CN111655252A - 含有亚铁氨基酸粒子的组合物及其用于制造治疗或改善胰脏相关疾病的医药品的用途 - Google Patents
含有亚铁氨基酸粒子的组合物及其用于制造治疗或改善胰脏相关疾病的医药品的用途 Download PDFInfo
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- CN111655252A CN111655252A CN201880086420.2A CN201880086420A CN111655252A CN 111655252 A CN111655252 A CN 111655252A CN 201880086420 A CN201880086420 A CN 201880086420A CN 111655252 A CN111655252 A CN 111655252A
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Abstract
本发明提供一种组合物，其中该组合物中含有由亚铁氨基酸螯合物烧结而成的亚铁氨基酸螯合物粒子，且所述亚铁氨基酸螯合物粒子的平均粒径为500纳米至2600纳米、平均分子量为1,500道尔顿(Dalton)至600,000道尔顿。且本发明的组合物可用于制备治疗或改善胰脏相关疾病的医药品的用途，其中所述医药品含有有效剂量的所述组合物以及药学上可接受的载剂。
Description
PCT国内申请，说明书已公开。
Claims (12)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2018/122406 WO2020124495A1 (zh) | 2018-12-20 | 2018-12-20 | 含有亚铁氨基酸粒子的组合物及其用于制造治疗或改善胰脏相关疾病的医药品的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111655252A true CN111655252A (zh) | 2020-09-11 |
| CN111655252B CN111655252B (zh) | 2021-08-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880086420.2A Expired - Fee Related CN111655252B (zh) | 2018-12-20 | 2018-12-20 | 含有亚铁氨基酸粒子的组合物用于制备减缓胰脏癌产生的腹水及治疗胰脏炎的医药品的用途 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220031651A1 (zh) |
| EP (1) | EP3900719A4 (zh) |
| JP (1) | JP6998087B2 (zh) |
| CN (1) | CN111655252B (zh) |
| AU (1) | AU2018454589A1 (zh) |
| CA (1) | CA3087911A1 (zh) |
| WO (1) | WO2020124495A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114767710B (zh) * | 2022-04-12 | 2023-07-07 | 中山大学 | 甘氨酸亚铁在治疗类风湿关节炎中的应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104955452B (zh) * | 2013-09-05 | 2017-06-09 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物在制备抗癌症的药物中的用途 |
| WO2017201701A1 (zh) * | 2016-05-26 | 2017-11-30 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物用于制造降低乳酸的药物的用途 |
| WO2018098804A1 (zh) * | 2016-12-02 | 2018-06-07 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物用于制造防止癌症转移的医药品的用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002030947A2 (en) | 2000-10-11 | 2002-04-18 | Albion International, Inc. | Compositions and methods of preparing amino acid chelates and complexes |
| US20060134227A1 (en) | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Compositions including iron |
| US8007846B2 (en) | 2006-01-18 | 2011-08-30 | Albion International, Inc. | Mixed amino acid/mineral compounds having improved solubility |
| TWI483721B (zh) | 2013-09-05 | 2015-05-11 | Profeat Biotechnology Co Ltd | The use of a composition containing a ferrous amino acid chelate for the manufacture of anti-cancer medicaments |
| CN108371668B (zh) * | 2018-02-25 | 2020-11-24 | 四川大学 | 具有抗肿瘤作用的纳米羟基磷灰石粒子及制备方法和用途 |
| US11141382B2 (en) | 2018-03-06 | 2021-10-12 | Profeat Biotechnology Co., Ltd. | Sintered nanoparticles and use of the same against a virus |
| US11110065B2 (en) | 2018-03-06 | 2021-09-07 | Profeat Biotechnology Co., Ltd. | Sintered ferrous amino acid particles and use of the same against a virus |
| US10813906B2 (en) | 2018-04-13 | 2020-10-27 | Profeat Biotechnology Co., Ltd. | Use of ferrous amino acid chelate to treat infection by enteropathogen and to enhance growth performance |
-
2018
- 2018-12-20 CN CN201880086420.2A patent/CN111655252B/zh not_active Expired - Fee Related
- 2018-12-20 JP JP2020540748A patent/JP6998087B2/ja active Active
- 2018-12-20 US US16/965,181 patent/US20220031651A1/en active Pending
- 2018-12-20 AU AU2018454589A patent/AU2018454589A1/en not_active Abandoned
- 2018-12-20 WO PCT/CN2018/122406 patent/WO2020124495A1/zh unknown
- 2018-12-20 CA CA3087911A patent/CA3087911A1/en not_active Abandoned
- 2018-12-20 EP EP18943815.3A patent/EP3900719A4/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104955452B (zh) * | 2013-09-05 | 2017-06-09 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物在制备抗癌症的药物中的用途 |
| WO2017201701A1 (zh) * | 2016-05-26 | 2017-11-30 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物用于制造降低乳酸的药物的用途 |
| WO2018098804A1 (zh) * | 2016-12-02 | 2018-06-07 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物用于制造防止癌症转移的医药品的用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3900719A4 (en) | 2022-08-03 |
| WO2020124495A1 (zh) | 2020-06-25 |
| JP6998087B2 (ja) | 2022-02-04 |
| CA3087911A1 (en) | 2020-06-25 |
| JP2021511358A (ja) | 2021-05-06 |
| CN111655252B (zh) | 2021-08-06 |
| US20220031651A1 (en) | 2022-02-03 |
| EP3900719A1 (en) | 2021-10-27 |
| AU2018454589A1 (en) | 2020-08-06 |
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