DE69435332D1 - Herstellung von menschlichem Papillomaviren Hüllprotein und Virus-ähnlichen Teilchen - Google Patents

Herstellung von menschlichem Papillomaviren Hüllprotein und Virus-ähnlichen Teilchen

Info

Publication number
DE69435332D1
DE69435332D1 DE69435332T DE69435332T DE69435332D1 DE 69435332 D1 DE69435332 D1 DE 69435332D1 DE 69435332 T DE69435332 T DE 69435332T DE 69435332 T DE69435332 T DE 69435332T DE 69435332 D1 DE69435332 D1 DE 69435332D1
Authority
DE
Germany
Prior art keywords
virus
particles
preparation
envelope protein
human papillomavirus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69435332T
Other languages
English (en)
Inventor
Robert C Rose
William Bonnez
Richard C Reichman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Rochester
Original Assignee
University of Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26703787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69435332(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/028,517 external-priority patent/US8062642B1/en
Application filed by University of Rochester filed Critical University of Rochester
Application granted granted Critical
Publication of DE69435332D1 publication Critical patent/DE69435332D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69435332T 1993-03-09 1994-03-08 Herstellung von menschlichem Papillomaviren Hüllprotein und Virus-ähnlichen Teilchen Expired - Lifetime DE69435332D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/028,517 US8062642B1 (en) 1993-03-09 1993-03-09 Production of papillomavirus capsid protein and virus-like particles
US20730994A 1994-03-07 1994-03-07

Publications (1)

Publication Number Publication Date
DE69435332D1 true DE69435332D1 (de) 2011-02-17

Family

ID=26703787

Family Applications (9)

Application Number Title Priority Date Filing Date
DE69435332T Expired - Lifetime DE69435332D1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papillomaviren Hüllprotein und Virus-ähnlichen Teilchen
DE201112100018 Pending DE122011100018I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusahnlichen Teilchen.
DE69435331T Expired - Lifetime DE69435331D1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichen papillomavirus HBV-11 Kapsidprotein L1 und Virus-ähnliche Partikeln
DE05075369T Pending DE05075369T1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusähnlichen Teilchen
DE69434383T Expired - Lifetime DE69434383T2 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
DE05075889T Pending DE05075889T1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papilloma-Virus HBV-11-Capsid-Protein L1 und virusähnlichen Teilchen
DE122007000089C Pending DE122007000089I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
DE1994634383 Pending DE122007000014I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papillomavirus Hüllprotein und virus-ähnlichen Teilchen
DE122007000090C Pending DE122007000090I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen

Family Applications After (8)

Application Number Title Priority Date Filing Date
DE201112100018 Pending DE122011100018I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusahnlichen Teilchen.
DE69435331T Expired - Lifetime DE69435331D1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichen papillomavirus HBV-11 Kapsidprotein L1 und Virus-ähnliche Partikeln
DE05075369T Pending DE05075369T1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papilloma-Virus-Capsid-Protein und virusähnlichen Teilchen
DE69434383T Expired - Lifetime DE69434383T2 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
DE05075889T Pending DE05075889T1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papilloma-Virus HBV-11-Capsid-Protein L1 und virusähnlichen Teilchen
DE122007000089C Pending DE122007000089I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
DE1994634383 Pending DE122007000014I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem Papillomavirus Hüllprotein und virus-ähnlichen Teilchen
DE122007000090C Pending DE122007000090I1 (de) 1993-03-09 1994-03-08 Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen

Country Status (14)

Country Link
EP (3) EP1588713B1 (de)
JP (4) JPH08507685A (de)
AT (3) ATE296111T1 (de)
AU (3) AU688759C (de)
CA (1) CA2157932C (de)
DE (9) DE69435332D1 (de)
DK (2) DK1618888T3 (de)
ES (3) ES2263406T3 (de)
FR (1) FR11C0022I2 (de)
HK (2) HK1082196A1 (de)
LU (3) LU91313I2 (de)
NL (3) NL300265I2 (de)
PT (2) PT1618888E (de)
WO (1) WO1994020137A1 (de)

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DE122007000089I1 (de) 2008-03-27
AU2007201006A1 (en) 2007-03-29
ES2263405T3 (es) 2011-04-20
DE122007000090I1 (de) 2008-03-27
NL300309I1 (nl) 2008-02-01
LU91313I2 (fr) 2007-04-23
AU2007201005A1 (en) 2007-03-29
NL300310I1 (nl) 2008-02-01
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AU2007201006B2 (en) 2010-07-01
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LU91392I2 (fr) 2008-02-14
LU91391I2 (fr) 2008-02-14
DE05075889T1 (de) 2006-10-05
NL300309I2 (nl) 2008-03-03
NL300265I2 (nl) 2008-05-01
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AU2007201005B2 (en) 2010-06-10
AU688759C (en) 2006-12-21
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HK1082206A1 (en) 2006-06-02
EP1588713B1 (de) 2010-12-22
HK1082196A1 (en) 2006-06-02
EP0688227A4 (de) 1996-05-29
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DK1618888T3 (da) 2011-04-04
EP0688227B1 (de) 2005-05-25
EP1618888B1 (de) 2011-01-05
DE69435331D1 (de) 2011-02-03
DE69434383D1 (de) 2005-06-30
DK0688227T3 (da) 2005-06-27
ES2263405T1 (es) 2006-12-16
ES2263406T1 (es) 2006-12-16
JP5386392B2 (ja) 2014-01-15
AU688759B2 (en) 1998-03-19
DE69434383T2 (de) 2005-11-24
JP2010099091A (ja) 2010-05-06
EP1618888A1 (de) 2006-01-25
JPH08507685A (ja) 1996-08-20
PT1618888E (pt) 2011-04-08
ATE494005T1 (de) 2011-01-15
AU6443694A (en) 1994-09-26
ATE492289T1 (de) 2011-01-15
CA2157932C (en) 2011-10-11
FR11C0022I1 (de) 2011-05-08
JP4486075B2 (ja) 2010-06-23
EP0688227A1 (de) 1995-12-27
ATE296111T1 (de) 2005-06-15
JP5306251B2 (ja) 2013-10-02
DE05075369T1 (de) 2006-11-16
CA2157932A1 (en) 1994-09-15
ES2263406T3 (es) 2011-06-06
PT688227E (pt) 2005-10-31
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