BR112014000443B1 - Métodos para determinação do prognóstico de um indivíduo com câncer - Google Patents

Métodos para determinação do prognóstico de um indivíduo com câncer Download PDF

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Publication number
BR112014000443B1
BR112014000443B1 BR112014000443-9A BR112014000443A BR112014000443B1 BR 112014000443 B1 BR112014000443 B1 BR 112014000443B1 BR 112014000443 A BR112014000443 A BR 112014000443A BR 112014000443 B1 BR112014000443 B1 BR 112014000443B1
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cancer
treatment
methylated
individual
methylation
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BR112014000443-9A
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English (en)
Portuguese (pt)
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BR112014000443A2 (pt
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Joern Lewin
Manuel Krispin
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Epigenomics Ag
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Publication of BR112014000443B1 publication Critical patent/BR112014000443B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BR112014000443-9A 2011-07-08 2012-07-09 Métodos para determinação do prognóstico de um indivíduo com câncer BR112014000443B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161505919P 2011-07-08 2011-07-08
US61/505,919 2011-07-08
PCT/EP2012/063436 WO2013007702A1 (en) 2011-07-08 2012-07-09 Methods and nucleic acids for determining the prognosis of a cancer subject

Publications (2)

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BR112014000443A2 BR112014000443A2 (pt) 2017-02-14
BR112014000443B1 true BR112014000443B1 (pt) 2021-03-23

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BR112014000443-9A BR112014000443B1 (pt) 2011-07-08 2012-07-09 Métodos para determinação do prognóstico de um indivíduo com câncer

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US (4) US10626462B2 (https=)
EP (1) EP2729579B1 (https=)
JP (1) JP6397762B2 (https=)
KR (1) KR102046668B1 (https=)
CN (2) CN108048573A (https=)
AU (1) AU2012282528B2 (https=)
BR (1) BR112014000443B1 (https=)
CA (1) CA2840149C (https=)
DK (1) DK2729579T3 (https=)
EA (1) EA034232B1 (https=)
ES (1) ES2654561T3 (https=)
HR (1) HRP20180001T1 (https=)
HU (1) HUE036036T2 (https=)
IL (1) IL230303B (https=)
LT (1) LT2729579T (https=)
MX (1) MX358117B (https=)
NO (1) NO2729579T3 (https=)
PH (1) PH12014500063A1 (https=)
SI (1) SI2729579T1 (https=)
WO (1) WO2013007702A1 (https=)
ZA (1) ZA201400089B (https=)

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JP6897970B2 (ja) * 2015-09-08 2021-07-07 国立大学法人山口大学 大腸腫瘍の有無を検査する方法
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WO2019076949A1 (en) * 2017-10-18 2019-04-25 Deutsches Krebsforschungszentrum MEANS AND METHODS FOR CLASSIFYING COLORECTAL CANCERS
WO2019108568A1 (en) * 2017-11-29 2019-06-06 The Regents Of The University Of Michigan Compositions and methods for characterizing cancer
CN108796080B (zh) * 2018-06-06 2022-06-07 苏州唯善生物科技有限公司 用于结直肠癌诊断、检测或筛查的引物和探针组
CN109055552A (zh) * 2018-08-23 2018-12-21 北京迈基诺基因科技股份有限公司 检测Septin9基因启动子是否甲基化的方法及其专用成套试剂
CN112195243A (zh) * 2020-09-22 2021-01-08 北京华大吉比爱生物技术有限公司 一种检测多基因甲基化的试剂盒及其应用
KR102404750B1 (ko) 2021-10-14 2022-06-07 주식회사 엔도믹스 세포 유리 dna를 이용한 대장암 진단을 위한 메틸화 마커 유전자 및 이의 용도
CN114561452A (zh) * 2022-03-10 2022-05-31 天津市人民医院 mSEPT9作为预测结直肠癌患者术后复发风险标志物及用于评价化疗方案有效性的应用
KR102559496B1 (ko) * 2022-04-26 2023-07-25 연세대학교 산학협력단 핵산의 메틸화 여부 확인용 조성물 및 핵산의 메틸화 여부를 확인하는 방법
CN115248313A (zh) * 2022-08-03 2022-10-28 中山市人民医院 肠癌外周血免疫细胞m5C标志物的应用
CN115029462B (zh) * 2022-08-10 2022-11-08 中国农业科学院农业质量标准与检测技术研究所 一种动植物疫病的核酸标准物质、形貌模拟方法及其应用
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WO2024107441A1 (en) * 2022-11-14 2024-05-23 Trustees Of Dartmouth College Systemic biomarkers for the dynamic assessment of tumor burden and treatment efficacy in high grade gliomas

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Also Published As

Publication number Publication date
US20150031021A1 (en) 2015-01-29
MX2014000116A (es) 2014-03-27
US12110558B2 (en) 2024-10-08
EA201400117A1 (ru) 2014-06-30
JP6397762B2 (ja) 2018-09-26
CA2840149C (en) 2021-10-26
ES2654561T3 (es) 2018-02-14
MX358117B (es) 2018-08-06
HUE036036T2 (hu) 2018-06-28
US20200308656A1 (en) 2020-10-01
HRP20180001T1 (hr) 2018-03-09
KR102046668B1 (ko) 2019-11-19
ZA201400089B (en) 2022-03-30
EA034232B1 (ru) 2020-01-20
CA2840149A1 (en) 2013-01-17
SI2729579T1 (en) 2018-07-31
IL230303B (en) 2018-05-31
AU2012282528B2 (en) 2017-04-13
CN103732759A (zh) 2014-04-16
US11261499B2 (en) 2022-03-01
EP2729579A1 (en) 2014-05-14
NO2729579T3 (https=) 2018-03-03
WO2013007702A1 (en) 2013-01-17
DK2729579T3 (en) 2018-01-08
JP2014520520A (ja) 2014-08-25
LT2729579T (lt) 2018-02-26
US20250101527A1 (en) 2025-03-27
KR20140044385A (ko) 2014-04-14
US10626462B2 (en) 2020-04-21
CN108048573A (zh) 2018-05-18
EP2729579B1 (en) 2017-10-04
PH12014500063A1 (en) 2014-02-17
US20220243277A1 (en) 2022-08-04
AU2012282528A1 (en) 2014-01-23
BR112014000443A2 (pt) 2017-02-14

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