CN109043273A - A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health - Google Patents

A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health Download PDF

Info

Publication number
CN109043273A
CN109043273A CN201810985824.7A CN201810985824A CN109043273A CN 109043273 A CN109043273 A CN 109043273A CN 201810985824 A CN201810985824 A CN 201810985824A CN 109043273 A CN109043273 A CN 109043273A
Authority
CN
China
Prior art keywords
powder
parts
lactobacillus
cranberry
probiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810985824.7A
Other languages
Chinese (zh)
Inventor
吴宗翰
邱岩
卢桂娇
李娜
李鹤
郭洪蝀
高文功
李琪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jilin Standard & Poor Biotechnology Co Ltd
Original Assignee
Jilin Standard & Poor Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jilin Standard & Poor Biotechnology Co Ltd filed Critical Jilin Standard & Poor Biotechnology Co Ltd
Priority to CN201810985824.7A priority Critical patent/CN109043273A/en
Publication of CN109043273A publication Critical patent/CN109043273A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385Concentrates of non-alcoholic beverages
    • A23L2/39Dry compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention belongs to technical field of functional food, are related to a kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health.The functionality probiotics solid beverage is grouped as by each group of following parts by weight: 40-50 parts of D-sorbite, 25-35 parts of resistant dextrin, 1-10 parts of oligofructose, 5-15 parts of stachyose, 1-10 parts of Cranberry fruit powder, 1-5 parts of blueberry powder, 1-10 parts of probiotic powder, 0.5-1.5 parts of lactobacillus plantarum powder, 0.1-1 parts of lactobacillus paracasei powder, 0.1-1 parts of Cranberry extract, 0.1-1 parts of Lactobacillus salivarius powder;The probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, and the mass ratio of the two is 4:6.The present invention is prepared using modern production process technology, and supplement lactic acid bacteria, anti-inflammatory and promotion proliferation of probiotics are combined, keep function more significant, safety is higher.It through clinical test, is compared with Baofukang suppository, lactic acid bacteria, functionality probiotics solid beverage significant effect provided by the invention.

Description

A kind of functional probiotics solid beverage and its preparation that maintenance women private shield is healthy Method
Technical field
The invention belongs to technical field of functional food, and in particular to one kind is made of anti-inflammatory component, probiotics and prebiotics Maintenance women private shield health functional probiotics solid beverage and preparation method thereof.
Background technique
With the quickening pace of modern life, people's lives work and rest eating habit is gradually changing, the life of many working womens Object clock is disturbed already, therefore the positive quick step of more and more diseases is come up to women, and constantly seriously threatens comrade women Physical and mental health, such as cervicitis, vaginitis, gynecological tumor, irregular menstruation, abnormal leucorrhea etc..And the wherein disease incidence of vaginitis Highest is the secret anguish that women feels embarrassed to mention, and different times may all cause vaginitis to women for different reasons in life.Vagina Inflammation is not any difficult and complicated cases, but is absolutely a kind of disease for enabling women fully feel torment.It is violent that it not only results in patient's vulva Itch, mucous membrane be red and swollen, leucorrhea increasing and a series of malaise symptoms such as have stench peculiar smell, and leads to pelvic inflammatory disease, introitus honeycomb The Major Risk Factors of inflammation, endometritis, urinary tract infection and other sexually transmitted diseases etc. are organized, and suffer from the pregnant of vaginitis Woman then has the high risk of premature labor, premature rupture of fetal membranes, puerperal infection and infection of newborn.
In recent years, gynecological disease medication market increases quickly, is risen every year with the speedup of 2 digits, the sale of Amino-Cerv It is only second to cold drug, anti-inflammatory drug, pectoral etc., vaginitis medication is even more to rank first.Antibiotic treatment is for vaginitis Traditional treatment means, however more distinct issues, and antibiosis are had become clinically in view of antibiotic resistance and side effect Plain cure rate is not ideal enough, is easy to appear rebound phenomenon.Some researches show that the recurrence rates of antibiotic treatment vaginitis on 70% left side The right side, and extend the recurrence that can not contain vaginitis using the time of antibiotic.
Vaginitis studies carefully its origin cause of formation, is mostly that vaginal flora is unbalance, and the pH of vagina changes the misfortune invited.The vaginal flora of health is logical It is often made of a large amount of Bacillus acidi lactici (gram-positive bacteria), a small amount of gram-Negative bacillus and gram-positive cocci, pH Weakly acidic, pH is maintained between 3.8 to 4.2, is bred by lactobacter growth and is generated secondary metabolite lactic acid to maintain yin The pH value in road.And vagina normal flora frequently can be destroyed using antibiotic, lead to disturbed vaginal flora, function reduction.For this purpose, Treatment about vaginitis proposes new therapy-non-antibiotic therapy, which is to propose the lactic acid bacteria of supplement intravaginal To safeguard vaginal health.Because the side effect of antibiotic is larger, fast-developing imperative, the mesh of non-antibiotic therapy thus Preceding common non-antibiotic class drug is lactobacillus preparation, and application method is in a manner of vagina administration.Lactobacillus preparation effect It is good, without recurrence, but there are certain drawbacks for usage, it has not been convenient to, be not suitable for pregnant woman, medication environmental requirement is higher.And at present Lactobacillus preparation be mostly lactic acid bacteria compounding, ingredient is single.
With the progress of medicine, women increasingly payes attention to private shield health, and existing non-antibiotic class product has list One and disadvantage inconvenient for use, it is not able to satisfy the demand of numerous women, for this purpose, developing a convenient, fast, multicomponent, effect It has been inexorable trend that significant product, which carrys out meet demand,.
Summary of the invention
The object of the present invention is to provide a kind of function of maintenance women private shield health that can be supplemented lactic acid bacteria, have antiinflammation Energy property probiotics solid beverage and preparation method thereof.
To achieve the goals above, technical solution of the present invention is specific as follows:
A kind of functional probiotics solid beverage of maintenance women private shield health, is grouped by each group of following parts by weight At:
40-50 parts of D-sorbite, 25-35 parts of resistant dextrin, 1-10 parts of oligofructose, 5-15 parts of stachyose, Cranberry fruit 1-10 parts of powder, 1-5 parts of blueberry powder, 1-10 parts of probiotic powder, 0.5-1.5 parts of lactobacillus plantarum powder, lactobacillus paracasei powder 0.1-1 parts, 0.1-1 parts of Cranberry extract, 0.1-1 parts of Lactobacillus salivarius powder;
The probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, the Lactobacillus rhamnosus powder and The mass ratio of lactobacillus acidophilus powder is 4:6.
In the above-mentioned technical solutions, the functional probiotics solid beverage of the maintenance women private shield health is by following The each group of parts by weight is grouped as:
45 parts of D-sorbite, 30 parts of resistant dextrin, 5 parts of oligofructose, 10 parts of stachyose, 5 parts of Cranberry fruit powder, blueberry 2.5 parts of fruit powder, 5 parts of probiotic powder, 0.75 part of lactobacillus plantarum powder, 0.5 part of lactobacillus paracasei powder, Cranberry extract 0.5 Part, 0.5 part of Lactobacillus salivarius powder.
In the above-mentioned technical solutions, the functional probiotics solid beverage of the maintenance women private shield health is by following The each group of parts by weight is grouped as:
42 parts of D-sorbite, 27 parts of resistant dextrin, 2 parts of oligofructose, 8 parts of stachyose, 2.5 parts of Cranberry fruit powder, blueberry 2 parts of fruit powder, 3 parts of probiotic powder, 0.7 part of lactobacillus plantarum powder, 0.25 part of lactobacillus paracasei powder, Cranberry extract 0.25 Part, 0.25 part of Lactobacillus salivarius powder.
In the above-mentioned technical solutions, the functional probiotics solid beverage of the maintenance women private shield health is by following The each group of parts by weight is grouped as:
48 parts of D-sorbite, 33 parts of resistant dextrin, 8 parts of oligofructose, 13 parts of stachyose, 8 parts of Cranberry fruit powder, blueberry 4 parts of fruit powder, 8 parts of probiotic powder, 1.2 parts of lactobacillus plantarum powder, 0.8 part of lactobacillus paracasei powder, 0.8 part of Cranberry extract, 0.8 part of Lactobacillus salivarius powder.
A kind of preparation method of the functional probiotics solid beverage of maintenance women private shield health, comprising the following steps:
Step 1 weighs D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry according to above-mentioned parts by weight and mentions Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder are taken, It is spare;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, filling, finished product.
The beneficial effects of the present invention are:
The functional probiotics solid beverage of maintenance women private shield health provided by the invention, is with stachyose, Cranberry Fruit powder, blueberry powder, Cranberry extract, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, saliva cream bar Bacterium powder, lactobacillus paracasei powder are that primary raw material, lactic acid bacteria and Cranberry and blueberry powder interact, and maintenance effects are brighter It is aobvious.Compared with the non-antibiotic class product of market, more convenient, multi-efficiency.The present invention breaks routine, by probiotics and it is anti-inflammatory at Split-phase combines, and pushes non-antibiotic class maintenance women private shield health to a brand-new stage.
The present invention is prepared using modern production process technology, and supplement lactic acid bacteria, anti-inflammatory and promotion proliferation of probiotics are mutually tied It closes, keeps function more significant, safety is higher.
It through clinical test, is compared with Baofukang suppository, lactic acid bacteria, functionality probiotics solid beverage function provided by the invention Effect is significant.
Specific embodiment
Invention thought of the invention: the functional probiotics solid beverage of maintenance women private shield health provided by the invention Maintenance women private is played in terms of supplement lactic acid bacteria, anti-inflammatory, promotion proliferation of probiotics 3 protects healthy effect.
Vagina colony balance directly affects women private shield health.And lactic acid bacteria is the dominant microflora in normal vagina. Vaginal flora is unbalance, easily initiation vaginitis, and vaginitis is prevented not in time will lead to more serious disease.Maintaining vagina bacterium In group's balance, the present invention adds probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder, lactobacillus paracasei powder, Duo Zhongyi Raw bacterium.By field planting effect, the lactic acid bacteria of intravaginal is supplemented, adjusts the pH value of intravaginal, inhibits the growth of harmful bacteria.Together When the present invention in the probiotic powder that adds can not only generate lactic acid, while can also generate hydrogen peroxide (H2O2), hydrogen peroxide tool There is strong oxidisability, can damage cells the basic structure of protein, therefore inhibiting effect can be caused to other bacteriums, moreover it is possible to Ablastins are generated, ablastins inhibition can be secreted by forming probiotic powder lactic acid bacteria by Lactobacillus rhamnosus powder and lactobacillus acidophilus powder Pathogen, advantage are not have drug resistance and toxicity, and be not easy to be destroyed by the trypsin in small intestine, can effectively be inhibited The growth of pathogenic bacteria.The present invention adds a variety of probiotics to supplement vaginal flora comprehensively.
In terms of increasing viable count, the present invention also adds a variety of prebiotics, stachyose and oligofructose.Prebiotics can promote Into breeding of the probiotics in enteron aisle, increase the viable count in enteron aisle, increases the viable count of intravaginal by metabolism.
At anti-inflammatory aspect, the present invention adds pure natural fruit powder-blueberry powder and Cranberry fruit powder with anti-inflammatory efficacy. All contain anthocyanidin in blueberry powder and Cranberry fruit powder.There are many mechanism of action for the effect of its antibacterial anti-inflammatory: anthocyanidin can destroy The cell wall of inflammatory cell and the integrality of cell membrane lead to Microbiological release ingredient intracellular and dead;Inhibit DNA, RNA and The synthesis of protein, leads to bacterial death;Phage structure ingredient is destroyed, changes thalli morphology, ruptures sporoderm, bacterial death. Some researches show that blueberries can inhibit the generation of interleukins IL- tumor necrosis factor TNF-alpha, NF- κ B, lowers an oxidation The mRNA expression of nitrogen synthase is expressed by controlling gene and plays anti-inflammatory effect.The present invention adds natural Anthocyanins and comes Play anti-inflammatory effect.
The present invention acts synergistically probiotic supplemented and prebiotics, promotes the breeding of the probiotics of intravaginal.It adds anti-inflammatory Substance effectively inhibits the growth of harmful bacteria.Supplement lactic acid bacteria, promote probiotics, it is anti-inflammatory combine, multiple efficacies ingredient collaboration Effect, effect are obvious.It is more convenient compared with the non-antibiotic class product of market, functional component more comprehensively, effect it is more significant.This hair It is bright to break routine, push non-antibiotic class maintenance women private shield health to a brand-new stage.
The present invention provides a kind of functional probiotics solid beverage of maintenance women private shield health, is by following parts by weight Each group be grouped as: it is 40-50 parts of D-sorbite, 25-35 parts of resistant dextrin, 1-10 parts of oligofructose, 5-15 parts of stachyose, climing More certain kind of berries fruit powder 1-10 parts, 1-5 parts of blueberry powder, 1-10 parts of probiotic powder, 0.5-1.5 parts of lactobacillus plantarum powder, secondary cheese cream bar 0.1-1 parts of bacterium powder, 0.1-1 parts of Cranberry extract, 0.1-1 parts of Lactobacillus salivarius powder;The probiotic powder is by rhamnose cream bar The mass ratio of bacterium powder and lactobacillus acidophilus powder composition, the Lactobacillus rhamnosus powder and lactobacillus acidophilus powder is 4:6.
It is preferred that the functional probiotics solid beverage of the maintenance women private shield health is by each component of following parts by weight Composition: 45 parts of D-sorbite, 30 parts of resistant dextrin, 5 parts of oligofructose, 10 parts of stachyose, 5 parts of Cranberry fruit powder, blueberry powder 2.5 parts, 5 parts of probiotic powder, 0.75 part of lactobacillus plantarum powder, 0.5 part of lactobacillus paracasei powder, 0.5 part of Cranberry extract, 0.5 part of Lactobacillus salivarius powder.
It is preferred that the functional probiotics solid beverage of the maintenance women private shield health is by each component of following parts by weight Composition: 42 parts of D-sorbite, 27 parts of resistant dextrin, 2 parts of oligofructose, 8 parts of stachyose, 2.5 parts of Cranberry fruit powder, blueberries 2 parts of powder, 3 parts of probiotic powder, 0.7 part of lactobacillus plantarum powder, 0.25 part of lactobacillus paracasei powder, 0.25 part of Cranberry extract, 0.25 part of Lactobacillus salivarius powder.
It is preferred that the functional probiotics solid beverage of the maintenance women private shield health is by each component of following parts by weight Composition: 48 parts of D-sorbite, 33 parts of resistant dextrin, 8 parts of oligofructose, 13 parts of stachyose, 8 parts of Cranberry fruit powder, blueberry powder 4 parts, 8 parts of probiotic powder, 1.2 parts of lactobacillus plantarum powder, 0.8 part of lactobacillus paracasei powder, 0.8 part of Cranberry extract, saliva 0.8 part of lactobacillus powder.
The present invention also provides a kind of preparation method of the functional probiotics solid beverage of maintenance women private shield health, packets Include following steps:
Step 1 weighs D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry according to above-mentioned parts by weight and mentions Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder are taken, It is spare;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, filling, finished product.
Raw material used in following embodiment is bought in following company: D-sorbite is limited by the green strong biotechnology in Shandong Company's supply, resistant dextrin are supplied by hundred garden Long Chuan biotech inc of Shandong, and oligofructose is created by hundred dragon of Shandong The supply of garden biotech inc, stachyose supplied by Chengde Jingtian Food Technology Co., Ltd., Cranberry fruit powder by The supply of Shandong Ge Run Biotechnology Co., Ltd, probiotic powder are supplied by Jingyue Biological Science and Technology Co., Ltd., plant cream bar Bacterium powder is supplied by Jingyue Biological Science and Technology Co., Ltd., and lactobacillus paracasei powder is by Jingyue Biological Science and Technology Co., Ltd. Supply, Lactobacillus salivarius powder are supplied by Jingyue Biological Science and Technology Co., Ltd., and blueberry powder is had by Shandong Ge Run biotechnology The supply of limit company, Cranberry extract are supplied by Shandong Ge Run Biotechnology Co., Ltd.
Embodiment 1
The present invention provides a kind of functional probiotics solid beverage of maintenance women private shield health, is by following weight Group is grouped as:
D-sorbite 45g, resistant dextrin 30g, oligofructose 5g, stachyose 10g, Cranberry fruit powder 5g, blueberry powder 2.5g, probiotic powder 5g, lactobacillus plantarum powder 0.75g, lactobacillus paracasei powder 0.5g, Cranberry extract 0.5g, saliva cream Bacillus powder 0.5g.Wherein the probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, the mass ratio of the two For 4:6.
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Embodiment 2
The present invention provides a kind of functional probiotics solid beverage of maintenance women private shield health, is by following weight Group is grouped as:
D-sorbite 42g, resistant dextrin 27g, oligofructose 2g, stachyose 8g, Cranberry fruit powder 2.5g, blueberry powder 2g, probiotic powder 3g, lactobacillus plantarum powder 0.7g, lactobacillus paracasei powder 0.25g, Cranberry extract 0.25g, saliva cream Bacillus powder 0.25g.Wherein the probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, the quality of the two Than for 4:6.
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Embodiment 3
The present invention provides a kind of functional probiotics solid beverage of maintenance women private shield health, is by following weight Group is grouped as:
D-sorbite 48g, resistant dextrin 33g, oligofructose 8g, stachyose 13g, Cranberry fruit powder 8g, blueberry powder 4g, probiotic powder 8g, lactobacillus plantarum powder 1.2g, lactobacillus paracasei powder 0.8g, Cranberry extract 0.8g, saliva cream bar Bacterium powder 0.8g.Wherein the probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, and the mass ratio of the two is 4:6。
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Embodiment 4
The present invention provides a kind of functional probiotics solid beverage of maintenance women private shield health, is by following weight Group is grouped as:
D-sorbite 40g, resistant dextrin 25g, oligofructose 1g, stachyose 5g, Cranberry fruit powder 1g, blueberry powder 1g, 1g parts of probiotic powder, 0.5g parts of lactobacillus plantarum powder, lactobacillus paracasei powder 0.1g, Cranberry extract 0.1g, saliva cream bar Bacterium powder 0.1g;Wherein the probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, and the mass ratio of the two is 4:6。
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Embodiment 5
The present invention provides a kind of functional probiotics solid beverage of maintenance women private shield health, is by following weight Group is grouped as:
D-sorbite 50g, resistant dextrin 35g, oligofructose 10g, stachyose 15g, Cranberry fruit powder 10g, blueberry powder 5g, probiotic powder 10g, lactobacillus plantarum powder 1.5g, lactobacillus paracasei powder 1g, Cranberry extract 1g, Lactobacillus salivarius powder 1g;Wherein the probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, and the mass ratio of the two is 4:6.
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Each component content balance embodiment 6
A kind of functional probiotics solid beverage of maintenance women private shield health, is grouped as by the group of following weight:
D-sorbite 35g, resistant dextrin 20g, oligofructose 0.5g, stachyose 2g, Cranberry fruit powder 0.5g, blueberries Powder 0.5g, probiotic powder 0.5g, 0.2g parts of lactobacillus plantarum powder, lactobacillus paracasei powder 0.05g, Cranberry extract 0.05g, Lactobacillus salivarius powder 0.05g.Wherein the probiotic powder is by Lactobacillus rhamnosus powder and lactobacillus acidophilus powder group At the mass ratio of the two is 4:6.
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Each component content balance embodiment 7
A kind of functional probiotics solid beverage of maintenance women private shield health, is grouped as by the group of following weight:
D-sorbite 55g, resistant dextrin 40g, oligofructose 15g, stachyose 20g, Cranberry fruit powder 15g, blueberry powder 10g, probiotic powder 15g, lactobacillus plantarum powder 2g, lactobacillus paracasei powder 1.5g, Cranberry extract 1.5g, saliva cream bar Bacterium powder 1.5g.Wherein the probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, and the mass ratio of the two is 4:6。
Step 1 is weighed D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extraction by above-mentioned weight Object, oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is standby With;
Step 2, by the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei Powder is sufficiently mixed, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, And oligofructose, it is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, finished product filling, that every bag of 2g is made.
Clinical trial design:
Tested crowd: the voluntary tested married femle with vaginitis, the age in 20-45 one full year of life, without other aspect diseases Disease does not take drug related with tested function in a short time, to this test product not allergy sufferers.
Test grouping: 600 subjects are randomly divided into 10 groups according to intestinal condition and age condition, every group of 60 people, 7 groups of middle test group, 1 group of control group, 1 group of antibiotic group, 1 group of lactic acid bacteria group.
Eating method: test group and control group, are that 2 times a day, one bag each time, are continuously taken 30 days.Antibiotic group and Lactic acid bacteria group is 1 time every night, 1 tablet each time, uses 7-8 days.
Each group takes product:
1, control group: D-sorbite 100g is made 2g/ bags.
2, antibiotic group: Baofukang suppository is produced by Hainan Bikai Pharmaceutical Co., Ltd.
3, lactic acid bacteria group: lactobacillus vaginal capsule is produced by Xi'an Zhenghao Biological Pharmaceutical Co., Ltd..
4, test group 1-7 group: the finished product of 1-7 of embodiment of the present invention preparation is taken respectively.
Clinical test results, see Table 1 for details.
Influence of the table 1 to subject's vaginal conditions
As known from Table 1, it is compared with antibiotic group, lactic acid bacteria group, functionality probiotics solid beverage pair provided by the invention The maintenance effects of vagina health are significant.And it tests 1-3 group to get well than testing 4 and comparing maintenance effects also with 5 groups, try It is best to test 1 group maintenance effect.1-5 is relatively tested in test 6 with 7 groups of maintenance effects, and to compare maintenance effects unobvious.Illustrate the present invention The dosage of each component must can be only achieved present invention maintenance vagina health within the scope of the parts by weight that limit of the present invention Effect.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments. For those of ordinary skill in the art, other various forms of changes can also be made on the basis of the above description Change or changes.There is no necessity and possibility to exhaust all the enbodiments.And obvious change extended from this Change or changes still within the protection scope of the invention.

Claims (5)

1. a kind of functional probiotics solid beverage of maintenance women private shield health, which is characterized in that be by following parts by weight Each group is grouped as:
40-50 parts of D-sorbite, 25-35 parts of resistant dextrin, 1-10 parts of oligofructose, 5-15 parts of stachyose, Cranberry fruit powder 1- 10 parts, 1-5 parts of blueberry powder, 1-10 parts of probiotic powder, 0.5-1.5 parts of lactobacillus plantarum powder, lactobacillus paracasei powder 0.1-1 Part, 0.1-1 parts of Cranberry extract, 0.1-1 parts of Lactobacillus salivarius powder;
The probiotic powder is made of Lactobacillus rhamnosus powder and lactobacillus acidophilus powder, the Lactobacillus rhamnosus powder and acidophilus cream The mass ratio of bacillus powder is 4:6.
2. the functional probiotics solid beverage of maintenance women private shield health according to claim 1, which is characterized in that be It is grouped as by each group of following parts by weight:
45 parts of D-sorbite, 30 parts of resistant dextrin, 5 parts of oligofructose, 10 parts of stachyose, 5 parts of Cranberry fruit powder, blueberry powder 2.5 parts, 5 parts of probiotic powder, 0.75 part of lactobacillus plantarum powder, 0.5 part of lactobacillus paracasei powder, 0.5 part of Cranberry extract, saliva 0.5 part of liquid lactobacillus powder.
3. the functional probiotics solid beverage of maintenance women private shield health according to claim 1, which is characterized in that be It is grouped as by each group of following parts by weight:
42 parts of D-sorbite, 27 parts of resistant dextrin, 2 parts of oligofructose, 8 parts of stachyose, 2.5 parts of Cranberry fruit powder, blueberry powder 2 Part, 3 parts of probiotic powder, 0.7 part of lactobacillus plantarum powder, 0.25 part of lactobacillus paracasei powder, 0.25 part of Cranberry extract, saliva 0.25 part of lactobacillus powder.
4. the functional probiotics solid beverage of maintenance women private shield health according to claim 1, which is characterized in that be It is grouped as by each group of following parts by weight:
48 parts of D-sorbite, 33 parts of resistant dextrin, 8 parts of oligofructose, 13 parts of stachyose, 8 parts of Cranberry fruit powder, blueberry powder 4 Part, 8 parts of probiotic powder, 1.2 parts of lactobacillus plantarum powder, 0.8 part of lactobacillus paracasei powder, 0.8 part of Cranberry extract, saliva cream 0.8 part of bacillus powder.
5. a kind of system of the functional probiotics solid beverage of the shield health of maintenance women private described in claim 1-4 any one Preparation Method, which comprises the following steps:
Step 1, weighed according to above-mentioned parts by weight D-sorbite, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract, Oligofructose, resistant dextrin, probiotic powder, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder, it is spare;
Step 2 fills the weighed probiotic powder of step 1, lactobacillus plantarum powder, Lactobacillus salivarius powder and lactobacillus paracasei powder Divide mixing, then the weighed resistant dextrin equal increments of step 1 are added in aforementioned Mixed Microbes powder, obtains mixed powder 1;
Step 3, by the weighed D-sorbite of step 1, stachyose, Cranberry fruit powder, blueberry powder, Cranberry extract and low Fructooligosaccharides is sufficiently mixed with mixed powder 1, obtains total mixed powder, total mix, filling, finished product.
CN201810985824.7A 2018-08-28 2018-08-28 A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health Pending CN109043273A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810985824.7A CN109043273A (en) 2018-08-28 2018-08-28 A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810985824.7A CN109043273A (en) 2018-08-28 2018-08-28 A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health

Publications (1)

Publication Number Publication Date
CN109043273A true CN109043273A (en) 2018-12-21

Family

ID=64757406

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810985824.7A Pending CN109043273A (en) 2018-08-28 2018-08-28 A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health

Country Status (1)

Country Link
CN (1) CN109043273A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109588724A (en) * 2019-01-28 2019-04-09 江西美好时光生物科技有限公司 A kind of probiotic powder and preparation method thereof improving stomach trouble
CN109619596A (en) * 2019-01-28 2019-04-16 江西美好时光生物科技有限公司 A kind of probiotic powder of recuperating astriction and preparation method thereof
CN110140773A (en) * 2019-06-27 2019-08-20 格乐瑞(无锡)营养科技有限公司 A kind of probiotics solid beverage, preparation method and applications
CN110693007A (en) * 2019-10-25 2020-01-17 李玉保 Probiotics compound nutrient for inhibiting gynecological inflammation and promoting cell metabolism and preparation method thereof
CN110772629A (en) * 2019-10-25 2020-02-11 国众兴合生物医药科技有限公司 Probiotics compound botanical drug for treating gynecological inflammation and improving immunity and preparation method thereof
CN111096452A (en) * 2020-02-21 2020-05-05 江西林丰药业有限公司 Plant probiotic powder or liquid for inhibiting labial melanin and removing peculiar smell and preparation method thereof
CN111150059A (en) * 2020-01-19 2020-05-15 西倍健生物科技(深圳)有限公司 Special probiotic bacterium composition for women and application thereof
CN115137758A (en) * 2022-06-08 2022-10-04 诺佰克(武汉)生物科技有限公司 Preparation and application of probiotics beneficial to female genital tract health

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104432092A (en) * 2014-11-30 2015-03-25 邵素英 Probiotic tablet and preparation method thereof
CN105661245A (en) * 2016-01-29 2016-06-15 江苏微康生物科技有限公司 Probiotic type fruit and vegetable enzyme solid drink
CN106954847A (en) * 2017-03-30 2017-07-18 广州能靓生物技术有限公司 Ferment probiotic composition with function of relaxing bowel, using and process preparation
CN108402458A (en) * 2018-04-26 2018-08-17 华纳时代健康科技(武汉)股份有限公司 A kind of feedstock composition of health products and its application and combined drinks and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104432092A (en) * 2014-11-30 2015-03-25 邵素英 Probiotic tablet and preparation method thereof
CN105661245A (en) * 2016-01-29 2016-06-15 江苏微康生物科技有限公司 Probiotic type fruit and vegetable enzyme solid drink
CN106954847A (en) * 2017-03-30 2017-07-18 广州能靓生物技术有限公司 Ferment probiotic composition with function of relaxing bowel, using and process preparation
CN108402458A (en) * 2018-04-26 2018-08-17 华纳时代健康科技(武汉)股份有限公司 A kind of feedstock composition of health products and its application and combined drinks and preparation method thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109588724A (en) * 2019-01-28 2019-04-09 江西美好时光生物科技有限公司 A kind of probiotic powder and preparation method thereof improving stomach trouble
CN109619596A (en) * 2019-01-28 2019-04-16 江西美好时光生物科技有限公司 A kind of probiotic powder of recuperating astriction and preparation method thereof
CN110140773A (en) * 2019-06-27 2019-08-20 格乐瑞(无锡)营养科技有限公司 A kind of probiotics solid beverage, preparation method and applications
CN110693007A (en) * 2019-10-25 2020-01-17 李玉保 Probiotics compound nutrient for inhibiting gynecological inflammation and promoting cell metabolism and preparation method thereof
CN110772629A (en) * 2019-10-25 2020-02-11 国众兴合生物医药科技有限公司 Probiotics compound botanical drug for treating gynecological inflammation and improving immunity and preparation method thereof
CN111150059A (en) * 2020-01-19 2020-05-15 西倍健生物科技(深圳)有限公司 Special probiotic bacterium composition for women and application thereof
CN111096452A (en) * 2020-02-21 2020-05-05 江西林丰药业有限公司 Plant probiotic powder or liquid for inhibiting labial melanin and removing peculiar smell and preparation method thereof
CN115137758A (en) * 2022-06-08 2022-10-04 诺佰克(武汉)生物科技有限公司 Preparation and application of probiotics beneficial to female genital tract health
CN115137758B (en) * 2022-06-08 2024-01-19 诺佰克(武汉)生物科技有限公司 Preparation and application of probiotics beneficial to female genital tract health

Similar Documents

Publication Publication Date Title
CN109043273A (en) A kind of functional probiotics solid beverage and preparation method thereof of maintenance women private shield health
EP2996701B1 (en) Composition comprising lactic acid bacteria for use in the preventive and/or curative treatment of bacterial vaginosis
EP2667849B1 (en) Effervescent composition in solid form for use in vaginal applications for the treatment of vaginal infections
AU2016353091B2 (en) Probiotic delivery systems
AU2017211244B2 (en) Faecalibacterium prausnitzii strain CNCM 1-4573 for the treatment and prevention of gastrointestinal inflammation
EP3035943B1 (en) Strain of lactobacillus pentosus as probiotic
CN101797304B (en) Gel for adjusting microecology in vaginas of women
CN111972670A (en) Composition for relaxing bowel, solid beverage and application
CN109394794A (en) The composite probiotics preparations and preparation method of prophylactic treatment gynecological disease and application
CN110201004A (en) A kind of woman's probiotic composition, preparation method, its application and feminine care products
Nader‐Macías et al. Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract
CN106721834A (en) A kind of solid beverage for improving women's health problem
CN102524640A (en) Gut purging powder capable of shaping intestine-like model
CN114869917B (en) Application of lactobacillus plantarum N13 in preparation of medicine for preventing and treating vaginitis or inhibiting pathogenic bacteria
ES2873075T3 (en) Lactobacillus plantarum probiotic strains for urinary tract infections
WO2019245912A1 (en) Improving health of the microbiome in a human gastrointestinal system and multi-chamber probiotic delivery products therefor
WO2021103776A1 (en) Compound preparation having auxiliary effect of preventing and treating psychological depression in children and adolescents
CN108338993A (en) A kind of symphysis unit composition of conditioning female reproductive health and its preparation and application
CN107279234A (en) The biscuit of healthy intestinal health
CN111821321A (en) Probiotics composition for nursing female reproductive system
TW202207958A (en) Compositions and combinations intended for subjects suffering from endometriosis
TW201942352A (en) Lactic acid bacteria composition capable of preventing and treating bacterial vaginitis by inhibiting the growth of pathogenic bacteria and regulating the expression of immunoregulatory factors
CN101530405B (en) Citric acid and compound citric acid application in pharmacy
CN111296842B (en) Probiotic composition with anti-allergy effect
Smejkal et al. Probiotics and prebiotics in female health

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20181221