CY1122790T1 - Αντι-ανθρωπινου ιου των θηλωματων 16 ε7 τ κυτταρου υποδοχεις - Google Patents

Αντι-ανθρωπινου ιου των θηλωματων 16 ε7 τ κυτταρου υποδοχεις

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CY1122790T1
CY1122790T1 CY20201100238T CY201100238T CY1122790T1 CY 1122790 T1 CY1122790 T1 CY 1122790T1 CY 20201100238 T CY20201100238 T CY 20201100238T CY 201100238 T CY201100238 T CY 201100238T CY 1122790 T1 CY1122790 T1 CY 1122790T1
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hpv
condition
cell receptor
human mammal
mammal
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CY20201100238T
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Christian S. HINRICHS
Steven A. Rosenberg
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The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
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    • G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus

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Abstract

Αποκαλυπτόμενος είναι ένας συνθετικός υποδοχέας Τ κυττάρου (ΤCR) που έχει αντιγονική ειδικότητα για ΗLΑ-Α2 περιορισμένο επίτοπο του ανθρώπινου ιού των θηλωμάτων (ΗΡV) 16 Ε7, Ε711-19. Σχετικά πολυπεπτίδια και πρωτεΐνες, καθώς επίσης σχετικά νουκλεϊνικά οξέα, ανασυνδυαστικοί φορείς έκφρασης, κύτταρα ξενιστές και πληθυσμοί κυττάρων επίσης παρέχονται. Αντισώματα ή τμήμα σύνδεσης αντιγόνου αυτών και φαρμακευτικές συνθέσεις που αφορούν τους ΤCRs της εφεύρεσης επίσης παρέχονται. Επίσης αποκαλυπτόμενες είναι μέθοδοι ανίχνευσης της παρουσίας μιας κατάστασης σε ένα θηλαστικό και μέθοδοι θεραπείας ή πρόληψης μιας κατάστασης σε ένα θηλαστικό, όπου η κατάσταση είναι καρκίνος, ΗΡV 16 μόλυνση ή ΗΡV-θετική προκακοήθεια.
CY20201100238T 2014-05-29 2020-03-16 Αντι-ανθρωπινου ιου των θηλωματων 16 ε7 τ κυτταρου υποδοχεις CY1122790T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462004335P 2014-05-29 2014-05-29
PCT/US2015/033129 WO2015184228A1 (en) 2014-05-29 2015-05-29 Anti-human papillomavirus 16 e7 t cell receptors

Publications (1)

Publication Number Publication Date
CY1122790T1 true CY1122790T1 (el) 2021-05-05

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US (4) US10174098B2 (el)
EP (2) EP3149031B1 (el)
JP (4) JP6742991B2 (el)
KR (2) KR102618267B1 (el)
CN (2) CN113150112B (el)
AU (4) AU2015266818B2 (el)
BR (1) BR112016027805A2 (el)
CA (1) CA2950192A1 (el)
CY (1) CY1122790T1 (el)
DK (1) DK3149031T3 (el)
ES (1) ES2784237T3 (el)
HR (1) HRP20200376T1 (el)
IL (3) IL290655B2 (el)
LT (1) LT3149031T (el)
MX (2) MX2016015383A (el)
PL (1) PL3149031T3 (el)
PT (1) PT3149031T (el)
SA (1) SA516380394B1 (el)
SI (1) SI3149031T1 (el)
WO (1) WO2015184228A1 (el)

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