CN114711402A - 一种适用肠胃患者多维营养素配方 - Google Patents
一种适用肠胃患者多维营养素配方 Download PDFInfo
- Publication number
- CN114711402A CN114711402A CN202210295642.3A CN202210295642A CN114711402A CN 114711402 A CN114711402 A CN 114711402A CN 202210295642 A CN202210295642 A CN 202210295642A CN 114711402 A CN114711402 A CN 114711402A
- Authority
- CN
- China
- Prior art keywords
- parts
- vitamin
- gastrointestinal
- seed
- cabbage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 29
- 230000002496 gastric effect Effects 0.000 title claims abstract description 28
- 229940088594 vitamin Drugs 0.000 title claims abstract description 24
- 239000011782 vitamin Substances 0.000 title claims abstract description 24
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 claims abstract description 32
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 claims abstract description 24
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 claims abstract description 24
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 24
- 244000268590 Euryale ferox Species 0.000 claims abstract description 21
- 235000006487 Euryale ferox Nutrition 0.000 claims abstract description 21
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 19
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 19
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 19
- 235000002767 Daucus carota Nutrition 0.000 claims abstract description 18
- 244000000626 Daucus carota Species 0.000 claims abstract description 18
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 18
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 18
- 240000003768 Solanum lycopersicum Species 0.000 claims abstract description 18
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 17
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 17
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 17
- 235000001188 Peltandra virginica Nutrition 0.000 claims abstract description 16
- 244000077995 Coix lacryma jobi Species 0.000 claims abstract description 13
- 235000014693 Fagopyrum tataricum Nutrition 0.000 claims abstract description 13
- 244000130270 Fagopyrum tataricum Species 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 235000007542 Cichorium intybus Nutrition 0.000 claims abstract description 12
- 240000007124 Brassica oleracea Species 0.000 claims abstract 5
- 244000298479 Cichorium intybus Species 0.000 claims abstract 4
- 244000178937 Brassica oleracea var. capitata Species 0.000 claims description 29
- 235000000832 Ayote Nutrition 0.000 claims description 25
- 235000009854 Cucurbita moschata Nutrition 0.000 claims description 25
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 claims description 25
- 235000015136 pumpkin Nutrition 0.000 claims description 25
- 240000001980 Cucurbita pepo Species 0.000 claims description 24
- 244000197580 Poria cocos Species 0.000 claims description 23
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 claims description 22
- 229930003231 vitamin Natural products 0.000 claims description 20
- 235000013343 vitamin Nutrition 0.000 claims description 20
- 235000016709 nutrition Nutrition 0.000 claims description 17
- 244000302512 Momordica charantia Species 0.000 claims description 16
- 235000009811 Momordica charantia Nutrition 0.000 claims description 16
- 235000007319 Avena orientalis Nutrition 0.000 claims description 15
- 230000035764 nutrition Effects 0.000 claims description 15
- 240000007087 Apium graveolens Species 0.000 claims description 14
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 claims description 14
- 235000010591 Appio Nutrition 0.000 claims description 14
- 240000005979 Hordeum vulgare Species 0.000 claims description 14
- 235000007340 Hordeum vulgare Nutrition 0.000 claims description 14
- 235000009337 Spinacia oleracea Nutrition 0.000 claims description 14
- 235000021537 Beetroot Nutrition 0.000 claims description 13
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 12
- 240000008067 Cucumis sativus Species 0.000 claims description 11
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims description 11
- 239000004386 Erythritol Substances 0.000 claims description 11
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims description 11
- 229940009714 erythritol Drugs 0.000 claims description 11
- 235000019414 erythritol Nutrition 0.000 claims description 11
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims description 11
- 244000017020 Ipomoea batatas Species 0.000 claims description 10
- 235000002678 Ipomoea batatas Nutrition 0.000 claims description 10
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 10
- 241000371652 Curvularia clavata Species 0.000 claims description 9
- 235000009812 Momordica cochinchinensis Nutrition 0.000 claims description 9
- 235000018365 Momordica dioica Nutrition 0.000 claims description 9
- 235000021329 brown rice Nutrition 0.000 claims description 9
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 8
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 8
- 239000000811 xylitol Substances 0.000 claims description 8
- 235000010447 xylitol Nutrition 0.000 claims description 8
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 8
- 229960002675 xylitol Drugs 0.000 claims description 8
- 235000008322 Trichosanthes cucumerina Nutrition 0.000 claims description 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 6
- 244000300264 Spinacia oleracea Species 0.000 claims description 6
- 229930003316 Vitamin D Natural products 0.000 claims description 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- 229960000304 folic acid Drugs 0.000 claims description 6
- 235000019152 folic acid Nutrition 0.000 claims description 6
- 239000011724 folic acid Substances 0.000 claims description 6
- 235000019166 vitamin D Nutrition 0.000 claims description 6
- 239000011710 vitamin D Substances 0.000 claims description 6
- 229940046008 vitamin d Drugs 0.000 claims description 6
- 241000283690 Bos taurus Species 0.000 claims description 5
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 5
- 210000000988 bone and bone Anatomy 0.000 claims description 5
- 229940013618 stevioside Drugs 0.000 claims description 5
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 5
- 235000019202 steviosides Nutrition 0.000 claims description 5
- 208000018522 Gastrointestinal disease Diseases 0.000 claims description 4
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 claims description 4
- 229940107187 fructooligosaccharide Drugs 0.000 claims description 4
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 claims description 4
- 244000228451 Stevia rebaudiana Species 0.000 claims description 3
- 235000006092 Stevia rebaudiana Nutrition 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- 229930182470 glycoside Natural products 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 3
- -1 vitamin D glycoside Chemical class 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 244000088415 Raphanus sativus Species 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 38
- 210000000952 spleen Anatomy 0.000 abstract description 35
- 150000004676 glycans Chemical class 0.000 abstract description 14
- 229920001282 polysaccharide Polymers 0.000 abstract description 14
- 239000005017 polysaccharide Substances 0.000 abstract description 14
- 210000003734 kidney Anatomy 0.000 abstract description 13
- 241000894006 Bacteria Species 0.000 abstract description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 11
- 206010012735 Diarrhoea Diseases 0.000 abstract description 10
- 235000013399 edible fruits Nutrition 0.000 abstract description 10
- 230000007812 deficiency Effects 0.000 abstract description 7
- 201000010099 disease Diseases 0.000 abstract description 7
- 235000009508 confectionery Nutrition 0.000 abstract description 6
- 230000007935 neutral effect Effects 0.000 abstract description 6
- 230000012010 growth Effects 0.000 abstract description 5
- 230000027939 micturition Effects 0.000 abstract description 5
- 235000019640 taste Nutrition 0.000 abstract description 5
- 208000008967 Enuresis Diseases 0.000 abstract description 3
- 206010041497 Spermatorrhoea Diseases 0.000 abstract description 3
- 208000019902 chronic diarrheal disease Diseases 0.000 abstract description 3
- 238000002474 experimental method Methods 0.000 abstract description 3
- 210000002700 urine Anatomy 0.000 abstract description 3
- 241000191967 Staphylococcus aureus Species 0.000 abstract description 2
- 230000005764 inhibitory process Effects 0.000 abstract description 2
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 33
- 241000220259 Raphanus Species 0.000 description 19
- 235000013325 dietary fiber Nutrition 0.000 description 18
- 230000000968 intestinal effect Effects 0.000 description 18
- 230000006870 function Effects 0.000 description 14
- 238000011160 research Methods 0.000 description 13
- 229930003270 Vitamin B Natural products 0.000 description 12
- 235000019156 vitamin B Nutrition 0.000 description 12
- 239000011720 vitamin B Substances 0.000 description 12
- 235000013305 food Nutrition 0.000 description 11
- 230000001105 regulatory effect Effects 0.000 description 11
- 239000003814 drug Substances 0.000 description 10
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical group O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 9
- 229920002498 Beta-glucan Polymers 0.000 description 9
- 230000001737 promoting effect Effects 0.000 description 9
- 210000002784 stomach Anatomy 0.000 description 9
- 241000723343 Cichorium Species 0.000 description 8
- 235000002723 Dioscorea alata Nutrition 0.000 description 8
- 235000007056 Dioscorea composita Nutrition 0.000 description 8
- 235000009723 Dioscorea convolvulacea Nutrition 0.000 description 8
- 235000005362 Dioscorea floribunda Nutrition 0.000 description 8
- 235000004868 Dioscorea macrostachya Nutrition 0.000 description 8
- 235000005361 Dioscorea nummularia Nutrition 0.000 description 8
- 235000005360 Dioscorea spiculiflora Nutrition 0.000 description 8
- 244000281702 Dioscorea villosa Species 0.000 description 8
- 241000219315 Spinacia Species 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 8
- 230000006378 damage Effects 0.000 description 8
- 235000004879 dioscorea Nutrition 0.000 description 8
- 241000699666 Mus <mouse, genus> Species 0.000 description 7
- 230000029087 digestion Effects 0.000 description 7
- 230000036541 health Effects 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 235000013311 vegetables Nutrition 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 6
- 210000001072 colon Anatomy 0.000 description 6
- 230000001965 increasing effect Effects 0.000 description 6
- 230000002401 inhibitory effect Effects 0.000 description 6
- 235000018102 proteins Nutrition 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 6
- 150000003648 triterpenes Chemical class 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 5
- 241000700159 Rattus Species 0.000 description 5
- 230000003078 antioxidant effect Effects 0.000 description 5
- 230000009286 beneficial effect Effects 0.000 description 5
- 239000000284 extract Substances 0.000 description 5
- 230000005176 gastrointestinal motility Effects 0.000 description 5
- 239000001814 pectin Substances 0.000 description 5
- 229920001277 pectin Polymers 0.000 description 5
- 235000010987 pectin Nutrition 0.000 description 5
- 206010010774 Constipation Diseases 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 206010019663 Hepatic failure Diseases 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 241000186604 Lactobacillus reuteri Species 0.000 description 4
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 4
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 239000003963 antioxidant agent Substances 0.000 description 4
- 235000006708 antioxidants Nutrition 0.000 description 4
- 230000008602 contraction Effects 0.000 description 4
- 230000013872 defecation Effects 0.000 description 4
- 208000035475 disorder Diseases 0.000 description 4
- 210000002216 heart Anatomy 0.000 description 4
- 230000036039 immunity Effects 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 229940001882 lactobacillus reuteri Drugs 0.000 description 4
- 208000007903 liver failure Diseases 0.000 description 4
- 231100000835 liver failure Toxicity 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- PGZCJOPTDHWYES-UHFFFAOYSA-N methyl 1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylate Chemical compound CC(C)C1=CC=C2C3(C)CCCC(C(=O)OC)(C)C3CCC2=C1 PGZCJOPTDHWYES-UHFFFAOYSA-N 0.000 description 4
- 230000008855 peristalsis Effects 0.000 description 4
- 239000011591 potassium Substances 0.000 description 4
- 229910052700 potassium Inorganic materials 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- SUVMJBTUFCVSAD-UHFFFAOYSA-N sulforaphane Chemical compound CS(=O)CCCCN=C=S SUVMJBTUFCVSAD-UHFFFAOYSA-N 0.000 description 4
- 235000020985 whole grains Nutrition 0.000 description 4
- 108091006146 Channels Proteins 0.000 description 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 3
- 208000007107 Stomach Ulcer Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 229930003268 Vitamin C Natural products 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 235000013339 cereals Nutrition 0.000 description 3
- 230000002950 deficient Effects 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000037213 diet Effects 0.000 description 3
- 235000020979 dietary recommendations Nutrition 0.000 description 3
- 210000002249 digestive system Anatomy 0.000 description 3
- 235000020776 essential amino acid Nutrition 0.000 description 3
- 239000003797 essential amino acid Substances 0.000 description 3
- 201000005917 gastric ulcer Diseases 0.000 description 3
- 230000007160 gastrointestinal dysfunction Effects 0.000 description 3
- 208000014617 hemorrhoid Diseases 0.000 description 3
- 230000007358 intestinal barrier function Effects 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 230000000050 nutritive effect Effects 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 239000006041 probiotic Substances 0.000 description 3
- 235000018291 probiotics Nutrition 0.000 description 3
- 230000002040 relaxant effect Effects 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 210000000813 small intestine Anatomy 0.000 description 3
- 230000004936 stimulating effect Effects 0.000 description 3
- 235000019722 synbiotics Nutrition 0.000 description 3
- 208000011580 syndromic disease Diseases 0.000 description 3
- 230000009466 transformation Effects 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 235000019154 vitamin C Nutrition 0.000 description 3
- 239000011718 vitamin C Substances 0.000 description 3
- SUVMJBTUFCVSAD-JTQLQIEISA-N 4-Methylsulfinylbutyl isothiocyanate Natural products C[S@](=O)CCCCN=C=S SUVMJBTUFCVSAD-JTQLQIEISA-N 0.000 description 2
- 102000012002 Aquaporin 4 Human genes 0.000 description 2
- 108010036280 Aquaporin 4 Proteins 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000186000 Bifidobacterium Species 0.000 description 2
- 241000219193 Brassicaceae Species 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 235000005979 Citrus limon Nutrition 0.000 description 2
- 244000131522 Citrus pyriformis Species 0.000 description 2
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 2
- 208000036649 Dysbacteriosis Diseases 0.000 description 2
- 208000027244 Dysbiosis Diseases 0.000 description 2
- 208000037487 Endotoxemia Diseases 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000003676 Glucocorticoid Receptors Human genes 0.000 description 2
- 108090000079 Glucocorticoid Receptors Proteins 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 description 2
- 208000005016 Intestinal Neoplasms Diseases 0.000 description 2
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 description 2
- 208000002720 Malnutrition Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 102000038030 PI3Ks Human genes 0.000 description 2
- 108091007960 PI3Ks Proteins 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- 244000046052 Phaseolus vulgaris Species 0.000 description 2
- 108090000430 Phosphatidylinositol 3-kinases Proteins 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 108091008611 Protein Kinase B Proteins 0.000 description 2
- 206010067171 Regurgitation Diseases 0.000 description 2
- 229930003448 Vitamin K Natural products 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 235000021120 animal protein Nutrition 0.000 description 2
- 230000003474 anti-emetic effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 150000001746 carotenes Chemical class 0.000 description 2
- 235000005473 carotenes Nutrition 0.000 description 2
- 210000004534 cecum Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 2
- 239000002027 dichloromethane extract Substances 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 230000007140 dysbiosis Effects 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000029142 excretion Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 230000007661 gastrointestinal function Effects 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 201000002313 intestinal cancer Diseases 0.000 description 2
- 230000003871 intestinal function Effects 0.000 description 2
- 230000008991 intestinal motility Effects 0.000 description 2
- 210000004347 intestinal mucosa Anatomy 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 235000012661 lycopene Nutrition 0.000 description 2
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 description 2
- 229960004999 lycopene Drugs 0.000 description 2
- 239000001751 lycopene Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 238000010172 mouse model Methods 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 239000008164 mustard oil Substances 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 235000005985 organic acids Nutrition 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 235000021395 porridge Nutrition 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 229960001462 sodium cyclamate Drugs 0.000 description 2
- 229960005559 sulforaphane Drugs 0.000 description 2
- 235000015487 sulforaphane Nutrition 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 2
- 235000019168 vitamin K Nutrition 0.000 description 2
- 239000011712 vitamin K Substances 0.000 description 2
- 150000003721 vitamin K derivatives Chemical class 0.000 description 2
- 229940046010 vitamin k Drugs 0.000 description 2
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 description 1
- GOZMBJCYMQQACI-UHFFFAOYSA-N 6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one;dihydrochloride Chemical compound Cl.Cl.C=1OC2=CC(C)=C(C)C=C2C(=O)C=1CN(C)CCN(C)CC(C1=CC=CC=C11)=CN1C1=CC=CC(C(F)(F)F)=C1 GOZMBJCYMQQACI-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010001497 Agitation Diseases 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 241000208173 Apiaceae Species 0.000 description 1
- 102000004888 Aquaporin 1 Human genes 0.000 description 1
- 108090001004 Aquaporin 1 Proteins 0.000 description 1
- 102000004363 Aquaporin 3 Human genes 0.000 description 1
- 108090000991 Aquaporin 3 Proteins 0.000 description 1
- 102000004392 Aquaporin 5 Human genes 0.000 description 1
- 108090000976 Aquaporin 5 Proteins 0.000 description 1
- 241000209763 Avena sativa Species 0.000 description 1
- 235000007558 Avena sp Nutrition 0.000 description 1
- 241000304886 Bacilli Species 0.000 description 1
- 241000335423 Blastomyces Species 0.000 description 1
- 241000219198 Brassica Species 0.000 description 1
- 235000011331 Brassica Nutrition 0.000 description 1
- 235000011299 Brassica oleracea var botrytis Nutrition 0.000 description 1
- 240000003259 Brassica oleracea var. botrytis Species 0.000 description 1
- 241000252983 Caecum Species 0.000 description 1
- 241000282461 Canis lupus Species 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- 240000006162 Chenopodium quinoa Species 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000035851 Chrysanthemum leucanthemum Species 0.000 description 1
- 241001112696 Clostridia Species 0.000 description 1
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 208000019399 Colonic disease Diseases 0.000 description 1
- 241000219122 Cucurbita Species 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 241000234272 Dioscoreaceae Species 0.000 description 1
- 206010015137 Eructation Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 description 1
- 206010017943 Gastrointestinal conditions Diseases 0.000 description 1
- 208000017228 Gastrointestinal motility disease Diseases 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 206010020710 Hyperphagia Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 235000006350 Ipomoea batatas var. batatas Nutrition 0.000 description 1
- 102000007330 LDL Lipoproteins Human genes 0.000 description 1
- 108010007622 LDL Lipoproteins Proteins 0.000 description 1
- 208000034486 Multi-organ failure Diseases 0.000 description 1
- 208000010718 Multiple Organ Failure Diseases 0.000 description 1
- 108010057466 NF-kappa B Proteins 0.000 description 1
- 102000003945 NF-kappa B Human genes 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 240000004371 Panax ginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010057249 Phagocytosis Diseases 0.000 description 1
- 108010064851 Plant Proteins Proteins 0.000 description 1
- 241000222341 Polyporaceae Species 0.000 description 1
- 102000005765 Proto-Oncogene Proteins c-akt Human genes 0.000 description 1
- 241000283984 Rodentia Species 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- CAMXVZOXBADHNJ-UHFFFAOYSA-N ammonium nitrite Chemical compound [NH4+].[O-]N=O CAMXVZOXBADHNJ-UHFFFAOYSA-N 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 239000010692 aromatic oil Substances 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 229940069780 barley extract Drugs 0.000 description 1
- 235000019998 barley wine Nutrition 0.000 description 1
- 208000027687 belching Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 239000002021 butanolic extract Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 235000015190 carrot juice Nutrition 0.000 description 1
- 230000035568 catharsis Effects 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 239000004464 cereal grain Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 235000017471 coenzyme Q10 Nutrition 0.000 description 1
- 229940110767 coenzyme Q10 Drugs 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 206010009887 colitis Diseases 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 201000010897 colon adenocarcinoma Diseases 0.000 description 1
- 230000008951 colonic inflammation Effects 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 229910000365 copper sulfate Inorganic materials 0.000 description 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000000287 crude extract Substances 0.000 description 1
- 230000001120 cytoprotective effect Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 229920003045 dextran sodium sulfate Polymers 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 235000019007 dietary guidelines Nutrition 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000005686 eating Nutrition 0.000 description 1
- 230000004535 effect on gastrointestinal diseases Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- XGVJWXAYKUHDOO-UHFFFAOYSA-N galanthidine Natural products C1CN2CC3=CC=4OCOC=4C=C3C3C2C1=CC(O)C3O XGVJWXAYKUHDOO-UHFFFAOYSA-N 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000027119 gastric acid secretion Effects 0.000 description 1
- 230000030136 gastric emptying Effects 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 235000019680 high-energy food Nutrition 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 210000005027 intestinal barrier Anatomy 0.000 description 1
- 210000005026 intestinal epithelial barrier Anatomy 0.000 description 1
- 230000007413 intestinal health Effects 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 150000002540 isothiocyanates Chemical class 0.000 description 1
- 210000001630 jejunum Anatomy 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- XGVJWXAYKUHDOO-DANNLKNASA-N lycorine Chemical compound C1CN2CC3=CC=4OCOC=4C=C3[C@H]3[C@H]2C1=C[C@H](O)[C@H]3O XGVJWXAYKUHDOO-DANNLKNASA-N 0.000 description 1
- KQAOMBGKIWRWNA-UHFFFAOYSA-N lycorine Natural products OC1C=C2CCN3C2C(C1O)c4cc5OCOc5cc34 KQAOMBGKIWRWNA-UHFFFAOYSA-N 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000018343 nutrient deficiency Nutrition 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 235000020830 overeating Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000008782 phagocytosis Effects 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- 230000008288 physiological mechanism Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 235000021118 plant-derived protein Nutrition 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000013406 prebiotics Nutrition 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 150000004666 short chain fatty acids Chemical class 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 230000003393 splenic effect Effects 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 235000015113 tomato pastes and purées Nutrition 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
本发明公开了一种适用肠胃患者多维营养素配方，包括以下重量份原料：山药0.1‑0.3份、苦荞0.1‑0.3份、莲子0.17‑0.19份、基础包0.1‑0.2份、芡实0.17‑0.19份、薏苡仁0.06‑0.08份、菊苣1‑2份、茯苓0.1‑0.3份、圆白菜0.11‑0.13份、胡萝卜0.11‑0.13份、西红柿0.11‑0.13份。本发明芡实，归于脾肾经，性味平甘涩，首载于《神农本草经》，具有益肾固精、补脾止泻、除湿止带的疗效，临床广泛用于遗精滑精，遗尿尿频，脾虚久泻，白浊带下等疾病的治疗。李湘利等的实验证实芡实多糖能够抑制细菌生长，而且对于金黄色葡萄球菌抑菌最强。
Description
技术领域
本发明涉及肠胃患者技术领域，具体涉及一种适用肠胃患者多维营养素配方。
背景技术
胃肠道运动是消化系统生理功能的重要组成部分，胃肠功能紊乱是引起消化系统症状的因素之一，研究表明胃肠动力障碍是引起功能性消化不良的常见原因。胃肠道生理病理状态还与机体免疫密切相关。刘崇海等研究发现肠道菌群失调后，迟发型变态反应、脾指数、诱导的淋巴转化率、抗体生成细胞数和脾脏的和基因表达水平均低于正常组。梁庆红等通过灌胃抗生素造成肠道菌群失调模型，结果表明小鼠脾脏的重量减轻，淋巴细胞数量及血清中IL2的含量减低、脾脏溶血空斑数减少、巨噬细胞吞噬率降。说明肠道菌群失调导致机体特异性和非特异性免疫功能均降低。免疫功能下降又会导致机体的二重感染、或新的感染，这些不良后果又可加重菌群紊乱，形成恶性循环。因此，肠道健康与否直接关乎到生命的安危，并且是保证其他器官发挥正常功能的基础。基于此，本发明提供一种适用肠胃患者多维营养素配方。
发明内容
本发明的目的在于提供一种适用肠胃患者多维营养素配方，以解决上述背景技术中提出的问题。
为实现上述目的，本发明提供如下技术方案：
一种适用肠胃患者多维营养素配方，包括以下重量份原料：
山药0.1-0.3份、苦荞0.1-0.3份、莲子0.17-0.19份、基础包0.1-0.2份、芡实0.17-0.19份、薏苡仁0.06-0.08份、菊苣1-2份、茯苓0.1-0.3份、圆白菜0.11-0.13份、胡萝卜0.11-0.13份、西红柿0.11-0.13份、紫甘蓝0.05-0.07份、南瓜0.11-0.13份、芹菜0.05-0.07份、甜菜根0.05-0.07份、白萝卜0.03-0.05份、黄瓜0.11-0.13份、苦瓜0.05-0.07份、菠菜0.11-0.13份、营养包0.5-0.7份、赤藓糖醇0.1-0.3份、木糖醇0.1-0.3份、甜菊糖苷0.002-0.004份、维生素0.04-0.06份、叶酸14-16份。
优选地，所述适用肠胃患者多维营养素配方包括以下重量份原料：
山药0.2-0.3份、苦荞0.2-0.3份、莲子0.18-0.19份、基础包0.12-0.2份、芡实0.18-0.19份、薏苡仁0.07-0.08份、菊苣1.1-2份、茯苓0.2-0.3份、圆白菜0.12-0.13份、胡萝卜0.12-0.13份、西红柿0.12-0.13份、紫甘蓝0.06-0.07份、南瓜0.12-0.13份、芹菜0.06-0.07份、甜菜根0.06-0.07份、白萝卜0.04-0.05份、黄瓜0.12-0.13份、苦瓜0.06-0.07份、菠菜0.12-0.13份、营养包0.6-0.7份、赤藓糖醇0.2-0.3份、木糖醇0.2-0.3份、甜菊糖苷0.003-0.004份、维生素0.05-0.06份、叶酸15-16份。
优选地，所述适用肠胃患者多维营养素配方包括以下重量份原料：
山药0.2份、苦荞0.2份、莲子0.18份、基础包0.15份、芡实0.18份、薏苡仁0.07份、菊苣1.5份、茯苓0.2份、圆白菜0.12份、胡萝卜0.12份、西红柿0.12份、紫甘蓝0.06份、南瓜0.12份、芹菜0.06份、甜菜根0.06份、白萝卜0.04份、黄瓜0.12份、苦瓜0.06份、菠菜0.12份、营养包0.6份、赤藓糖醇0.2份、木糖醇0.25份、甜菊糖苷0.003份、维生素0.05份、叶酸15份。
优选地，所述基础包为青稞0.06-0.08份、燕麦0.06-0.08份、黑米0.05-0.07份、糙米0.06-0.008份、山芋0.1-0.3份。
优选地，所述基础包为青稞0.07份、燕麦0.07份、黑米0.06份、糙米0.07份、山芋0.2份。
优选地，所述营养包为低聚果糖0.5-0.7份、低聚异麦芽糖0.3-0.5份、牛骨肽0.2-0.4份。
优选地，所述维生素包括维生素B1 0.04-0.06份、维生素B2 0.04-0.06份。
优选地，所述维生素包括维生素B1 0.05份、维生素B2 0.05份。
本品胃肠道功能紊乱患者需补充多种营养补充剂
胃肠道功能紊乱患者应补充优质易吸收的动植物蛋白
蛋白质-能量缺乏性营养不良是活动性炎性肠病突出的临床特征。累及小肠的病变比结肠病变更易引起营养不良和特殊营养元素的缺乏，CD病人慢性营养缺乏比UC病人更常见。临床常通过静脉高价营养疗法，从静脉补充大量的蛋白质和热卡，促使全胃肠道休息，达到正氮平衡和临床症状明显减轻。
牛骨胶原蛋白肽是一种富含多种必须氨基酸的小分子肽类，是一种优质的动物蛋白，其分子量可以做到1000Da以下，人体吸收利用度良好，尤其适于胃肠道失调患者使用。大豆肽粉作为优质的植物蛋白，可以缓解炎性肠病的症状，如结肠炎症和肠屏障功能丧失等；对人类肠道细胞也具有抗氧化和细胞保护作用。
多食新鲜蔬果有助于调节胃肠道功能
(1)南瓜
南瓜中含有胡萝卜素，具有抗氧化作用，并且可以直接抵抗致癌因子。在平时适当的吃南瓜可以帮助消除致癌物质亚硝酸胺突变，而且南瓜含有丰富的果胶，在一些品种的南瓜中可达2.03％，果胶可保护胃肠道不受粗糙食物刺激，促进溃疡愈合。南瓜粥有抑制胃酸分泌过多的功效，因而溃疡病患者食用南瓜粥尤为适宜。
南瓜中钾含量特别高，钾具有维持神经肌肉的应激性和正常功能作用，严重缺钾时，可影响胃肠道肌肉，出现肠麻痹和肠梗阻，钾有促进胃肠道蠕动作用。南瓜中含有丰富的果胶等膳食纤维，果胶虽不能被人体消化吸收，但能吸水膨胀，具有增加肠道内粪便体积、润滑肠道作用，能促进排便。南瓜中的膳食纤维还能被肠道中的微生物发酵，产生一些有机酸和气体而刺激肠道蠕动。南瓜可以促进排便、防止便秘，缩短粪便在肠道中的停留时间，并可减少肠道中有毒物质的产生和有毒物质在肠道中的存留，减少肠癌的发生。同时南瓜中丰富的果胶有助于保护消化道黏膜、促进消化道溃疡愈合作用。
(2)紫甘蓝
紫甘蓝又称红甘蓝、赤甘蓝，俗称紫包菜，十字花科、芸苔属甘蓝种中的一个变种，是结球甘蓝中的一个类型。紫甘蓝富含膳食纤维、维生素C、叶酸和维生素K等营养物质。研究人员探究了紫甘蓝经体外模拟消化前后相关抗氧化物质含量及其细胞抗氧化水平的变化，同时以Caco-2细胞为细胞模型，运用多种生物学技术与方法，深入研究了紫甘蓝对甜蜜素联合柠檬黄诱导细胞损伤的防护机制。紫甘蓝能够进一步激动NrG活化入核，激活Nrf2-ARE通路，主要对下游的HO-1解毒酶有较强的诱导作用，从而对甜蜜素联合柠檬黄诱导Caco-2细胞的损伤发挥了一定的预防作用。
(3)西红柿
西红柿富含多种维生素、有机酸、蛋白质、纤维素等物质，能起到刺激胃肠道消化液分泌、加速胃肠道蠕动的作用。《本草纲目》载：西红柿，健胃消食，治口渴、食欲不振。现代医学研究也表明，西红柿中的维生素C可软化血管，促进钙、铁元素吸收，对肠道粘膜有保护作用；西红柿所含纤维素可促进肠道腐败食物排泄，有助于预防肠癌；所含少量西红柿碱，能抑制多种细菌和致病真菌繁殖，助力维护良好的肠道内环境。
西班牙瓦伦西亚大学的一项研究结果发现，熟番茄酱中的番茄红素含量更高，在消化过程中更易被吸收。罗伊氏乳杆菌是一种具有改善过敏体质、预防过敏反复发作以及调节肠道功能的益生菌，在人体中自然存在。而熟番茄中的大量番茄红素可提高罗伊氏乳杆菌活性，促进其功效的发挥，进而保护肠道的健康。
(4)胡萝卜和白萝卜
胡萝卜又称红萝卜或甘荀，为伞形花科,一、二年生草本的根茎类蔬菜。萝卜汁和胡萝卜浆是常见的胡萝卜深加工产品，其加工附产物胡萝卜残渣富含膳食纤维，具有润肠通便功能的影响，可以通过增加粪便量和排便次数、以及通过促进肠道蠕动、缩短粪便通过肠道时间而改善肠道功能。
白萝卜又称莱菔、太根、菜头，为十字花科萝卜属一或二年生草本植物，白萝卜作为食物及药用植物应用久远，传统中医认为其味辛、甘、凉，具有消积滞、化痰热、下气、宽中、解毒的作用，可用于食积胀满、呃噎反胃等症。在胃肠动力方面，国外已有学者对白萝卜提取物刺激大鼠肠动力的生理机制及白萝卜叶提取物对豚鼠回、结肠刺激活动的药理学机制进行了研究，初步明确了其对胃肠动力的促进作用[9]。
白萝卜还含有一般蔬菜及水果不具备的莱菔甙，其与多种酶作用会产生异硫氰酸酯，可刺激肠胃蠕动。白萝卜中多样成分的组合，决定了其药理作用的复杂性。也有报道指出白萝卜中含有辛辣成分的芥子油，可促进胃肠蠕动，增食欲，助消化；芥子油还具有促进脂肪新陈代谢,可避免脂肪在皮下堆积的作用。
(5)苦瓜
苦瓜具有良好的排毒美容效果，性平，能够很好地消除身体的邪热以及疲乏情况。现代医学研究表明，苦瓜中含有人体所需要的大量营养素。比如胡萝卜素、蛋白质以及维生素等，经常食用苦瓜对身体健康很有帮助。食用苦瓜可以促进食欲、帮助消化，对多种胃肠道疾病、便秘还有内外痔疮也有很好的治疗效果。
(6)菠菜、芹菜、山芋、甜菜根等富含膳食纤维的蔬果
胃肠道失调的患者需做好饮食的调理，饮食宜食清淡好消化、营养丰富的食物，多吃新鲜的蔬菜和水果。富含膳食纤维的蔬果可以促进肠蠕动、减少食物在肠道中停留时间，促进益生菌生长，在保持消化系统健康上扮演着重要的角色，同时摄取足够的膳食纤维也可以预防心血管疾病、癌症、糖尿病以及其它疾病。菠菜、芹菜、山芋、甜菜根等多种蔬菜含有丰富的营养成分和膳食纤维，适合胃肠道失调的患者食用。其中，芹菜含有丰富的挥发性芳香油，既能增进食欲、促进血液循环，还能起到醒脑提神的食疗效用。菠菜富含类胡萝卜素、维生素C、维生素K、矿物质(钙质、铁质等)、辅酶Q10等多种营养素，可以通肠导便，防治痔疮，大量的植物粗纤维也可以促进肠道蠕动和胰腺分泌，帮助消化。
3.补充谷物膳食纤维可促进肠道蠕动，改善胃肠道功能
根据GB/Z 21922—2008《食品营养成分基本术语》的定义，膳食纤维(dietaryfiber)是指植物中天然存在的、提取或合成的碳水化合物的聚合物，其聚合度(degree ofpolymerization，DP)≥3，不能被人体小肠消化吸收、对人体有健康意义。除了蔬果，全谷物，包括藜麦、苦荞、薏米、青稞、玉米、小米、燕麦、糙米、黑米等也是膳食纤维的重要来源。建议在每天的主食中全谷物含量占三分之一左右。《中国居民膳食指南》(2016)对一般人群的膳食推荐一中提出，“食物多样，谷类为主”，每天建议摄入全谷物和杂豆50～150克。研究结果表明，谷物纤维能够增加排便次数、缩短肠道通过时间，对肠道运动具有促进作用，同时不增加胃肠道副反应[11]。
(1)燕麦
燕麦又称之为雀麦，是一种低糖、高营养、高能食品。燕麦中蛋白质含量十分丰富(15.6％)，是大米、小麦粉的1.6-2.3倍，在禾谷类粮食中居首位。燕麦蛋白营养价值很高，含有18种氨基酸，其中8种是人体必需氨基酸。8种必需氨基酸不仅含量丰富且配比合理，接近FAO/WHO推荐的营养模式，人体利用率高。燕麦兼具可溶性和不溶性两种膳食纤维，因而又被誉为天然膳食纤维家族中的“贵族”。燕麦总纤维素含量为17-21％，其中可溶性膳食纤维(主要成分是β-葡聚糖)约占总膳食纤维的1/3，明显高于其他谷物，可降低甘油三脂的低密度脂肪蛋白，促使胆固醇排泄，同时功能通便导泄，对于习惯性便秘患者有很好的帮助。
(2)青稞
青稞营养价值高，富含蛋白质、维生素、膳食纤维，并且含有较少的脂肪和糖类，是藏民补充营养的主要食物，也是维持藏民身体健康的重要元素来源之一。青稞含有β-葡聚糖、多酚类物质、黄酮类物质和麦绿素等对人体有益的功效成分，青稞提取物对于胃肠道健康具有一定的调节作用。Chen等从青稞中分离出β-葡聚糖，应用在大鼠胃溃疡模型中，发现β-葡聚糖治疗可减轻乙醇对胃的损伤和胃黏膜的损害，可能与β-葡聚糖抗氧化、抗炎机制有关；应用在小鼠肠道健康促进模型中，β-葡聚糖的处理增加了小鼠结肠及盲肠的结肠长度、含水量和总短链脂肪酸浓度，从而证明β-葡聚糖对实验室啮齿动物的胃肠道有保护作用。Chen等从青稞酒中分离出一株罗伊氏乳杆菌WHH1689，采用右旋糖酐硫酸钠诱导的小鼠模型评价其在体内的影响，结果表明：WHH1689菌株增加了小鼠粪便中双歧杆菌的存活数，对模拟胃肠道条件具有抵抗能力，并且可以在试验性结肠炎小鼠模型中有益地修饰肠道菌群；
四、药食同源中药用于调节胃肠道的现代医学研究
胃肠道失调多伴随反酸、嗳气、腹痛、腹泻、便秘等症状，反复发作。中医认为其根本内因均为脾胃受损，运化失司，水谷不化，清浊不分。茯苓、山药、芡实、莲子均为药食同用之物，药性平和，既能调和脾胃，又能止泻安神。其中，茯苓性平和，味甘淡，统归心肺脾肾经，益气健脾除湿，同时有利尿通淋之效，一方面实脾，一方面利小便实大便。方中的茯苓，山药，莲子，芡实为中医健脾名方，有四臣汤的传说，因为乾隆服用药方之后，效果立显，故就变成‘四神汤’了。方中山药的性味平甘，为《神农本草经》中的上品，取其补缓不骤，香微不燥，其归脾、肺、肾经，具有益肾气，健脾气，止泄痢，化痰润毛等功效，山药还可以与茯苓起健脾相协之功。芡实，归于脾肾经，性味平甘涩，首载于《神农本草经》，具有益肾固精、补脾止泻、除湿止带的疗效，临床广泛用于遗精滑精，遗尿尿频，脾虚久泻，白浊带下等疾病的治疗。莲子是莲的干燥成熟种子，营养价值高，具有“莲参”之称，性平，味甘涩，归于脾肾心经，具有健脾厚肠、益肾涩精、止带调经等功效。全方配伍，可以调理脾胃，补而不滞，温而不燥，对于胃肠道疾病具有很好的调养作用。
1.茯苓对胃肠道的改善作用
茯苓是多孔菌科真菌茯苓的干燥菌核；性味甘、淡，平，归心、肺、脾、肾经；利水渗湿、健脾，宁心，无毒，功效广泛，与适宜的药物配伍，不论寒、温、风、湿诸疾，均能发挥其独特功效。
脾胃湿热证是中医常见的证型，而胃黏膜AQP3、AQP4的异常表达可能是其发病机制之一。倪文娟等筛选了茯苓三萜类利水成分，发现去氢松香酸甲酯与AQP1、AQP4、AQP5结合的活性较强，其或许是茯苓治疗脾胃湿热症的关键活性成分。张兵影等探讨茯苓水煎液、茯苓总三萜及茯苓多糖对饮食失节、过食肥甘所致的脾虚小鼠的作用，发现茯苓总三萜对脾虚小鼠具有明显的恢复作用。经研究表明，茯苓水煎液对脾气虚腹泻大鼠的小肠推进具有抑制作用，茯苓粗提物能抑制家兔离体空肠和盲肠平滑肌收缩运动，使收缩张力和舒张张力减弱，收缩振幅减小，其剂量越大作用越强，并呈量效关系。Xu等研究证明16α-羟基松苓酸能够改善肿瘤坏死因子-α(TNF-α)诱导的结肠腺癌细胞Caco-2单层肠上皮屏障损伤，并抑制磷脂酰肌醇-3激酶(PI3K)和蛋白激酶B(Akt)的激活，从而通过激活糖皮质激素受体(GR)以减弱下游核转录因子-κB抑制蛋白(IκB)和核因子-κB(NF-κB)磷酸化，改善肠屏障功能。
研究也发现，茯苓对健康小鼠腹膜孔的调控作用不明显。茯苓的水煎液能直接松弛家兔离体肠肌、减小肠肌收缩振幅；能防治大鼠实验性胃溃疡，抑制胃液分泌。研究表明，茯苓三萜及其衍生物可抑制无水硫酸铜引起的呕吐。茯苓醇提液及其17种三萜类成分的镇吐作用显示，侧链上的C-24位含有末端双键基团的三萜具有极好的止吐作用。茯苓多糖的代谢主要在肠道中进行。
2.山药对胃肠道的调节作用
山药为薯蓣科植物薯蓣的干燥根茎，具有补脾养胃、生津益肺、补肾涩精的功效。现代研究表明山药主要化学成分包括多糖、氨基酸、脂肪酸、山药素类化合物、尿囊素、微量元素、淀粉等。具有降血糖、降血脂、抗氧化、调节脾胃、抗肿瘤、免疫调节等药理作用。山药在胃肠道运化方面具有显著作用，有动物实验表明麸炒山药水提液中的二氯甲烷萃取物可以抑制小鼠的胃排空，其中二氯甲烷和正丁醇萃取物可以有效制止肠道的推进作用。傅紫琴等通过观察山药多糖对脾虚小鼠的影响，发现其能抑制胃肠排空，提高胸腺及脾脏指数，初步推断其提高免疫力是其补脾的关键之一。
山药具有抗炎、扶正固本、增强免疫的作用，可将其作为益生元制剂使用。从基因水平验证纳米山药多糖结肠靶向制剂具有扶植优势菌群如双歧杆菌的生长，从而抑制大肠杆菌等致病菌群生产的作用，增加肠道菌群丰富度，提高菌群总DNA数量，改善肠道菌群环境，有助于菌群失调的治疗。中药微生态调节剂具有调节微生态失调、保持微生态平衡的作用。山药多糖具有调节肠道微生态的作用。谭春爱等应用纳米山药多糖对SD大鼠的研究表明，功能性多糖具有促进肠道有益菌生长、抑制有害菌繁殖的作用。纳米山药多糖合生元结肠靶向微生态调节剂具有调节优势菌厚壁菌门的作用，使优势菌群数量增加。从纲的水平上看，纳米山药多糖合生元结肠靶向微生态调节剂使优势菌纲梭菌纲的数量增加，并且使芽孢杆菌纲和产芽孢菌纲的数量也增加，成为优势菌。
纳米山药多糖合生元结肠靶向胶囊通过调整肠道菌群失调，使肠道有益菌占优势，改善肠道屏障。肠道是人体内最大的细菌存储库，胃肠粘膜是最敏感的，当肠粘膜受损，肠道内细菌易位，甚至引起内毒血症,加速了危重病的发展。目前，已经证实内毒血症是肝衰竭继发多脏器衰竭的使动因素。因此，重视胃肠功能在肝衰竭的发展中的作用，早起防治肠道功能障碍对缓解肝衰竭病情，阻止其发展，降低死亡率具有十分重要的作用。有研究发现，灌胃较高剂量的山药多糖不仅能使小鼠的体重发生明显变化，而且对小鼠盲结肠内的微生物有显著影响，在抑制条件致病菌的同时，显著提高了益生菌的增殖。
与现有技术相比，本发明具有如下的有益效果：
本发明芡实，归于脾肾经，性味平甘涩，首载于《神农本草经》，具有益肾固精、补脾止泻、除湿止带的疗效，临床广泛用于遗精滑精，遗尿尿频，脾虚久泻，白浊带下等疾病的治疗。李湘利等的实验证实芡实多糖能够抑制细菌生长，而且对于金黄色葡萄球菌抑菌最强。於怀龙等的研究表明芡实原料的醇、水提取物合并后可以降低小鼠急性胃黏膜损伤和胃溃疡指数，为临床芡实在治疗急性黏膜损伤的应用提供新方向。
具体实施方式
下面结合具体实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
本实施例的一种适用肠胃患者多维营养素配方，包括以下重量份原料：
山药0.1-0.3份、苦荞0.1-0.3份、莲子0.17-0.19份、基础包0.1-0.2份、芡实0.17-0.19份、薏苡仁0.06-0.08份、菊苣1-2份、茯苓0.1-0.3份、圆白菜0.11-0.13份、胡萝卜0.11-0.13份、西红柿0.11-0.13份、紫甘蓝0.05-0.07份、南瓜0.11-0.13份、芹菜0.05-0.07份、甜菜根0.05-0.07份、白萝卜0.03-0.05份、黄瓜0.11-0.13份、苦瓜0.05-0.07份、菠菜0.11-0.13份、营养包0.5-0.7份、赤藓糖醇0.1-0.3份、木糖醇0.1-0.3份、甜菊糖苷0.002-0.004份、维生素0.04-0.06份、叶酸14-16份。
本实施例的适用肠胃患者多维营养素配方包括以下重量份原料：
山药0.2-0.3份、苦荞0.2-0.3份、莲子0.18-0.19份、基础包0.12-0.2份、芡实0.18-0.19份、薏苡仁0.07-0.08份、菊苣1.1-2份、茯苓0.2-0.3份、圆白菜0.12-0.13份、胡萝卜0.12-0.13份、西红柿0.12-0.13份、紫甘蓝0.06-0.07份、南瓜0.12-0.13份、芹菜0.06-0.07份、甜菜根0.06-0.07份、白萝卜0.04-0.05份、黄瓜0.12-0.13份、苦瓜0.06-0.07份、菠菜0.12-0.13份、营养包0.6-0.7份、赤藓糖醇0.2-0.3份、木糖醇0.2-0.3份、甜菊糖苷0.003-0.004份、维生素0.05-0.06份、叶酸15-16份。
本实施例的适用肠胃患者多维营养素配方包括以下重量份原料：
山药0.2份、苦荞0.2份、莲子0.18份、基础包0.15份、芡实0.18份、薏苡仁0.07份、菊苣1.5份、茯苓0.2份、圆白菜0.12份、胡萝卜0.12份、西红柿0.12份、紫甘蓝0.06份、南瓜0.12份、芹菜0.06份、甜菜根0.06份、白萝卜0.04份、黄瓜0.12份、苦瓜0.06份、菠菜0.12份、营养包0.6份、赤藓糖醇0.2份、木糖醇0.25份、甜菊糖苷0.003份、维生素0.05份、叶酸15份。
本实施例的基础包为青稞0.06-0.08份、燕麦0.06-0.08份、黑米0.05-0.07份、糙米0.06-0.008份、山芋0.1-0.3份。
本实施例的基础包为青稞0.07份、燕麦0.07份、黑米0.06份、糙米0.07份、山芋0.2份。
本实施例的营养包为低聚果糖0.5-0.7份、低聚异麦芽糖0.3-0.5份、牛骨肽0.2-0.4份。
本实施例的维生素包括维生素B1 0.04-0.06份、维生素B2 0.04-0.06份。
本实施例的维生素包括维生素B1 0.05份、维生素B2 0.05份。
实施例1：
本实施例的一种适用肠胃患者多维营养素配方，包括以下重量份原料：
山药0.2份、苦荞0.2份、莲子0.18份、基础包0.15份、芡实0.18份、薏苡仁0.07份、菊苣1.5份、茯苓0.2份、圆白菜0.12份、胡萝卜0.12份、西红柿0.12份、紫甘蓝0.06份、南瓜0.12份、芹菜0.06份、甜菜根0.06份、白萝卜0.04份、黄瓜0.12份、苦瓜0.06份、菠菜0.12份、营养包0.6份、赤藓糖醇0.2份、木糖醇0.25份、甜菊糖苷0.003份、维生素0.05份、叶酸15份。
本实施例的基础包为青稞0.06份、燕麦0.06份、黑米0.05份、糙米0.06份、山芋0.1份、
本实施例的营养包为低聚果糖0.5份、低聚异麦芽糖0.3份、牛骨肽0.2份。
本实施例的维生素包括维生素B1 0.04份、维生素B2 0.04份。
实施例2：
本实施例的一种适用肠胃患者多维营养素配方，包括以下重量份原料：
山药0.2份、苦荞0.2份、莲子0.18份、基础包0.15份、芡实0.18份、薏苡仁0.07份、菊苣1.5份、茯苓0.2份、圆白菜0.12份、胡萝卜0.12份、西红柿0.12份、紫甘蓝0.06份、南瓜0.12份、芹菜0.06份、甜菜根0.06份、白萝卜0.04份、黄瓜0.12份、苦瓜0.06份、菠菜0.12份、营养包0.6份、赤藓糖醇0.2份、木糖醇0.25份、甜菊糖苷0.003份、维生素0.05份、叶酸15份。
本实施例的基础包为青稞0.07份、燕麦0.07份、黑米0.06份、糙米0.07份、山芋0.2份。
本实施例的维生素包括维生素B1 0.05份、维生素B2 0.05份。
对于本领域技术人员而言，显然本发明不限于上述示范性实施例的细节，而且在不背离本发明的精神或基本特征的情况下，能够以其他的具体形式实现本发明。因此，无论从哪一点来看，均应将实施例看作是示范性的，而且是非限制性的，本发明的范围由所附权利要求而不是上述说明限定，因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。
此外，应当理解，虽然本说明书按照实施方式加以描述，但并非每个实施方式仅包含一个独立的技术方案，说明书的这种叙述方式仅仅是为清楚起见，本领域技术人员应当将说明书作为一个整体，各实施例中的技术方案也可以经适当组合，形成本领域技术人员可以理解的其他实施方式。
Claims (8)
1.一种适用肠胃患者多维营养素配方，其特征在于，包括以下重量份原料：
山药0.1-0.3份、苦荞0.1-0.3份、莲子0.17-0.19份、基础包0.1-0.2份、芡实0.17-0.19份、薏苡仁0.06-0.08份、菊苣1-2份、茯苓0.1-0.3份、圆白菜0.11-0.13份、胡萝卜0.11-0.13份、西红柿0.11-0.13份、紫甘蓝0.05-0.07份、南瓜0.11-0.13份、芹菜0.05-0.07份、甜菜根0.05-0.07份、白萝卜0.03-0.05份、黄瓜0.11-0.13份、苦瓜0.05-0.07份、菠菜0.11-0.13份、营养包0.5-0.7份、赤藓糖醇0.1-0.3份、木糖醇0.1-0.3份、甜菊糖苷0.002-0.004份、维生素0.04-0.06份、叶酸14-16份。
2.根据权利要求1所述的一种适用肠胃患者多维营养素配方，其特征在于，所述适用肠胃患者多维营养素配方包括以下重量份原料：
山药0.2-0.3份、苦荞0.2-0.3份、莲子0.18-0.19份、基础包0.12-0.2份、芡实0.18-0.19份、薏苡仁0.07-0.08份、菊苣1.1-2份、茯苓0.2-0.3份、圆白菜0.12-0.13份、胡萝卜0.12-0.13份、西红柿0.12-0.13份、紫甘蓝0.06-0.07份、南瓜0.12-0.13份、芹菜0.06-0.07份、甜菜根0.06-0.07份、白萝卜0.04-0.05份、黄瓜0.12-0.13份、苦瓜0.06-0.07份、菠菜0.12-0.13份、营养包0.6-0.7份、赤藓糖醇0.2-0.3份、木糖醇0.2-0.3份、甜菊糖苷0.003-0.004份、维生素0.05-0.06份、叶酸15-16份。
3.根据权利要求1所述的一种适用肠胃患者多维营养素配方，其特征在于，所述适用肠胃患者多维营养素配方包括以下重量份原料：
山药0.2份、苦荞0.2份、莲子0.18份、基础包0.15份、芡实0.18份、薏苡仁0.07份、菊苣1.5份、茯苓0.2份、圆白菜0.12份、胡萝卜0.12份、西红柿0.12份、紫甘蓝0.06份、南瓜0.12份、芹菜0.06份、甜菜根0.06份、白萝卜0.04份、黄瓜0.12份、苦瓜0.06份、菠菜0.12份、营养包0.6份、赤藓糖醇0.2份、木糖醇0.25份、甜菊糖苷0.003份、维生素0.05份、叶酸15份。
4.根据权利要求1所述的一种适用肠胃患者多维营养素配方，所述基础包为青稞0.06-0.08份、燕麦0.06-0.08份、黑米0.05-0.07份、糙米0.06-0.008份、山芋0.1-0.3份。
5.根据权利要求4所述的一种适用肠胃患者多维营养素配方，其特征在于，所述基础包为青稞0.07份、燕麦0.07份、黑米0.06份、糙米0.07份、山芋0.2份。
6.根据权利要求1所述的一种适用肠胃患者多维营养素配方，其特征在于，所述营养包为低聚果糖0.5-0.7份、低聚异麦芽糖0.3-0.5份、牛骨肽0.2-0.4份。
7.根据权利要求1所述的一种适用肠胃患者多维营养素配方，其特征在于，所述维生素包括维生素B1 0.04-0.06份、维生素B2 0.04-0.06份。
8.根据权利要求7所述的一种适用肠胃患者多维营养素配方，其特征在于，所述维生素包括维生素B1 0.05份、维生素B2 0.05份。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210295642.3A CN114711402A (zh) | 2022-03-24 | 2022-03-24 | 一种适用肠胃患者多维营养素配方 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210295642.3A CN114711402A (zh) | 2022-03-24 | 2022-03-24 | 一种适用肠胃患者多维营养素配方 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114711402A true CN114711402A (zh) | 2022-07-08 |
Family
ID=82239321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210295642.3A Pending CN114711402A (zh) | 2022-03-24 | 2022-03-24 | 一种适用肠胃患者多维营养素配方 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114711402A (zh) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104187611A (zh) * | 2014-07-26 | 2014-12-10 | 胡安然 | 胃肠道吸收障碍全营养配方食品 |
| CN106262869A (zh) * | 2016-09-06 | 2017-01-04 | 湖南益百年健康科技有限公司 | 有益中老年人补充钙质、润养肠胃的营养早餐及制备方法 |
| CN107874251A (zh) * | 2017-11-14 | 2018-04-06 | 广东健来福云健康科技股份有限公司 | 一种具有健脾胃益肠道功能的八珍益生菌组合物 |
| CN110037294A (zh) * | 2019-04-12 | 2019-07-23 | 吉林省九圣源生物科技有限公司 | 一种供胃及肠道溃疡疾病人群食用的药膳 |
-
2022
- 2022-03-24 CN CN202210295642.3A patent/CN114711402A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104187611A (zh) * | 2014-07-26 | 2014-12-10 | 胡安然 | 胃肠道吸收障碍全营养配方食品 |
| CN106262869A (zh) * | 2016-09-06 | 2017-01-04 | 湖南益百年健康科技有限公司 | 有益中老年人补充钙质、润养肠胃的营养早餐及制备方法 |
| CN107874251A (zh) * | 2017-11-14 | 2018-04-06 | 广东健来福云健康科技股份有限公司 | 一种具有健脾胃益肠道功能的八珍益生菌组合物 |
| CN110037294A (zh) * | 2019-04-12 | 2019-07-23 | 吉林省九圣源生物科技有限公司 | 一种供胃及肠道溃疡疾病人群食用的药膳 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101564161B (zh) | 高血脂高血糖患者专用的营养保健食品及其制备方法 | |
| CN104432084B (zh) | 一种调理粉及其制备方法和用途 | |
| CN101606704B (zh) | 一种具有多种功能作用的膳食纤维食品 | |
| CN109123643A (zh) | 一种谷物代餐球的制备方法 | |
| CN110771880A (zh) | 一种降糖藜麦代餐粉及其制备工艺 | |
| CN108523138A (zh) | 一种降血糖代餐粉 | |
| CN103463457B (zh) | 铁皮石斛猴头菇复配咀嚼片及其制备方法 | |
| CN104856003A (zh) | 糖尿病非全营养配方食品 | |
| CN106605923A (zh) | 一种复合膳食纤维及其制备方法 | |
| CN108719984B (zh) | 一种针对痛风人群的代餐营养棒及其制备方法 | |
| CN102125212B (zh) | 一种保健减肥产品及其制备方法 | |
| CN109966417A (zh) | 一种针对糖尿病人群的固体饮料 | |
| CN104643250A (zh) | 一种可双向调节体重改善亚健康的固体饮料 | |
| CN108887564A (zh) | 一种硒蛋白杂粮粉配方及其制备方法 | |
| KR100716123B1 (ko) | 마 또는 산약의 유산 발효액을 함유하는 변비 및 비만의예방 및 개선용 식품 조성물 | |
| CN111227260A (zh) | 一种富含膳食纤维的组合物、谷膳餐包固体饮料及其制备方法 | |
| CN106418501A (zh) | 一种具有减肥功能的保健食品 | |
| CN111280280A (zh) | 一种低糖减肥咖啡及制备方法 | |
| KR100707707B1 (ko) | 마 또는 산약의 유산 발효액을 함유하는 변비 예방 및개선용 건강기능식품 | |
| CN110051815A (zh) | 一种辅助降血糖食丸及其制备方法 | |
| CN105613882A (zh) | 黑青稞降糖茶（奶茶） | |
| CN110574862A (zh) | 一种适用于青少年儿童的营养减肥代餐粉及其制备方法 | |
| CN103005264B (zh) | 一种含有壳寡糖的保健食品及其制备方法 | |
| CN110638038A (zh) | 一种用于控制高血糖的医学配方营养代餐粉及其制备方法 | |
| CN114711402A (zh) | 一种适用肠胃患者多维营养素配方 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |