CN108048573A - 用于确定癌症对象之预后的方法和核酸 - Google Patents

用于确定癌症对象之预后的方法和核酸 Download PDF

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Publication number
CN108048573A
CN108048573A CN201810020458.1A CN201810020458A CN108048573A CN 108048573 A CN108048573 A CN 108048573A CN 201810020458 A CN201810020458 A CN 201810020458A CN 108048573 A CN108048573 A CN 108048573A
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cancer
treatment
sequence
methylated
subject
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约恩·莱温
曼纽尔·克里斯平
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Epigenomics AG
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Epigenomics AG
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201810020458.1A 2011-07-08 2012-07-09 用于确定癌症对象之预后的方法和核酸 Pending CN108048573A (zh)

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US201161505919P 2011-07-08 2011-07-08
US61/505,919 2011-07-08
CN201280033813.XA CN103732759A (zh) 2011-07-08 2012-07-09 用于确定癌症对象之预后的方法和核酸

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CN201280033813.XA Pending CN103732759A (zh) 2011-07-08 2012-07-09 用于确定癌症对象之预后的方法和核酸

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US (4) US10626462B2 (https=)
EP (1) EP2729579B1 (https=)
JP (1) JP6397762B2 (https=)
KR (1) KR102046668B1 (https=)
CN (2) CN108048573A (https=)
AU (1) AU2012282528B2 (https=)
BR (1) BR112014000443B1 (https=)
CA (1) CA2840149C (https=)
DK (1) DK2729579T3 (https=)
EA (1) EA034232B1 (https=)
ES (1) ES2654561T3 (https=)
HR (1) HRP20180001T1 (https=)
HU (1) HUE036036T2 (https=)
IL (1) IL230303B (https=)
LT (1) LT2729579T (https=)
MX (1) MX358117B (https=)
NO (1) NO2729579T3 (https=)
PH (1) PH12014500063A1 (https=)
SI (1) SI2729579T1 (https=)
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CN114561452A (zh) * 2022-03-10 2022-05-31 天津市人民医院 mSEPT9作为预测结直肠癌患者术后复发风险标志物及用于评价化疗方案有效性的应用
CN115029462A (zh) * 2022-08-10 2022-09-09 中国农业科学院农业质量标准与检测技术研究所 一种动植物疫病的核酸标准物质、形貌模拟方法及其应用

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CN104745575B (zh) * 2014-08-08 2019-03-12 博诚研究中心 用于检测细胞增殖性异常或疾病程度分级的基因组合物及其用途
EP3766986B1 (en) 2014-12-31 2022-06-01 Guardant Health, Inc. Detection and treatment of disease exhibiting disease cell heterogeneity and systems and methods for communicating test results
CN106148501A (zh) * 2015-04-23 2016-11-23 博诚研究中心 一种检测Septin9基因甲基化的试剂盒及其应用
US20180187246A1 (en) * 2015-07-15 2018-07-05 Universiteit Gent Probes and a methylation in situ hybridization assay
JP6897970B2 (ja) * 2015-09-08 2021-07-07 国立大学法人山口大学 大腸腫瘍の有無を検査する方法
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WO2018195217A1 (en) 2017-04-19 2018-10-25 Singlera Genomics, Inc. Compositions and methods for library construction and sequence analysis
CN107385056A (zh) * 2017-08-10 2017-11-24 上海时代基因医学科技有限公司 一种检测SEPT9基因不同Cpg岛甲基化的试剂盒及应用
WO2019076949A1 (en) * 2017-10-18 2019-04-25 Deutsches Krebsforschungszentrum MEANS AND METHODS FOR CLASSIFYING COLORECTAL CANCERS
WO2019108568A1 (en) * 2017-11-29 2019-06-06 The Regents Of The University Of Michigan Compositions and methods for characterizing cancer
CN108796080B (zh) * 2018-06-06 2022-06-07 苏州唯善生物科技有限公司 用于结直肠癌诊断、检测或筛查的引物和探针组
CN109055552A (zh) * 2018-08-23 2018-12-21 北京迈基诺基因科技股份有限公司 检测Septin9基因启动子是否甲基化的方法及其专用成套试剂
CN112195243A (zh) * 2020-09-22 2021-01-08 北京华大吉比爱生物技术有限公司 一种检测多基因甲基化的试剂盒及其应用
KR102404750B1 (ko) 2021-10-14 2022-06-07 주식회사 엔도믹스 세포 유리 dna를 이용한 대장암 진단을 위한 메틸화 마커 유전자 및 이의 용도
KR102559496B1 (ko) * 2022-04-26 2023-07-25 연세대학교 산학협력단 핵산의 메틸화 여부 확인용 조성물 및 핵산의 메틸화 여부를 확인하는 방법
CN115248313A (zh) * 2022-08-03 2022-10-28 中山市人民医院 肠癌外周血免疫细胞m5C标志物的应用
CA3268032A1 (en) * 2022-09-23 2024-03-28 Flagship Pioneering Innovations Vi, Llc NUCLEIC ACID AMPLIFICATION PROCESSES
WO2024107441A1 (en) * 2022-11-14 2024-05-23 Trustees Of Dartmouth College Systemic biomarkers for the dynamic assessment of tumor burden and treatment efficacy in high grade gliomas

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114561452A (zh) * 2022-03-10 2022-05-31 天津市人民医院 mSEPT9作为预测结直肠癌患者术后复发风险标志物及用于评价化疗方案有效性的应用
CN115029462A (zh) * 2022-08-10 2022-09-09 中国农业科学院农业质量标准与检测技术研究所 一种动植物疫病的核酸标准物质、形貌模拟方法及其应用

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US20150031021A1 (en) 2015-01-29
MX2014000116A (es) 2014-03-27
US12110558B2 (en) 2024-10-08
EA201400117A1 (ru) 2014-06-30
JP6397762B2 (ja) 2018-09-26
CA2840149C (en) 2021-10-26
ES2654561T3 (es) 2018-02-14
MX358117B (es) 2018-08-06
HUE036036T2 (hu) 2018-06-28
US20200308656A1 (en) 2020-10-01
HRP20180001T1 (hr) 2018-03-09
KR102046668B1 (ko) 2019-11-19
ZA201400089B (en) 2022-03-30
BR112014000443B1 (pt) 2021-03-23
EA034232B1 (ru) 2020-01-20
CA2840149A1 (en) 2013-01-17
SI2729579T1 (en) 2018-07-31
IL230303B (en) 2018-05-31
AU2012282528B2 (en) 2017-04-13
CN103732759A (zh) 2014-04-16
US11261499B2 (en) 2022-03-01
EP2729579A1 (en) 2014-05-14
NO2729579T3 (https=) 2018-03-03
WO2013007702A1 (en) 2013-01-17
DK2729579T3 (en) 2018-01-08
JP2014520520A (ja) 2014-08-25
LT2729579T (lt) 2018-02-26
US20250101527A1 (en) 2025-03-27
KR20140044385A (ko) 2014-04-14
US10626462B2 (en) 2020-04-21
EP2729579B1 (en) 2017-10-04
PH12014500063A1 (en) 2014-02-17
US20220243277A1 (en) 2022-08-04
AU2012282528A1 (en) 2014-01-23
BR112014000443A2 (pt) 2017-02-14

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