MX364916B - Uso de agonistas de receptor de péptido formilo 2 para tratar enfermadades inflamatorias oculares. - Google Patents

Uso de agonistas de receptor de péptido formilo 2 para tratar enfermadades inflamatorias oculares.

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Publication number
MX364916B
MX364916B MX2015011593A MX2015011593A MX364916B MX 364916 B MX364916 B MX 364916B MX 2015011593 A MX2015011593 A MX 2015011593A MX 2015011593 A MX2015011593 A MX 2015011593A MX 364916 B MX364916 B MX 364916B
Authority
MX
Mexico
Prior art keywords
inflammatory diseases
agonists
peptide receptor
treating ocular
ocular inflammatory
Prior art date
Application number
MX2015011593A
Other languages
English (en)
Other versions
MX2015011593A (es
Inventor
E Donello John
L Beard Richard
Viswanath Veena
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of MX2015011593A publication Critical patent/MX2015011593A/es
Publication of MX364916B publication Critical patent/MX364916B/es

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract

La presente invención se refiere a un método para tratar enfermedades inflamatorias oculares en un sujeto que necesita dicho tratamiento, que comprende administrar un composición farmacéutica que comprende una cantidad terapéuticamente eficaz de al menos un agonista del receptor de péptido formilo 2.
MX2015011593A 2013-03-06 2014-03-04 Uso de agonistas de receptor de péptido formilo 2 para tratar enfermadades inflamatorias oculares. MX364916B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361773773P 2013-03-06 2013-03-06
PCT/US2014/020245 WO2014138037A1 (en) 2013-03-06 2014-03-04 Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases

Publications (2)

Publication Number Publication Date
MX2015011593A MX2015011593A (es) 2015-12-09
MX364916B true MX364916B (es) 2019-05-13

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MX2015011593A MX364916B (es) 2013-03-06 2014-03-04 Uso de agonistas de receptor de péptido formilo 2 para tratar enfermadades inflamatorias oculares.

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US (3) US9850264B2 (es)
EP (2) EP3795148A1 (es)
JP (4) JP6196327B2 (es)
KR (2) KR102227201B1 (es)
CN (2) CN105007909B (es)
AR (1) AR095034A1 (es)
AU (3) AU2014225992B2 (es)
BR (2) BR122017004254B1 (es)
CA (2) CA3133264A1 (es)
CL (3) CL2015002485A1 (es)
ES (1) ES2835825T3 (es)
HK (1) HK1219657A1 (es)
IL (3) IL241012B (es)
MX (1) MX364916B (es)
PH (3) PH12015501858B1 (es)
RU (2) RU2768730C2 (es)
SG (2) SG10201801471RA (es)
TW (1) TWI616200B (es)
WO (1) WO2014138037A1 (es)

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WO2013158597A1 (en) * 2012-04-16 2013-10-24 Allergan, Inc. (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
EP2850058B1 (en) 2012-05-16 2016-07-13 Actelion Pharmaceuticals Ltd. 1-(p-tolyl)cyclopropyl substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists
MA37618B1 (fr) 2012-05-16 2017-08-31 Actelion Pharmaceuticals Ltd Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
JP6196327B2 (ja) 2013-03-06 2017-09-13 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 眼炎症性疾患の治療のためのホルミルペプチド受容体２のアゴニストの使用
KR20210024691A (ko) 2013-03-06 2021-03-05 알러간, 인코포레이티드 피부 질환 치료용 포르밀 펩티드 수용체 2의 항진제의 용도
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AU2014292064B2 (en) 2013-07-18 2018-07-05 Idorsia Pharmaceuticals Ltd Piperazine substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists
AR097279A1 (es) 2013-08-09 2016-03-02 Actelion Pharmaceuticals Ltd Derivados de benzimidazolil-metil urea como agonistas del receptor de alx
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EP3303284B1 (en) 2015-05-27 2020-04-08 Kyorin Pharmaceutical Co., Ltd. Urea derivative or pharmacologically acceptable salt thereof
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