CN113150112B - 抗人乳头瘤病毒16 e7的t细胞受体 - Google Patents
抗人乳头瘤病毒16 e7的t细胞受体 Download PDFInfo
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- CN113150112B CN113150112B CN202110399056.9A CN202110399056A CN113150112B CN 113150112 B CN113150112 B CN 113150112B CN 202110399056 A CN202110399056 A CN 202110399056A CN 113150112 B CN113150112 B CN 113150112B
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- G—PHYSICS
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Zoology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
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- Microbiology (AREA)
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- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110399056.9A CN113150112B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004335P | 2014-05-29 | 2014-05-29 | |
| US62/004,335 | 2014-05-29 | ||
| CN201580031789.XA CN106661098B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
| CN202110399056.9A CN113150112B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
| PCT/US2015/033129 WO2015184228A1 (en) | 2014-05-29 | 2015-05-29 | Anti-human papillomavirus 16 e7 t cell receptors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580031789.XA Division CN106661098B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113150112A CN113150112A (zh) | 2021-07-23 |
| CN113150112B true CN113150112B (zh) | 2024-02-06 |
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ID=53396593
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110399056.9A Active CN113150112B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
| CN201580031789.XA Active CN106661098B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580031789.XA Active CN106661098B (zh) | 2014-05-29 | 2015-05-29 | 抗人乳头瘤病毒16 e7的t细胞受体 |
Country Status (21)
| Country | Link |
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| US (4) | US10174098B2 (enExample) |
| EP (3) | EP3689900B1 (enExample) |
| JP (5) | JP6742991B2 (enExample) |
| KR (2) | KR102445667B1 (enExample) |
| CN (2) | CN113150112B (enExample) |
| AU (5) | AU2015266818B2 (enExample) |
| BR (1) | BR112016027805A2 (enExample) |
| CA (1) | CA2950192A1 (enExample) |
| CY (1) | CY1122790T1 (enExample) |
| DK (1) | DK3149031T3 (enExample) |
| ES (1) | ES2784237T3 (enExample) |
| HR (1) | HRP20200376T1 (enExample) |
| IL (3) | IL290655B2 (enExample) |
| LT (1) | LT3149031T (enExample) |
| MX (2) | MX375379B (enExample) |
| PL (1) | PL3149031T3 (enExample) |
| PT (1) | PT3149031T (enExample) |
| SA (1) | SA516380394B1 (enExample) |
| SI (1) | SI3149031T1 (enExample) |
| SM (1) | SMT202000143T1 (enExample) |
| WO (1) | WO2015184228A1 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015184228A1 (en) * | 2014-05-29 | 2015-12-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-human papillomavirus 16 e7 t cell receptors |
| AU2016258845B2 (en) | 2015-05-01 | 2022-03-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
| AU2016363025B2 (en) | 2015-12-03 | 2021-04-08 | Juno Therapeutics, Inc. | Modified chimeric receptors and related compositions and methods |
| US10975436B2 (en) | 2016-01-05 | 2021-04-13 | Diamir, Llc | Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders |
| WO2017139199A1 (en) | 2016-02-10 | 2017-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inducible arginase |
| JP7730008B2 (ja) | 2016-09-27 | 2025-08-27 | セロ・セラピューティクス・ホールディングス・インコーポレイテッド | キメラエンガルフメント受容体分子 |
| WO2018067618A1 (en) * | 2016-10-03 | 2018-04-12 | Juno Therapeutics, Inc. | Hpv-specific binding molecules |
| BR112019011277A2 (pt) * | 2016-12-02 | 2019-10-22 | University Of Southern California | polinucleotídeo, sistema de expressão recombinante, vetor, polipeptídeo, célula recombinante, polipeptídeo de receptor imune sintético isolado ou heterodímero de polipeptídeo, célula efetora imune ou célula-tronco, população de células imunes ou efetoras, métodos de fabricação de uma célula efetora imune que expressa sir, de geração de uma população de células modificadas por rna, de fornecimento de imunidade antidoença e de tratamento ou prevenção de uma doença, composição, uso ou método, kit, e, sequência de aminoácidos. |
| GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
| US11980640B2 (en) * | 2017-05-15 | 2024-05-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Bicistronic chimeric antigen receptors and their uses |
| CA3066779A1 (en) * | 2017-06-28 | 2019-01-03 | Regeneron Pharmaceuticals, Inc. | Anti-human papillomavirus (hpv) antigen-binding proteins and methods of use thereof |
| MX2020007266A (es) | 2017-09-26 | 2020-09-07 | Cero Therapeutics Inc | Moleculas del receptor quimerico de engullido y metodos de uso. |
| FI3688027T3 (fi) | 2017-09-29 | 2025-12-09 | Us Health | Mutatoidun p53:n tunnistavia t-solureseptoreita |
| US11952408B2 (en) | 2017-10-03 | 2024-04-09 | Juno Therapeutics, Inc. | HPV-specific binding molecules |
| FI3692140T3 (fi) * | 2017-10-05 | 2023-10-11 | Us Health | Menetelmiä solujen laajentamiseksi selektiivisesti ekspressoiden TCR:ää vakiolla muriinialueella |
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| WO2019139987A1 (en) | 2018-01-09 | 2019-07-18 | Elstar Therapeutics, Inc. | Calreticulin binding constructs and engineered t cells for the treatment of diseases |
| CN118374524A (zh) | 2018-02-09 | 2024-07-23 | 美国卫生和人力服务部 | 拴系白细胞介素-15和白细胞介素-21 |
| JP7549533B2 (ja) * | 2018-03-28 | 2024-09-11 | セロ・セラピューティクス・インコーポレイテッド | キメラ貪食受容体のための発現ベクター、遺伝子改変宿主細胞およびそれらの使用 |
| US12291557B2 (en) | 2018-03-28 | 2025-05-06 | Cero Therapeutics Holdings, Inc. | Chimeric TIM4 receptors and uses thereof |
| EP3774865A1 (en) | 2018-03-28 | 2021-02-17 | Cero Therapeutics, Inc. | Cellular immunotherapy compositions and uses thereof |
| BR112020019313A2 (pt) * | 2018-04-05 | 2021-01-05 | Juno Therapeutics Inc | Receptores de células t e células modificadas que expressam os mesmos |
| CA3095084A1 (en) | 2018-04-05 | 2019-10-10 | Juno Therapeutics, Inc. | T cells expressing a recombinant receptor, related polynucleotides and methods |
| KR20210029707A (ko) | 2018-04-05 | 2021-03-16 | 주노 쎄러퓨티크스 인코퍼레이티드 | 재조합 수용체를 발현하는 세포의 생산 방법 및 관련 조성물 |
| CN112262212B (zh) | 2018-04-24 | 2024-07-12 | 美国卫生和人力服务部 | 使用羟基柠檬酸和/或其盐产生t细胞群体的方法 |
| US20210155941A1 (en) * | 2018-06-22 | 2021-05-27 | Kite Pharma Eu B.V. | Compositions and methods for making engineered t cells |
| CN112955465A (zh) | 2018-07-03 | 2021-06-11 | 马伦戈治疗公司 | 抗tcr抗体分子及其用途 |
| CN113474450A (zh) | 2018-08-09 | 2021-10-01 | 朱诺治疗学股份有限公司 | 产生工程化细胞的方法以及所述工程化细胞的组合物 |
| US12366580B2 (en) | 2018-09-11 | 2025-07-22 | Juno Therapeutics, Inc. | Methods for mass spectrometry analysis of engineered cell compositions |
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| CN110357952B (zh) * | 2019-07-17 | 2022-03-22 | 深圳市因诺转化医学研究院 | 识别人乳头瘤病毒hpv16-e7抗原的tcr |
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