CN1149998C - 布地奈德和福莫特罗的新用途 - Google Patents
布地奈德和福莫特罗的新用途 Download PDFInfo
- Publication number
- CN1149998C CN1149998C CNB988093103A CN98809310A CN1149998C CN 1149998 C CN1149998 C CN 1149998C CN B988093103 A CNB988093103 A CN B988093103A CN 98809310 A CN98809310 A CN 98809310A CN 1149998 C CN1149998 C CN 1149998C
- Authority
- CN
- China
- Prior art keywords
- active component
- formoterol
- weight portions
- mixture
- budesonide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9703407A SE9703407D0 (sv) | 1997-09-19 | 1997-09-19 | New use |
| SE97034078 | 1997-09-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1271287A CN1271287A (zh) | 2000-10-25 |
| CN1149998C true CN1149998C (zh) | 2004-05-19 |
Family
ID=20408325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB988093103A Expired - Lifetime CN1149998C (zh) | 1997-09-19 | 1998-09-09 | 布地奈德和福莫特罗的新用途 |
Country Status (38)
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9703407D0 (sv) | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
| SE9802073D0 (sv) | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
| CA2347856C (en) * | 1998-11-13 | 2009-02-17 | Jago Research Ag | Dry powder for inhalation |
| US6004537A (en) * | 1998-12-18 | 1999-12-21 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol |
| GB9928311D0 (en) * | 1999-11-30 | 2000-01-26 | Novartis Ag | Organic compounds |
| GB0009584D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Pharmaceutical compositions |
| GB0012261D0 (en) | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel process |
| GB0012260D0 (en) | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel composition |
| DE60221640T2 (de) * | 2001-02-06 | 2008-05-21 | Innovata Biomed Ltd., St. Albans | Bimodale trockenpulverzusammensetzung zur inhalation |
| US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| SE0200312D0 (sv) | 2002-02-01 | 2002-02-01 | Astrazeneca Ab | Novel composition |
| CA2500065A1 (en) * | 2002-09-30 | 2004-04-15 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
| US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
| US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| ES2384641T3 (es) | 2005-07-14 | 2012-07-10 | Lithera, Inc. | Formulación lipolítica que potencia la liberación mantenida para el tratamiento localizado del tejido adiposo |
| EP1978933A2 (en) * | 2005-12-15 | 2008-10-15 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for oral administration |
| US7913223B2 (en) * | 2005-12-16 | 2011-03-22 | Dialogic Corporation | Method and system for development and use of a user-interface for operations, administration, maintenance and provisioning of a telecommunications system |
| GB0604141D0 (en) * | 2006-03-01 | 2006-04-12 | Arrow Int Ltd | Nebulizer formulation |
| JP2010506941A (ja) * | 2006-10-17 | 2010-03-04 | リセラ，インク． | 甲状腺眼症の治療のための方法、組成物及び製剤 |
| US9132084B2 (en) * | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| LT2435025T (lt) | 2009-05-29 | 2016-09-26 | Pearl Therapeutics, Inc. | Veikliosios medžiagos tiekimas per kvėpavimo takus |
| WO2010144628A2 (en) * | 2009-06-09 | 2010-12-16 | Elevation Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration |
| CN102000090A (zh) * | 2009-08-31 | 2011-04-06 | 北京利乐生制药科技有限公司 | 一种以布地奈德与阿福特罗为活性成分的复方制剂 |
| KR20120113267A (ko) * | 2010-01-15 | 2012-10-12 | 리쎄라 인코오포레이티드 | 동결건조 케이크 제제 |
| EA201270784A1 (ru) | 2010-11-24 | 2013-04-30 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Монотерапевтические композиции селективного липофильного и бета-агониста длительного действия и способы косметического лечения ожирения и контурного выпячивания |
| CA2830069C (en) | 2011-03-20 | 2019-11-12 | The University Of British Columbia | Therapeutic agent for emphysema and copd |
| CN102362860A (zh) * | 2011-10-27 | 2012-02-29 | 江阴长风医药科技有限公司 | 以氢氟烷烃为抛射剂的布地奈德和福莫特罗气雾剂制剂 |
| JP6454323B2 (ja) | 2013-03-15 | 2019-01-16 | パール セラピューティクス，インコーポレイテッド | 粒子状結晶性材料のコンディショニングのための方法及びシステム |
| ITMI20130571A1 (it) * | 2013-04-10 | 2014-10-11 | Zambon Spa | Composizione farmaceutica contenente budesonide e formoterolo |
| WO2015065220A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких и способ его получения |
| GB201321717D0 (en) | 2013-12-09 | 2014-01-22 | Pharmachemie Bv | Inhalable Medicaments |
| GB201321712D0 (en) | 2013-12-09 | 2014-01-22 | Pharmachemie Bv | Dry Powder Inhaler |
| GB201408387D0 (en) * | 2014-05-12 | 2014-06-25 | Teva Pharmaceuticals Europ B V | Treatment of respiratory disorders |
| CA3007050C (en) | 2015-12-04 | 2020-12-08 | Mexichem Fluor S.A. De C.V. | Pharmaceutical composition comprising a formoterol compound |
| AU2019287541A1 (en) | 2018-06-14 | 2021-01-21 | Astrazeneca Uk Limited | Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition |
| WO2021048171A1 (en) * | 2019-09-10 | 2021-03-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method to improve phagocytosis |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2235626B (en) | 1989-09-08 | 1994-02-09 | Glaxo Group Ltd | Inhalation medicaments for treating respiratory disorders |
| IL95590A (en) | 1989-09-08 | 1996-06-18 | Glaxo Group Ltd | Medicinal preparations containing Salmetrol and Pluticasone Propionate |
| US5250286A (en) | 1990-05-07 | 1993-10-05 | Aegis Technology, Inc. | Treatment of chronic obstructive pulmonary disease (COPD) by inhalation of an imidazoline |
| PL164294B1 (pl) | 1990-12-20 | 1994-07-29 | Inst Farmaceutyczny | Sposób otrzymywania diastereoizomeru /22R/-16a , 17a-butylidenodioksy-11 ß 21-dihydroksy-1,4-pregnadien-3,20-dionu PL |
| US5795564A (en) | 1991-04-05 | 1998-08-18 | Sepracor, Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
| US5444521A (en) | 1991-07-15 | 1995-08-22 | Canon Kabushiki Kaisha | Image fixing device capable of controlling heating overshoot |
| EP1086697A2 (en) | 1991-12-18 | 2001-03-28 | AstraZeneca AB | New combination of formoterol and budesonide |
| NZ246050A (en) * | 1991-12-18 | 1995-12-21 | Astra Ab Formerly Aktiebolaget | Medicament containing formoterol and budesonide for treatment of respiratory disorders |
| SE9404080L (sv) | 1993-12-28 | 1995-06-29 | Ciba Geigy Ag | Förfarande för framställning av en optiskt ren enantiomer av formoterol |
| SE9700134D0 (sv) | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
| US5983956A (en) | 1994-10-03 | 1999-11-16 | Astra Aktiebolag | Formulation for inhalation |
| GB9519692D0 (en) | 1995-09-27 | 1995-11-29 | Quillin Helen | Atomising nozzle |
| CA2238298A1 (en) * | 1995-11-24 | 1997-06-19 | Luca Francesco Raveglia | Quinoline derivatives |
| SE9603669D0 (sv) | 1996-10-08 | 1996-10-08 | Astra Ab | New combination |
| SE9700135D0 (sv) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
| PL337722A1 (en) | 1997-06-27 | 2000-08-28 | Astra Ab | Novel combination antiasthmatic drugs |
| SE9703407D0 (sv) * | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
| US6598603B1 (en) * | 1997-12-31 | 2003-07-29 | Astra Aktiebolag | Method for treating respiratory diseases |
| SE9802073D0 (sv) | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
| DZ2947A1 (fr) | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
| US6004537A (en) | 1998-12-18 | 1999-12-21 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol |
| SE9900834D0 (sv) | 1999-03-09 | 1999-03-09 | Astra Ab | Novel combination |
-
1997
- 1997-09-19 SE SE9703407A patent/SE9703407D0/xx unknown
-
1998
- 1998-09-09 DK DK02001670T patent/DK1210943T3/da active
- 1998-09-09 PT PT02001670T patent/PT1210943E/pt unknown
- 1998-09-09 RU RU2000106597/14A patent/RU2199322C2/ru active
- 1998-09-09 KR KR1020007002900A patent/KR20010024140A/ko not_active Application Discontinuation
- 1998-09-09 EP EP02001670A patent/EP1210943B1/en not_active Revoked
- 1998-09-09 IL IL13477398A patent/IL134773A/xx not_active IP Right Cessation
- 1998-09-09 AT AT02001670T patent/ATE329599T1/de not_active IP Right Cessation
- 1998-09-09 DE DE69807239T patent/DE69807239T2/de not_active Revoked
- 1998-09-09 ES ES02001670T patent/ES2266322T3/es not_active Expired - Lifetime
- 1998-09-09 ID IDW20000506A patent/ID24838A/id unknown
- 1998-09-09 HU HU0003848A patent/HUP0003848A2/hu not_active Application Discontinuation
- 1998-09-09 MX MXPA00002615A patent/MXPA00002615A/es active IP Right Grant
- 1998-09-09 JP JP2000512551A patent/JP2001517630A/ja active Pending
- 1998-09-09 SI SI9830272T patent/SI1014993T1/xx unknown
- 1998-09-09 ES ES98944373T patent/ES2182357T3/es not_active Expired - Lifetime
- 1998-09-09 CA CA2302700A patent/CA2302700C/en not_active Expired - Lifetime
- 1998-09-09 AT AT98944373T patent/ATE222106T1/de not_active IP Right Cessation
- 1998-09-09 EP EP98944373A patent/EP1014993B1/en not_active Revoked
- 1998-09-09 EE EEP200000145A patent/EE04297B1/xx unknown
- 1998-09-09 BR BR9812325-4A patent/BR9812325A/pt not_active Application Discontinuation
- 1998-09-09 CZ CZ2000950A patent/CZ295250B6/cs not_active IP Right Cessation
- 1998-09-09 CN CNB988093103A patent/CN1149998C/zh not_active Expired - Lifetime
- 1998-09-09 NZ NZ503173A patent/NZ503173A/en not_active IP Right Cessation
- 1998-09-09 WO PCT/SE1998/001599 patent/WO1999015182A1/en not_active Application Discontinuation
- 1998-09-09 SK SK389-2000A patent/SK285330B6/sk not_active IP Right Cessation
- 1998-09-09 TR TR2000/00726T patent/TR200000726T2/xx unknown
- 1998-09-09 DK DK98944373T patent/DK1014993T3/da active
- 1998-09-09 DE DE69834955T patent/DE69834955T2/de not_active Revoked
- 1998-09-09 PL PL339295A patent/PL190782B1/pl unknown
- 1998-09-09 PT PT98944373T patent/PT1014993E/pt unknown
- 1998-09-09 UA UA2000031372A patent/UA72446C2/uk unknown
- 1998-09-09 AU AU91928/98A patent/AU757235B2/en not_active Expired
- 1998-09-09 SI SI9830844T patent/SI1210943T1/sl unknown
- 1998-09-16 TW TW087115428A patent/TW546140B/zh not_active IP Right Cessation
- 1998-09-16 IN IN2781DE1998 patent/IN190791B/en unknown
- 1998-09-17 ZA ZA988516A patent/ZA988516B/xx unknown
- 1998-09-18 MY MYPI98004288A patent/MY127812A/en unknown
- 1998-09-18 AR ARP980104682A patent/AR013506A1/es unknown
- 1998-11-18 SA SA98190773A patent/SA98190773B1/ar unknown
-
2000
- 2000-03-15 IS IS5407A patent/IS2715B/is unknown
- 2000-03-17 NO NO20001401A patent/NO327176B1/no not_active IP Right Cessation
-
2001
- 2001-11-13 US US10/010,283 patent/US7897646B2/en not_active Expired - Fee Related
-
2002
- 2002-10-03 HK HK02107290.0A patent/HK1045812B/zh not_active IP Right Cessation
-
2006
- 2006-09-12 CY CY20061101297T patent/CY1106156T1/el unknown
-
2010
- 2010-12-30 US US12/982,360 patent/US8461211B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: ASTRAZENECA AB Free format text: FORMER NAME: ASTRA AKTIEBOLAG |
|
| CP01 | Change in the name or title of a patent holder |
Address after: Swedish Sodertalje Patentee after: Astrazeneca (Sweden) AB Address before: Swedish Sodertalje Patentee before: Astra Aktiebolag |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20040519 |