CN109952112B - Cd123结合蛋白和相关的组合物和方法 - Google Patents

Cd123结合蛋白和相关的组合物和方法 Download PDF

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CN109952112B
CN109952112B CN201780069428.3A CN201780069428A CN109952112B CN 109952112 B CN109952112 B CN 109952112B CN 201780069428 A CN201780069428 A CN 201780069428A CN 109952112 B CN109952112 B CN 109952112B
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amino acid
polypeptide
acid sequence
binding domain
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CN109952112A (zh
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G·贺尔南德兹-霍约斯
E·T·塞韦尔
C·J·麦克马汉
D·比恩维依
J·W·布兰肯什普
D·米切尔
P·帕夫利克
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Aptevo Research and Development LLC
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    • C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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CN201780069428.3A 2016-09-21 2017-09-21 Cd123结合蛋白和相关的组合物和方法 Active CN109952112B (zh)

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US201662397736P 2016-09-21 2016-09-21
US62/397,736 2016-09-21
US201762466192P 2017-03-02 2017-03-02
US62/466,192 2017-03-02
PCT/US2017/052808 WO2018057802A1 (en) 2016-09-21 2017-09-21 Cd123 binding proteins and related compositions and methods

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CN109952112B true CN109952112B (zh) 2024-09-06

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