CN1138532C - 药用气溶胶组合物 - Google Patents

药用气溶胶组合物 Download PDF

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Publication number
CN1138532C
CN1138532C CNB988008300A CN98800830A CN1138532C CN 1138532 C CN1138532 C CN 1138532C CN B988008300 A CNB988008300 A CN B988008300A CN 98800830 A CN98800830 A CN 98800830A CN 1138532 C CN1138532 C CN 1138532C
Authority
CN
China
Prior art keywords
composition
low volatility
aerosol
mmad
hfa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB988008300A
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English (en)
Chinese (zh)
Other versions
CN1229355A (zh
Inventor
D��������
D·莱维斯
D·甘德堂
B·米金
P·温图拉
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G·布拉姆比拉
R·加尔兹亚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10814179&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1138532(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of CN1229355A publication Critical patent/CN1229355A/zh
Application granted granted Critical
Publication of CN1138532C publication Critical patent/CN1138532C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB988008300A 1997-06-13 1998-06-10 药用气溶胶组合物 Expired - Lifetime CN1138532C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9712434.1 1997-06-13
GB9712434A GB2326334A (en) 1997-06-13 1997-06-13 Pharmaceutical aerosol compositions

Publications (2)

Publication Number Publication Date
CN1229355A CN1229355A (zh) 1999-09-22
CN1138532C true CN1138532C (zh) 2004-02-18

Family

ID=10814179

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988008300A Expired - Lifetime CN1138532C (zh) 1997-06-13 1998-06-10 药用气溶胶组合物

Country Status (44)

Country Link
EP (2) EP0920302B2 (enExample)
JP (1) JP4380802B2 (enExample)
KR (1) KR100546239B1 (enExample)
CN (1) CN1138532C (enExample)
AR (1) AR012977A1 (enExample)
AT (1) ATE222751T1 (enExample)
AU (1) AU729966B2 (enExample)
BG (1) BG63906B1 (enExample)
BR (1) BR9805993B1 (enExample)
CA (1) CA2263445C (enExample)
CO (1) CO4940408A1 (enExample)
CZ (1) CZ295521B6 (enExample)
DE (1) DE69807420T3 (enExample)
DK (1) DK0920302T4 (enExample)
DZ (1) DZ2516A1 (enExample)
EA (1) EA001259B1 (enExample)
EE (1) EE03664B1 (enExample)
ES (1) ES2182351T5 (enExample)
GB (1) GB2326334A (enExample)
GE (1) GEP20012462B (enExample)
HR (1) HRP980317B1 (enExample)
HU (1) HU228487B1 (enExample)
ID (1) ID21491A (enExample)
IL (1) IL128484A (enExample)
IN (1) IN189317B (enExample)
IS (1) IS2435B (enExample)
IT (1) IT1293803B1 (enExample)
MA (1) MA26507A1 (enExample)
ME (2) ME00333B (enExample)
MY (1) MY119074A (enExample)
NO (1) NO327775B1 (enExample)
NZ (1) NZ334149A (enExample)
PL (1) PL193721B1 (enExample)
PT (1) PT920302E (enExample)
RS (1) RS51274B (enExample)
SA (1) SA98190821B1 (enExample)
SI (1) SI0920302T2 (enExample)
SK (1) SK284430B6 (enExample)
TN (1) TNSN98087A1 (enExample)
TR (1) TR199900288T1 (enExample)
TW (1) TW555570B (enExample)
UA (1) UA70289C2 (enExample)
WO (1) WO1998056349A1 (enExample)
ZA (1) ZA985136B (enExample)

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IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
ES2274803T3 (es) 1999-09-11 2007-06-01 Glaxo Group Limited Formulacion farmaceutica de propionato de fluticasona.
EP1231894B1 (en) * 1999-11-23 2005-01-12 Glaxo Group Limited Pharmaceutical formulations of salmeterol
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IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
UA73986C2 (uk) * 2000-05-22 2005-10-17 К'Єзі Фармачеутічі С.П.А. АЕРОЗОЛЬНА КОМПОЗИЦІЯ, ЩО МІСТИТЬ <font face="Symbol">b</font>2-АДРЕНЕРГІЧНИЙ АГОНІСТ ТРИВАЛОЇ ДІЇ, ДОЗУЮЧИЙ ІНГАЛЯТОР ПІД ТИСКОМ ТА СПОСІБ ЙОГО ЗАПОВНЕННЯ
WO2002072067A2 (en) * 2001-03-12 2002-09-19 Glaxo Group Limited Pharmaceutical aerosol formulation
ES2222294T3 (es) 2001-07-02 2005-02-01 Chiesi Farmaceutici S.P.A. Formulacion optimizada de tobramicina para administracion en forma de aerosol.
EP3384931B1 (en) 2002-03-01 2019-07-24 Chiesi Farmaceutici S.p.A. Formoterol superfine formulation
EP1340503A1 (en) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Solution aerosol formulation containing esters of 3, 17-dihydroxy oestratriene derivates for pulmonary delivery
EP1340492A1 (en) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Aerosol formulations for pulmonary administration of medicaments having systemic effects
DE10214263A1 (de) * 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
EP1369113B1 (en) * 2002-06-06 2006-11-22 CHIESI FARMACEUTICI S.p.A. Solubilisation of drugs in HFA propellant by means of emulsions
AU2003293528A1 (en) * 2003-02-04 2004-09-06 Chrysalis Technologies Incorporated Perfluorocarbon and hydrofluorocarbon formulations and methods of making and using same
EP1915985A1 (en) 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants
ES2304616T3 (es) * 2003-03-20 2008-10-16 Boehringer Ingelheim Pharmaceuticals Inc. Formulacion para un inhalador con dosis medida utilizando hidro-fluoro-alcanos como propulsores.
SE0303179D0 (sv) * 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
EA013428B1 (ru) 2004-07-02 2010-04-30 Бёрингер Ингельхайм Интернациональ Гмбх РАСПЫЛЯЕМЫЕ В ВИДЕ АЭРОЗОЛЯ СУСПЕНЗИОННЫЕ КОМПОЗИЦИИ С TG 227ea ИЛИ TG 134a В КАЧЕСТВЕ ПРОПЕЛЛЕНТА
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
GB0621707D0 (en) * 2006-10-31 2006-12-13 Univ London Pharmacy Formulations for delivery via pressurised metered dose inhalers
GB0712454D0 (en) 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions
CA2704639A1 (en) * 2007-11-07 2009-05-14 Astrazeneca Ab Dry powder formulations comprising ascorbic acid derivates
RU2561833C2 (ru) * 2010-09-06 2015-09-10 Кьези Фармасьютичи С.П.А. Дозирующий ингалятор и способ его применения
JP5409594B2 (ja) * 2010-12-22 2014-02-05 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧式定量吸入器のための安定な製薬学的溶液製剤
JP6335798B2 (ja) 2012-02-28 2018-05-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規噴射剤含有チオトロピウム製剤
RU2504402C1 (ru) * 2012-11-20 2014-01-20 Шолекс Девелопмент Гмбх Ингаляционный состав в форме аэрозоля для лечения бронхиальной астмы и хронической обструктивной болезни легких
GB201402513D0 (en) 2014-02-13 2014-04-02 Cardiff Scintigraphics Ltd Pressurised metered dose inhalers and method of manufacture
EP3174522A1 (en) 2014-07-29 2017-06-07 3M Innovative Properties Company Method of preparing a pharmaceutical composition
MA43782A (fr) 2016-03-31 2021-04-28 Chiesi Farm Spa Dispositif d'inhalation d'aérosol
PH12019500577B1 (en) * 2016-09-19 2023-09-08 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2025039045A1 (en) * 2023-08-23 2025-02-27 Inhaler Supplies Pty Ltd Inhalable formulation for volatile actives

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ES2038696T3 (es) † 1986-03-10 1996-07-16 Burghart Kurt Procedimiento para producir un preparado farmaceutico.
DE3767615D1 (de) † 1986-03-10 1991-02-28 Kurt Burghart Pharmazeutikum sowie verfahren zu seiner herstellung.
US4899874A (en) † 1988-04-26 1990-02-13 Rehrig-Pacific Company, Inc. Stackable low depth bottle case
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) † 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
EP0553298B1 (en) † 1990-10-18 1994-11-17 Minnesota Mining And Manufacturing Company Aerosol formulation comprising beclomethasone 17,21 dipropionate
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
ATE339952T1 (de) * 1991-06-10 2006-10-15 Schering Corp Fluorchlorkohlenwasserstofffreie aerosolformulierungen
DK0656206T3 (da) † 1991-06-10 2001-10-08 Schering Corp Aerosolformuleringer uden chlorfluorcarbonforbindelser
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
DE4123668A1 (de) * 1991-07-17 1993-01-21 Rovema Gmbh Verfahren und vorrichtung zur zufuehrung von folienmaterial zu einer intermittierend arbeitenden schlauchbeutelmaschine
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Also Published As

Publication number Publication date
NO327775B1 (no) 2009-09-21
DE69807420T3 (de) 2006-11-16
MEP44008A (en) 2011-02-10
IL128484A (en) 2004-09-27
PL331531A1 (en) 1999-07-19
DE69807420D1 (de) 2002-10-02
ES2182351T3 (es) 2003-03-01
EP1219293A3 (en) 2003-05-28
AU729966B2 (en) 2001-02-15
CA2263445A1 (en) 1998-12-17
RS51274B (sr) 2010-12-31
GB2326334A (en) 1998-12-23
EP1219293A2 (en) 2002-07-03
EE9900055A (et) 1999-08-16
YU6999A (sh) 2000-03-21
HK1022271A1 (en) 2000-08-04
BR9805993B1 (pt) 2009-05-05
MY119074A (en) 2005-03-31
NO990594D0 (no) 1999-02-09
EP0920302A1 (en) 1999-06-09
NO990594L (no) 1999-04-13
EP0920302B2 (en) 2006-06-21
BG63906B1 (bg) 2003-06-30
HUP0001339A3 (en) 2000-10-30
BR9805993A (pt) 1999-08-31
HRP980317B1 (en) 2002-06-30
KR100546239B1 (ko) 2006-01-26
AU8626298A (en) 1998-12-30
CN1229355A (zh) 1999-09-22
CO4940408A1 (es) 2000-07-24
SA98190821B1 (ar) 2006-11-19
DZ2516A1 (fr) 2004-11-08
GB9712434D0 (en) 1997-08-13
HRP980317A2 (en) 1999-04-30
ZA985136B (en) 1999-01-07
JP4380802B2 (ja) 2009-12-09
DK0920302T3 (da) 2002-12-23
GEP20012462B (en) 2001-06-25
TW555570B (en) 2003-10-01
EP0920302B1 (en) 2002-08-28
EA199900201A1 (ru) 1999-06-24
WO1998056349A1 (en) 1998-12-17
EA001259B1 (ru) 2000-12-25
SK17699A3 (en) 1999-07-12
IS2435B (is) 2008-10-15
ATE222751T1 (de) 2002-09-15
SI0920302T1 (en) 2002-12-31
ES2182351T5 (es) 2007-03-16
PL193721B1 (pl) 2007-03-30
MA26507A1 (fr) 2004-12-20
UA70289C2 (uk) 2004-10-15
DK0920302T4 (da) 2006-10-09
IN189317B (enExample) 2003-02-08
BG103221A (en) 1999-09-30
SI0920302T2 (sl) 2006-10-31
CA2263445C (en) 2008-09-09
CZ46299A3 (cs) 1999-07-14
PT920302E (pt) 2002-11-29
CZ295521B6 (cs) 2005-08-17
HUP0001339A2 (hu) 2000-09-28
ID21491A (id) 1999-06-17
IT1293803B1 (it) 1999-03-10
SK284430B6 (sk) 2005-04-01
TNSN98087A1 (fr) 2005-03-15
TR199900288T1 (xx) 1999-09-21
AR012977A1 (es) 2000-11-22
IS4974A (is) 1999-02-11
KR20000068171A (ko) 2000-11-25
JP2000516965A (ja) 2000-12-19
DE69807420T2 (de) 2003-05-08
ITMI971798A1 (it) 1999-01-28
NZ334149A (en) 2000-07-28
ME00333B (me) 2011-02-10
EE03664B1 (et) 2002-04-15
IL128484A0 (en) 2000-01-31
HU228487B1 (en) 2013-03-28

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