CN1089469A - 用于持续释放药物的传送装置的二相基材 - Google Patents

用于持续释放药物的传送装置的二相基材 Download PDF

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Publication number
CN1089469A
CN1089469A CN93118244A CN93118244A CN1089469A CN 1089469 A CN1089469 A CN 1089469A CN 93118244 A CN93118244 A CN 93118244A CN 93118244 A CN93118244 A CN 93118244A CN 1089469 A CN1089469 A CN 1089469A
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base material
medicine
pharmaceutical formulation
release pharmaceutical
phase
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CN93118244A
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English (en)
Chinese (zh)
Inventor
许宗民
陈栋奋
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Cygnus Therapeutic Systems
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Cygnus Therapeutic Systems
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Publication of CN1089469A publication Critical patent/CN1089469A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN93118244A 1992-10-05 1993-10-05 用于持续释放药物的传送装置的二相基材 Pending CN1089469A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95663592A 1992-10-05 1992-10-05
US956,635 1992-10-05
US056,076 1993-04-30
US08/056,076 US5989586A (en) 1992-10-05 1993-04-30 Two-phase matrix for sustained release drug delivery device

Publications (1)

Publication Number Publication Date
CN1089469A true CN1089469A (zh) 1994-07-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN93118244A Pending CN1089469A (zh) 1992-10-05 1993-10-05 用于持续释放药物的传送装置的二相基材

Country Status (14)

Country Link
US (2) US5989586A (enExample)
EP (1) EP0662822B1 (enExample)
JP (1) JPH08504757A (enExample)
CN (1) CN1089469A (enExample)
AT (1) ATE198420T1 (enExample)
AU (1) AU5321194A (enExample)
CA (1) CA2145631C (enExample)
DE (1) DE69329825T2 (enExample)
DK (1) DK0662822T3 (enExample)
ES (1) ES2155073T3 (enExample)
GR (1) GR3035626T3 (enExample)
PT (1) PT662822E (enExample)
TW (1) TW252919B (enExample)
WO (1) WO1994007468A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100457095C (zh) * 2001-05-08 2009-02-04 施瓦茨制药有限公司 用于治疗帕金森氏病的改良经皮治疗系统
CN100558350C (zh) * 2002-07-30 2009-11-11 施瓦茨制药有限公司 改良透皮递药系统
CN102172351B (zh) * 2001-05-08 2013-07-17 优时比制药有限公司 引起高罗替高汀血浆水平的用于治疗帕金森氏病的透皮治疗系统

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CN100558350C (zh) * 2002-07-30 2009-11-11 施瓦茨制药有限公司 改良透皮递药系统

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US5840336A (en) 1998-11-24
CA2145631C (en) 2004-02-10
DE69329825D1 (de) 2001-02-08
EP0662822A1 (en) 1995-07-19
ATE198420T1 (de) 2001-01-15
CA2145631A1 (en) 1994-04-14
WO1994007468A1 (en) 1994-04-14
JPH08504757A (ja) 1996-05-21
EP0662822A4 (en) 1996-08-07
DK0662822T3 (da) 2001-01-29
GR3035626T3 (en) 2001-06-29
DE69329825T2 (de) 2001-06-13
US5989586A (en) 1999-11-23
ES2155073T3 (es) 2001-05-01
PT662822E (pt) 2001-04-30
AU5321194A (en) 1994-04-26
TW252919B (enExample) 1995-08-01
EP0662822B1 (en) 2001-01-03

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