CN109562057A - 聚乙二醇化脂质体和使用方法 - Google Patents

聚乙二醇化脂质体和使用方法 Download PDF

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Publication number
CN109562057A
CN109562057A CN201780030294.4A CN201780030294A CN109562057A CN 109562057 A CN109562057 A CN 109562057A CN 201780030294 A CN201780030294 A CN 201780030294A CN 109562057 A CN109562057 A CN 109562057A
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China
Prior art keywords
liposome
antigen
lipid
composition
pegylated
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Pending
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CN201780030294.4A
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English (en)
Chinese (zh)
Inventor
C·B·福克斯
S·S·林
D·卡特
N·范霍温
M·M·阿布海恩卡
W·A·小彼得里
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Institute Of Infectious Diseases
UVA Licensing and Ventures Group
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Institute Of Infectious Diseases
University of Virginia Patent Foundation
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Publication of CN109562057A publication Critical patent/CN109562057A/zh
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
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    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201780030294.4A 2016-05-16 2017-05-15 聚乙二醇化脂质体和使用方法 Pending CN109562057A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662337328P 2016-05-16 2016-05-16
US62/337,328 2016-05-16
PCT/US2017/032756 WO2017200957A1 (en) 2016-05-16 2017-05-15 Pegylated liposomes and methods of use

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CN109562057A true CN109562057A (zh) 2019-04-02

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US (3) US11266602B2 (enExample)
EP (1) EP3458028A1 (enExample)
JP (2) JP7195147B2 (enExample)
KR (1) KR102483033B1 (enExample)
CN (1) CN109562057A (enExample)
AU (2) AU2017268175B2 (enExample)
BR (1) BR112018073676B1 (enExample)
CA (1) CA3023672A1 (enExample)
IL (3) IL263030B2 (enExample)
MX (1) MX2018013640A (enExample)
WO (1) WO2017200957A1 (enExample)
ZA (1) ZA201807128B (enExample)

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CN110151702A (zh) * 2019-06-24 2019-08-23 昆明医科大学 聚乙二醇修饰流感疫苗脂质体及其制备方法
CN115737800A (zh) * 2023-01-09 2023-03-07 江苏瑞科生物技术股份有限公司 一种复合脂质体佐剂及其制备方法

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JP7195147B2 (ja) 2016-05-16 2022-12-23 アクセス ツー アドバンスト ヘルス インスティチュート Ｐｅｇ化リポソームおよび使用方法
CN107998070A (zh) * 2017-12-12 2018-05-08 南京中医药大学 一种复合磷脂传递体及其在制备经皮给药制剂中的应用
WO2020109365A1 (en) * 2018-11-29 2020-06-04 Glaxosmithkline Biologicals Sa Methods for manufacturing an adjuvant
WO2020129826A1 (en) * 2018-12-17 2020-06-25 Eisai R&D Management Co., Ltd. Formulation comprising liposomes
US11679163B2 (en) 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
KR102328531B1 (ko) * 2020-01-23 2021-11-17 서울대학교산학협력단 체내 면역 세포 표적 황화수소 공여체 담지 리포좀을 포함하는 면역질환 치료 또는 예방용 약학 조성물
CA3172489A1 (en) 2020-03-23 2021-09-30 Amit KHANDHAR Nanoemulsion compositions and methods for delivery of nra
WO2022020542A1 (en) * 2020-07-22 2022-01-27 University Of Houston System Treatment and prevention of conditions associated with respiratory diseases
JP2024501949A (ja) 2020-12-23 2024-01-17 アクセス ツー アドバンスト ヘルス インスティチュート ソラネソールワクチンアジュバント及びその調製方法
US20240180834A1 (en) * 2021-02-26 2024-06-06 Univesity Of Virginia Patent Foundation Development of covid-19 vaccine using a dual tlr ligand liposome adjuvant
WO2022192674A1 (en) * 2021-03-11 2022-09-15 The Trustees Of The University Of Pennsylvania Targeted therapeutic lipid nanoparticles and methods of use
KR102682082B1 (ko) * 2021-06-01 2024-07-05 서울대학교산학협력단 리포좀 및 이를 포함하는 암 방사선 치료용 약학 조성물
EP4404957A4 (en) 2021-09-22 2025-08-06 Hdt Bio Corp CANCER THERAPY COMPOSITIONS AND THEIR USES
CA3232719A1 (en) 2021-09-22 2023-03-30 Steven Gregory REED Sars-cov-2 rna vaccine compositions and methods of use
AU2022351009A1 (en) 2021-09-22 2024-04-11 Hdt Bio Corp. Rna vaccines against infectious diseases
AU2022352486A1 (en) 2021-09-22 2024-04-11 Hdt Bio Corp. Dried nanoparticle compositions
WO2024137455A1 (en) * 2022-12-19 2024-06-27 Newimmune Ii, Llc Nanoparticulate formulation
WO2025245466A1 (en) * 2024-05-24 2025-11-27 Curevo, Inc. Immunogenic compositions for the prevention of herpes zoster

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