CN110461315B - 使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征 - Google Patents

使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征 Download PDF

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CN110461315B
CN110461315B CN201780054186.0A CN201780054186A CN110461315B CN 110461315 B CN110461315 B CN 110461315B CN 201780054186 A CN201780054186 A CN 201780054186A CN 110461315 B CN110461315 B CN 110461315B
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CN110461315A (zh
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S·吉尔
S·肯德利安
M·鲁艾拉
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Novartis AG
University of Pennsylvania
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma

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CN201780054186.0A 2016-07-15 2017-07-14 使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征 Active CN110461315B (zh)

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US201662362659P 2016-07-15 2016-07-15
US62/362,659 2016-07-15
US201662366997P 2016-07-26 2016-07-26
US62/366,997 2016-07-26
US201662381230P 2016-08-30 2016-08-30
US62/381,230 2016-08-30
PCT/US2017/042129 WO2018013918A2 (en) 2016-07-15 2017-07-14 Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor

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CN202510483434.XA Pending CN120285179A (zh) 2016-07-15 2017-07-14 使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征

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US (1) US20190336504A1 (enExample)
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JP (3) JP7219376B2 (enExample)
CN (2) CN110461315B (enExample)
AU (2) AU2017295886C1 (enExample)
CA (1) CA3030837A1 (enExample)
SG (1) SG11201900344YA (enExample)
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