CN104839678A - Medical formula food for people with nephrosis - Google Patents
Medical formula food for people with nephrosis Download PDFInfo
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- CN104839678A CN104839678A CN201510171573.5A CN201510171573A CN104839678A CN 104839678 A CN104839678 A CN 104839678A CN 201510171573 A CN201510171573 A CN 201510171573A CN 104839678 A CN104839678 A CN 104839678A
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Abstract
The invention belongs to the technical field of medicine and food homology formula and new resource food, and more specifically provides a medical formula food, a specific medical formula food, or an unspecified medical formula food for patients with nephrosis. The medical formula food is prepared based on requirements of <special medical formula food general principles>, via combination with physical characteristics of patients with nephrosis, via combination of a plurality of traditional Chinese medicine raw materials which can be taken as both medicines and food based on traditional Chinese medicine quintessence theories; and is prepared via mixing of a plurality of traditional Chinese medicine extract essence; a plurality of microencapsulated probiotics; oligopeptides, prebiotics, amino acids, and carbohydrates obtained via biological enzymolysis extraction; grease with healthcare functions; and a plurality of vitamins and mineral matters. The traditional Chinese medicine extract essence is obtained via prehydrolysis SBE technology from traditional Chinese medicine raw materials which can be taken as both medicines and food. The medical formula food can be taken as a signal nutrition source so as to satisfy nutrient requirements of patients with nephrosis, and is capable of invigorating the kidney and strengthening Yang, increasing semen and blood, nourishing liver and kidney, strengthening tendon and bone, securing essence and reducing urination, and treating nephrosis.
Description
Technical field
The invention belongs to integration of drinking and medicinal herbs class formula and new resource food technical field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds with small peptide, prebiotics, amino acid, carbohydrate, the medical science formula food preventing and treating ephrosis, certain medical formula food or the non-medical formula food that have the grease of health care, B B-complex, composite mineral matter to make for auxiliary material.
Background technology
CKD (CKD) defines: the chronic Renal Structure that a variety of causes causes and dysfunction (kidney damage medical history is greater than 3 months), comprise kidney GFR normal and abnormal pathology damage, blood or urinary fractions abnormal, and imaging examination is abnormal, or unknown cause GFR decline (<60ml/min 1.73m
2) more than 3 months, be CKD, cause the disease of CKD to comprise various former, the glomerulonephritis of secondary, renal damage and renovascular pathology etc., CKD can be divided into for 5 phases according to GFR, early detection and early intervention can reduce the complication of CKD patient significantly, obvious raising survival rate, for the treatment of CKD, comprises the treatment of protopathy, the progress that the process of various hazards and postponing chronic kidney function are incomplete, when CKD patient progress to 5 phase, should carry out renal replacement therapies in time, the cause of disease of CKD mainly contains primary glomerulonephritis, hypertensive renal arteriolar sclerosis, diabetic nephropathy, secondary glomerulonephritis, interstitial disease of renal tubule (chronic pyelonephritis, Chronic Uric-acid Nephropathy, obstructive nephropathy, Drug ephrosis etc.), ischemic nephropathy, heredity ephrosis (polycystic kindey, hereditary nephritis) etc., in developed country, diabetic nephropathy, hypertensive renal arteriolar sclerosis has become the main cause of CKD, in China, after these two kinds of diseases still occupy primary glomerulonephritis in the various cause of disease, but in recent years also have and obviously increase trend, according to the relevent statistics, the illness rate of U.S. adults (sum about 200,000,000) CKD is up to 11.3%, according to China's partial report, the susceptible factor that the illness rate of CKD is about 10%, CKD mainly contains: the age (as old age), CKD family history (comprising heredity and nongenetic ephrosis), diabetes, hypertension, obesity-metabolic syndrome, high-protein diet, hyperlipemia, hyperuricemia, autoimmune disease, urinary infection or general infection, hepatitis viruse (as B-mode or HCV) infects, stone in urinary system, urethremphraxis, urinary system or general tumour, application nephrotoxic drugs history, cardiovascular disease, anaemia, smoking, low birth weight etc., other hazards have environmental pollution, economic level is low, medical insurance level is low, level of education is low, and " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science, the traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet, allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery,
For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard traditional Chinese medicine food clear stipulaties: 2.1.1 medical science formula food: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 certain medical formula food: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition;
Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively.
Contacting of intestinal microecology system and ephrosis: study and show, accept in the ight soil of the End-stage Renal Disease Patients of dialysis, comprise enterobacteriaceae, Halomonas section, 190 sort operation unit (OTU) that the Sequence clusterings such as Moraxella section become obviously are different from Healthy People, there is the infringement of gut barrier 26S Proteasome Structure and Function in End-stage Renal Disease Patients, gut flora can be shifted by flora, inflammation and immune response etc. affect the systemic inflammatory response of this type of patient, and some metabolites also may be relevant to gut flora for the toxicity damage of kidney, there is research display, in the rat model accepting melamine process, after antibiotic suppresses gut flora activity, melamine excretion is accelerated, the toxic reaction of its induction weakens, further in vitro study shows, melamine directly can be changed into cyanuric acid by Klebsiella, accept the rat display that Klebsiella is transplanted, the renal toxicity of melamine induction increases the weight of, and in kidney, find that cyanuric acid content increases, this research is pointed out, gut flora may mediate the renal toxicity that melamine causes.
For ephrosis, though direct probiotic oral has certain effect, but due to probio cannot field planting in enteron aisle, and stop, occupy-place is little, easily run off, withdraw rear harmful bacteria and easily recur, associated patient needs long-term taking, and treatment cycle is long, and after often using, recurrence rate is very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts " Chinese medicine of the integration of drinking and medicinal herbs " compound seeking to improve probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can play field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. of raising probiotic cell, based on above-mentioned key element, suitable food materials screen from tens of kinds " Chinese medicines of integration of drinking and medicinal herbs " in this seminar, Late Cambrian interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and inulin and stachyose, yeast, after Glu etc., very strong field planting effect is had to external source probio, prescription for probio in enteral microecological formulation is selected to provide experimental basis,
Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort, B B-complex and mineral matter, composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with hepatopath, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of more than ten kinds medicine-food two-purposes, multiple probio, prebiotics is primary raw material, with small peptide, amino acid, carbohydrate, there is the grease of health care, B B-complex, the medical science formula food that composite mineral matter auxiliary material is made, certain medical formula food or similar products.
goal of the invention
The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by multiple probio and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, there is the grease of health care, B B-complex, composite mineral matter is auxiliary material, nephrotic institute essential nutrients can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the medical science formula food that the acceptable applicable nephrotic of people eats, certain medical formula food or non-medical formula food.
Summary of the invention
This R&D team is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with the constitutive character of nephrotic, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt Chinese medical extract elite and the new resource food of one or more medicine-food two-purposes, multiple probio, small peptide, prebiotics is primary raw material, with amino acid, carbohydrate, there is the grease of health care, B B-complex, composite mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets nephrotic, also has tonifying kidney and strengthening yang, benefit essence is enriched blood, nourishing liver and kidney, strengthening the muscles and bones, controlling nocturnal emission with astringent drugs contracting is urinated and is prevented and treated the medical science formula food of ephrosis, certain medical formula food or non-medical formula food (compound prescription be combined into),
The main component of the present invention's formula is:
1. Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of nephrotic, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to prevent and treat ephrosis, and choose following several large class medicine and carry out compatibility; Wherein:
The stem of noble dendrobium, Qing Dynasty's " property of medicine opinion " says: the long-pending essence of dendrobium candidum energy kidney tonifying, nourishing stomach-YIN, benefit strength, containing abundant polysaccharose substance, there is the effect strengthening immunologic function, Cordyceps sinensis can alleviate the renal lesions of chronic disease, improve renal function, alleviate the infringement of toxicant to kidney, Cordyceps militaris, the traditional Chinese medical science is thought, Chinese caterpillar fungus enters lung kidney two warp, can tonifying lung cloudy, again can kidney-replenishing, cure mainly and suffer from a deficiency of the kidney, impotence and seminal emission, soreness of waist and knee joint, weak after being ill, chronic cough is weak, phthisical cough phlegm blood, spontaneous sweating etc., that unique one can balance simultaneously, regulate the Chinese medicine of negative and positive, raspberry, sweetly put down into kidney, play sun and control impotence, controlling nocturnal emission with astringent drugs is taken the photograph excessive, strong kidney and without scorching partially, controlling nocturnal emission with astringent drugs and evil puckery undoubtedly, the product of gold and jade also, agate coffee has antifatigue, improve sperm quality, regain one's strength of body, improve impotence and premature ejaculation, improving water flood, anti-climacteric, active fertility, strengthen the effects such as memory, the useful essence of sealwort is enriched blood, strong bone establishing-Yang, the effect of anti-ageing life-prolonging, body is trembled with fear, the personages such as lumbago due to the kidney deficiency are quite effective in cure, the sweet property of fruit of Chinese wolfberry taste is put down, return liver, kidney channel.It has nourishing liver and kidney, benefit intensive culture blood, improving eyesight disappears screen, the effect moistened the lung and relieve the cough, pilose antler has stronger antifatigue effect, tolerance to cold can be strengthened, accelerated wound healing and stimulation adrenal cortex function, therefore pilose antler is traditional tonic, for strong, kidney tonifying, Yiyang, leek seed is used for liver kidney and lacks, impotence caused by decline of kidney-YANG, soreness and weakness of waist and knees is painful, testiset penis phocae has warm kidney and enhancing body, benefit essence mends effect of marrow, barrenwort acrid-sweet flavor, temperature, there is tonifying kidney and strengthening yang, the effect of dispelling rheumatism, Psoralea corylifolia has tonifying kidney and strengthening yang, effect of controlling nocturnal emission with astringent drugs contracting urine, bark of eucommia taste is sweet, warm in nature.Return liver, kidney, stomach warp, effect tonify the liver and kidney, strengthen muscles and bones, coordinating Chong and Conception Vessels, solid through antiabortive,
Medicinal and edible Chinese medicine extract of the present invention refer to the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, raspberry, agate coffee, sealwort, pilose antler, leek seed, testiset penis phocae, barrenwort, Psoralea corylifolia, the bark of eucommia, dark plum, Chinese cassia tree, Gorgon fruit, mulberries, lotus seeds, nutmeg, walnut kernel, the seed of Chinese dodder, the fleece-flower root, ginseng, sophora flower, gingko, fructus alpiniae oxyphyllae, black fungus, mulberry leaf, rape pollen, donkey-hide gelatin, chestnut,
ah's Say fruit, eucommia Bark male flower, Guangdong Cordyceps militaris, Saussurea involucrata culture, newborn mineral saltone wherein, several or whole, adopt biological enzymolysis or prehydrolysis SBE to extract and microencapsulation, spray-dried and cryodesiccated extract all mixes;
2. many kinds of probios: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by urease-producing in suppression enteron aisle and the growth of producing ammonium bacteria, carrys out the generation of disease preventing and treating;
Multiple probio of the present invention all adopts the probio after microencapsulation, and the probio described in it is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici are wherein a kind of, several or all mix;
Bifidobacterium above a refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);
Lactobacillus above b refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii subspecies, lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri;
3. small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,
Small peptide of the present invention refers to that maize oligopeptide, wheat oligopeptide, marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix;
4. prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, stimulate enterocinesia to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of disease;
A. very strong field planting effect prebiotics is had to external source probio: the extract of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin;
B. common prebiotics: oligoisomaltose, FOS, trehalose, soyabean oligosaccharides, xylo-oligosaccharide, cotton seed compound sugar, stachyose, yeast;
Prebiotics of the present invention is: the extract of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, stachyose, yeast, oligoisomaltose, trehalose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;
5. carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,
Carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, carbohydrate, has the grease of health care, starch, glycogen one wherein, several or all mix;
6. there is the grease of health care to refer to there is health-care effect to the person, and finished product energy can be increased, make the energy contained by the every 100g of finished product of the present invention should be not less than 295kJ (70kcal); As the street cleaner that fish oil is human vas, can also prevention of arterial sclerosis, apoplexy and heart disease.Fish oil is the diseases such as hypertension, coronary heart disease, headstroke, diabetes, rheumatic arthritis, cancer; Linseed oil has fat-reducing, reduces cholesterol, improves the effects such as renal function; Peony seed oil has reducing blood lipid and hypotensive, strengthens autoimmunity, prevention diabetes, effect of anti-curing cancers; Samara oil prevents and treats hypertension, high fat of blood, effect of the illnesss such as vascular sclerosis;
Of the present invention have the grease of health care to refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix,
7. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;
Amino acid of the present invention refers to Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix;
8. vitamin and mineral matter: vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;
The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;
The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;
In the present invention, the addition of vitamin and minerals performs with reference to " special medicine purposes formula food general rule ", now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, make product prevent and treat ephrosis effect and significantly improve compared with the like product of market;
9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add black sesame powder etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out in clean dried environment;
The characteristic of this medical science formula food and the following aspects is mainly manifested in the effect of body:
1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of nephrotic, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility;
2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, the grease having health care, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect;
3. have effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb quick, complete, nephrotic's desired nutritional can be supplemented rapidly, not increase liver kidney burden;
4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, also have tonifying kidney and strengthening yang, beneficial essence is enriched blood, nourishing liver and kidney, strengthening the muscles and bones, controlling nocturnal emission with astringent drugs contracting urine and prevent and treat effect of ephrosis;
5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced,
6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, can effectively improve nephrotic's negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa;
7. this prescription have employed this team by the achievement to probio key technology research of field planting mechanism in enteron aisle over nearly 3 year, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio;
8. prebiotics contained in the present invention's formula, by promoting the growth and breeding of probio in intestines, suppress the growth of spoilage organisms, form one protective barrier at intestinal mucosal surface simultaneously, the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted, reduce the absorption of intestinal toxic material, intestines peristalsis can also be promoted, accelerate the discharge of residuals in intestines, constipation can be prevented, and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivator such as small peptide and active polysaccharide has synergy;
9. in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) that conveys hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce;
10. in the present invention's formula, the contained grease of health care that has not only has health-care effect to the person, and provides the energy needed for normal life for human body, makes the energy contained by the every 100g of finished product of the present invention should be not less than 295kJ (70kcal);
Amino acid contained in 11. the present invention's formulas, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development;
12. formula foods of the present invention containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for nephrotic, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element;
Not fatty and cholesterol in 13. the present invention's formulas, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.
Detailed description of the invention
Below by following case study on implementation, the invention will be further described, and it will contribute to understanding the present invention.
Case study on implementation one
Realizing the full nutritional formulas of the object of the invention ephrosis is constitutive character in conjunction with nephrotic, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with prebiotics, carbohydrate, amino acid, the medical science formula food that has the grease of health care, multivitamin, several mineral materials to make for auxiliary material;
Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: stem of noble dendrobium 12g, Cordyceps sinensis (aweto mycelium) 12g, Cordyceps militaris 11g, raspberry 11g, agate coffee 9g, sealwort 9g, pilose antler 8g, leek seed 8g, testiset penis phocae 7g, barrenwort 7g, Psoralea corylifolia 7g, bark of eucommia 7g, dark plum 7g, Chinese cassia tree 7g, Gorgon fruit 7g, mulberries 6g, lotus seeds 6g, nutmeg 6g, walnut kernel 6g, seed of Chinese dodder 6g, fleece-flower root 6g, ginseng 5g, sophora flower 5g, gingko 5g, fructus alpiniae oxyphyllae 5g, black fungus 5g, mulberry leaf 5g, rape pollen 4g, donkey-hide gelatin 4g, chestnut 4g,
ah's Say fruit4g
, eucommia Bark male flower3g
, Guangdong Cordyceps militaris3g
, Saussurea involucrata culture2g
, newborn mineral salt1g
,multiple probio 300g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
During making first will be the stem of noble dendrobium, raspberry, agate coffee, sealwort, pilose antler, leek seed, testiset penis phocae, barrenwort, Psoralea corylifolia, the bark of eucommia, dark plum, Chinese cassia tree, Gorgon fruit, mulberries, lotus seeds, nutmeg, the seed of Chinese dodder, the fleece-flower root, ginseng, sophora flower, gingko, fructus alpiniae oxyphyllae, black fungus, mulberry leaf,
ah's Say fruit, eucommia Bark male flowercycloheptaamylose is added after immersion, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, then add biological enzymolysis extract Cordyceps sinensis (aweto mycelium), Cordyceps militaris, lotus nut starch, walnut kernel, rape pollen, donkey-hide gelatin, chest nut powder,
guangdong Cordyceps militaris, Saussurea involucrata culture, newborn mineral salt,small peptide, prebiotics, amino acid, carbohydrate, have the grease of health care, multivitamin and mineral matter to be pulverized and mixed together after carry out pasteurization 1 hour, then the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus mix solid beverage, the granule of making powdery is added, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require;
Manufacture craft of the present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat ephrosis significantly improves compared with the like product of market.
Case study on implementation two
Above-mentioned ephrosis medical science formula food also comprises following component by weight, the extract of medicine-food two-purpose: Cordyceps militaris 11g, raspberry 11g, agate coffee 9g, sealwort 9g, pilose antler 8g, leek seed 8g, testiset penis phocae 7g, barrenwort 7g, Psoralea corylifolia 7g, bark of eucommia 7g, dark plum 7g, Chinese cassia tree 7g, Gorgon fruit 7g, mulberries 6g, lotus seeds 6g, nutmeg 6g, walnut kernel 6g, seed of Chinese dodder 6g, fleece-flower root 6g, ginseng 5g, sophora flower 5g, gingko 5g, fructus alpiniae oxyphyllae 5g, black fungus 5g, mulberry leaf 5g, rape pollen 4g, donkey-hide gelatin 4g, chestnut 4g,
ah's Say fruit4g
, eucommia Bark male flower3g
, Guangdong Cordyceps militaris3g
, Saussurea involucrata culture2g
, newborn mineral salt1g
,, prebiotics 350g, probio 300g, small peptide 150g, several amino acids 100g, carbohydrate 100g, the grease 100g having health care, carbohydrate, the grease having health care, 50g, vitamin and mineral matter 25g.
Case study on implementation three
Above-mentioned ephrosis medical science formula food also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Case study on implementation four
The certain medical formula food of above-mentioned ephrosis also comprises following component by weight: prebiotics 700g, small peptide 500g, carbohydrate 300g, multiple probio 300g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Case study on implementation five
Above-mentioned ephrosis medical science formula food also comprises following component by weight: prebiotics 500g, small peptide 350g, carbohydrate 300g, multiple probio 250g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Case study on implementation six
Above-mentioned ephrosis medical science formula food also comprises following component by weight: small peptide 350g, prebiotics 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Claims (10)
1. ephrosis medical science formula food, it is characterized in that the constitutive character in conjunction with nephrotic, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with prebiotics, carbohydrate, amino acid, the medical science formula food that has the grease of health care, multivitamin, several mineral materials to make for auxiliary material;
Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: stem of noble dendrobium 12g, Cordyceps sinensis (aweto mycelium) 12g, Cordyceps militaris 11g, raspberry 11g, agate coffee 9g, sealwort 9g, pilose antler 8g, leek seed 8g, testiset penis phocae 7g, barrenwort 7g, Psoralea corylifolia 7g, bark of eucommia 7g, dark plum 7g, Chinese cassia tree 7g, Gorgon fruit 7g, mulberries 6g, lotus seeds 6g, nutmeg 6g, walnut kernel 6g, seed of Chinese dodder 6g, fleece-flower root 6g, ginseng 5g, sophora flower 5g, gingko 5g, fructus alpiniae oxyphyllae 5g, black fungus 5g, mulberry leaf 5g, rape pollen 4g, donkey-hide gelatin 4g, chestnut 4g,
ah's Say fruit4g
, eucommia Bark male flower3g
, Guangdong Cordyceps militaris3g
, Saussurea involucrata culture2g
, newborn mineral salt1g
,multiple probio 300g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
During making first will be the stem of noble dendrobium, raspberry, agate coffee, sealwort, pilose antler, leek seed, testiset penis phocae, barrenwort, Psoralea corylifolia, the bark of eucommia, dark plum, Chinese cassia tree, Gorgon fruit, mulberries, lotus seeds, nutmeg, the seed of Chinese dodder, the fleece-flower root, ginseng, sophora flower, gingko, fructus alpiniae oxyphyllae, black fungus, mulberry leaf,
ah's Say fruit, eucommia Bark male flowercycloheptaamylose is added after immersion, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, then add biological enzymolysis extract Cordyceps sinensis (aweto mycelium), Cordyceps militaris, lotus nut starch, walnut kernel, rape pollen, donkey-hide gelatin, chest nut powder,
guangdong Cordyceps militaris, Saussurea involucrata culture, newborn mineral salt,small peptide, prebiotics, amino acid, carbohydrate, have the grease of health care, multivitamin and mineral matter to be pulverized and mixed together after carry out pasteurization 1 hour, then the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus mix solid beverage, the granule of making powdery is added, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require;
Manufacture craft of the present invention is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat ephrosis significantly improves compared with the like product of market.
2. ephrosis medical science formula food according to claim 1, is characterized in that described medicine-food two-purpose Chinese herbal medicine extract and new resource food are: the stem of noble dendrobium, raspberry, agate coffee, sealwort, pilose antler, leek seed, testiset penis phocae, barrenwort, Psoralea corylifolia, the bark of eucommia, dark plum, Chinese cassia tree, Gorgon fruit, mulberries, lotus seeds, nutmeg, the seed of Chinese dodder, the fleece-flower root, ginseng, sophora flower, gingko, fructus alpiniae oxyphyllae, black fungus, mulberry leaf,
ah's Say fruit, eucommia Bark male flower, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, lotus nut starch, walnut kernel, rape pollen, donkey-hide gelatin, chest nut powder,
guangdong Cordyceps militaris, Saussurea involucrata culture, newborn mineral salt are whereinone, several or all mix.
3. ephrosis medical science formula food according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.
4. ephrosis medical science formula food according to claim 1, also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295 kJ (70 kcal).
5. ephrosis medical science formula food according to claim 1, is characterized in that described probio is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici, wherein a kind of, several or all mix;
Bifidobacterium above refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);
Lactobacillus above refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri.
6. ephrosis medical science formula food according to claim 1, it is characterized in that described prebiotics is: the extraction mixture of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, trehalose, stachyose, yeast, oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix.
7. ephrosis medical science formula food according to claim 1, is characterized in that described amino acid is: Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.
8. the medical science formula food of ephrosis according to claim 1, is characterized in that described carbohydrate is that carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.
9. ephrosis medical science formula food according to claim 1, it is characterized in that the described grease of health care that has is: refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix.
10. ephrosis medical science formula food according to claim 1, is characterized in that described small peptide is: marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510171573.5A CN104839678A (en) | 2015-04-13 | 2015-04-13 | Medical formula food for people with nephrosis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510171573.5A CN104839678A (en) | 2015-04-13 | 2015-04-13 | Medical formula food for people with nephrosis |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106108028A (en) * | 2016-07-02 | 2016-11-16 | 威海御膳坊生物科技有限公司 | A kind of patients of chronic renal failure special medicine purposes formula food |
| CN106421371A (en) * | 2016-11-27 | 2017-02-22 | 山东华胶饮品有限公司 | Formula of cordyceps militaris rhizoma polygonati tablet and preparation method thereof |
| CN110269897A (en) * | 2019-07-12 | 2019-09-24 | 成都中医药大学 | Composition and application thereof that is a kind of antifatigue and improving sleep |
| CN110584132A (en) * | 2019-09-04 | 2019-12-20 | 得利斯集团有限公司 | Special medical nutritional formula food for kidney diseases and preparation method thereof |
| EP3644753A4 (en) * | 2017-06-26 | 2021-02-24 | Kibow Biotech, Inc. | Methods for maintaining and improving kidney function in patients with kidney disease and on standard of care therapy |
-
2015
- 2015-04-13 CN CN201510171573.5A patent/CN104839678A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106108028A (en) * | 2016-07-02 | 2016-11-16 | 威海御膳坊生物科技有限公司 | A kind of patients of chronic renal failure special medicine purposes formula food |
| CN106421371A (en) * | 2016-11-27 | 2017-02-22 | 山东华胶饮品有限公司 | Formula of cordyceps militaris rhizoma polygonati tablet and preparation method thereof |
| EP3644753A4 (en) * | 2017-06-26 | 2021-02-24 | Kibow Biotech, Inc. | Methods for maintaining and improving kidney function in patients with kidney disease and on standard of care therapy |
| CN110269897A (en) * | 2019-07-12 | 2019-09-24 | 成都中医药大学 | Composition and application thereof that is a kind of antifatigue and improving sleep |
| CN110584132A (en) * | 2019-09-04 | 2019-12-20 | 得利斯集团有限公司 | Special medical nutritional formula food for kidney diseases and preparation method thereof |
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Application publication date: 20150819 |