CN110024932A - A kind of black fungus extract solid drink formula and preparation method thereof for losing weight, improving diarrhea, adjust flora - Google Patents

A kind of black fungus extract solid drink formula and preparation method thereof for losing weight, improving diarrhea, adjust flora Download PDF

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Publication number
CN110024932A
CN110024932A CN201910354913.6A CN201910354913A CN110024932A CN 110024932 A CN110024932 A CN 110024932A CN 201910354913 A CN201910354913 A CN 201910354913A CN 110024932 A CN110024932 A CN 110024932A
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China
Prior art keywords
solid beverage
parts
beverage formula
preparation
black fungus
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CN201910354913.6A
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Inventor
孔祥辉
凃婧
吕裔刚
高洋
聂武
任立东
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Harbin Qiuzhen Biotechnology Co Ltd
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Harbin Qiuzhen Biotechnology Co Ltd
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Priority to CN201910354913.6A priority Critical patent/CN110024932A/en
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A23L2/39—Dry compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A23L2/39—Dry compositions
    • A23L2/395—Dry compositions in a particular shape or form
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733—Fructosans, e.g. inulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/113—Acidophilus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/169—Plantarum
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/51—Bifidobacterium
    • A23V2400/531—Lactis

Abstract

The present invention provides a kind of solid beverage formula, it further includes buckwheat oligopeptide that formula, which contains black fungus extract, oligofructose, inulin, probiotic powder,.It additionally provides and a kind of preparation method for losing weight, improve diarrhea, adjusting flora solid beverage formula is provided.A kind of solid beverage formula is further provided in preparation weight-reducing or improves diarrhea or adjusts the application in flora food or Special food or drug.

Description

A kind of black fungus extract solid beverage for losing weight, improving diarrhea, adjust flora Formula and preparation method thereof
Technical field
The present invention relates to food, Special food, medicine field, in particular to one kind for lose weight, improve diarrhea, Adjust the black fungus extract solid drink formula and preparation method thereof of flora.
Background technique
Adult gastrointestinal tract mucous surface area is body and the maximum device that external environment interacts up to 300 square metres Official.A large amount of fungal component is inhabited in human gastrointestinal tract, type is more than 1000 kinds, and total weight is close to 2 kilograms；Total number of bacteria reaches 100000000000000, about the 10 of human body cell summation times；Its gene encoded is about 150 times of human genome, therefore it is regarded It is another " hiding organ " for human body, carry human body " the second gene ".
According to the relationship with host, enteric microorganism can be divided into probiotics, conditioned pathogen and pathogenic bacteria.Probiotics is Referring to improves host's microecological balance and plays beneficial effect, reach improve that host health is horizontal and the active bacteria formulation of health status and Its metabolite.Beneficial bacteria of intestinal tract is mainly reflected in the metabolism for participating in nutriment to human body effect, biological barrier effect, is immunized Effect etc..
Under normal circumstances, the intestinal microecology of Healthy People maintains a relatively stable state, but human enteric bacteria group structure is simultaneously It is not constant between, but is in dynamic equilibrium.Age, diet, gender, environment, health status and long-term a large amount of uses are wide Spectrum antibiotic can impact intestinal microflora, so that human gastrointestinal tract be made to be among risk.Studies have shown that fertile Fat, acute and chronic diarrhea, constipation, indigestion, chronic hepatic diseases, diabetes, atherosclerosis and mental disease etc. all with Intestinal flora has substantial connection, how by nutritional intervention adjusting intestinal microflora, micro-ecological environment, to reduce this kind of disease The disease incidence of disease, oneself becomes the important topic studied in the art.
Although there is the product of probiotics, prebiotics or synbiotic now, it is most of be by supplement merely it is single or Several floras or simple prebiotic-supplemented or the simple combination of probiotics and prebiotics, without type needed for growth of probiotics The supplement of complete system trophism object, cause prebiotics and probiotics to be absorbed and utilized degree lower, by improving supplement merely Prebiotics and probiotics type and quantity can not build the long-term health condition of enteron aisle, palliative, ask gastrointestinal health Topic cannot be well solved.
Summary of the invention
The first aspect of the present invention is designed to provide a kind of solid beverage formula.
A kind of preparation method for being designed to provide solid beverage of the second aspect of the present invention.
The third aspect of the present invention be designed to provide it is a kind of weight-reducing, improve diarrhea, adjustment flora matched with solid beverage Side.
The fourth aspect of the present invention be designed to provide it is a kind of weight-reducing, improve diarrhea, adjustment flora matched with solid beverage The preparation method of side.
The fifth aspect of the present invention has been designed to provide a kind of solid beverage formula in preparation weight-reducing or improves diarrhea Or the application in adjustment flora food or Special food or drug.
In order to realize above-mentioned purpose of the invention, the following technical scheme is adopted:
A kind of solid beverage formula contains black fungus extract, oligofructose, inulin, probiotic powder.
Further, which further includes buckwheat oligopeptide.
Each material of recipe quantity is weighed, routinely preparation method makes solid beverage.
Powder, tablet, capsule, granule or oral solution can be made in solid beverage formula.
The preparation method of solid beverage formula is produced using dry process, comprising the following steps: crush, sieving, be pre-mixed, Total mix, packing, packaging.
Above-mentioned solid beverage formula is in preparation weight-reducing or improves in diarrhea or adjustment flora food or Special food or drug Application.
Compared with prior art, present disclosure the utility model has the advantages that
Inulin, oligofructose, these sweeteners substitute sucrose for general population, especially diabetic, have weight Want meaning.For fat type 2 diabetic patient, loss of weight can improve insulin resistance, to help to control blood glucose.Body The every reduction 1kg of weight, blood pressure decline about 1mmHg, and the triglycerides in blood lipid declines about 2mmol/L, blood glucose decline about 10%.
Volume expansion after the water suction of black fungus extract etc. contained by product becomes the sticking dietary fiber of tool, can subtract Slow food passing through from stomach to small intestine delays digestion and absorption nutriment so that fatty acid is existed due to reducing the absorption of monosaccharide Synthesis decline in vivo, to achieve the effect that weight-reducing.A kind of satiety is generated after product is edible, plays control to a certain extent The effect of diet.Raw material in product has the effect of improving diarrhea, makes partially not being digested the nutriment of absorption with excrement Ease constipation weight-reducing is played the role of in discharge.
Product of the present invention weight reducing moulding, generates satiety, the fine figure of shape healthy；Improve diarrhea, improves constipation, clearly Manage the toxin of enteron aisle and the accumulation of body median year.
The solid beverage that present disclosure provides, black fungus extract, oligofructose, chrysanthemum than independent identical weight number Powder, probiotic powder, buckwheat oligopeptide, better effect.Multicomponent plays synergistic weight-reducing jointly, improves diarrhea and immune tune Section effect.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is The conventional products that can be obtained by commercially available purchase, lactobacillus plantarum, lactobacillus acidophilus, the bacterium that bifidobacterium lactis is market purchasing Powder raw material (10~300,000,000,000 cfu/g).
Present embodiment provides a kind of solid beverage formula, contains black fungus extract, oligofructose, inulin, probiotics Powder.
Further, which further includes buckwheat oligopeptide.
Further, the solid beverage formula contains 200~500 parts of black fungus extract, low according to parts by weight 60~200 parts of Fructooligosaccharides, 30~80 parts of inulin, 10~90 parts of probiotic powder, 30~80 parts of buckwheat oligopeptide.
Preferably, the solid beverage formula contains 300 parts of black fungus extract, oligofructose 100 according to parts by weight Part, 50 parts of inulin, 50 parts of probiotic powder, 50 parts of buckwheat oligopeptide.
The preparation method of solid beverage, routinely preparation method makes.Can weigh by formula rate can be by matching Square ratio weighs the materials such as a certain amount of black fungus extract and is uniformly mixed, and ethanol solution makees wetting agent, continues stirring 15 minutes, So that material is reached the state of " that holds is agglomerating, and touching dissipates ", is pelletized with 16 mesh screens, (temperature is kept for 60 DEG C, and the time is for drying 1.5~2 hours), after drying with 16 mesh screen whole grains to get.
The preparation method of the solid beverage formula, comprising the following steps:
Raw material is weighed by weight；80 mesh crush, 50 mesh sieves, and premixing is mixed by equal increments method, take a small amount of The big component of the amount of component and equivalent, while being placed in mixing machinery and being uniformly mixed, the amount for adding same mixture equivalent are big Component is uniformly mixed, and so a times amount is increased up until adding the big component of whole amount.Incorporation time 25~35 minutes, revolving speed was 8~10 revs/min, total mix is mixed using three-dimensional motion mixer, and incorporation time 25~35 minutes, solid beverage formula is made.
Present embodiment also provides a kind of preparation, which includes above-mentioned solid beverage formula and food, special food Oral preparation can be made in product or pharmaceutically acceptable carrier or auxiliary material.
Said preparation can be powder, tablet, capsule, granule or oral solution.
Herein, term " food, Special food or pharmaceutically acceptable " refers to the chemical combination when compound is to human administration Object is physiologically acceptable, and the allergic reactions such as gastrointestinal disturbance, dizziness or anaphylactoid similar to these will not occur Systemic anaphylaxis.
In the present invention, " food, Special food or pharmaceutically acceptable carrier or auxiliary material " includes but is not limited to: bonding Agent (such as microcrystalline cellulose, alginates, gelatin and polyvinylpyrrolidone), filler (such as starch, sucrose, glucose and anhydrous Lactic acid), disintegrating agent (such as cross-linked pvp, crosslinked carboxymethyl fecula sodium, croscarmellose sodium and low substituted hydroxy-propyl fiber Element), lubricant (magnesium stearate, aluminum stearate, talcum, polyethylene glycol, sodium benzoate), wetting agent (such as glycerol), surface-active Agent (such as hexadecanol) and sorbefacient, corrigent, sweetener, diluent, coating agent.
Present embodiment also provides a kind of above-mentioned solid beverage formula in preparing diet food or Special food or drug Application.
Feature of the invention is described in further detail with reference to embodiments:
Embodiment 1
The present embodiment provides a kind of solid beverage formulas comprising:
Weigh 300 grams of black fungus extract, 300 grams of oligofructose, 50 grams of inulin, probiotic powder (lactobacillus acidophilus) 50 Gram, 120 mesh crush respectively, 100 mesh sieves, mix 30 minutes, and ethanol solution makees wetting agent, continue stirring 15 minutes, make object Material reaches the state of " that holds is agglomerating, and touching dissipates ", is pelletized with 16 mesh screens, and (temperature is kept for 60 DEG C, and the time is 1.5 small for drying When), after drying with 16 mesh screen whole grains to get.
Embodiment 2
The present embodiment provides a kind of solid beverage formulas comprising:
200 grams of black fungus extract, 200 grams of oligofructose, 30 grams of inulin, probiotic powder 90 grams of (lactobacillus plantarum), buckwheats 30 grams of wheat oligopeptide, 120 mesh crush respectively, 100 mesh sieves, mix 30 minutes, ethanol solution makees wetting agent, continues stirring 15 Minute makes material reach the state of " that holds is agglomerating, and touching dissipates ", is pelletized with 16 mesh screens, drying (60 DEG C of temperature holding, when Between be 2 hours), after drying with 16 mesh screen whole grains to get.
Embodiment 3
The present embodiment provides a kind of solid beverage formulas comprising:
500 parts of black fungus extract, 60 parts of oligofructose, 80 parts of inulin, probiotic powder (lactobacillus plantarum: newborn bifid bar Bacterium=3:5) 30 parts, 80 parts of buckwheat oligopeptide, 120 mesh crush respectively, 100 mesh sieves, mix 30 minutes, ethanol solution is made wet Moisten agent, continue stirring 15 minutes, so that material is reached the state of " that holds is agglomerating, and touching dissipates ", pelletized with 16 mesh screens, drying (temperature keep 60 DEG C, the time be 1.5 hours), after drying with 16 mesh screen whole grains to get.
Embodiment 4
(lactobacillus acidophilus: cream is double for 300 grams of black fungus extract, 80 grams of oligofructose, 50 grams of inulin, 30 grams of probiotic powder Discrimination bacillus=2:5), 30 grams of buckwheat oligopeptide, respectively 120 mesh crush, 100 mesh sieves, mix 30 minutes, ethanol solution is made wet Moisten agent, continue stirring 15 minutes, so that material is reached the state of " that holds is agglomerating, and touching dissipates ", pelletized with 16 mesh screens, drying (temperature keep 60 DEG C, the time be 2 hours), after drying with 16 mesh screen whole grains to get.
Embodiment 5
300 grams of black fungus extract, 100 grams of oligofructose, 50 grams of inulin, probiotic powder (lactobacillus plantarum: acidophilus cream bar Bacterium: bifidobacterium lactis=3:2:5) 10 grams, 50 grams of buckwheat oligopeptide, 120 mesh crush respectively, and 100 mesh sieves are placed in mixing machine Incorporation time 30 minutes, revolving speed was 10 revs/min, and total mix is mixed using three-dimensional motion mixer, incorporation time 30 minutes, was made solid Body drink formula.
Embodiment 6
300 grams of black fungus extract, 100 grams of oligofructose, 50 grams of inulin, probiotic powder (lactobacillus plantarum: acidophilus cream bar Bacterium 3:2) 50 grams, 50 grams of buckwheat oligopeptide, 120 mesh crush respectively, and 100 mesh sieves are placed in mixing machine incorporation time 30 minutes, Revolving speed is 9 revs/min, and total mix is mixed using three-dimensional motion mixer, and incorporation time 30 minutes, solid beverage formula is made.
Embodiment 7
The present embodiment provides a kind of tablet, the preparation method of the tablet includes:
Appropriate amount of starch, dextrin is added in 6 solid beverage formula of above-described embodiment, is uniformly mixed, and particle is made, and tabletting is wrapped thin Film clothing is to get tablet.
Embodiment 8
The present embodiment provides a kind of capsule, the preparation method of the capsule includes:
Appropriate amount of starch, dextrin is added in 6 solid beverage formula of above-described embodiment, mixes, and particle is made, and is packed into hard capsule, i.e., Obtain capsule.
Embodiment 9
The present embodiment provides a kind of granule, the preparation method of the granule includes:
Appropriate amount of starch, dextrin is added in 6 solid beverage formula of above-described embodiment, mixes, wet granulation, whole grain after drying, packet Dress is to get granule.
Experimental example 1
Select rat 70,180-220 grams of weight.It is randomly divided into 7 groups, every group 10, respectively Normal group, specific Embodiment 1-6 group.
7 groups of rats change feeding high lipid food, and (formula is 78.8% basal feed, 1% cholesterol, 10% yolk powder, 10% Lard, 0.2% cholate), it feeds 7 days.
After 7 days, Normal group feeds normal diet；Specific embodiment 1-6 group feeds above-mentioned specific embodiment 1-6 group Formula is fed 30 days.
After 30 days, fasting 12h after last feeding, after weighing, rat plucks eyeball and takes blood, serum is separated, with kit side Method surveys TG, TC.
Table 1 to rat weight influence (N=10)
Group Weight
Normal group 208.6±19.9
Example 1 group 203.8±20.2
2 groups of embodiment 205.6±19.1
3 groups of embodiment 201.8±18.5
4 groups of embodiment 200.1±19.3
5 groups of embodiment 196.2±17.6
6 groups of embodiment 199.5±18.5
As can be seen from Table 1, specific embodiment 1-6 group is compared with Normal group, and weight has notable difference.
Table 2 to rat total cholesterol (TC) and triglycerides (TG) influence (N=10)
Group Total cholesterol (mmol/L) Triglycerides (mmol/L)
Normal group 2.39±0.29 1.56±0.50
Example 1 group 2.17±0.28 1.38±0.38
2 groups of embodiment 2.15±0.23 1.35±0.35
3 groups of embodiment 2.11±0.25 1.23±0.33
4 groups of embodiment 1.95±0.22 1.26±0.29
5 groups of embodiment 1.86±0.23 1.13±0.23
6 groups of embodiment 1.96±0.21 1.16±0.25
As shown in Table 2, Examples 1 to 6 group compared with the control group, the total cholesterol and glycerol three of Examples 1 to 6 group rat Ester is substantially reduced.
Experimental example 2 improves diarrhea situation observation experiment
One, the general information of experimental subjects: using 22 habitual diarrhea persons for the treatment of, wherein male 16, female 6；Age The maximum 61 years old, youngest person 25 years old.
Two, treatment method:
Usage and dosage: three times a day, 10 grams every time, warm water takes 9 sample of the embodiment of the present invention.
The course for the treatment of: a month as a course for the treatment of, treats 3 courses for the treatment of altogether.
Three, the standard of curative effect evaluation
Recovery from illness: sign and symptom improve completely, and stool is completely normal, in high spirits.
Effective: sign and symptom significantly improve, and defecate normal, and spirit is very well.
Effective: sign and symptom have change, and stool significantly improves.
Invalid: sign is curved without changing, and sumptom is the same as before.
Five, result:
It treats within 3 months, wherein recovery from illness 8, effective 7, effective 5, invalid 2, total effective rate is up to 91%.As a result table Bright, the present invention has remarkable result to habitual diarrhea person.
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that without departing substantially from of the invention Many other change and modification can be made in the case where spirit and scope.It is, therefore, intended that in the following claims Including belonging to all such changes and modifications in the scope of the invention.

Claims (10)

1. a kind of solid beverage formula, which is characterized in that the solid beverage formula contain black fungus extract, oligofructose, Inulin, probiotic powder.
2. solid beverage formula according to claim 1, which is characterized in that the solid beverage formula further includes that buckwheat is low Poly- peptide.
3. solid beverage formula according to claim 2, which is characterized in that according to parts by weight, the black fungus extracts 200~500 parts of object, 60~200 parts of oligofructose, 30~80 parts of inulin, 10~90 parts of probiotic powder, buckwheat oligopeptide 30~80 Part.
4. solid beverage formula according to claim 2, which is characterized in that according to parts by weight, the black fungus extracts 300 parts of object, 100 parts of oligofructose, 50 parts of inulin, 50 parts of probiotic powder, 50 parts of buckwheat oligopeptide.
5. solid beverage formula according to claim 5, which is characterized in that the probiotic powder be lactobacillus plantarum and/ Or lactobacillus acidophilus and/or bifidobacterium lactis.
6. solid beverage formula according to claim 5, which is characterized in that the probiotic powder is lactobacillus plantarum: thermophilic Lactobacillus lactis: bifidobacterium lactis=3:2:5.
7. a kind of preparation method of solid beverage as claimed in claim 6, which is characterized in that each material of recipe quantity is weighed, by normal The production of regulation Preparation Method.
8. solid beverage formula according to claims 1 to 7, which is characterized in that the solid beverage formula be made powder, Tablet, capsule, granule or oral solution.
9. a kind of preparation method of solid beverage formulas described in any item according to claim 1~7, which is characterized in that use Dry process production, comprising the following steps: crushing, sieving, premixing, total mix, packing, packaging.
10. one kind solid beverage formula as described in any one of claim 1~7 in preparation weight-reducing or improves diarrhea or adjustment flora Application in food or Special food or drug.
CN201910354913.6A 2019-04-29 2019-04-29 A kind of black fungus extract solid drink formula and preparation method thereof for losing weight, improving diarrhea, adjust flora Pending CN110024932A (en)

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