CN108968037A - Senile dementia full nutrition formula food - Google Patents

Abstract

The present invention provides the specific full nutritional formulas that patients of senile dementia is eaten.The formula is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with the constitutive character of patients of senile dementia, the research achievements such as advanced physiology, medicine, nutrition and the clinical application of comprehensive nowadays American Harvard University, the marrow of the Traditional Chinese Medicine according to " middle residence that disappears is mended ", " balanced tone " theoretical (the dirty people having the same aspiration and interest of liver,spleen,kidney three is main principle) develop.The product uses the Chinese medical extract essence of a variety of dual-purpose of drug and food, a variety of probiotics, small peptide for primary raw material, it is mixed using prebiotics, carbohydrate, amino acid, fatty powder, haematococcus pluvialis, multivitamin and minerals as auxiliary material, it can be used as the nutritional need that single source of nutrition meets patients of senile dementia, there are also Bushen Yizhi benefiting qi and nourishing blood, dissipating phlegm for resuscitation and the full nutrition formula food for improving immunity.

Description

Senile dementia full nutrition formula food

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and food technology fields, specifically by the tradition of " Chinese medicine of integration of drinking and medicinal herbs " Chinese medicine marrow theory and " multiple probiotics " combine, and add with small peptide, prebiotics, amino acid, carbohydrate, rouge Fat, multi-vitamins, composite mineral matter are senile dementia full nutrition formula food made of auxiliary material.

Background technique

Senile dementia is senescence phase and the common one group of chronic progressive neurodegenerative disease of presenium, is the elderly Common disease and frequently-occurring disease in group.In China, the dementia incidence of over-65s crowd is about 7.5%, 85 years old or more group Incidence be even more be more than 40%.Among these, Alzheimer disease (Alzheimer ' s disease, AD) patient has accounted for always 70% or so of dementia patient populations, it has also become the important lethal of cardiovascular and cerebrovascular disease and malignant tumour is only second in the elderly Disease.Cognitive function, sociability and the self care ability of dementia patients are damaged in various degree, give patient home and society All bring very big burden.Clinically with memory disorders, aphasia, appraxia, agnosia, the damage of visual space technical ability, dysfunction is executed And the performance of the generalized dementias such as personality and behavior change is characterized, the cause of disease is unknown so far.According to cognitive ability and physical function Deterioration degree AD can be divided into three periods, be divided into mild dementia phase, moderate dementia phase and severe dementia three phases；

The theoretical basis of 1 kidney treating therapy.There is no the records about this disease of senile dementia in Chinese medical book, according to it Disease symptom, it is believed that it is in close relations with disease such as " amnesia " " dementia " " forgetful " " melancholia " " dementia " in traditional Chinese medicine.Ancient Chinese medicine doctor The etiology and pathogenesis that understanding to " dementia " " dementia " etiology and pathogenesis is system research today AD has established important foundation." book on Chinese herbal medicine is standby Want " in point out: " memory of people is all brain, and children are forgetful, and brain is less than;Old man forgetter, cerebral cecaying." " medical center changes It is wrong " in also mention: " Nian Gaowu memory person, brains are gradually empty." marrow is kidney essense, lid kidney storing essence, essence can give birth to marrow and fill brain;People is to old Year, half of YIN QI consumed, caused by liver and kidney deficiency, vital essence is insufficient, and brains are then difficult metaplasia.Just have in " Ling Shu Miraculous Pivot or Divine Axis sea opinion ": " brain being the marrow sea ... Marrow sea deficiency then vertigo and tinnitus, shin acid vertigo, mesh is without finding, reposal of slacking off " record.The appearance of cognitive disorder, normal companion's tinnitus cerebri, Dizziness, soreness and weakness of waist and knees, One's eyesight is restrained, slow in reacting, burnout think the kidney deficiency such as sleeping.So this disease cause of disease is kidney essence deficiency, Brains are difficult metaplasia, and brain is gradually empty, then refreshing machine appraxia, so that dull-witted.Its sick position is in the viscera functions such as brain and the heart, liver,spleen,kidney Lack of proper care related, and wherein especially with kidney be it is most important.Based on this, most doctors treat this disease using kidney tonifying as it in weight in recent years Weight；

2 clinical treatments.Li Zhichao thinks that senile dementia position in brain, but is kidney deficiency at all, treats based on kidney tonifying, uses Dihuang drink plus-minus treatment, observes 18 summary discoveries, and total effective rate is 94. 9%.Though Ji Tiezheng thinks that the sick position of this disease exists Brain, but it is at all dirty in liver kidney two, and The liver and the kidney have a common source, and treatment is when supporting essence to enrich blood, and dihuang drink function is in kidney tonifying, but liver loses benefit, So its control group 40 gives dihuang drink treatment, basis adds Qibao Meiran Dan and takes synergy of filling a vacancy herein for treatment group 38 Function, after 3 months observation discovery treatment group's total effective rate be 85. 0%, control group total effective rate be 55. 0%；

For food of special nutrients, there are corresponding regulation and development and application in developed countries such as the U.S., European Union；And China Wholefood clear stipulaties in GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: 2.1.1 full nutrition formula food: it can be used as the special medicine purposes formula that single source of nutrition meets target group's nutritional need Food；2.1.2 specific full nutritional formulas: it can be used as single source of nutrition and meet target group in specified disease or medicine shape The special medicine purposes formula food of nutritional need under condition；

Traditional Chinese medicine thinks: " spleen (i.e. digestive system) is the foundation of acquired constitution ", stomach health are health sheets, human nutrition 99% needs by intestinal absorption, and intestinal bowel disease is also source of ten thousand diseases；But with age, profitable strain (probiotics) in enteron aisle Ratio gradually decreases；If Bifidobacterium Bifidum accounts for 98% in infant period, 5% is only accounted for after 10%, 65 years old is down to when to the middle age；People gets over Always, probiotics is fewer, and function of intestinal canal is also gradually reduced therewith, more and more studies have shown that normal floras in human consumption, exempt from Epidemic disease and disease-resistant etc. there are many irreplaceable roles；The change and a variety of diseases, especially enteron aisle disease of intestinal flora composition The occurrence and development of disease are closely related, and find from existing clinical research: probiotics can play adjusting intestinal flora, control enteritis Disease effect is that one kind safely and effectively intervenes adjusting method；

The relationship of Dysbiosis and senile dementia: experiment and clinical card neuron paths and Tiny ecosystem have substantial connection, Intestinal flora can adjust corticocerebral gene expression, especially Bacillus acidi lactici, mainly include lactobacillus plantarum, short bifid bar Bacterium, bifidobacterium longum etc. adjust intestinal flora composition, can generate positive influence to neuron paths, and then delay old silly Slow-witted process.Though direct probiotic oral has certain effect, since probiotics can not be colonized in enteron aisle, and stops, accounts for Position seldom, is easy to run off, and withdraws that rear harmful bacteria is easy to recur, and associated patient needs to take for a long time, and treatment cycle is long, often multiple after use Hair rate is very high；For shorten associated patient treatment cycle, reduce be discontinued after recurrence rate, this team by over nearly 3 years to prebiotic Bacterium be colonized in enteron aisle mechanism key technology research, make great efforts seek improve probiotics be colonized in enteron aisle " integration of drinking and medicinal herbs it Chinese medicine " compound, it is contemplated that several key elements that probiotics is colonized in enteron aisle: the presence of prebiotics can play field planting effect, The reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. for improving probiotic cell, are based on above-mentioned element, this seminar is from tens of Suitable food materials of screening in kind of " Chinese medicine of integration of drinking and medicinal herbs ", add prebiotics, after L-Glutamine etc., have to external source probio Very strong field planting effect, the prescription selection for probiotics in enteral microecological formulation provide experimental basis；

Currently on the market favorably to food-borne small peptide be primary raw material, add the mushroom, dried orange peel, fructus lycii, mountain of dual-purpose of drug and food Extract, multi-vitamins and the minerals of medicine, Poria cocos, rhizoma polygonati etc. form compound prescription, and there are also be main former using probiotics The product of material combines the constitutive character of patients of senile dementia but without discovery, and the marrow according to Traditional Chinese Medicine is theoretical, because of people And it is different, gold compatibility is using the Chinese medical extract essence of a variety of dual-purpose of drug and food, a variety of probiotics, small peptide as primary raw material, with prebiotic Member, carbohydrate, amino acid, fat, multivitamin and several mineral materials are full nutrition formula food, spy made of auxiliary material Determine full nutrition formula food or similar products.

Goal of the invention

It is initiative by a variety of raising patients of senile dementia the purpose of the present invention is on inheriting Chinese medicine marrow theory treatment method The probiotics of immunity and the extract of " Chinese medicine of integration of drinking and medicinal herbs " compound combine, add with small peptide, amino Acid, carbohydrate, fat, multivitamin, several mineral materials are auxiliary material, and can not only supplement patients of senile dementia must Nutrient is needed, body nutrition condition is improved, moreover it is possible to body function is adjusted using the function factor in dual-purpose of drug and food Chinese herbal medicine, it is prebiotic Bacterium can play adjusting intestinal flora, and toxic side effect is small, safe and effective, and the acceptable suitable patients of senile dementia food of people Specific full nutritional formulas.

Summary of the invention

The requirement of this R&D team basis " special medicine purposes formula food general rule ", in conjunction with the body of patients of senile dementia Matter feature, the research achievements such as advanced physiology, medicine, nutrition and the clinical application of comprehensive nowadays American Harvard University, foundation The marrow of the Traditional Chinese Medicine of " middle residence that disappears is mended ", " balanced tone " is theoretical (the dirty people having the same aspiration and interest of liver,spleen,kidney three is main principle), use 3 kinds with The Chinese medical extract essence of upper dual-purpose of drug and food, a variety of probiotics, small peptide are primary raw material, with prebiotics, carbohydrate, amino Acid, fat, multivitamin and minerals auxiliary material, can be used as the nutrition that single source of nutrition meets patients of senile dementia Demand there are also Bushen Yizhi, benefiting qi and nourishing blood, dissipating phlegm for resuscitation and improves the full nutrition formula food of efficacy of immunity, specific full battalion Support formula food or non-whole nutritional formula food (compound prescription being combined into)；

1, the main component of inventive formulation

Chinese medical extract is to be adjusted to together according to the constitutive character of patients of senile dementia from the liver,spleen,kidney three in theory of traditional Chinese medical science is dirty Main principle adjusts body function using the function factor in dual-purpose of drug and food Chinese herbal medicine and builds up resistance, and chooses following several major class Drug carries out compatibility；Wherein: maca contains maca ene and macamide, and maca ene and macamide have good adjusting human body The effect of hormone secretion has and alleviates climacteric syndrome, improves sub-health state effect.Cordyceps militaris enters lung kidney two warp, can Tonifying lung yin, and energy kidney-replenishing, cure mainly kidney deficiency, impotence and seminal emission, soreness of waist and knee joint, eak after being ill, chronic cough is weak, phthisical cough phlegm blood, spontaneous perspiration Night sweat etc..Raspberry has liver-kidney tonifying, and astringent sperm contracting urine cures mainly impotence and premature ejaculation, emission and spermatorrhea effect.Ginseng can reinforce vital energy, Veins takes off admittedly reinforces the spleen to benefit the lung, shengjin nourishing, tranquilize the mind and promote the intelligence.Line leaf broom top has the effect of calm central nervous system, be suitble to There are allergy, headache, sleep disorder, insomnia, nervous, slight melancholia effect.Rhizoma polygonati is sweet in flavor mild-natured, and energy boosting qi and nourishing yin is good for Spleen, moistening lung, kidney-nourishing.Fructus lycii is sweet in flavor, mild-natured, nourishing the liver, nourshing kidney, moistening lung, cures mainly caused by liver and kidney deficiency, has a dizzy spell, is visually unclear, waist Knees soreness.Poria cocos medicinal peace, contained pachymic acid have the function of strengthen immunity, antitumor and calm, hypoglycemic etc..Meat Osmanthus extremely hot in nature, it is acrid flavour, sweet, control the Yang-function insufficiency of kidneyzang, cold weak pulse of limb, yang depletion collapse, abdominal pain diarrhoea, cold hernia renal mass, waist and knee crymodynia.Wild jujube Benevolence is sweet in flavor acid flat, and energy nourishing heart tonifying liver, arrest sweating, is promoted the production of body fluid at antitoxic heart-soothing and sedative.Contain the nutrition such as tannic acid, fatty acid, malic acid in mulberry fruit Substance can help the digestion of fat, protein and starch, therefore the function for having strengthening the spleen and stomach aid digestion.Walnut kernel is containing more protein And unsaturated fatty acid necessary to human nutrition, energy nursing brain cells enhance brain function.Radix Glycyrrhizae is sweet in flavor mild-natured, can invigorate the spleen and benefit qi, Clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；

Chinese medical extract of the present invention refer to maca, Cordyceps militaris, raspberry, ginseng, line leaf broom top, rhizoma polygonati, fructus lycii, Peach kernel, Poria cocos, semen ziziphi spinosae, eucommia Bark male flower, mulberry fruit, walnut kernel, rhizoma zingiberis, Radix Glycyrrhizae, dried orange peel, turmeric, cortex cinnamomi, Chinese yam, cloves are wherein 3 kinds or more or all, extracted using biological enzymolysis or prehydrolysis SBE and microencapsulation, it is spray-dried and freeze-drying Mixture after extract；

2, a variety of probiotics

So that probiotics is largely reached enteron aisle by the strong acid environment of stomach, to promote the proliferation of probiotics, adjusts the micro- life of enteral State balance, promotes the absorption to microelement, enhances taste motor function, accelerates the absorption of drug effect, improve the micro- of mucous membrane surface The balance of biota or enzyme, or stimulation body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity； Xing etc. pre-processes law during ischemia/reperfusion rat with Bifidobacterium and Bacillus acidi lactici, can be substantially reduced intestinal endotoxemia Horizontal and preventing liver injury generation；Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, there is research It does not absorb that rifamycin antibiotic former times is bright (rifaximin) using enteron aisle, passes through the life for inhibiting urease-producing in enteron aisle and producing ammonium bacteria It is long, to build up resistance；

A variety of probiotics of the present invention all use the probiotics after microencapsulation, in addition to streptococcus thermophilus, wherein bifid Bacillus: refer to bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, long bifid Bacillus is one of, several or whole mixes；Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, bulgarian milk bar Bacterium, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, Lactobacillus reuteri, lactobacillus plantarum, lactobacillus paracasei, Yue Shi lactobacillus are one of, several or whole mixes；

3, small peptide

As oligopeptide refers to the small molecule egg of the separation and Extraction from animal or vegetable protein using bio-enzyme engineering technology White matter, average molecular weight hereinafter, soluble easily in water, to acid, thermostabilization, can be not required to direct by digestion in 1000Dalton It absorbs, bioavailability is high, is absorbing and using upper better than free amino acid and complete protein, can be applied to protein In supplement, particularly with the low crowd of abilities of digestive and absorption, small peptide is splendid nitrogen source, in addition to trophic function, small peptide Also there are a series of physiological active functions: improving the digestion and absorption function of small intestine, enhance immunity of organisms, it is anti-oxidant, it is auxiliary Adjusting blood glucose is helped, auxiliary adjustment of blood fat, aided blood pressure-lowering is anti-radiation, promotes mineral absorption, enhances dual-purpose of drug and food Chinese herbal medicine The function and effect of middle function factor；

Small peptide of the present invention refers to ocean fish oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, albumen egg White peptide is one of, several or whole mixes；

4, prebiotics

To promote probiotics intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most of enteron aisle spoilage organisms, But beneficial bacteria in human body can be promoted --- lactobacillus, Bifidobacterium growth and breeding, so as to inhibit spoilage organisms to grow, Help to improve and maintain enteron aisle normal function；Long-term consumption can delay aging, defaecation, improve immunity, mitigation liver is born Load, the absorptivity for improving nutrient, can especially improve body to Metal Ions Absorptions such as calcium, iron, zinc；Optionally promote Into outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also metabolizable is the organic acids such as acid product such as lactic acid, makes colon pH Value reduces, and inhibits the growth of intestinal harmful bacillus；So that small enteral Water-Electrolyte is trapped in enteric cavity, generate height and ooze effect, stimulates intestines Wriggling causes laxative, to promote intestinal endotoxin and the discharge of other toxicants, lactulose can also be inactivated directly in enteron aisle Endotoxin reduces gut pH, has been widely applied to the treatment of enhancing child resistant；

Prebiotics of the present invention are 2 classes

A. there are very strong field planting effect prebiotics: fructus lycii, ginseng, Radix Glycyrrhizae, the extract of jerusalem artichoke, wood to external source probio Sugar, yeast are therein several or all mix；

B. common prebiotics: oligoisomaltose, oligofructose, soyabean oligosaccharides, xylo-oligosaccharide are one such, several or complete Portion's mixing；

Originally refer to that oligoisomaltose, stachyose, oligofructose, soyabean oligosaccharides, xylo-oligosaccharide are one such, several or complete Portion's mixing；

5, carbohydrate

Carbohydrate is made of three kinds of carbon, hydrogen and oxygen elements, it is that three kinds of main nutrition of thermal energy are provided for human body Most cheap nutrient in element, when intake is sufficient, in vivo can rapid oxidation energy is provided in time, avoid valuable protein For providing energy, carbohydrate be also the glycoprotein of cell membrane, nerve fiber glycolipid and convey hereditary information de- The important composition ingredient of oxygen ribonucleic acid (DNA), and the glycogen contained in carbohydrate, when it lays in abundance in liver When, the toxin that liver cell generates certain toxic chemical substances and various pathogenic microorganisms has stronger detoxification ability；

Carbohydrate of the present invention refers to glucose, fructose, galactolipin, lactose, L-arabinose, maltose, water-soluble Property dietary fiber, starch, glycogen be one such, several or all mixing；

6. amino acid

It is divided into essential amino acid and nonessential amino acid, is the basic unit for constituting protein, assigns the specific molecule of protein Structural form makes it have biochemical activity；Absorbing suitable methionine facilitates the metabolism of various sulfur-containing compounds in human body simultaneously And the methyl contained by it methylates to Toxic or drug and plays the role of removing toxic substances；Leucine can repair muscle, control Blood glucose processed, and energy is provided to bodily tissue, it is necessary to amino acid phenylalanine can inhibit cancer growth, and can reduce drug Toxic side effect, lysine can be improved the absorption and utilization of food protein, reaches balanced nutritious, enhancing development；Smart ammonia Acid helps the ammonia in blood being changed into urea and excrete out；For hyperammonemia, hepatic dysfunction etc. is powerful； Histidine reduces gastric acidity, mitigates the pain of gastrointestinal procedures, mitigates gestational period vomiting and scorching hot sense, inhibits by plant mind It festers through alimentary canal caused by anxiety, it is also powerful to anaphylactia, such as asthma；Tryptophan can prevent pellagra, Depression improves sleep and adjusts mood；

Amino acid of the present invention refers to L-Glutamine, tealeaves theanine, methionine, isoleucine, tyrosine, phenylpropyl alcohol ammonia Acid, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine are one such, several or whole mixes；

7. fatty powder

Fat is commonly called as grease, is made of carbon, hydrogen and oxygen element；It is both important composition part and the heat of tissue One of main matter of amount；Fat in food digests in stomach, most of after absorption to be changed into fat once again again；It is main Be distributed in around subcutis, omentum majus, mesenterium and kidney etc.；The trigalloyl that fat is made of glycerol and fatty acid Glyceride, wherein the molecule of glycerol is fairly simple, and the type of fatty acid and length is not identical；Fatty acid divides three categories: full With fatty acid, monounsaturated fatty acids, polyunsaturated fatty acid;The source of fat can divide following two kinds: animality source: animal The fat stored in vivo: such as lard, butter, sheep oil, fish oil, marrow, fat meat, cod-liver oil；Fat in animal cream: such as cream Deng；Vegetalitas source: vegetablefats source is mainly extracted out of fruit in plant, such as sesame, sunflower seed, tea life, core Peach, pine nut, soya bean etc.；It is compound by a variety of fatty acid, adjust saturated fatty acid, monounsaturated fatty acids, polyunsaturated fat The content ratio of acid is that the ratio of 1:1:1, ω -6 and ω -3 are 10:1 ~ 2:1, preferably 5:1 ~ 2:1, preferred 2:1；It has been especially added with 2- 8 parts of omega-fatty acid, source include addition embedding material after the combination of one or both of fish oil, algae oil, are obtained through homogeneous Then emulsion is obtained fatty powder using screening by being dried in spray drying device by emulsion；

Fat of the present invention refer to MCT powder, alpha-linolenic acid, linoleic acid, corn oil, soybean oil, peanut oil, sunflower oil, Olive oil, linseed oil, embryo oil, phosphatidylserine are one such, several or whole mixes；

8. vitamin and mineral

Vitamin and mineral is nutrient needed by human, and the vitamin added in the present invention is that vitamin and mineral is people Nutrient necessary to body；

The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K₁, vitamin C, dimension Raw element B₁, vitamin B₂, vitamin B₆, vitamin B₁₂, niacin, folic acid, pantothenic acid, choline, biotin be one such, Ji Zhonghuo All mixing；

The minerals added in the present invention are that calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum are therein A kind of, several or whole mixing, minerals of the present invention are added to the organic or inorganic compound of the minerals；

9. the present invention is with microcapsules, biological enzymolysis, prehydrolysis SBE, spray drying and freeze-drying integrated innovation, the industry of composition The key technology that metaplasia produces；Microencapsulation protection technique efficiently solves oral process high temperature and strong acid gastric juice to prebiotic The inactivation of bacterium；Using three layers of buried microcapsules technology of protein, then with extracted through biological enzymolysis or prehydrolysis SBE technology and micro- glue Encapsulated treated Chinese medical extract is uniformly mixed, and is coexisted with solution " multiple probiotics " and " Chinese medicine of integration of drinking and medicinal herbs " component Problem has certain resistant to high temperatures and strong acid characteristic, is conducive to probiotics and is stopped by oral pass through in gastric juice arrival enteron aisle The effect of staying field planting, making product greatly improves compared with the similar product of market；

10. various ingredients to be uniformly mixed to solid beverage, the granule that powdery is made using above-mentioned integrated innovation technique, and dispense It directly drinks or is taken in through nasal feeding after (45 DEG C) of about 150ml warm water dissolutions at 10g/ packet；Appropriate attached material can also be added Capsule, tablet is made or be added brown sugar and black sesame powder be made biscuit etc. quickly, instant food convenient for it is outgoing carry it is edible, if doing It is then saved at beverage spray-dried, adds auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal daily Each 1 bottle of drink, all operations are in the clean dried environment for meeting " special medicine purposes formula food Good Manufacture Practice " requirement Interior progress；

The characteristic of this formula full nutrition formula food and its following aspects is mainly manifested in the effect of body:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", the constitution in conjunction with patients of senile dementia is special Sign, the research achievements developments such as advanced physiology, medicine, nutrition and the clinical application of comprehensive nowadays American Harvard University, because People and different, gold compatibility；

2. the marrow of the Traditional Chinese Medicine of present invention foundation " middle residence that disappears is mended ", " balanced tone " is theoretical, (liver,spleen,kidney three is dirty to be adjusted to together Main principle), use the Chinese medical extract essence of a variety of dual-purpose of drug and food, a variety of probiotics, small peptide for primary raw material, with prebiotics, Carbohydrate, amino acid, multivitamin and minerals are auxiliary material, and the organic assembling of various ingredients carries out various functions Fusion, and pass through the synergistic effect between effective component, humidification effect；

3. there is effective absorbency, using inventive formulation, food of the various components using suitable ratio collocation preparation, warp It is in isotonic state after a certain amount of water dissolution, small intestine can be reached quickly through stomach, absorb quickly, completely, can supplement rapidly old age Nutrition needed for Dementia patients；

4. not only being mentioned using the extract of various dual-purpose of drug and food Chinese herbal medicines containing multiple functions active constituent in inventive formulation The high concentration of function factor, reduces the intake of various impurity, helps to mitigate liver kidney burden, have enhancing resistance of human body Effect there are also Bushen Yizhi, benefiting qi and nourishing blood, dissipating phlegm for resuscitation and improves efficacy of immunity；

5. probiotics contained in inventive formulation, a variety of probiotics can safeguard enteron aisle normal bacteria colony balance, inhibit disease The growth of opportunistic pathogen prevents gastrointestinal disorders etc., and vitamin, amino acid are synthesized in enteron aisle and improves absorption of the body to calcium ion, Enhance human immunologic function, prevent the side effect of antibiotic, improves host to the tolerance of radioactive ray, lactobacillus dramatically increases intestines Mucosal immunity globulin A (SIgA) content has adjustment effect to body intestinal mucosa local immunity, adjusts stomach, intestines Tiny ecosystem, energy The utilization rate of calcium, phosphorus, iron is improved, promotes the absorption of iron and vitamin D, the absorption of cholesterol can also be reduced；

6. inventive formulation food is using the food-borne bioactive short peptide in a variety of sources as nitrogen source, because small peptide is not required to digestion i.e. It is absorbable, it is more advantageous to the utilization of body, twitch, hyperactivity patient's negative nitrogen balance, and food-borne small peptide can be effectively improved The structure and function that intestinal epithelial cell can be improved improves the absorbability of intestinal mucosa；

7. prescription uses what this team was studied by being colonized the key technology of mechanism over nearly 3 years in enteron aisle to probiotics Achievement improves " Chinese medicine of integration of drinking and medicinal herbs " compound that probiotics is colonized in enteron aisle, and the presence for combining prebiotics, which can be played, to be determined The elements such as the enteron aisle adhesive capacity of plant effect, the reduction of intestinal pH environment and raising probiotic cell, therefore the food formula Composition greatly strengthens the field planting effect to external source probio；

8. prebiotics contained in inventive formulation inhibit the growth of spoilage organisms by the growth and breeding of promotion enteral probiotics, One of protective barrier is formed in intestinal mucosal surface simultaneously, damage of the enteron aisle spoilage organisms to intestinal mucosa can be resisted, reducing enteral has The absorption of evil substance, can also promote intestines peristalsis, accelerate the discharge of enteral residuals, can prevent constipation, and pass through Promote the growth and breeding of beneficial bacteria of intestinal tract that immunity of organisms also can be enhanced, small peptide, carbohydrate and active polysaccharide etc. are biological Active material has synergistic effect；

9, carbohydrate contained in inventive formulation is that three kinds of main nutrients of thermal energy are provided for human body, in vivo Can rapid oxidation energy is provided in time, avoid being used to valuable protein to provide energy, carbohydrate is also cell membrane The important composition ingredient of glycoprotein, the glycolipid of nerve fiber and the DNA (DNA) to convey hereditary information, and carbon The glycogen contained in hydrate, when it lays in abundance in liver, liver cell is to certain toxic chemical substances and various causes The toxin that sick microorganism generates has stronger detoxification ability；

10, amino acid contained in inventive formulation is the basic unit for constituting protein, assigns the specific molecule knot of protein It is configured state, makes it have biochemical activity, facilitates the metabolism of various sulfur-containing compounds in human body and the methyl contained by it is to having Poisonous substance or drug are methylated and play the role of removing toxic substances, and muscle can be repaired, and control blood glucose, and provide energy to bodily tissue Amount, also can be improved the absorption and utilization of food protein, reaches balanced nutritious；

11, inventive formulation food contains multivitamin and minerals, can supplement rapidly micro needed for patients of senile dementia Nutrient, small peptide is by further increasing the absorptivity of mineral matter element with after the chelating of calcium, iron, zinc etc.；

12, fatty in inventive formulation, maize germ oil, sunflower oil lack ω -3-PUFA rich in ω -6-PUFA；Olive Oil, tea-seed oil are rich in monounsaturated fatty acids (MUFA), can increase rouge while supplementing protein, micronutrient The intake of fat avoids the adverse effect of the high protein diets such as meat, egg.

Specific embodiment

Below by following embodiment, the invention will be further described, it will be helpful to understand the present invention；

Realize that the object of the invention senile dementia full nutrition formula food is the constitutive character to combine patients of senile dementia, according to It is theoretical according to the marrow of Traditional Chinese Medicine, it varies with each individual, gold compatibility is with the Chinese medical extract essence of 3 kinds or more dual-purpose of drug and food, a variety of Probiotics, small peptide are primary raw material, are with prebiotics, carbohydrate, amino acid, fat, multivitamin, several mineral materials Food made of auxiliary material；Bifidobacterium is selected from bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, baby Youngster Bifidobacterium, bifidobacterium longum one or more；Lactobacillus is selected from lactobacillus acidophilus powder, Lactobacillus casei, Bulgaria Lactobacillus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, rhamnose cream Bacillus, lactobacillus reuteri, lactobacillus plantarum, lactobacillus paracasei, Yue Shi lactobacillus one or more；Small peptide is selected from ocean The one or more of fish oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide；Prebiotics are selected from low Polyisomaltose, stachyose, oligofructose, the one or more of soyabean oligosaccharides, xylo-oligosaccharide；Amino acid be selected from methionine, Isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine, tea The one or more of leaf tea propylhomoserin；Fat is selected from MCT powder, alpha-linolenic acid, linoleic acid, corn oil, soybean oil, peanut oil, sunflower The one or more of seed oil, olive oil, linseed oil, embryo oil, phosphatidylserine；Vitamin premix be selected from vitamin A, Vitamin D, vitamin E, vitamin K₁, vitamin C, vitamin B₁, vitamin B₂, vitamin B₆, vitamin B₁₂, niacin, leaf One or more of acid, pantothenic acid, choline, biotin etc.；Mineral substance premix be selected from calcium, phosphorus, potassium, sodium, magnesium, iron, zinc, selenium, One or more of copper, manganese, iodine, fluorine, chromium, molybdenum etc.；

Embodiment one

It selects following formula and ratio to be made and is mixed for senile dementia full nutrition formula food: by following raw materials according and its use Amount is formulated: the extract of dual-purpose of drug and food: 15 parts of maca, 15 parts of Cordyceps militaris, 15 parts of raspberry, 15 parts of ginseng, line leaf goldspink Spend 15 parts, 15 parts of rhizoma polygonati, 15 parts of fructus lycii, 15 parts of peach kernel, 10 parts of Poria cocos, 10 parts of semen ziziphi spinosae, 10 parts of eucommia Bark male flower, mulberry fruit 10 Part, 10 parts of walnut kernel, 10 parts of rhizoma zingiberis, 8 parts of Radix Glycyrrhizae, 8 parts of dried orange peel, 8 parts of turmeric, 8 parts of cortex cinnamomi, 8 parts of Chinese yam, 8 parts of cloves；Bifid bar 75 parts of bacterium, 75 parts of lactobacillus, 40 parts of streptococcus thermophilus, 100 parts of L-Glutamine, 100 parts of small peptide, 100 parts of prebiotics, compound ammonia 100 parts of base acid, 100 parts of water-soluble dietary fiber, 150 parts of fatty powder, 10 parts of tealeaves theanine, 5 parts of phosphatidylserine, rain are raw 5 parts of haematococcus, 5 parts of multi-vitamins, 50 parts of composite mineral matter；

First by maca, Cordyceps militaris, raspberry, ginseng, line leaf broom top, rhizoma polygonati, fructus lycii, peach kernel, Poria cocos, wild jujube when production Benevolence, eucommia Bark male flower, mulberry fruit, walnut kernel, rhizoma zingiberis, Radix Glycyrrhizae, dried orange peel, turmeric, cortex cinnamomi, Chinese yam, cloves impregnate after be added cellulase, Pectase, papain and amylase, 1 mg/g substrate of enzyme dosage, pH value is 4.0, in 50 DEG C of enzymatic hydrolysis 3h, feed liquid It is spray-dried and be prepared into flour after extracting Chinese medicine essence with biological enzymolysis technology than 1:15, then add biological enzyme Solve extract small peptide, prebiotics, amino acid, water-soluble dietary fiber, MCT powder, alpha-linolenic acid, linoleic acid, multi-vitamins and It is carried out after minerals mixing pasteurization 1 hour, (bifidobacterium adolescentis, cream are double for the Bifidobacterium after then adding microencapsulation Discrimination bacillus, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum), lactobacillus (lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, lactobacillus plantarum, lactobacillus paracasei, Yue Shi lactobacillus), it is thermophilic Streptococcus and uniformly mixed solid beverage, the granule that powdery is made of the various ingredients mixed, and it is distributed into 10g/ packet, with about After (45 degree) of 150ml warm water dissolutions, directly drinks or taken in through nasal feeding；Appropriate attached material can also be added, capsule, tablet is made Or be added sweetener and black sesame powder be made biscuit etc. quickly, instant food carry edible convenient for outgoing, saved if being made into beverage It goes spray-dried, adds black sesame powder etc. less, be distributed into 50ml/ bottle, respectively drink 1 bottle within daily early, middle and late 0.5 hour after meal, institute There is operation to carry out in clean dried environment；

Embodiment two

Above-mentioned senile dementia full nutrition formula food is also an option that following formula and ratio are made and is mixed for old be crazy about Slow-witted disease full nutrition formula food: the extract of dual-purpose of drug and food: 18 parts of Cordyceps militaris, 18 parts of raspberry, 18 parts of ginseng, line leaf broom top 18 parts, 18 parts of rhizoma polygonati, 18 parts of fructus lycii, 18 parts of Poria cocos, 10 parts of semen ziziphi spinosae, 10 parts of eucommia Bark male flower, 10 parts of mulberry fruit, walnut kernel 10 Part, 10 parts of rhizoma zingiberis, 10 parts of Radix Glycyrrhizae, 10 parts of dried orange peel, 5 parts of turmeric, 5 parts of cortex cinnamomi, 5 parts of cloves；85 parts of Bifidobacterium, lactobacillus 55 It is part, 50 parts of streptococcus thermophilus, 100 parts of L-Glutamine, 100 parts of small peptide, 100 parts of prebiotics, 100 parts of compound amino acid, water-soluble It is 100 parts of dietary fiber of property, 150 parts of fatty powder, 10 parts of tealeaves theanine, 5 parts of phosphatidylserine, 5 parts of haematococcus pluvialis, compound 5 parts of vitamin, 50 parts of composite mineral matter；

Embodiment three

Above-mentioned senile dementia full nutrition formula food is also an option that following formula and ratio are made and is mixed for old be crazy about Slow-witted disease full nutrition formula food: the extract of dual-purpose of drug and food: 18 parts of Cordyceps militaris, 18 parts of raspberry, 18 parts of ginseng, line leaf broom top 18 parts, 18 parts of rhizoma polygonati, 18 parts of fructus lycii, 18 parts of Poria cocos, 10 parts of semen ziziphi spinosae, 10 parts of eucommia Bark male flower, 10 parts of mulberry fruit, walnut kernel 10 Part, 10 parts of rhizoma zingiberis, 10 parts of Radix Glycyrrhizae, 10 parts of dried orange peel, 5 parts of turmeric, 5 parts of cortex cinnamomi, 5 parts of cloves；85 parts of Bifidobacterium, lactobacillus 55 It is part, 50 parts of streptococcus thermophilus, 100 parts of L-Glutamine, 100 parts of small peptide, 100 parts of prebiotics, 100 parts of compound amino acid, water-soluble Property 100 parts of dietary fiber, 150 parts of fatty powder, 5 parts of multi-vitamins, 50 parts of composite mineral matter.

Claims (5)

1. senile dementia full nutrition formula food, it is characterised in that its material composition content includes following group by weight Point: the extract of dual-purpose of drug and food: 10-20 parts of maca, 10-20 parts of Cordyceps militaris, 10-20 parts of raspberry, 10-20 parts of ginseng, line leaf 10-20 parts of broom top, 10-20 parts of rhizoma polygonati, 10-20 parts of fructus lycii, 10-20 parts of peach kernel, 8-15 parts of Poria cocos, 8-15 parts of semen ziziphi spinosae, 8-15 parts of eucommia Bark male flower, 8-15 parts of mulberry fruit, 8-15 parts of walnut kernel, 8-15 parts of rhizoma zingiberis, 5-10 parts of Radix Glycyrrhizae, 5-10 parts of dried orange peel, turmeric 5-10 parts, 5-10 parts of cortex cinnamomi, 5-10 parts of Chinese yam, 5-10 parts of cloves；50-100 parts of (youth bifids of Bifidobacterium after microencapsulation Bacillus, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum), lactobacillus 50-100 Part (lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, acidified milk Bacillus, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, lactobacillus plantarum, lactobacillus paracasei, Yue Shi lactobacillus), 20-60 parts of streptococcus thermophilus, 50-150 parts of L-Glutamine, small peptide 50-150 parts of (ocean fish oligopeptides, sea Foreign bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide), prebiotics 50-150 parts of (oligoisomaltoses, wood Sugar, oligofructose, soyabean oligosaccharides, xylo-oligosaccharide), 50-150 parts of compound amino acid (methionine, isoleucine, tyrosine, Phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine), water-soluble dietary fiber 50- 150 parts, fatty powder 100-200 parts of (MCT powder, alpha-linolenic acid, linoleic acid, corn oil, soybean oil, peanut oil, sunflower oil, olives Olive oil, linseed oil, embryo oil), 5-15 parts of tealeaves theanine, 5-8 parts of phosphatidylserine, 3-7 parts of haematococcus pluvialis, dimension life Plain premix (vitamin A, vitamin D, vitamin E, vitamin K₁, vitamin C, vitamin B₁, vitamin B₂, vitamin B₆、 Vitamin B₁₂, niacin, folic acid, pantothenic acid, choline, biotin) 5 parts；Mineral substance premix (calcium, phosphorus, potassium, sodium, magnesium, iron, zinc, selenium, Copper, manganese, iodine, fluorine, chromium, molybdenum) 50 parts；

First by maca, Cordyceps militaris, raspberry, ginseng, line leaf broom top, rhizoma polygonati, fructus lycii, peach kernel, Poria cocos, wild jujube when production Benevolence, eucommia Bark male flower, mulberry fruit, walnut kernel, rhizoma zingiberis, Radix Glycyrrhizae, dried orange peel, turmeric, cortex cinnamomi, Chinese yam, cloves impregnate after be added cellulase, Pectase, papain and amylase, enzyme dosage 0.2-2 mg/g substrate, pH value is 3.0-5.0, at 40-60 DEG C 1~5h is digested, solid-liquid ratio 1:10~20 are spray-dried and be prepared into powder after extracting Chinese medicine essence with biological enzymolysis technology Shape substance, then add small peptide, prebiotics, amino acid, water-soluble dietary fiber, fatty powder, haematococcus pluvialis, multi-vitamins and It is carried out after minerals mixing pasteurization 1 hour, (bifidobacterium adolescentis, cream are double for the Bifidobacterium after then adding microencapsulation Discrimination bacillus, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum), lactobacillus (lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, lactobacillus plantarum, lactobacillus paracasei, Yue Shi lactobacillus), it is thermophilic Streptococcus and uniformly mixed solid beverage, the granule that powdery is made of the various ingredients mixed, and it is distributed into 10g/ packet, with about After (45 DEG C) of 150ml warm water dissolutions, directly drinks or taken in through nasal feeding；Appropriate attached material can also be added, capsule, tablet is made Or be added sweetener and black sesame powder be made biscuit etc. quickly, instant food carry edible convenient for outgoing, saved if being made into beverage It goes spray-dried, adds black sesame powder etc. less, be distributed into 10-65ml/ bottle, respectively drink 1 within daily early, middle and late 0.5 hour after meal Bottle, all operations carry out in clean dried environment.

2. senile dementia full nutrition formula food according to claim 1 further includes following component by weight: medicine Eat dual-purpose extract: maca, Cordyceps militaris, raspberry, ginseng, line leaf broom top, rhizoma polygonati, fructus lycii, peach kernel, Poria cocos, wild jujube Benevolence, eucommia Bark male flower, mulberry fruit, walnut kernel, rhizoma zingiberis, Radix Glycyrrhizae, dried orange peel, turmeric, cortex cinnamomi, Chinese yam, cloves all mix.

3. above-mentioned senile dementia full nutrition formula food further includes that the dual-purpose of drug and food Chinese herbal medicine extract and new food are former Material are as follows: maca, Cordyceps militaris, raspberry, ginseng, line leaf broom top, rhizoma polygonati, fructus lycii, peach kernel, Poria cocos, semen ziziphi spinosae, Cortex Eucommiae are male Flower, mulberry fruit, walnut kernel, rhizoma zingiberis, Radix Glycyrrhizae, dried orange peel, turmeric, cortex cinnamomi, Chinese yam, cloves, haematococcus pluvialis all mix.

4. senile dementia full nutrition formula food according to claim 1, being characterized in that can according to formula mixing Prepare powdering, graininess, capsule shape, tablet shape, beverage based food.

5. senile dementia full nutrition formula food according to claim 1, is characterized in that Chinese medicine zymolysis technique, using fibre Tie up the conspiracy relation that plain enzyme, pectase, papain and amylase are formed between one group of enzyme, enzyme dosage 0.2-2 mg/g Substrate, pH value is 3.0-5.0, in 40-60 DEG C of 1~5h of enzymatic hydrolysis, solid-liquid ratio 1:10~20.