CN110279684B - 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 - Google Patents
用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 Download PDFInfo
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- CN110279684B CN110279684B CN201910497947.0A CN201910497947A CN110279684B CN 110279684 B CN110279684 B CN 110279684B CN 201910497947 A CN201910497947 A CN 201910497947A CN 110279684 B CN110279684 B CN 110279684B
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361773773P | 2013-03-06 | 2013-03-06 | |
| US61/773,773 | 2013-03-06 | ||
| PCT/US2014/020245 WO2014138037A1 (en) | 2013-03-06 | 2014-03-04 | Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases |
| CN201480012204.5A CN105007909B (zh) | 2013-03-06 | 2014-03-04 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480012204.5A Division CN105007909B (zh) | 2013-03-06 | 2014-03-04 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110279684A CN110279684A (zh) | 2019-09-27 |
| CN110279684B true CN110279684B (zh) | 2023-02-28 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910497947.0A Active CN110279684B (zh) | 2013-03-06 | 2014-03-04 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
| CN201480012204.5A Active CN105007909B (zh) | 2013-03-06 | 2014-03-04 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480012204.5A Active CN105007909B (zh) | 2013-03-06 | 2014-03-04 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
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| EP (2) | EP2964213B1 (enExample) |
| JP (4) | JP6196327B2 (enExample) |
| KR (2) | KR102227201B1 (enExample) |
| CN (2) | CN110279684B (enExample) |
| AR (1) | AR095034A1 (enExample) |
| AU (3) | AU2014225992B2 (enExample) |
| BR (2) | BR112015021371B1 (enExample) |
| CA (2) | CA3133264A1 (enExample) |
| CL (3) | CL2015002485A1 (enExample) |
| ES (2) | ES2835825T3 (enExample) |
| IL (3) | IL241012B (enExample) |
| MX (2) | MX364916B (enExample) |
| MY (1) | MY207109A (enExample) |
| PH (3) | PH12020500285B1 (enExample) |
| RU (2) | RU2768730C2 (enExample) |
| SG (2) | SG11201507113RA (enExample) |
| TW (1) | TWI616200B (enExample) |
| WO (1) | WO2014138037A1 (enExample) |
| ZA (1) | ZA201505134B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012329098B2 (en) * | 2011-10-26 | 2017-08-03 | Allergan, Inc. | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
| SG11201406629VA (en) * | 2012-04-16 | 2014-11-27 | Allergan Inc | (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators |
| TW201348219A (zh) | 2012-05-16 | 2013-12-01 | Actelion Pharmaceuticals Ltd | 作爲alx受體激動劑之經1-(對-甲苯基)環丙基取代橋聯螺[2.4]庚烷衍生物 |
| MA37618B1 (fr) | 2012-05-16 | 2017-08-31 | Actelion Pharmaceuticals Ltd | Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx |
| CN107312039B (zh) | 2012-08-30 | 2019-06-25 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药的制备方法 |
| CN110279684B (zh) * | 2013-03-06 | 2023-02-28 | 阿勒根公司 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
| JP6196328B2 (ja) | 2013-03-06 | 2017-09-13 | アラーガン、インコーポレイテッドAllergan,Incorporated | 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用 |
| AR096686A1 (es) | 2013-06-25 | 2016-01-27 | Actelion Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx |
| US9428549B2 (en) * | 2013-07-16 | 2016-08-30 | Allegran, Inc. | Derivatives of N-urea substituted amino acids as formyl peptide receptor modulators |
| ES2639798T3 (es) | 2013-07-18 | 2017-10-30 | Idorsia Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano con puente sustituidos con piperazina como agonistas del receptor ALX |
| AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
| US9663457B2 (en) | 2014-04-09 | 2017-05-30 | Allergan, Inc. | Carbamoyl hydrazine derivatives as formyl peptide modulators |
| ES2788700T3 (es) | 2014-05-21 | 2020-10-22 | Allergan Inc | Derivados de imidazol como moduladores del receptor de péptido formilado |
| WO2016149667A1 (en) | 2015-03-19 | 2016-09-22 | University Of Maryland , Baltimore | Runx2 transcription factor inhibitors and uses thereof |
| EP3303284B1 (en) | 2015-05-27 | 2020-04-08 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
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