CN106954847A - Ferment probiotic composition with function of relaxing bowel, using and process preparation - Google Patents

Ferment probiotic composition with function of relaxing bowel, using and process preparation Download PDF

Info

Publication number
CN106954847A
CN106954847A CN201710199841.3A CN201710199841A CN106954847A CN 106954847 A CN106954847 A CN 106954847A CN 201710199841 A CN201710199841 A CN 201710199841A CN 106954847 A CN106954847 A CN 106954847A
Authority
CN
China
Prior art keywords
slurry
powder
function
ferment
probiotic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710199841.3A
Other languages
Chinese (zh)
Inventor
郭兆锋
吴雪晴
郑政东
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Able Biotechnology Co Ltd
Original Assignee
Guangzhou Able Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Able Biotechnology Co Ltd filed Critical Guangzhou Able Biotechnology Co Ltd
Priority to CN201710199841.3A priority Critical patent/CN106954847A/en
Publication of CN106954847A publication Critical patent/CN106954847A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention disclose a kind of ferment probiotic composition with function of relaxing bowel, using and process preparation, composition includes vegetables and fruits plant enzyme powder, probiotics and dietary fiber；It gives full play to the mutually coordinated effect of vegetables and fruits plant enzyme powder, probiotics, dietary fiber, effectively alleviates and treatment constipation, Constipation recurrence；Also there is regulating intestinal canal colony balance, suppress the generation of harmful bacteria and toxin, promote the breeding and growth of beneficial bacterium；Regulation and recovery gastrointestinal function, strengthen gastrointestinal peristalsis；Promote excrement, the discharge of toxin in enteron aisle；It can also promote to digest simultaneously, supplement other nutritional ingredients such as nucleotides, organic acid for human body, promote the absorption of vitamin and minerals, enhance metabolism, the effects such as improving physical function.

Description

Ferment probiotic composition with function of relaxing bowel, using and process preparation
Technical field
The present invention relates to field of functional food technology, a kind of ferment probiotics with function of relaxing bowel is referred in particular to Composition, using and process preparation.
Background technology
With the influence of the change of people's dietary structure, the quickening of rhythm of life, society and mental element, China's constipation The incidence of disease is in rising trend, and according to the difference of definition, the incidence of disease of constipation is from 3.4% to 27.2%, and part constipation is serious Person has had influence on quality of life, or even brings the diseases such as cancer.But constipation patient is generally constipation and worried, doctor can be seldom gone Institute goes to a doctor, and attention degree is relatively low.
Omnibus survey research display, constipation shows obvious ascendant trend with the increase at age, and China is old Total amount expansion, the developing state of increment speed-raising is presented in population size, with the arrival in aging population epoch, China constipation crowd More expand.The problem of actively resolving constipation, can not only make it that the elderly, from the hardship of constipation, increases the life matter of the elderly Amount, moreover it is possible to reduce the generation of constipation relevant disease is significant.
The teiology and Pathological Physiology of constipation are still unknown, and it is a kind of common complicated symptom of clinic, mainly Refer to that defecation frequency is reduced, feces volume is reduced, excrement is dry and hard, defecation is hard, defecation not only sense, there is no satisfied happy sense after defecation Etc..Constipation patient is generally also with symptoms such as insomnia, dreaminess, agitation, depression and anxiety.
From the point of view of the enteron aisle structure of human body, there are many bending and fold, second section colon and rectum inside our large intestine It is the place for being easiest to hoard residue stool, while the change of habits and customs make it that the functions of expelling toxin of body declines, external environment condition Change again cause more harmful substances enter in vivo formed toxin.The accumulation of intestines poison can form constipation, and constipation meeting More intestines poison are produced, intestines poison can damage neuron, cause nervous centralis to be damaged, each organ immunity degradation of body forms sub- Health.The toxin of stool still results in the arch-criminal of cancer, such as intestinal cancer, stomach cancer, cancer of the esophagus, liver cancer, breast cancer.Stool can make Obtain enteron aisle to narrow, constipation is aggravated, and is long thinked little of, will be caused intestinal cancer, intestinal cancer is occupied first of 21 century cancer.
At present, general life treatment, drug therapy, biofeedback training are had according to its different therapeutic scheme of the cause of disease of constipation And operative treatment.General life treatment be by adjusting life style, adjust mentality and appropriate motion gradually to recover defecation suitable Smooth state, can fundamentally mitigation capability constipation.Therapeutic scheme is divided into external preparation and oral preparations, and enema is just It is a kind of conventional external application purgatives, symptom after short-term relief symptom, deactivation can be played a part of and still have or even aggravate, taken stopgap measures Do not effect a permanent cure.Oral preparations are generally by the permeability for changing enteron aisle or use some irritating plant cathartics, such as rheum officinale, Folium sennae etc., reaches the purpose of defecation, but has the side effect for capturing catharsis more, the problems such as easily causing smooth amyotrophia, aggravates Constipation.For serious organic constipation patient more than biofeedback training or operative treatment, such as serious obstinate Colonic transit work( Can obstruction type constipation patient.
The narrow definition of ferment is enzyme, and it is indispensable with cytoactive that enzyme is that human body sustains life, and it is also cell weight The constituent wanted.The number of internal ferment activity decides the health status of people, " ferment how many, life is with regard to how many ". In fact, ferment as a kind of functional food in Japan and China Taiwan fashionable decades, it is with fresh Vegetable and fruit etc. is raw material, and the fermentation through microorganism generates substantial amounts of enzyme, amino acid, trace element, two second generations of bacterium Thank to the multiple nutritional components such as thing, can strengthen human body digests and assimilates function, build up resistance etc..
Probiotics is the class active microorganism beneficial to host, is colonized in human body intestinal canal, in reproductive system, can be produced really Health efficacy is cut so as to the active beneficial microorganism general name for improving host's microecological balance, playing beneficial effect.Microorganism is deposited It is multiple positions such as skin, oral cavity, nose, enteron aisle, the genitals of our human bodies, participates in multinomial physiological activity, such as nutrients The digestion of matter and absorption, generation vitamin, strengthen immunity etc., probiotics is healthy closely bound up with ours.Enteron aisle Tiny ecosystem is a beneficial bacterium and the Tiny ecosystem of harmful bacteria dynamic equilibrium, when harmful bacteria is dominant, can cause constipation, diarrhoea, The malaise symptoms such as stomachache, abdominal distension, and be conducive to the probiotics of intestinal health effectively to alleviate the symptom of upset,gastro-intestinal.But bacterial strain Difference, its stability and functional aberrancy are larger, the function and vigor of probiotics should the bacterial strain based on specific bacterial strain number carry out Research.
Increasing evidence is shown, can be obviously improved or treat constipation or the related disease of constipation by enteric microorganism Shape.Microorganism is changed in the enteron aisle of constipation patient, and the beneficial bacterium such as lactic acid bacteria, Bifidobacterium is reduced, and pseudomonas aeruginosa, The pathogenic bacteria such as campylobacter jejuni are increased, and the metabolism environment of enteron aisle changes, and have influence on Instestinal motility and secreting function etc..Volume The suitable probiotics preparation of outer supplement can recover environment, the generation of probiotics in the gut flora balance of constipation patient, regulation enteric cavity PH in chamber can also be reduced by thanking to thing, and change the sensitiveness and intestines peristalsis ability of enteron aisle, thus significantly improve or treat it is chronic just Secret and its related symptoms.
At present, also there are some patents of invention on ferment in China, there is that fermentation period is short, and raw material type is less, nutrition Not enough enrich, it is difficult to the problems such as extracting vegetables and fruits elite completely.Or will jointly be sent out after the raw materials such as tens kinds of vegetables and fruits directly mixing Ferment, because raw material type is more, parameter is difficult to control to, it is more difficult to realize scale quality stability.China is on the special of probiotics Benefit is for the solid beverage in terms of regulating intestinal canal flora or modulation milk powder.Patent of invention on ferment plus probiotics also refers to more Ferment product is made with probiotics fermention, probiotics can be removed in the sterilization process of product so that there was only ferment in finished product Function and the effect of probiotics can not be played.
Such as CN 106173613 is the ferment health products using probiotics fermention fruits and vegetables or cereal or integration of drinking and medicinal herbs, has been fermented It is degerming by membrane filtration after, obtain enzyme liquid.Products obtained therefrom only retains the active component of ferment, not active probiotic Effect.
Composite plant ferment containing profitable probliotics described in CN 103876155 is to utilize the bacillus of three saccharomycete one The raw material such as fermented cereal, vegetables and fruits, medicine-food two-purpose in four stages, obtains ferment fermentation liquid product, without active probiotic into Divide, only the active component of the metabolin of bacterium and ferment.
Described in CN 106174179 with effect of relaxing bowel enzyme composition be with sterilizing after Chinese medical extract and Enzyme stoste mixed liquor, is inoculated with spray drying after probiotics fermention and obtains, without the composition of active probiotic.
Plant enzyme probiotic powder described in CN 104489669 is that enzyme liquid first is made with microbial fermentation, spray-dried Obtain zymogen powder, then be well mixed with other auxiliary materials such as probiotic powder obtained.The patent is similar to this patent, but the patent exists Through high temperature spray-drying technique when preparing ferment, the vigor of the main functional component enzyme of ferment can be destroyed, is by all originals in addition Expect the fermentation that is mixed, zymotechnique is difficult to standardization control, it is difficult to realize big production.Probiotics described in the patent is also still The bacterial strain of the bacterial strain number of probiotics used, even same name is not pointed out, if bacterial strain difference, the function of the bacterial strain is stable The parameters such as property, survival rate are also not quite similar.
Ferment spray drying that CN 106173773 is obtained with probiotics fermention or it is lyophilized obtain vegetables and fruits plant enzyme powder, then by benefit Raw bacterium adds vacuum freeze drying after protective agent culture and obtains bacterium powder, adds mango powder, inulin, resistant dextrin, FOS system .The patent is similar to this patent, but ferment powder used is only made with 5 kinds of fruits and vegetables, not yet elaborates the preparation process of ferment, Selected raw material of the invention is more, and nutrition is more rich more balanced.In addition, the patent does not also do careful description and requirement to probiotics.
Generally speaking, the therapeutic scheme of relief of constipation is excessively stimulated again, and curative effect is fast but side effect is big, symptom after drug withdrawal It is even worse.Patents and mostly Chinese herbal compounds, Chinese prescription composition are then excessively complicated, and therapeutic effect relatively slow, mouthfeel is not It is good etc., and be difficult on the scheme of ferment probiotics while retaining both active components.Therefore a kind of healthy food is needed badly The problem of product prescription is to solve constipation.
The content of the invention
In view of this, in view of the existing deficiencies of the prior art, its main purpose is to provide a kind of logical with ease constipation the present invention Just the ferment probiotic composition of function, using and process preparation, it had both retained enzyme activity composition, and security is good, stability Good, energy regulating intestinal canal flora promotes digestion, enhancing physical function etc..
To achieve the above object, the present invention is using following technical scheme：
A kind of ferment probiotic composition with function of relaxing bowel, include vegetables and fruits plant enzyme powder, probiotics and Dietary fiber.
The vegetables and fruits plant enzyme powder is dried by 60 kinds of natural vegetables and fruits cereal and symbiosis probiotics after 540 days viable bacteria fermentations Grind and obtain.
The probiotics is selected from bifidobacterium longum, animal bifidobacteria, Lactobacillus helveticus, Lactobacillus rhamnosus, acidophilus breast One or more in bacillus, Lactobacillus plantarum, Lactobacillus casei and Bu Ladi yeast.
The dietary fiber is selected from water-soluble dietary fiber inulin, polydextrose, FOS, galactooligosaccharide, resistance One or more in dextrin, konjaku flour；Or Water insoluble dietary fiber common oats fibre, Semen Tritici aestivi fiber, zein fiber, soybean are fine One or more in the luxuriant isapgol husk of dimension, pea fibre, circle；Or the group of water-soluble dietary fiber and Water insoluble dietary fiber Close.
The mass ratio of the vegetables and fruits plant enzyme powder, probiotics and dietary fiber is (2~60)：(0~2)：(10~80).
It is preferred that, the preparation process of the vegetables and fruits plant enzyme powder is：Selected fresh mature, non-rot fruits and vegetables, paddy Thing is cleaned, section, osmotic pressure extractive fermentation, lactic acid deep-fermentation, acetic acid bacteria storage fermentation, afterripening fermentation, concentration, freezing Dry, grind and obtain；
Described fruits and vegetables include：Banana, tomato, apple, Kiwi berry, pachyrhizus, pineapple, grape, spinach, cabbage, asparagus, It is strawberry, lemon, orange, eggplant, wax gourd, pakchoi, guava, balsam pear, corn, lettuce, Sweet Potato Leaf, carambola, three-coloured amaranth, red sweet Sugarcane, sponge gourd, folium artemisiae argyi, wild cabbage, water-rich areas, grape fruit, crowndaisy chrysanthemum, watermelon, plum, asparagus, broccoli, cabbage mustard, passion fruit, cocoa Coconut, cumquat, leaf mustard, water spinach, wheat seedling, muskmelon, black fungus, cauliflower, green pepper, carrot, pumpkin, potato, plum, Wax-apple, cucumber, mushroom, cherry, blue or green river dish, taro, radish；
Described cereal includes：Black soya bean, soya bean, brown rice, mung bean.
The symbiosis probiotics includes saccharomycete, bacillus, lactic acid bacteria, acetic acid bacteria；
540 days described viable bacteria fermentations include four-stage, 180 days extractive fermentation phases, 210 days submerged fermentation phases, storage 90 days fermentation phases, 60 days maturity periods；
The equal single fermentation of described vegetables and fruits plant material is formed after the completion of 540 days according still further to certain ratio chelating；
The moisture requirement of described vegetables and fruits plant enzyme powder is less than 5%.
It is preferred that, the probiotics is Lactobacillus helveticus Rosell-0052, Lactobacillus plantarum Rosell-1012, long bifid Bacillus Rosell-0175, animal bifidobacteria LAFTI B94.
It is preferred that, the viable bacteria concentration of the probiotics is 1010Cfu/g~5 × 1011cfu/g。
It is preferred that, each bacterial strain percentage is Lactobacillus helveticus Rosell-0052 in the probiotics：Lactobacillus plantarum Rosell-1012：Bifidobacterium longum Rosell-0175：Animal bifidobacteria LAFTI B94=(10%~60%)：(8%~ 32%)：(2%~10%)：(30%~80%).
It is preferred that, the probiotics viable bacteria concentration in the composition is 104Cfu/g~1012Cfu/g, preferably 106cfu/ G~1011Cfu/g, preferred 108Cfu/g~1010cfu/g。
It is preferred that, the composition controls temperature at 18 DEG C~22 DEG C in preparation process, and humidity is 25%~35%.
It is preferred that, the dietary fiber is inulin, resistant dextrin.
It is preferred that, the mass ratio of the vegetables and fruits plant enzyme powder, probiotics and dietary fiber is (25~40)：(0.5~ 1.5)：(40~70).
A kind of application of the ferment probiotic composition with function of relaxing bowel, the foregoing ferment with function of relaxing bowel Application of the plain probiotic composition in the health products for preparing defaecation, alleviating or treating purgative function.
A kind of process preparation of the ferment probiotic composition with function of relaxing bowel, including Juice powder/slurry, sugar alcohol Class material, filler, flavouring and the foregoing ferment probiotic composition with function of relaxing bowel.
It is preferred that, the shared mass fraction of the ferment probiotic composition with function of relaxing bowel for 10%~ 60%.
It is preferred that, the Juice powder/slurry includes apple juice powder/slurry, grape juice powder/slurry, pineapple juice powder/slurry, lemon juice Powder/slurry, strawberry juice powder/slurry, orange juice powder/slurry, orange juice powder/slurry, grapefruit juice powder/slurry, mango juice powder/slurry, blueberry juice powder/ Slurry, Cranberry Juice Cocktail powder/slurry, cherry juice powder/slurry, Lychee juice powder/slurry, bananas juice powder/slurry, coconut milk powder/slurry, Cantaloupe juice powder/ Slurry, peach juice powder/slurry, kiwi-fruit juice powder/slurry, pear juice powder/slurry, juice of my pomegranate powder/slurry etc., jujube juice powder/slurry, oat juice powder/ One or more in slurry；
The glycitols material is in xylitol, antierythrite, D-sorbite, mannitol, maltitol, lactitol One or more；
One or more of the filler in maltodextrin, starch, microcrystalline cellulose, magnesium stearate；
The flavouring includes the one or more in sweetener, acid and essence；
The sweetener is selected from stevioside, Sucralose, Aspartame, acesulfame potassium, mogroside；Honey, high fructose corn One or more in slurry, honey, glucose or white granulated sugar；
One or more of the acid in citric acid, malic acid, lactic acid；
The essence is selected from the essence of corresponding fruit powder.
It is preferred that, the process preparation is solid powder, granule, capsule, oral liquid or tablet.
The present invention has clear advantage and beneficial effect compared with prior art, specifically, by above-mentioned technical proposal Understand：
Submerged fermentation in 540 days, depth extraction vegetables and fruits plant essence, and be fully retained the active component of ferment and nutrition into Point, effectively exclude stool and intestines poison；Selected high stability, high-activity probiotics bacterial strain, effective regulating intestinal canal colony balance improve Various enteron aisle malaise symptoms, and the repetition generation of energy Constipation；Inulin and resistant dextrin be both high-quality dietary fiber and Good prebiotics, can not only strengthen the wriggling ability of stomach, recover intestinal health, promote defecation, and especially some are practised Inertia constipation, intractable constipation has preferable improvement, can also promote the propagation of intestinal beneficial bacterium, suppresses pathogenic bacteria Deng.The present invention significantly, treats both principal and secondary aspect of disease, had no toxic side effect for constipation symptom therapeutic effect caused by a variety of causes, safe and reliable.
Embodiment
Present invention is disclosed a kind of ferment probiotic composition with function of relaxing bowel, include vegetables and fruits plant enzyme Powder, probiotics and dietary fiber；The vegetables and fruits plant enzyme powder is by 60 kinds of natural vegetables and fruits cereal and symbiosis probiotics through work in 540 days Bacterium fermentation after drying and grinding and obtain；The probiotics is selected from bifidobacterium longum, animal bifidobacteria, Lactobacillus helveticus, rhamnose One or more in lactobacillus, lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei and Bu Ladi yeast；The meals are fine Tie up one kind in water-soluble dietary fiber inulin, polydextrose, FOS, galactooligosaccharide, resistant dextrin, konjaku flour Or it is a variety of；Or the luxuriant car of Water insoluble dietary fiber common oats fibre, Semen Tritici aestivi fiber, zein fiber, soybean fiber, pea fibre, circle One or more in preceding sub- shell；Or the combination of water-soluble dietary fiber and Water insoluble dietary fiber.The vegetables and fruits plant ferment The mass ratio of plain powder, probiotics and dietary fiber is (2~60)：(0~2)：(10~80).
The preparation process of the vegetables and fruits plant enzyme powder is：Selected fresh mature, non-rot fruits and vegetables, cereal are through clear Wash, cut into slices, osmotic pressure extractive fermentation, lactic acid deep-fermentation, acetic acid bacteria storage fermentation, afterripening fermentation, concentration, freeze-drying, Grind and obtain；Described fruits and vegetables include：Banana, tomato, apple, Kiwi berry, pachyrhizus, pineapple, grape, spinach, cabbage, reed It is bamboo shoot, strawberry, lemon, orange, eggplant, wax gourd, pakchoi, guava, balsam pear, corn, lettuce, Sweet Potato Leaf, carambola, three-coloured amaranth, red Sugarcane, sponge gourd, folium artemisiae argyi, wild cabbage, water-rich areas, grape fruit, crowndaisy chrysanthemum, watermelon, plum, asparagus, broccoli, cabbage mustard, passion fruit, can Can coconut, cumquat, leaf mustard, water spinach, wheat seedling, muskmelon, black fungus, cauliflower, green pepper, carrot, pumpkin, potato, plum Son, wax-apple, cucumber, mushroom, cherry, blue or green river dish, taro, radish；Described cereal includes：Black soya bean, soya bean, brown rice, mung bean；Institute Stating symbiosis probiotics includes saccharomycete, bacillus, lactic acid bacteria, acetic acid bacteria；540 days described viable bacteria fermentations include four ranks Section, 180 days extractive fermentation phases, 210 days submerged fermentation phases, 90 days fermentation phases of storage, 60 days maturity periods；Described vegetables and fruits plant is former Equal single fermentation is expected after the completion of 540 days, is formed according still further to certain ratio chelating；The moisture of described vegetables and fruits plant enzyme powder contains Amount requires to be less than 5%.
The probiotics is Lactobacillus helveticus Rosell-0052, Lactobacillus plantarum Rosell-1012, bifidobacterium longum Rosell-0175, animal bifidobacteria LAFTI B94.By stomach juice-resistant and bile survival experiment, adhesion experiment, antibacterial reality Test, the external or authenticated high activity bacterial strain of in vivo studies.By the mutual synergy of this four plants of bacterium, on the one hand it can adjust The harmful bacterias such as gut flora balance, reduction pseudomonas aeruginosa, the campylobacter jejuni related to constipation is suppressed, and promote lactic acid The propagation of the intestinal beneficial bacteriums such as bacillus, Bifidobacterium.Improving the uncomfortable aspect of enteron aisle has obvious effect；On the one hand, it can pierce Swash the immunologic function of human body, prevent the growth of above-mentioned pathogenic bacteria；A variety of important bioactivators, such as short chain fat can also be produced Fat acid, can stimulate the power of ileum and colon, strengthen intestines peristalsis power.The viable bacteria concentration of the probiotics is 1010Cfu/g~5 ×1011cfu/g.Each bacterial strain percentage is Lactobacillus helveticus Rosell-0052 in the probiotics：Lactobacillus plantarum Rosell-1012：Bifidobacterium longum Rosell-0175：Animal bifidobacteria LAFTI B94=(10%~60%)：(8%~ 32%)：(2%~10%)：(30%~80%).Probiotics viable bacteria concentration in the composition is 104Cfu/g~ 1012Cfu/g, preferably 106Cfu/g~1011Cfu/g, preferred 108Cfu/g~1010cfu/g.It is prepared by the composition During control temperature at 18 DEG C~22 DEG C, humidity is 25%~35%.The dietary fiber is inulin, vegetable described in resistant dextrin The mass ratio of fruit plant enzyme powder, probiotics and dietary fiber is (25~40)：(0.5~1.5)：(40~70).
It is foregoing that there is profit present invention further teaches a kind of application of the ferment probiotic composition with function of relaxing bowel Application of the ferment probiotic composition of intestines bowel relaxing functions in the health products for preparing defaecation, alleviating or treating purgative function.
The present invention also disclosed a kind of process preparation of the ferment probiotic composition with function of relaxing bowel, including fruit Vegetable juice powder/slurry, glycitols material, filler, flavouring and the foregoing ferment probiotic composition with function of relaxing bowel. The shared mass fraction of the ferment probiotic composition with function of relaxing bowel is 10%~60%.The Juice Powder/slurry includes apple juice powder/slurry, grape juice powder/slurry, pineapple juice powder/slurry, lemon juice powder/slurry, strawberry juice powder/slurry, orange juice Powder/slurry, orange juice powder/slurry, grapefruit juice powder/slurry, mango juice powder/slurry, blueberry juice powder/slurry, Cranberry Juice Cocktail powder/slurry, cherry juice powder/ Slurry, Lychee juice powder/slurry, bananas juice powder/slurry, coconut milk powder/slurry, Cantaloupe juice powder/slurry, peach juice powder/slurry, kiwi-fruit juice One or more in powder/slurry, pear juice powder/slurry, juice of my pomegranate powder/slurry etc., jujube juice powder/slurry, oat juice powder/slurry；The sugar alcohol One or more of the class material in xylitol, antierythrite, D-sorbite, mannitol, maltitol, lactitol；Institute State one or more of the filler in maltodextrin, starch, microcrystalline cellulose, magnesium stearate；The flavouring includes sweet One or more in taste agent, acid and essence；The sweetener is selected from stevioside, Sucralose, Aspartame, An Sai Honey, mogroside；One or more in honey, fructose syrup, honey, glucose or white granulated sugar；The acid is selected from One or more in citric acid, malic acid, lactic acid；The essence is selected from the essence of corresponding fruit powder.The process preparation is Solid powder, granule, capsule, oral liquid or tablet.
Do further detailed to technical characteristic, implementation and the beneficial effect of the present invention with reference to specific implementation case Describe in detail bright, embodiments described below is only a part of embodiment of the present invention, and not all embodiment.In following embodiments The material unless otherwise noted, is common commercially available product, can all bought in market with reagent.
Wherein, vegetables and fruits plant enzyme powder is purchased from Taiwan big fellow group；
It is Lactobacillus helveticus Rosell-0052, Lactobacillus plantarum Rosell-1012, bifidobacterium longum Rosell-0175, dynamic Thing Bifidobacterium LAFTI B94 are purchased from Raman group；
Embodiment 1：
A kind of ferment probiotics solid beverage with function of relaxing bowel, is made up of the raw material of following parts by weight：
The ferment probiotics solid beverage with function of relaxing bowel, including following preparation process：By vegetables and fruits plant Fraction addition is abundant in proportion mixes for ferment powder, inulin, resistant dextrin, lactitol, Cranberry Juice Cocktail powder, then by Sucralose, lemon The method that lemon acid, probiotic powder are mixed according to gradient is well mixed, and the material mixed is dispensed with powder packing machine, packaging The product often wrapped into 5g, often bag ferment probiotics solid beverage dispatch from the factory viable count more than 1 × 1010CFU/ bags.It is required that production and processing Shi Wendu is 18 DEG C~22 DEG C, and humidity is 25%~35%.
Eating method：It is dissolved in 200mL warm water to take, is please eaten as early as possible after opening.
Embodiment 2：
A kind of ferment probiotics solid beverage with function of relaxing bowel, is made up of the raw material of following parts by weight：
The ferment probiotics solid beverage with function of relaxing bowel, including following preparation process：By vegetables and fruits plant Fraction addition is abundant in proportion mixes for ferment powder, inulin, resistant dextrin, lactitol, maltodextrin, strawberry juice powder, then by trichlorine The method that sucrose, citric acid, probiotic powder are mixed according to gradient is well mixed, and the material mixed is divided with powder packing machine Dress, is packaged into the product that 10g is often wrapped, and often bag ferment probiotics solid beverage dispatches from the factory viable count more than 6 × 109CFU/ bags.It is required that Temperature is 18 DEG C~22 DEG C during production and processing, and humidity is 25%~35%.
Eating method：It is dissolved in 200mL warm water and takes, is please eaten as early as possible after opening.
Embodiment 3：
A kind of ferment probiotics solid beverage with function of relaxing bowel, is made up of the raw material of following parts by weight：
The ferment probiotics solid beverage with function of relaxing bowel, including following preparation process：By vegetables and fruits plant The abundant mixing of fraction addition in proportion of ferment powder, inulin, resistant dextrin, lactitol, common oats fibre, konjaku flour, pineapple juice powder, then The method that Sucralose, citric acid, probiotic powder are mixed according to gradient is well mixed, the material powder packing machine mixed Dispensed, be packaged into the product that 8g is often wrapped, often bag ferment probiotics solid beverage dispatches from the factory viable count more than 7 × 109CFU/ bags. It is required that temperature is 18 DEG C~22 DEG C during production and processing, humidity is 25%~35%.
Eating method：It is dissolved in stirring evenly in 200mL warm water and takes, is please eaten as early as possible after opening.
Embodiment 4：
A kind of ferment probiotics solid tablet with function of relaxing bowel, is made up of the raw material of following parts by weight：
The ferment probiotics solid tablet with function of relaxing bowel, including following preparation process：By vegetables and fruits plant Ferment powder, inulin, resistant dextrin, xylitol, skimmed milk powder uniformly spray alcoholic solution, are pelletized with granulator, cross 20 mesh sieves, low Temperature drying, then by the abundant mixing of number addition in proportion of probiotic powder, microcrystalline cellulose, magnesium stearate, silica, then will system The particle and powder material got ready are well mixed, and 1g every product is pressed into tablet press machine, and bottling was both obtained, and every ferment is prebiotic The viable count that dispatches from the factory of bacterium solid tablet is more than 2 × 109CFU/.It is required that environment temperature is 18 DEG C~22 DEG C during production and processing, it is wet Degree is 25%~35%.
Eating method：Warm water is swallowed, and 1 to 2 tablets once, daily 1-3 times, and half an hour is edible before the meal.
Embodiment 5：
A kind of ferment probiotics capsule with function of relaxing bowel, is made up of the raw material of following parts by weight：
The ferment probiotics capsule with function of relaxing bowel, including following preparation process：By vegetables and fruits plant enzyme The abundant mixing of fraction addition in proportion of powder, inulin, resistant dextrin starch, then the method that probiotic powder is mixed according to gradient are mixed Uniformly, the material mixed is put into capsule filling machine and is filled, both 0.5g capsule, every ferment probiotics capsule goes out Factory's viable count is more than 4 × 109CFU/.It is required that temperature is 18 DEG C~22 DEG C during production and processing, humidity is 25%~35%.
Eating method：Warm water is swallowed, one every time, before the meal half an hour take, it is daily 1-3 times.
Embodiment 6：
A kind of ferment probiotics oral liquid with function of relaxing bowel, is made up of the raw material of following parts by weight：
The ferment probiotics oral liquid with function of relaxing bowel, including following preparation process：Xanthans is dissolved in In appropriate 80 DEG C of water, homogenizer homogeneous is crossed, then is well mixed with concentrated apple juice, honey, remaining water, by vegetables and fruits plant enzyme Powder, lactitol, inulin, resistant dextrin, which are dissolved in above-mentioned mixed liquor, to be well mixed, then logical retorted 20-30s, to be mixed Liquid is cooled to room temperature, adds probiotic powder and is well mixed, and mixes feed liquid and is carried out with bottle placer filling, had both obtained every bottle of 10mL Oral liquid, the viable count that dispatches from the factory of every bottle of ferment probiotics oral liquid is more than 2 × 109CFU/ bottles.
Eating method：Directly drink, one bottle every time, before the meal half an hour take, it is daily 1-3 times.
Animal model checking test：
Test method：Using ferment probiotics capsule of the embodiment 5 with function of relaxing bowel as test group, with toxin-expelling and face nourishing Soft capsule is control, suppresses model mice and Constipation Model to the small bowel peristalsis that normal mouse and compound diphenoxylate are set up respectively Mouse carries out contrast experiment.By contrast model Mouse Stomach Intestinal motility and defecation situation, the defaecation effect of embodiment 5 is evaluated Really.
From adult male mice 60,6 groups, respectively blank control group, model control group, toxin-expelling and face nourishing are randomly divided into Soft capsule control group, low dosage test group, middle dosage experimental group, high dose test group.
Result of the test：Influence of the ferment probiotics capsule to mouse small intestine propulsion rate is shown in Table 1；To first just time, excrement weight The influence of amount is shown in Table 2.
Influence of the ferment probiotics capsule of table 1 to mouse small intestine propulsion rate
Group Dosage (g/kg) Equivalent to adult's multiple Ink progradation (%)
Negative control 69.15±3.18
Model comparison 38.98±2.74
Toxin-discharging nourishing capsule 0.8 5 70.62±3.37*
Low dosage embodiment 5 0.325 5 78.35±6.58*
Middle dosage embodiment 5 0.65 10 82.93±4.11**
High dose embodiment 5 1.95 30 89.41±4.82**
Note：* it is to be compared p with model control group<0.05；* is to be compared p with model control group<0.01.
Influence of the ferment probiotics capsule of table 2 to mouse defecation
Group Dosage (g/kg) The first just time (s) Stool weight (g)
Negative control 137.21±5.39 0.78.27±0.06
Model comparison 202.75±7.32 0.64.±0.05
Toxin-discharging nourishing capsule 0.8 181.87±6.84 0.68±0.06
Low dosage embodiment 5 0.325 162.83±7.31* 0.67±0.04
Middle dosage embodiment 5 0.65 143.59±7.59** 0.71±0.06
High dose embodiment 5 1.95 130.97±6.27** 0.73±0.04
Note：* it is to be compared p with model control group<0.05；* is to be compared p with model control group<0.01.
Conclusion (of pressure testing)：The ferment probiotics capsule of embodiment 5 can significantly improve the small intestine prepared Chinese ink that small bowel peristalsis suppresses mouse Propulsion rate, shows, can remarkably promote the intestines peristalsis function of mouse；The first just time can also be shortened, increase stool interval, with profit The effect of intestines defaecation.
Model case
Case 1：Female, 31 years old, there is a chronic constipation history for many years, one week defecation 1-2 times, and dry and hard excrement, defecation is not smooth, once in a while There is a bloody stool, daily to take Western medicine anti-inflammatory more, and used plurality of Chinese or Western medicine product are attempted when constipation is felt bad, defecates logical after medication Freely, can also suffer from diarrhoea stomachache sometimes, and medicine main suit occurs again after drug withdrawal：There is chronic constipation medical history for many years, take Chinese medicine or Western medicine, greatly Just it is i.e. unobstructed, recurred after being discontinued, and so on the treatment recurrence several years.First to use after embodiment 1, defaecation in second day is adhered to Take after one week, defecation is gradually smooth, excrement shaping, and without abdominal pain diarrhea malaise symptoms, adhere to using 1 month, cure without multiple Hair.
Case 2：Man, 43 years old, has chronic constipation history for many years, often goes on business, and living and diet work and rest is irregular, and eating is dry peppery Food, once, excrement is hard, is in granular form by 5-7 days rows of natural situation, helps defecation by taking all kinds of medicines relaxed bowel, often After secondary medication 1-3 days just can defecation, be often accompanied by stomachache or the just symptom of frequency, constipation is more serious after drug withdrawal.Embodiment 1 is taken to count After hour, there is the sensation of obvious intestines peristalsis, there is awareness of defecation, normally daily defecation, no sense of discomfort, and excrement can be molded after 2-3 days, Subsequent defecation 5-7 times weekly, after 2 months, not only constipation is cured, and digestive function also take a favorable turn, the symptom of sour regurgitation stomachache Also there is alleviation.
Case 3：Female, 12 years old, constipation 1 year, 3-5 days defecations had awareness of defecation and difficult defecation, often ate banana, the ease constipation such as honey The food of defaecation, when and it is when can take a turn for the better and useless.Early to eat embodiment 4 before the meal, defecation after a few hours adheres to early eating before the meal daily With defecation is smooth every time after 1, one week, first week defecation 5 times adheres to taking that the smooth row of daily getting up early is formed after one month Just custom.
Case 4：Man, 57 years old, chronic constipation many decades, the symptom such as difficult defecation, defecation be not smooth at an early age was early daily One glass of hydromel is played, 1-2 root bananas will be eaten tomorrow, and will still be unable to relief of constipation, weekly defecation 2-3 times.Embodiment 4 is taken, it is sooner or later each After once, second day smooth defecation, the morning and evening, each embodiment 4 adhered to that defecation is smooth after two weeks, defecation 5 times weekly, then An embodiment 4 is taken in getting up early tomorrow, adheres to 2 months, and constipation is cured, no recurrence.
The know-why of the present invention is described above in association with specific embodiment.These descriptions are intended merely to explain the present invention's Principle, and limiting the scope of the invention can not be construed in any way.Based on explanation herein, the technology of this area Personnel, which would not require any inventive effort, can associate other embodiments of the present invention, and these modes are fallen within Within protection scope of the present invention.

Claims (14)

1. a kind of ferment probiotic composition with function of relaxing bowel, it is characterised in that：Include vegetables and fruits plant enzyme powder, Probiotics and dietary fiber；
Vegetables and fruits plant enzyme powder drying and grinding after 540 days viable bacteria fermentations by 60 kinds of natural vegetables and fruits cereal and symbiosis probiotics And obtain；
The probiotics be selected from bifidobacterium longum, animal bifidobacteria, Lactobacillus helveticus, Lactobacillus rhamnosus, lactobacillus acidophilus, One or more in Lactobacillus plantarum, Lactobacillus casei and Bu Ladi yeast；
The dietary fiber be selected from water-soluble dietary fiber inulin, polydextrose, FOS, galactooligosaccharide, resistant dextrin, One or more in konjaku flour；Or Water insoluble dietary fiber common oats fibre, Semen Tritici aestivi fiber, zein fiber, soybean fiber, pea One or more in the luxuriant isapgol husk of beans fiber, circle；Or the combination of water-soluble dietary fiber and Water insoluble dietary fiber；
The mass ratio of the vegetables and fruits plant enzyme powder, probiotics and dietary fiber is (2~60)：(0~2)：(10~80).
2. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：The vegetables and fruits The preparation process of plant enzyme powder is：Selected fresh mature, non-rot fruits and vegetables, cereal are cleaned, cut into slices, osmotic pressure is extracted Fermentation, lactic acid deep-fermentation, acetic acid bacteria storage fermentation, afterripening fermentation, concentration, freeze-drying, grinding and obtain；
Described fruits and vegetables include：Banana, tomato, apple, Kiwi berry, pachyrhizus, pineapple, grape, spinach, cabbage, asparagus, grass The certain kind of berries, lemon, orange, eggplant, wax gourd, pakchoi, guava, balsam pear, corn, lettuce, Sweet Potato Leaf, carambola, three-coloured amaranth, red sugarcane, Sponge gourd, folium artemisiae argyi, wild cabbage, water-rich areas, grape fruit, crowndaisy chrysanthemum, watermelon, plum, asparagus, broccoli, cabbage mustard, passion fruit, cocoa coconut palm Son, cumquat, leaf mustard, water spinach, wheat seedling, muskmelon, black fungus, cauliflower, green pepper, carrot, pumpkin, potato, plum, lotus Mist, cucumber, mushroom, cherry, blue or green river dish, taro, radish；
Described cereal includes：Black soya bean, soya bean, brown rice, mung bean；
The symbiosis probiotics includes saccharomycete, bacillus, lactic acid bacteria, acetic acid bacteria；
540 days described viable bacteria fermentations include four-stage, 180 days extractive fermentation phases, 210 days submerged fermentation phases, storage fermentation 90 days phases, 60 days maturity periods；
The equal single fermentation of described vegetables and fruits plant material is formed after the completion of 540 days according still further to certain ratio chelating；
The moisture requirement of described vegetables and fruits plant enzyme powder is less than 5%.
3. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：It is described prebiotic Bacterium is Lactobacillus helveticus Rosell-0052, Lactobacillus plantarum Rosell-1012, bifidobacterium longum Rosell-0175, animal pair Discrimination bacillus LAFTI B94.
4. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：It is described prebiotic The viable bacteria concentration of bacterium is 1010Cfu/g~5 × 1011cfu/g。
5. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：It is described prebiotic Each bacterial strain percentage is Lactobacillus helveticus Rosell-0052 in bacterium：Lactobacillus plantarum Rosell-1012：Bifidobacterium longum Rosell-0175：Animal bifidobacteria LAFTI B94=(10%~60%)：(8%~32%)：(2%~10%)：(30% ~80%).
6. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：The combination Probiotics viable bacteria concentration in thing is 104Cfu/g~1012Cfu/g, preferably 106Cfu/g~1011Cfu/g, more preferably 108Cfu/g~1010cfu/g。
7. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：The combination Thing controls temperature at 18 DEG C~22 DEG C in preparation process, and humidity is 25%~35%.
8. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：The meals Fiber is inulin, resistant dextrin.
9. there is the ferment probiotic composition of function of relaxing bowel as claimed in claim 1, it is characterised in that：The vegetables and fruits The mass ratio of plant enzyme powder, probiotics and dietary fiber is (25~40)：(0.5~1.5)：(40~70).
10. a kind of application of the ferment probiotic composition with function of relaxing bowel, it is characterised in that：Claim 1~9 times The ferment probiotic composition with function of relaxing bowel described in one is in the guarantor for preparing defaecation, alleviating or treat purgative function Application in strong product.
11. a kind of process preparation of the ferment probiotic composition with function of relaxing bowel, it is characterised in that：Including Juice There is function of relaxing bowel described in powder/slurry, glycitols material, filler, flavouring and any one of claim 1~9 Ferment probiotic composition.
12. there is the process preparation of the ferment probiotic composition of function of relaxing bowel, its feature as claimed in claim 11 It is：The shared mass fraction of the ferment probiotic composition with function of relaxing bowel is 10%~60%.
13. there is the process preparation of the ferment probiotic composition of function of relaxing bowel, its feature as claimed in claim 11 It is：Juice powder/the slurry includes apple juice powder/slurry, grape juice powder/slurry, pineapple juice powder/slurry, lemon juice powder/slurry, strawberry Juice powder/slurry, orange juice powder/slurry, orange juice powder/slurry, grapefruit juice powder/slurry, mango juice powder/slurry, blueberry juice powder/slurry, Cranberry Juice Cocktail Powder/slurry, cherry juice powder/slurry, Lychee juice powder/slurry, bananas juice powder/slurry, coconut milk powder/slurry, Cantaloupe juice powder/slurry, peach juice Powder/slurry, kiwi-fruit juice powder/slurry, pear juice powder/slurry, juice of my pomegranate powder/slurry etc., jujube juice powder/slurry, one kind in oat juice powder/slurry or It is a variety of；
The glycitols material in xylitol, antierythrite, D-sorbite, mannitol, maltitol, lactitol one Plant or a variety of；
One or more of the filler in maltodextrin, starch, microcrystalline cellulose, magnesium stearate；
The flavouring includes the one or more in sweetener, acid and essence；
The sweetener is selected from stevioside, Sucralose, Aspartame, acesulfame potassium, mogroside；Honey, fructose syrup, honeybee One or more in honey, glucose or white granulated sugar；
One or more of the acid in citric acid, malic acid, lactic acid；
The essence is selected from the essence of corresponding fruit powder.
14. there is the process preparation of the ferment probiotic composition of function of relaxing bowel, its feature as claimed in claim 11 It is：The process preparation is solid powder, granule, capsule, oral liquid or tablet.
CN201710199841.3A 2017-03-30 2017-03-30 Ferment probiotic composition with function of relaxing bowel, using and process preparation Pending CN106954847A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710199841.3A CN106954847A (en) 2017-03-30 2017-03-30 Ferment probiotic composition with function of relaxing bowel, using and process preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710199841.3A CN106954847A (en) 2017-03-30 2017-03-30 Ferment probiotic composition with function of relaxing bowel, using and process preparation

Publications (1)

Publication Number Publication Date
CN106954847A true CN106954847A (en) 2017-07-18

Family

ID=59471069

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710199841.3A Pending CN106954847A (en) 2017-03-30 2017-03-30 Ferment probiotic composition with function of relaxing bowel, using and process preparation

Country Status (1)

Country Link
CN (1) CN106954847A (en)

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107348412A (en) * 2017-07-20 2017-11-17 钟祥亿源生物科技有限公司 A kind of coordinating intestines and stomach, relax bowel composition
CN107495049A (en) * 2017-10-17 2017-12-22 广东达明益派生物科技有限公司 Composition for preparing probiotic fermented fruit and vegetable beverage with intestine moistening and bowel relaxing functions, beverage containing composition and preparation method of beverage
CN107568341A (en) * 2017-10-28 2018-01-12 卜球 A kind of formula milk and its production method for being advantageous to human body intestinal canal health
CN107568747A (en) * 2017-10-25 2018-01-12 山东惠民齐发果蔬有限责任公司 A kind of mushroom and witloof diet fiber composition and application thereof
CN107568544A (en) * 2017-11-08 2018-01-12 苏州星圣娜玫瑰园艺有限公司 Rose enzyme drink
CN108056356A (en) * 2018-02-02 2018-05-22 云南瑞宝生物科技股份有限公司 A kind of anthocyanidin solid beverage containing inulin and preparation method thereof
CN108523135A (en) * 2018-03-27 2018-09-14 苏州绿叶日用品有限公司 A kind of composition and its application containing profitable probliotics
CN108576805A (en) * 2018-03-30 2018-09-28 泉州妙吉堂健康管理有限公司 A kind of enzyme composition and preparation method thereof improving constipation
CN108669397A (en) * 2018-05-23 2018-10-19 李春梅 A kind of health-preserving beverage product mix
CN108740665A (en) * 2018-05-24 2018-11-06 国珍健康科技（北京）有限公司 A kind of plant fermentation solid beverage and preparation method thereof
CN108740273A (en) * 2018-04-27 2018-11-06 广东问暖贸易有限公司 A kind of ferment chewing gum and its manufacture craft
CN108968058A (en) * 2018-09-17 2018-12-11 广州乔媛商贸有限公司 It is a kind of improve enteron aisle probiotics enzyme composition and application
CN109010791A (en) * 2018-07-09 2018-12-18 河北东方韵健康管理股份有限公司 A kind of formula and its preparation process of relax bowel and defecation tablet
CN109043273A (en) * 2018-08-28 2018-12-21 吉林标普生物科技有限公司 A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health
CN109043543A (en) * 2018-08-23 2018-12-21 慕恩（广州）生物科技有限公司 Children's probiotic oral composition
CN109125357A (en) * 2018-10-24 2019-01-04 南京益恒寿生命科技有限公司 A kind of probiotics that treating intestinal irritable syndrome-caprophyl liquid complex liquid
CN109247579A (en) * 2018-10-25 2019-01-22 黑龙江惊哲森林农业科技开发有限责任公司 A kind of corn silk hpyerglycemic ferment and preparation method thereof
CN109315664A (en) * 2018-08-27 2019-02-12 杭州维洛斯生物科技有限责任公司 High fine composite fermentation fruits and vegetables solid beverage of a kind of oat taste and preparation method thereof
CN109349644A (en) * 2018-10-30 2019-02-19 广州普维君健药业有限公司 Probiotic composition, health food and its preparation method and application
CN109567177A (en) * 2019-01-26 2019-04-05 陈开兴 A kind of formula and preparation process of the Nutrious fermented oral solution of agaricus bisporus
CN109619358A (en) * 2018-12-12 2019-04-16 中慈保健品科技开发有限公司 A kind of solid drinks and preparation method thereof based on soybean peptide albumen powder
CN109674059A (en) * 2019-03-04 2019-04-26 重庆美均生物制品有限公司 A kind of gut purge ease constipation composition and shaping method
CN109700037A (en) * 2018-12-29 2019-05-03 天津科睿恒生物科技有限公司 Probiotic composition is used in a kind of weight-reducing
CN109730222A (en) * 2019-02-20 2019-05-10 深圳市淳睿贸易有限公司 Ferment complex liquid and its health drink
CN109730184A (en) * 2019-03-12 2019-05-10 厦门元之道生物科技有限公司 A kind of pressed powder prepares the method and pressed candy of ferment pressed candy
CN109832534A (en) * 2018-08-01 2019-06-04 北京姿美堂生物技术有限公司 A kind of functional garden stuff ferment solid beverage and preparation method thereof
CN110024932A (en) * 2019-04-29 2019-07-19 哈尔滨求真生物科技有限公司 A kind of black fungus extract solid drink formula and preparation method thereof for losing weight, improving diarrhea, adjust flora
CN110089737A (en) * 2019-05-08 2019-08-06 深圳市淳睿科技发展有限公司 Comprehensive enzyme composition and preparation method thereof
CN110089751A (en) * 2019-04-02 2019-08-06 大连双迪科技股份有限公司 Intestines arrange health care product
CN110226740A (en) * 2019-01-02 2019-09-13 肖琦 Ferment compound, preparation method and the application in function of intestinal canal adjusting
CN110236065A (en) * 2019-07-29 2019-09-17 广东格物生物科技有限公司 A kind of probiotics solid beverage and preparation method thereof
CN110521786A (en) * 2019-09-26 2019-12-03 天津创源生物技术有限公司 Probiotics fermention yin-nourishing function of relaxing bowel food and its preparation
CN110710659A (en) * 2019-09-16 2020-01-21 湖南科尔生物技术有限公司 Allergy-relieving composition and dietary supplement containing probiotics
CN110721202A (en) * 2019-11-18 2020-01-24 深圳市第三人民医院 Fecal bacteria capsule and preparation method thereof
CN110934244A (en) * 2019-12-23 2020-03-31 天津实发中科百奥工业生物技术有限公司 Preparation method for producing functional series beverages by probiotic fermentation method
CN110973430A (en) * 2019-12-26 2020-04-10 宣城柏维力生物工程有限公司 Preparation method of fermented fruit and vegetable powder
CN111587975A (en) * 2020-04-11 2020-08-28 孙源阔 Solid beverage for improving constipation symptom
CN111607534A (en) * 2020-05-08 2020-09-01 晶叶(银川)生物科技有限公司 Lactobacillus plantarum and application thereof in fruit and vegetable enzyme with constipation relieving effect
CN111869871A (en) * 2020-08-17 2020-11-03 福建省善研高健食品有限责任公司 Probiotics and production process
CN112237287A (en) * 2020-11-26 2021-01-19 河北一然生物科技有限公司 Lactobacillus rhamnosus LR519 capable of relieving constipation and composition thereof
CN112544967A (en) * 2020-11-03 2021-03-26 湖南科尔生物技术有限公司 Fat-reducing prebiotics composite probiotic dietary supplement and preparation method and application thereof
CN112586733A (en) * 2020-12-15 2021-04-02 汉臣氏生物技术(辽宁)集团有限公司 Ferment fermentation stock solution with constipation improving function and preparation method and application thereof
CN112617204A (en) * 2020-12-15 2021-04-09 山东欣瑞文生物科技有限公司 Arabic gum composition with bowel relaxing and constipation relieving effects
CN112617182A (en) * 2020-12-22 2021-04-09 广州能靓生物技术有限公司 Plant enzyme composition for weight management and preparation method thereof
CN112655956A (en) * 2020-12-22 2021-04-16 广州能靓生物技术有限公司 Rutaceae plant enzyme for weight management and preparation method and application thereof
CN112868932A (en) * 2021-02-28 2021-06-01 国药三良(浙江)健康科技有限公司 Pure meat cat food capable of improving digestion characteristic and relieving feces odor and preparation method thereof
CN113462617A (en) * 2021-08-20 2021-10-01 哈尔滨美华生物技术股份有限公司 Whole plant matrix probiotic starter, preparation method and application thereof
CN113519854A (en) * 2021-07-20 2021-10-22 科为博(江苏)生物科技研究院有限公司 Probiotic composition
CN114521638A (en) * 2022-01-25 2022-05-24 安徽妙奇树生物科技股份有限公司 Fruit type enzyme composition collagen jelly and pectin with constipation relieving effect, and preparation method thereof
CN114766676A (en) * 2022-04-24 2022-07-22 安徽东荣堂生物科技有限公司 Tablet for controlling body weight and preparation method thereof
CN115211561A (en) * 2022-07-22 2022-10-21 北京姿美堂生物技术有限公司 Compound fermentation powder and composition with constipation relieving effect and preparation method thereof
CN115211508A (en) * 2021-04-16 2022-10-21 深圳华大海洋科技有限公司 Enzyme beverage and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104397818A (en) * 2014-10-27 2015-03-11 庄小恩 Multifunctional compound health care solid beverage and preparation method thereof
CN104489669A (en) * 2014-12-12 2015-04-08 深圳先进技术研究院 Plant enzyme probiotic powder and preparation method thereof
CN105535580A (en) * 2015-12-21 2016-05-04 上海善力健生物科技有限公司 A biological agent for improving human body intestinal floras and a preparing method thereof
CN105661245A (en) * 2016-01-29 2016-06-15 江苏微康生物科技有限公司 Probiotic type fruit and vegetable enzyme solid drink
CN105687850A (en) * 2016-03-14 2016-06-22 吴利华 Probiotic particles and preparing method thereof
CN106173773A (en) * 2016-07-06 2016-12-07 慧谷生命科技湖北有限公司 A kind of ferment probiotic bacteria solid beverage and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104397818A (en) * 2014-10-27 2015-03-11 庄小恩 Multifunctional compound health care solid beverage and preparation method thereof
CN104489669A (en) * 2014-12-12 2015-04-08 深圳先进技术研究院 Plant enzyme probiotic powder and preparation method thereof
CN105535580A (en) * 2015-12-21 2016-05-04 上海善力健生物科技有限公司 A biological agent for improving human body intestinal floras and a preparing method thereof
CN105661245A (en) * 2016-01-29 2016-06-15 江苏微康生物科技有限公司 Probiotic type fruit and vegetable enzyme solid drink
CN105687850A (en) * 2016-03-14 2016-06-22 吴利华 Probiotic particles and preparing method thereof
CN106173773A (en) * 2016-07-06 2016-12-07 慧谷生命科技湖北有限公司 A kind of ferment probiotic bacteria solid beverage and preparation method thereof

Cited By (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107348412A (en) * 2017-07-20 2017-11-17 钟祥亿源生物科技有限公司 A kind of coordinating intestines and stomach, relax bowel composition
CN107495049A (en) * 2017-10-17 2017-12-22 广东达明益派生物科技有限公司 Composition for preparing probiotic fermented fruit and vegetable beverage with intestine moistening and bowel relaxing functions, beverage containing composition and preparation method of beverage
CN107568747B (en) * 2017-10-25 2020-06-16 山东惠民齐发果蔬有限责任公司 Fungus and chicory dietary fiber composition and application thereof
CN107568747A (en) * 2017-10-25 2018-01-12 山东惠民齐发果蔬有限责任公司 A kind of mushroom and witloof diet fiber composition and application thereof
CN107568341A (en) * 2017-10-28 2018-01-12 卜球 A kind of formula milk and its production method for being advantageous to human body intestinal canal health
CN107568544A (en) * 2017-11-08 2018-01-12 苏州星圣娜玫瑰园艺有限公司 Rose enzyme drink
CN108056356A (en) * 2018-02-02 2018-05-22 云南瑞宝生物科技股份有限公司 A kind of anthocyanidin solid beverage containing inulin and preparation method thereof
CN108523135A (en) * 2018-03-27 2018-09-14 苏州绿叶日用品有限公司 A kind of composition and its application containing profitable probliotics
CN108576805A (en) * 2018-03-30 2018-09-28 泉州妙吉堂健康管理有限公司 A kind of enzyme composition and preparation method thereof improving constipation
CN108740273A (en) * 2018-04-27 2018-11-06 广东问暖贸易有限公司 A kind of ferment chewing gum and its manufacture craft
CN108669397A (en) * 2018-05-23 2018-10-19 李春梅 A kind of health-preserving beverage product mix
CN108740665A (en) * 2018-05-24 2018-11-06 国珍健康科技（北京）有限公司 A kind of plant fermentation solid beverage and preparation method thereof
CN109010791A (en) * 2018-07-09 2018-12-18 河北东方韵健康管理股份有限公司 A kind of formula and its preparation process of relax bowel and defecation tablet
CN109832534A (en) * 2018-08-01 2019-06-04 北京姿美堂生物技术有限公司 A kind of functional garden stuff ferment solid beverage and preparation method thereof
CN109043543A (en) * 2018-08-23 2018-12-21 慕恩（广州）生物科技有限公司 Children's probiotic oral composition
CN109315664A (en) * 2018-08-27 2019-02-12 杭州维洛斯生物科技有限责任公司 High fine composite fermentation fruits and vegetables solid beverage of a kind of oat taste and preparation method thereof
CN109043273A (en) * 2018-08-28 2018-12-21 吉林标普生物科技有限公司 A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health
CN108968058A (en) * 2018-09-17 2018-12-11 广州乔媛商贸有限公司 It is a kind of improve enteron aisle probiotics enzyme composition and application
CN109125357A (en) * 2018-10-24 2019-01-04 南京益恒寿生命科技有限公司 A kind of probiotics that treating intestinal irritable syndrome-caprophyl liquid complex liquid
CN109247579A (en) * 2018-10-25 2019-01-22 黑龙江惊哲森林农业科技开发有限责任公司 A kind of corn silk hpyerglycemic ferment and preparation method thereof
CN109349644A (en) * 2018-10-30 2019-02-19 广州普维君健药业有限公司 Probiotic composition, health food and its preparation method and application
CN109619358A (en) * 2018-12-12 2019-04-16 中慈保健品科技开发有限公司 A kind of solid drinks and preparation method thereof based on soybean peptide albumen powder
CN109700037A (en) * 2018-12-29 2019-05-03 天津科睿恒生物科技有限公司 Probiotic composition is used in a kind of weight-reducing
CN110226740A (en) * 2019-01-02 2019-09-13 肖琦 Ferment compound, preparation method and the application in function of intestinal canal adjusting
CN109567177A (en) * 2019-01-26 2019-04-05 陈开兴 A kind of formula and preparation process of the Nutrious fermented oral solution of agaricus bisporus
CN109730222A (en) * 2019-02-20 2019-05-10 深圳市淳睿贸易有限公司 Ferment complex liquid and its health drink
CN109674059A (en) * 2019-03-04 2019-04-26 重庆美均生物制品有限公司 A kind of gut purge ease constipation composition and shaping method
CN109730184A (en) * 2019-03-12 2019-05-10 厦门元之道生物科技有限公司 A kind of pressed powder prepares the method and pressed candy of ferment pressed candy
CN110089751A (en) * 2019-04-02 2019-08-06 大连双迪科技股份有限公司 Intestines arrange health care product
CN110024932A (en) * 2019-04-29 2019-07-19 哈尔滨求真生物科技有限公司 A kind of black fungus extract solid drink formula and preparation method thereof for losing weight, improving diarrhea, adjust flora
CN110089737A (en) * 2019-05-08 2019-08-06 深圳市淳睿科技发展有限公司 Comprehensive enzyme composition and preparation method thereof
CN110236065A (en) * 2019-07-29 2019-09-17 广东格物生物科技有限公司 A kind of probiotics solid beverage and preparation method thereof
CN110710659A (en) * 2019-09-16 2020-01-21 湖南科尔生物技术有限公司 Allergy-relieving composition and dietary supplement containing probiotics
CN110521786A (en) * 2019-09-26 2019-12-03 天津创源生物技术有限公司 Probiotics fermention yin-nourishing function of relaxing bowel food and its preparation
CN110721202A (en) * 2019-11-18 2020-01-24 深圳市第三人民医院 Fecal bacteria capsule and preparation method thereof
CN110934244A (en) * 2019-12-23 2020-03-31 天津实发中科百奥工业生物技术有限公司 Preparation method for producing functional series beverages by probiotic fermentation method
CN110973430A (en) * 2019-12-26 2020-04-10 宣城柏维力生物工程有限公司 Preparation method of fermented fruit and vegetable powder
CN111587975A (en) * 2020-04-11 2020-08-28 孙源阔 Solid beverage for improving constipation symptom
CN111607534A (en) * 2020-05-08 2020-09-01 晶叶(银川)生物科技有限公司 Lactobacillus plantarum and application thereof in fruit and vegetable enzyme with constipation relieving effect
CN111869871A (en) * 2020-08-17 2020-11-03 福建省善研高健食品有限责任公司 Probiotics and production process
CN112544967A (en) * 2020-11-03 2021-03-26 湖南科尔生物技术有限公司 Fat-reducing prebiotics composite probiotic dietary supplement and preparation method and application thereof
CN112237287A (en) * 2020-11-26 2021-01-19 河北一然生物科技有限公司 Lactobacillus rhamnosus LR519 capable of relieving constipation and composition thereof
CN112237287B (en) * 2020-11-26 2022-11-29 河北一然生物科技股份有限公司 Lactobacillus rhamnosus LR519 capable of relieving constipation and composition thereof
CN112586733A (en) * 2020-12-15 2021-04-02 汉臣氏生物技术(辽宁)集团有限公司 Ferment fermentation stock solution with constipation improving function and preparation method and application thereof
CN112617204A (en) * 2020-12-15 2021-04-09 山东欣瑞文生物科技有限公司 Arabic gum composition with bowel relaxing and constipation relieving effects
CN112617182A (en) * 2020-12-22 2021-04-09 广州能靓生物技术有限公司 Plant enzyme composition for weight management and preparation method thereof
CN112655956A (en) * 2020-12-22 2021-04-16 广州能靓生物技术有限公司 Rutaceae plant enzyme for weight management and preparation method and application thereof
CN112868932A (en) * 2021-02-28 2021-06-01 国药三良(浙江)健康科技有限公司 Pure meat cat food capable of improving digestion characteristic and relieving feces odor and preparation method thereof
CN115211508A (en) * 2021-04-16 2022-10-21 深圳华大海洋科技有限公司 Enzyme beverage and preparation method thereof
CN113519854A (en) * 2021-07-20 2021-10-22 科为博(江苏)生物科技研究院有限公司 Probiotic composition
CN113462617A (en) * 2021-08-20 2021-10-01 哈尔滨美华生物技术股份有限公司 Whole plant matrix probiotic starter, preparation method and application thereof
CN114521638A (en) * 2022-01-25 2022-05-24 安徽妙奇树生物科技股份有限公司 Fruit type enzyme composition collagen jelly and pectin with constipation relieving effect, and preparation method thereof
CN114766676A (en) * 2022-04-24 2022-07-22 安徽东荣堂生物科技有限公司 Tablet for controlling body weight and preparation method thereof
CN115211561A (en) * 2022-07-22 2022-10-21 北京姿美堂生物技术有限公司 Compound fermentation powder and composition with constipation relieving effect and preparation method thereof

Similar Documents

Publication Publication Date Title
CN106954847A (en) Ferment probiotic composition with function of relaxing bowel, using and process preparation
Bae Diets for constipation
CN109123295A (en) A kind of probiotics solid beverage and preparation method thereof
CN106619743A (en) Probiotic solid drink with hypoglycaemic effect and preparation method of probiotic solid drink
KR100937455B1 (en) Bowel movement promotion functional food containing psyllium seed, rice bran fermentation extracts and yeast extracts and manufacturing method thereof
CN106605919A (en) Composition used for removing food retention and relaxing bowels of children, as well as preparation method thereof
CN107455744A (en) A kind of fementative composition ferment and preparation method thereof in vivo
CN108477617A (en) A kind of probiotic powder and preparation method thereof to relax bowel
CN111035014A (en) Probiotic preparation and preparation method thereof
CN111972670A (en) Composition for relaxing bowel, solid beverage and application
CN105249452A (en) Fruit and vegetable enzyme powder with weight reducing function and preparation method thereof
CN105341906A (en) Medical formula food for diabetes
CN104187708A (en) Total-nutrient formulated food for patients with diabetes
CN117487683A (en) Probiotic composition with effects of resisting claustration, protecting stomach, promoting digestion and removing food retention and application thereof
CN111771971A (en) Composition beneficial to regulating intestinal tract, promoting digestion and improving constipation and preparation method thereof
CN106690331A (en) Kelp dietary fiber granules and preparation method thereof
CN106723087A (en) A kind of tablet containing kelp dietary fiber and preparation method thereof
CN109718289A (en) A kind of galactooligosaccharide prebiotic compositions treating or preventing enterogastric diseases
CN108968037A (en) Senile dementia full nutrition formula food
CN106942585A (en) One kind relaxes bowel ground rice and preparation method thereof
CN113974043A (en) Prebiotics solid beverage and preparation method thereof
KR101722481B1 (en) functional cereal containing sweet potato chip, broccoli granule and dietary fiber for constipation improving and manufacturing method thereof
CN102657304A (en) Health-care food with double functions of promoting digestion and relieving physical fatigue
CN102919956B (en) Nutrient solution capable of nursing human digestive system and preparation method thereof
TW202114542A (en) Prebiotic composition for promoting growth ofclostridium butyricumand uses thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170718