラストを含有する矯味された剤形
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
WO2011004882A1 (ja) * 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
KR101699145B1 (ko) * 2012-06-15 2017-02-03 (주)바이오팜솔루션즈 페닐알킬설파메이트 화합물 및 이를 포함하는 근육 이완제 조성물
EP3054949A1 (en) 2013-10-08 2016-08-17 Katairo GmbH Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
DE3855692D1 (de) 1987-07-16 1997-01-16 Byk Gulden Lomberg Chem Fab Imidazo[1,2-a]pyridine
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
AU702166B2 (en) * 1994-07-28 1999-02-18 Byk Gulden Lomberg Chemische Fabrik Gmbh Acylimidazopyridines
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
CU23088A3 (es) * 1997-03-24 2005-10-19 Altana Pharma Ag Compuestos de tetra-hidropiridina.
CZ292335B6 (cs) 1998-09-23 2003-09-17 Altana Pharma Ag Tetrahydropyridoethery, jejich použití a farmaceutický prostředek

Also Published As

Publication number Publication date
HK1038360A1 (en) 2002-03-15
NO20011243D0 (no) 2001-03-12
ID28896A (id) 2001-07-12
AU763463B2 (en) 2003-07-24
PL193616B1 (pl) 2007-02-28
US6436953B1 (en) 2002-08-20
IL142063A (en) 2007-10-31
US7105676B2 (en) 2006-09-12
HRP20010224A2 (en) 2002-04-30
TR200100805T2 (tr) 2001-08-21
CZ292335B6 (cs) 2003-09-17
NO317304B1 (no) 2004-10-04
CN1319101A (zh) 2001-10-24
HK1038360B (en) 2003-05-16
AU6192099A (en) 2000-04-10
WO2000017200A1 (en) 2000-03-30
HUP0102990A3 (en) 2002-09-30
US6696460B2 (en) 2004-02-24
NZ510610A (en) 2003-07-25
EP1115725A1 (en) 2001-07-18
KR20010075223A (ko) 2001-08-09
ATE231862T1 (de) 2003-02-15
SK285165B6 (sk) 2006-07-07
JP2002526499A (ja) 2002-08-20
BR9914044A (pt) 2001-12-04
EA200100315A1 (ru) 2001-10-22
CN1560055A (zh) 2005-01-05
SK3992001A3 (en) 2001-12-03
DK1115725T3 (da) 2003-06-23
EE200100172A (et) 2002-06-17
EE04677B1 (et) 2006-08-15
PL346617A1 (en) 2002-02-25
US7393860B1 (en) 2008-07-01
CN100506821C (zh) 2009-07-01
HUP0102990A2 (hu) 2002-01-28
US20040162310A1 (en) 2004-08-19
CA2344251A1 (en) 2000-03-30
RS50145B (sr) 2009-03-25
BG65195B1 (bg) 2007-06-29
PT1115725E (pt) 2003-06-30
JP4145492B2 (ja) 2008-09-03
US20020169320A1 (en) 2002-11-14
CZ20011082A3 (cs) 2001-09-12
IL142063A0 (en) 2002-03-10
CN1155598C (zh) 2004-06-30
BG105270A (en) 2001-11-30
EA005377B1 (ru) 2005-02-24
NO20011243L (no) 2001-03-12
EP1115725B1 (en) 2003-01-29
SI1115725T1 (en) 2003-06-30
DE69905178D1 (de) 2003-03-06
KR100668400B1 (ko) 2007-01-17
DE69905178T2 (de) 2003-07-17
GEP20032926B (en) 2003-03-25
YU21401A (sh) 2004-03-12

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