DE122007000014I1 - Herstellung von menschlichem Papillomavirus Hüllprotein und virus-ähnlichen Teilchen - Google Patents
Herstellung von menschlichem Papillomavirus Hüllprotein und virus-ähnlichen TeilchenInfo
- Publication number
- DE122007000014I1 DE122007000014I1 DE1994634383 DE69434383C DE122007000014I1 DE 122007000014 I1 DE122007000014 I1 DE 122007000014I1 DE 1994634383 DE1994634383 DE 1994634383 DE 69434383 C DE69434383 C DE 69434383C DE 122007000014 I1 DE122007000014 I1 DE 122007000014I1
- Authority
- DE
- Germany
- Prior art keywords
- virus
- particles
- production
- envelope protein
- human papillomavirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 title abstract 2
- 101710091045 Envelope protein Proteins 0.000 title 1
- 241000701806 Human papillomavirus Species 0.000 title 1
- 101710188315 Protein X Proteins 0.000 title 1
- 102100021696 Syncytin-1 Human genes 0.000 title 1
- 241001631646 Papillomaviridae Species 0.000 abstract 2
- 108090000565 Capsid Proteins Proteins 0.000 abstract 1
- 102100023321 Ceruloplasmin Human genes 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 210000000234 capsid Anatomy 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/028,517 US8062642B1 (en) | 1993-03-09 | 1993-03-09 | Production of papillomavirus capsid protein and virus-like particles |
US20730994A | 1994-03-07 | 1994-03-07 | |
PCT/US1994/002443 WO1994020137A1 (en) | 1993-03-09 | 1994-03-08 | Production of human papillomavirus capsid protein and virus-like particles |
Publications (1)
Publication Number | Publication Date |
---|---|
DE122007000014I1 true DE122007000014I1 (de) | 2007-05-24 |
Family
ID=26703787
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69435332T Expired - Lifetime DE69435332D1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papillomaviren Hüllprotein und Virus-ähnlichen Teilchen |
DE69434383T Expired - Lifetime DE69434383T2 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen |
DE201112100018 Pending DE122011100018I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusahnlichen Teilchen. |
DE69435331T Expired - Lifetime DE69435331D1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichen papillomavirus HBV-11 Kapsidprotein L1 und Virus-ähnliche Partikeln |
DE1994634383 Pending DE122007000014I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papillomavirus Hüllprotein und virus-ähnlichen Teilchen |
DE122007000090C Pending DE122007000090I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen |
DE05075369T Pending DE05075369T1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusähnlichen Teilchen |
DE122007000089C Pending DE122007000089I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen |
DE05075889T Pending DE05075889T1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papilloma-Virus HBV-11-Capsid-Protein L1 und virusähnlichen Teilchen |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69435332T Expired - Lifetime DE69435332D1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papillomaviren Hüllprotein und Virus-ähnlichen Teilchen |
DE69434383T Expired - Lifetime DE69434383T2 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen |
DE201112100018 Pending DE122011100018I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusahnlichen Teilchen. |
DE69435331T Expired - Lifetime DE69435331D1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichen papillomavirus HBV-11 Kapsidprotein L1 und Virus-ähnliche Partikeln |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE122007000090C Pending DE122007000090I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen |
DE05075369T Pending DE05075369T1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusähnlichen Teilchen |
DE122007000089C Pending DE122007000089I1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen |
DE05075889T Pending DE05075889T1 (de) | 1993-03-09 | 1994-03-08 | Herstellung von menschlichem Papilloma-Virus HBV-11-Capsid-Protein L1 und virusähnlichen Teilchen |
Country Status (14)
Country | Link |
---|---|
EP (3) | EP1618888B1 (de) |
JP (4) | JPH08507685A (de) |
AT (3) | ATE296111T1 (de) |
AU (3) | AU688759C (de) |
CA (1) | CA2157932C (de) |
DE (9) | DE69435332D1 (de) |
DK (2) | DK1618888T3 (de) |
ES (3) | ES2263405T3 (de) |
FR (1) | FR11C0022I2 (de) |
HK (2) | HK1082196A1 (de) |
LU (3) | LU91313I2 (de) |
NL (3) | NL300265I2 (de) |
PT (2) | PT1618888E (de) |
WO (1) | WO1994020137A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE122007000018I1 (de) | 1991-07-19 | 2007-05-24 | Univ Queensland | Polynukleotidabschnitt des HPV16-Genoms |
US5437951A (en) * | 1992-09-03 | 1995-08-01 | The United States Of America As Represented By The Department Of Health And Human Services | Self-assembling recombinant papillomavirus capsid proteins |
US6153201A (en) * | 1993-03-09 | 2000-11-28 | University Of Rochester | Oral immunization with papillomavirus virus-like particles |
AUPM358894A0 (en) * | 1994-01-31 | 1994-02-24 | Csl Limited | Modified papilloma virus l2 protein and vlps formed therefrom |
DE4415743C2 (de) * | 1994-05-04 | 1996-10-10 | Deutsches Krebsforsch | Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen |
US5888516A (en) * | 1994-05-16 | 1999-03-30 | Merck & Co. Inc. | Recombinant papillomavirus vaccines |
AUPM566794A0 (en) * | 1994-05-17 | 1994-06-09 | University Of Queensland, The | Process and product |
AU2003235191B2 (en) * | 1994-10-07 | 2006-09-21 | Loyola University Of Chicago | Papilloma virus-like particles, fusion proteins as well as processes for their production |
AU4270196A (en) | 1994-10-07 | 1996-05-02 | Lutz Gissmann | Papilloma virus-like particles, fusion proteins and process for producing the same |
AR004464A1 (es) * | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
EP0812358A1 (de) * | 1995-02-24 | 1997-12-17 | Cantab Pharmaceuticals Research Limited | Polypeptide verwendbar als immunotherapeutischen mitteln und verfahren zur bereitung von polypeptiden |
US5820870A (en) * | 1995-03-22 | 1998-10-13 | Merck & Co., Inc. | Recombinant human papillomavirus type 18 vaccine |
IL117459A (en) * | 1995-03-22 | 2005-11-20 | Merck & Co Inc | Dna encoding human papillomavirus type 18 |
US5840306A (en) * | 1995-03-22 | 1998-11-24 | Merck & Co., Inc. | DNA encoding human papillomavirus type 18 |
US5821087A (en) * | 1995-03-30 | 1998-10-13 | Merck & Co., Inc. | Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA |
IL117591A0 (en) * | 1995-03-30 | 1996-07-23 | Merck & Co Inc | Synthetic DNA encoding human papillomavirus type 11 L1 protein |
EP0863982B1 (de) * | 1995-11-15 | 2004-01-21 | Merck & Co., Inc. | Synthetische hpv11 virusartige partikel |
DE19543553B4 (de) * | 1995-11-22 | 2009-04-09 | Deutsches Primatenzentrum Gmbh | VP-Antigene des JC-Virus |
US6908615B1 (en) | 1996-03-18 | 2005-06-21 | Merck & Co., Inc. | DNA encoding human papilloma virus type 18 |
FR2749323B1 (fr) * | 1996-06-04 | 1998-07-10 | Pasteur Merieux Serums Vacc | Pseudo-particules virales utiles en tant que vecteur de delivrance d'acide nucleique |
EP0956349B1 (de) * | 1996-10-04 | 2003-12-17 | Merck & Co., Inc. (a New Jersey corp.) | Synthetische hpv16 virus-ähnliche partikel |
EP0948351B1 (de) * | 1996-12-09 | 2004-02-25 | Merck & Co., Inc. | Synthetische hpv-16 virusähnliche partikel |
US6228368B1 (en) * | 1997-10-06 | 2001-05-08 | Loyola University Of Chicago | Papilloma virus capsomere formulations and method of use |
CA2229955C (en) | 1998-02-20 | 2003-12-09 | Medigene Gmbh | Papilloma virus capsomere vaccine formulations and methods of use |
US7494658B2 (en) | 1998-02-20 | 2009-02-24 | Medigene Ag | Papilloma virus truncated L1 protein and fusion protein constructs |
US7182947B2 (en) | 1998-02-20 | 2007-02-27 | Medigene Ag | Papillomavirus truncated L1 protein and fusion protein constructs |
US20020039584A1 (en) | 1998-02-20 | 2002-04-04 | Medigene Ag | Papilloma virus capsomere vaccine formulations and methods of use |
US6926897B1 (en) | 1998-03-24 | 2005-08-09 | Medigene Aktiengesellschaft | Medicament for the avoidance or treatment of papillomavirus-specific tumour |
US6692752B1 (en) | 1999-09-08 | 2004-02-17 | Smithkline Beecham Biologicals S.A. | Methods of treating human females susceptible to HSV infection |
DE19925235A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
DE19925199A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
AU2001294565A1 (en) * | 2000-09-18 | 2002-04-02 | Med Immune, Inc. | In vitro assay for measuring the immunogenicity of a vaccine |
GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
EP1425423B1 (de) | 2001-08-13 | 2010-06-23 | University of Rochester | Transkutane immunisierung gegen papillomavirus mit virusähnlichen papillomaviruspartikeln |
GB0206360D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
CA2531773A1 (en) | 2003-07-21 | 2005-02-17 | Transgene S.A. | Novel multifunctional cytokines |
EP1877087B1 (de) | 2005-04-15 | 2013-02-20 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Verfahren und zusammensetzungen zur erzeugung einer verbesserten immunantwort auf ein menschliches papillomavirus-immunogen |
WO2006065166A1 (fr) * | 2005-07-26 | 2006-06-22 | Obschestvo S Ogranichennoi Otvetstvennostyu 'rusgen' | Composition de traitement et de prevention de l'infection de l'humain par le papillomavirus sur la base de la proteine l1 et des peptides de la proteine e7 |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
WO2008082719A2 (en) | 2006-08-30 | 2008-07-10 | University Of Rochester | Combined human papillomavirus vlp/gene delivery system and use thereof as a vaccine for prophylaxis and immunotherapy of infectious diseases and tumors |
EP2068918B1 (de) | 2006-09-26 | 2012-05-02 | Infectious Disease Research Institute | Impfstoffzusammensetzung mit einem synthetischen adjuvans |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
EA021391B1 (ru) | 2007-03-02 | 2015-06-30 | Глаксосмитклайн Байолоджикалс С.А. | Способ индукции иммунного ответа, вакцинная композиция, ее применение и набор |
US9428555B2 (en) | 2007-04-29 | 2016-08-30 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | Truncated L1 protein of Human Papillomavirus type 16 |
US9364529B2 (en) | 2007-04-29 | 2016-06-14 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | Truncated L1 protein of human papillomavirus type 18 |
EP2910566B1 (de) | 2007-05-29 | 2016-07-13 | Xiamen University | Verkürztes L1-Protein des humanen Papillomavirus 11 |
DK2154149T3 (da) * | 2007-05-29 | 2019-10-14 | Univ Xiamen | En trunkeret l1-protein af human papillomavirus 6 |
WO2009092113A2 (en) * | 2008-01-19 | 2009-07-23 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for the delivery of vaccines to disrupted epithelium |
CN102099053A (zh) | 2008-05-26 | 2011-06-15 | 卡迪拉保健有限公司 | 麻疹-人乳头瘤组合疫苗 |
GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
GB0820822D0 (en) | 2008-11-13 | 2008-12-24 | Inst Catala D Oncologia | Novel product and processes |
WO2010112533A1 (en) * | 2009-04-03 | 2010-10-07 | Deutsches Krebsforschungszentrum | Enhanced production of papillomavirus-like particles with a modified baculovirus expression system |
EP2437753B1 (de) | 2009-06-05 | 2016-08-31 | Infectious Disease Research Institute | Synthetische glucopyranosyl-lipid-adjuvanzien und impfstoffzusammensetzungen die diese enthalten |
WO2011026111A1 (en) | 2009-08-31 | 2011-03-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Oral delivery of a vaccine to the large intestine to induce mucosal immunity |
CA2795403C (en) | 2010-04-08 | 2019-01-15 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | B-cell antigen presenting cell assay |
US9044420B2 (en) | 2011-04-08 | 2015-06-02 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
US11510875B2 (en) | 2012-02-07 | 2022-11-29 | Access To Advanced Health Institute | Adjuvant formulations comprising TLR4 agonists and methods of using the same |
BR112014023092A8 (pt) | 2012-03-18 | 2017-07-25 | Glaxosmithkline Biologicals Sa | Composição imunogênica, método para a prevenção de infecção ou doença por hpv em um indivíduo, e, kit |
EP3388835B1 (de) | 2012-05-16 | 2020-04-01 | Immune Design Corp. | Impfstoffe gegen hsv-2 |
JP6430949B2 (ja) | 2012-10-23 | 2018-11-28 | エモリー ユニバーシティ | Gm−csfとil−4のコンジュゲート、組成物、ならびにそれに関連する方法 |
US8957047B2 (en) | 2013-04-18 | 2015-02-17 | Immune Design Corp. | GLA monotherapy for use in cancer treatment |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
AU2014373928C1 (en) | 2013-12-31 | 2020-12-17 | Access To Advanced Health Institute | Single vial vaccine formulations |
EP3420355A1 (de) | 2016-02-22 | 2019-01-02 | Boehringer Ingelheim Vetmedica GmbH | Verfahren zur immobilisierung von biomolekülen |
HUE059605T2 (hu) | 2016-05-16 | 2022-11-28 | Access To Advanced Health Inst | TLR agonista tartalmú készítmény és használati eljárások |
MX2018013640A (es) | 2016-05-16 | 2019-08-01 | Infectious Disease Res Inst | Liposomas pegiladas y metodos de uso. |
US11173126B2 (en) | 2016-06-01 | 2021-11-16 | Infectious Disease Research Institute | Nanoalum particles comprising a PAA sizing agent |
EP3638207A1 (de) | 2017-06-15 | 2020-04-22 | Infectious Disease Research Institute | Nanostrukturierte lipidträger sowie stabile emulsionen und ihre verwendung |
AU2018330165A1 (en) | 2017-09-08 | 2020-04-02 | Access To Advanced Health Institute | Liposomal formulations comprising saponin and methods of use |
KR20220125149A (ko) | 2019-05-25 | 2022-09-14 | 액세스 투 어드밴스드 헬스 인스티튜트 | 애주번트 백신 에멀션을 분무 건조시키기 위한 조성물 및 방법 |
AU2021337493A1 (en) | 2020-09-04 | 2023-05-18 | Access To Advanced Health Institute | Co-lyophilized rna and nanostructured lipid carrier |
CA3210363A1 (en) | 2021-02-11 | 2022-08-18 | Glaxosmithkline Biologicals Sa | Hpv vaccine manufacture |
WO2024052882A1 (en) | 2022-09-09 | 2024-03-14 | Access To Advanced Health Institute | Immunogenic vaccine composition incorporating a saponin |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4956288A (en) * | 1988-04-22 | 1990-09-11 | Biogen, Inc. | Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA |
NZ232913A (en) | 1989-03-15 | 1992-08-26 | Gist Brocades Nv | Il-3 produced recombinantly and purified to homogeneity; vectors and pharmaceutical preparations |
DE122007000018I1 (de) * | 1991-07-19 | 2007-05-24 | Univ Queensland | Polynukleotidabschnitt des HPV16-Genoms |
-
1994
- 1994-03-08 PT PT05075369T patent/PT1618888E/pt unknown
- 1994-03-08 EP EP05075369A patent/EP1618888B1/de not_active Expired - Lifetime
- 1994-03-08 PT PT94912186T patent/PT688227E/pt unknown
- 1994-03-08 EP EP94912186A patent/EP0688227B1/de not_active Expired - Lifetime
- 1994-03-08 DK DK05075369.8T patent/DK1618888T3/da active
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- 1994-03-08 DE DE69435332T patent/DE69435332D1/de not_active Expired - Lifetime
- 1994-03-08 DE DE69434383T patent/DE69434383T2/de not_active Expired - Lifetime
- 1994-03-08 EP EP05075889A patent/EP1588713B1/de not_active Expired - Lifetime
- 1994-03-08 DE DE201112100018 patent/DE122011100018I1/de active Pending
- 1994-03-08 AU AU64436/94A patent/AU688759C/en not_active Expired
- 1994-03-08 DE DE69435331T patent/DE69435331D1/de not_active Expired - Lifetime
- 1994-03-08 AT AT94912186T patent/ATE296111T1/de active
- 1994-03-08 DE DE1994634383 patent/DE122007000014I1/de active Pending
- 1994-03-08 CA CA2157932A patent/CA2157932C/en not_active Expired - Lifetime
- 1994-03-08 DK DK94912186T patent/DK0688227T3/da active
- 1994-03-08 DE DE122007000090C patent/DE122007000090I1/de active Pending
- 1994-03-08 AT AT05075369T patent/ATE494005T1/de active
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- 1994-03-08 ES ES05075889T patent/ES2263406T3/es not_active Expired - Lifetime
- 1994-03-08 DE DE05075369T patent/DE05075369T1/de active Pending
- 1994-03-08 JP JP6520236A patent/JPH08507685A/ja not_active Withdrawn
- 1994-03-08 DE DE122007000089C patent/DE122007000089I1/de active Pending
- 1994-03-08 DE DE05075889T patent/DE05075889T1/de active Pending
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- 1994-03-08 WO PCT/US1994/002443 patent/WO1994020137A1/en active IP Right Grant
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2006
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2007
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- 2007-03-07 AU AU2007201006A patent/AU2007201006B2/en not_active Expired
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2010
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2011
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