CN1121379C - 具负性激素和/或拮抗剂活性视黄醛衍生物的合成和用途 - Google Patents

具负性激素和/或拮抗剂活性视黄醛衍生物的合成和用途 Download PDF

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CN1121379C
CN1121379C CN96197896A CN96197896A CN1121379C CN 1121379 C CN1121379 C CN 1121379C CN 96197896 A CN96197896 A CN 96197896A CN 96197896 A CN96197896 A CN 96197896A CN 1121379 C CN1121379 C CN 1121379C
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compound
carbon atom
phenyl
formula
solution
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CN1209802A (zh
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E·S·克莱恩
A·T·约翰森
A·M·斯坦德文
R·L·贝尔德
S·T·吉勒特
杨翠仙
S·纳帕尔
V·维利贡达
滕敏
R·A·钱德拉拉纳
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Allergan Inc
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    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
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    • C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • C07C245/10—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems
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    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/90—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl and carboxyl groups
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    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
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  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN96197896A 1995-09-01 1996-08-23 具负性激素和/或拮抗剂活性视黄醛衍生物的合成和用途 Expired - Fee Related CN1121379C (zh)

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Application Number Priority Date Filing Date Title
US52277895A 1995-09-01 1995-09-01
US52277995A 1995-09-01 1995-09-01
US54264895A 1995-10-13 1995-10-13
US08/522,778 1996-03-11
US08/613,863 1996-03-11
US08/522,779 1996-03-11
US08/613,863 US5776699A (en) 1995-09-01 1996-03-11 Method of identifying negative hormone and/or antagonist activities
US08/542,648 1996-03-11

Related Child Applications (1)

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CN01143840A Division CN1360890A (zh) 1995-09-01 2001-12-10 具负性激素和/或拮抗剂活性视黄醛衍生物的用途

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CN1209802A CN1209802A (zh) 1999-03-03
CN1121379C true CN1121379C (zh) 2003-09-17

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CN96197896A Expired - Fee Related CN1121379C (zh) 1995-09-01 1996-08-23 具负性激素和/或拮抗剂活性视黄醛衍生物的合成和用途
CN01143840A Pending CN1360890A (zh) 1995-09-01 2001-12-10 具负性激素和/或拮抗剂活性视黄醛衍生物的用途

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US (1) US5776699A (https=)
EP (2) EP0931786B1 (https=)
JP (1) JP4295357B2 (https=)
KR (3) KR100447047B1 (https=)
CN (2) CN1121379C (https=)
AT (2) ATE233726T1 (https=)
AU (1) AU713586B2 (https=)
BR (1) BR9610412A (https=)
CA (1) CA2230672C (https=)
CZ (1) CZ62198A3 (https=)
DE (2) DE69629399T2 (https=)
ES (2) ES2205380T3 (https=)
HU (2) HU0202511D0 (https=)
IL (5) IL153296A0 (https=)
NO (1) NO317562B1 (https=)
NZ (2) NZ500397A (https=)
PL (1) PL188705B1 (https=)
RU (1) RU2203884C2 (https=)
WO (1) WO1997009297A2 (https=)

Cited By (1)

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CN107176945A (zh) * 2016-03-11 2017-09-19 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用

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GB9222253D0 (en) * 1992-10-23 1992-12-09 Celltech Ltd Chemical compounds
GB9304919D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
GB9304920D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
EP0738268B1 (en) * 1993-12-22 2004-03-03 Celltech R&D Limited Trisubstituted phenyl derivatives, processes for their preparation and their use as phosphodiesterase (type iv) inhibitors
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
US6942980B1 (en) * 1995-09-01 2005-09-13 Allergan, Inc. Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
US5958954A (en) * 1995-09-01 1999-09-28 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
GB9523675D0 (en) * 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
GB9526245D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9526243D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
US5877207A (en) * 1996-03-11 1999-03-02 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
CN1255396C (zh) * 1996-03-18 2006-05-10 卫材株式会社 含有稠环的羧酸衍生物
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