CN108472309A - 用于水痘带状疱疹病毒（vzv）的核酸疫苗 - Google Patents

用于水痘带状疱疹病毒（vzv）的核酸疫苗 Download PDF

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CN108472309A
CN108472309A CN201680075063.0A CN201680075063A CN108472309A CN 108472309 A CN108472309 A CN 108472309A CN 201680075063 A CN201680075063 A CN 201680075063A CN 108472309 A CN108472309 A CN 108472309A
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vzv
vaccine
rna
seq
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朱塞佩·恰拉梅拉
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ModernaTx Inc
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ModernaTx Inc
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Priority to CN202311460134.7A priority Critical patent/CN117731769A/zh
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/25—Varicella-zoster virus
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    • A61K9/5123—Organic compounds, e.g. fats, sugars
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    • A61P31/12—Antivirals
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
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    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16771—Demonstrated in vivo effect
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CN201680075063.0A 2015-10-22 2016-10-21 用于水痘带状疱疹病毒（vzv）的核酸疫苗 Pending CN108472309A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311460134.7A CN117731769A (zh) 2015-10-22 2016-10-21 用于水痘带状疱疹病毒(vzv)的核酸疫苗

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562245031P 2015-10-22 2015-10-22
US201562245234P 2015-10-22 2015-10-22
US62/245,031 2015-10-22
US62/245,234 2015-10-22
US201562247697P 2015-10-28 2015-10-28
US62/247,697 2015-10-28
US201662335348P 2016-05-12 2016-05-12
US62/335,348 2016-05-12
PCT/US2016/058297 WO2017070601A1 (en) 2015-10-22 2016-10-21 Nucleic acid vaccines for varicella zoster virus (vzv)

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CN202311460134.7A Division CN117731769A (zh) 2015-10-22 2016-10-21 用于水痘带状疱疹病毒(vzv)的核酸疫苗

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CN108472309A true CN108472309A (zh) 2018-08-31

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CN202311460134.7A Pending CN117731769A (zh) 2015-10-22 2016-10-21 用于水痘带状疱疹病毒(vzv)的核酸疫苗

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US (4) US11643441B1 (https=)
EP (1) EP3364980A4 (https=)
JP (4) JP6925688B2 (https=)
KR (1) KR20180094859A (https=)
CN (2) CN108472309A (https=)
AU (2) AU2016342371B2 (https=)
BR (1) BR112018008051A2 (https=)
CA (1) CA3002912A1 (https=)
CL (1) CL2018001051A1 (https=)
CO (1) CO2018005265A2 (https=)
EA (1) EA201891001A1 (https=)
IL (1) IL258827A (https=)
MA (1) MA46080A (https=)
MX (1) MX2018004915A (https=)
PE (1) PE20181529A1 (https=)
PH (1) PH12018500858A1 (https=)
SG (1) SG11201803360UA (https=)
TN (1) TN2018000152A1 (https=)
TW (1) TW201729838A (https=)
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Cited By (27)

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CN109602901A (zh) * 2019-01-08 2019-04-12 成都迈科康生物科技有限公司 一种带状疱疹病毒疫苗及其制备方法和应用
CN111840538A (zh) * 2020-05-29 2020-10-30 中山大学 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用
CN112142829A (zh) * 2019-06-28 2020-12-29 怡道生物科技(苏州)有限公司 水痘-带状疱疹病毒gE蛋白突变体及其表达方法
WO2020259609A1 (zh) * 2019-06-28 2020-12-30 怡道生物科技(苏州)有限公司 一种重组带状疱疹疫苗组合物及其用途
CN112386688A (zh) * 2021-01-20 2021-02-23 北京欣颂生物科技有限公司 一种用于病毒治疗的含有免疫细胞的药物组合物
WO2021103434A1 (zh) * 2019-11-29 2021-06-03 北京绿竹生物技术股份有限公司 一种重组水痘带状疱疹病毒疫苗
CN113045670A (zh) * 2019-12-27 2021-06-29 华南农业大学 一种可溶性鸡α干扰素融合蛋白及其生产方法与应用
CN113144186A (zh) * 2021-02-09 2021-07-23 中国医学科学院医学生物学研究所 一种水痘-带状疱疹疫苗组合物及其制备方法和应用
CN113372453A (zh) * 2021-06-11 2021-09-10 湖南兀邦生物科技有限公司 一种融合蛋白及猪流行性腹泻病毒s1蛋白重组亚单位疫苗
CN114081943A (zh) * 2021-11-08 2022-02-25 中国医学科学院医学生物学研究所 一种水痘-带状疱疹mRNA疫苗组合物及其制备方法和应用
CN116023510A (zh) * 2022-12-01 2023-04-28 北京吉诺卫生物科技有限公司 双佐剂重组带状疱疹疫苗
CN116355917A (zh) * 2023-02-15 2023-06-30 上海臻上医药科技有限公司 一种水痘-带状疱疹病毒mRNA疫苗及其应用
CN116474086A (zh) * 2022-11-24 2023-07-25 中国药科大学 一种预防和/或治疗带状疱疹病的疫苗试剂
WO2023179588A1 (zh) * 2022-03-21 2023-09-28 厦门大学 截短的水痘-带状疱疹病毒囊膜糖蛋白gE
WO2024051266A1 (zh) * 2022-09-07 2024-03-14 远大赛威信生命科学(南京)有限公司 用于表达水痘-带状疱疹病毒抗原蛋白的mRNA及其用途
CN118240844A (zh) * 2024-05-27 2024-06-25 北京悦康科创医药科技股份有限公司 带状疱疹mRNA疫苗及其制备方法和应用
WO2024153235A1 (zh) * 2023-01-19 2024-07-25 厦门大学 一种水痘-带状疱疹病毒gE和gI的融合蛋白及应用
WO2024179043A1 (zh) * 2023-02-28 2024-09-06 易慧生物技术(上海)有限公司 一种截短型水痘-带状疱疹病毒gE蛋白及其应用
CN118955655A (zh) * 2023-12-21 2024-11-15 北京微星生物科技有限公司 一种gE蛋白抗原变体、制备方法及其应用
WO2025002359A1 (zh) * 2023-06-30 2025-01-02 深圳深信生物科技有限公司 水痘带状疱疹病毒(vzv)疫苗
WO2025002352A1 (zh) * 2023-06-28 2025-01-02 上海瑞宏迪医药有限公司 一种含有阳离子脂质的药物组合物及其用途
CN119587687A (zh) * 2023-09-28 2025-03-11 珠海丽凡达生物技术有限公司 水痘带状疱疹病毒疫苗及其制备方法和应用
CN119746054A (zh) * 2023-09-28 2025-04-04 珠海丽凡达生物技术有限公司 水痘带状疱疹病毒疫苗及其制备方法和应用
CN119746053A (zh) * 2023-09-28 2025-04-04 珠海丽凡达生物技术有限公司 水痘带状疱疹病毒疫苗及其制备方法和应用
WO2025108306A1 (zh) * 2023-11-20 2025-05-30 上海蓝鹊生物医药有限公司 一种vzv抗原变体、核酸、药物组合物及其应用
WO2025236842A1 (zh) * 2024-05-13 2025-11-20 普大生物科技(泰州)有限公司 一种vzv重组蛋白及其制备方法和应用
WO2026037422A1 (zh) * 2024-08-16 2026-02-19 广州市恒诺康医药科技有限公司 一种预防水痘带状疱疹的mRNA疫苗及其制备方法和应用

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JP7330590B2 (ja) 2023-08-22
CL2018001051A1 (es) 2018-10-19
JP2023116608A (ja) 2023-08-22
EP3364980A1 (en) 2018-08-29
EA201891001A1 (ru) 2018-11-30
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IL258827A (en) 2018-06-28
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Application publication date: 20180831