CN105029407A - Medical formula food for inflammatory bowel disease - Google Patents
Medical formula food for inflammatory bowel disease Download PDFInfo
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- CN105029407A CN105029407A CN201510173170.4A CN201510173170A CN105029407A CN 105029407 A CN105029407 A CN 105029407A CN 201510173170 A CN201510173170 A CN 201510173170A CN 105029407 A CN105029407 A CN 105029407A
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- lactobacillus
- inflammatory bowel
- food
- oil
- bowel disease
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Abstract
The invention belongs to the technical field of affinal-drug-and-diet formulas and new-resource foods, and particularly provides a medical formula food for patients in inflammatory bowel disease. The formula is designed according to the requirement in "National Food Safety Standard General Rules on Formula Food for Special Medical Use". With consideration of the body characters of patients in the inflammatory bowel disease, various "affinal-drug-and-diet" traditional Chinese medicines are combined reasonably according to traditional Chinese medicine essential principles, and a plurality of affinal-drug-and-diet traditional Chinese medicine extract essences which are extracted through a pre-hydrolysis SBE technology, various micro-capsulated probiotics, oligopeptides extracted through bio-enzymolysis, prebiotics, amino acids, carbohydrates, grease having health-caring functions, various vitamins and minerals are all mixed together and are subjected to other processes to obtain the medical formula food. The medical formula food can be used for satisfying nutrition requirement of the patients in the inflammatory bowel disease as a single nutritional source, and also has the effects of moving qi and promoting digestion, fortifying spleen and promoting appetite, quieting spirit and improving intelligence, treating food accumulation and poor digestion, distention and pain in gastral cavity and abdomen, deficiency in spleen and poor appetite, and enhancing body immunity.
Description
Technical field
The invention belongs to integration of drinking and medicinal herbs class formula and new resource food technical field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds with small peptide, prebiotics, amino acid, carbohydrate, the medical science formula food of control inflammatory bowel disease having the grease of health care, B B-complex, composite mineral matter to make for auxiliary material, certain medical formula food or non-medical formula food.
Background technology
Inflammatory bowel disease, be called for short IBD, it is a kind of special chronic gut inflammation disease, mainly comprise Crohn disease (CD) and ulcerative colitis (UC), over nearly 30 years, China's IBD incidence of disease has constantly soaring trend, report according to domestic literature, the case load of nearly 5 years is 8 times of the same period nineties in last century, IBD becomes the common disease of Gastroenterology dept. of China gradually, " chronic enteritis " in a lot of common people's mouth is exactly probably IBD, IBD Intestinal Mucosal Injury in Patients Undergoing can not normal absorption feed carbohydrate, protein, fat, vitamin and various trace elements, add that intestinal inflammatory or the medicine taken may cause to be off one's feed, therefore IBD is often along with malnutrition in various degree, even affect child to grow normally, nutritional support has important effect to IBD remission and Promotive union, therefore self good nutritional status is kept to be treatment IBD part and parcel, there is not special special diet in IBD, the tolerant food of different people has different, therefore the diet principle that IBD is total ensures that oneself diet balance avoids some to make the food of disease progression simultaneously, a lot of expert thinks, inflammatory bowel disease is not fearful, as long as form healthy lifestyles, ensure feed, have a rest, medicine law, the regular follow-up monitoring state of an illness, inflammatory bowel disease be can control carbohydrate, protein, fat, vitamin and various trace elements, the cause of disease of IBD and pathogenesis are not yet completely clear and definite, known Intestinal Mucosal Immunization system exception reacts the inflammatory reaction caused and plays an important role in IBD morbidity, think that this is caused by multifactor interaction, mainly comprise environment, heredity, infection and immunity factor, one, environmental factor in recent decades, the incidence of disease of IBD (UC and CD) continues to increase, first this phenomenon appears at the highly developed North America of social economy, Northern Europe, then be West Europe, southern Europe, be only Japan recently, South America, this phenomenon reflects the delicate but important change of environmental factor, as diet, smoking or be exposed to other factors be still not clear, two, inherent cause, another important phenomenon of IBD morbidity is that IBD patient's first degree relative incidence of disease is significantly higher than general population, and spouse's incidence of disease of patient does not increase, discovery is studied on a large scale by one, Sweden, CD incidence of disease monozygotic twins is significantly higher than the two born of the same parents of two ovum, existing in a large number about the report of IBD related gene, early stage research mainly concentrates on HLA allele and Cytokine Gene Polymorphisms, but the result of report differs, mainly may with not agnate, crowd's genetic background is relevant, in recent years clone is positioned to genome, find in the study on large sample of IBD family, the susceptible point of IBD is positioned at the 3rd, 7, 12, on No. 16 chromosomes, relevant research is still in deeply carrying out, think, IBD is not only polygenic disease, and be genetic heterogeneity disease (different people is caused by different genes), patient falls ill due to inheritance susceptible under certain environmental factor effect, three, the effect of infective agent microorganism in IBD morbidity comes into one's own always, but not yet find a certain specific microorganism cause of disease and IBD to have constant relationship so far, have research think mycobacterium paratuberculosis and measles virus relevant with CD, but evidence still lacks persuasion.In recent years just day by day come into one's own about the another kind of viewpoint that microorganism is pathogenic, this viewpoint think IBD (particularly CD) be for self normal bowel flora abnormal immune reaction cause, the evidence of two aspects is had to support this viewpoint, on the one hand from the animal model of IBD, by transgenosis or knock out the IBD animal model that genetic method causes immune deficiency, intestinal inflammatory can not be there is under enteron aisle gnotobasis, but as again recovered intestinal tract normal flora plexi state, then there is intestinal inflammatory
" integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science; The traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery;
For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard traditional Chinese medicine food clear stipulaties: 2.1.1 medical science formula food: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 certain medical formula food: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition;
Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively;
Contacting of intestinal microecology system and inflammatory bowel disease: in human inflammatory bowel disease, the bacterium colony of field planting is one of principal element caused inflammation, Chron patient, its small intestine T lymphocyte is extremely sensitive to bacterial antigens, the local tolerance mechanism of this patient disappears, in addition, the IgG antibody amount of Crohn disease and patients of ulcerative colitis intestinal secretion increases, in order to resist the symbiotic bacteria of wide spectrum, the inflammatory immune response mediated by IgG has damage intestinal mucosa, this is mainly because they have activated the cascade reaction of complementary reaction and a series of inflammatory mediator, and, in the patient of inflammatory bowel, the bacterial number adhering to epithelial surface is more than Healthy People.Bacterium colony composition, to the unrestricted activation of intestinal tract immune system, the Pathological Physiology of inflammatory bowel disease may play vital effect.Some cd patients (17%-25%) regulate host to have sudden change to the NOD2/CARD15 gene that bacterial immune is replied; As can be seen here, inflammatory bowel disease and intestinal microecology is unbalance close contacting.
Though direct probiotic oral has certain effect, but due to probio cannot field planting in enteron aisle, and stop, occupy-place is little, easily run off, withdraw rear harmful bacteria and easily recur, associated patient needs long-term taking, and treatment cycle is long, often uses afterwards that recurrence rate is very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts " Chinese medicine of the integration of drinking and medicinal herbs " compound seeking to improve probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can play field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. of raising probiotic cell, based on above-mentioned key element, suitable food materials screen from tens of kinds " Chinese medicines of integration of drinking and medicinal herbs " in this seminar, Late Cambrian interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and inulin and stachyose, yeast, after Glu etc., very strong field planting effect is had to external source probio, prescription for probio in enteral microecological formulation is selected to provide experimental basis,
Favourable is in the market primary raw material in order to eat source property small peptide, add the stem of noble dendrobium of medicine-food two-purpose, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, the extract of radish seed etc., B B-complex and mineral matter, composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with patients with inflammatory bowel, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of more than ten kinds medicine-food two-purposes, multiple probio, prebiotics is primary raw material, with small peptide, amino acid, carbohydrate, there is the grease of health care, B B-complex, the medical science formula food that composite mineral matter auxiliary material is made, certain medical formula food or similar products.
goal of the invention
The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by multiple anti-diabetic probio and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, there is the grease of health care, B B-complex, composite mineral matter is auxiliary material, patients with inflammatory bowel institute essential nutrients can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the medical science formula food that the acceptable applicable patients with inflammatory bowel of people is edible, certain medical formula food or non-medical formula food.
summary of the invention:
This R&D team is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with the constitutive character of patients with inflammatory bowel, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt Chinese medical extract elite and the new resource food of one or more medicine-food two-purposes, multiple probio, small peptide, prebiotics is primary raw material, with amino acid, carbohydrate, there is the grease of health care, B B-complex, composite mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets patients with inflammatory bowel, also has reinforcing stomach reg fluid, long-pendingization that disappear is stagnant, replenishing the vital essence and removing heat, promote qi circulation digestion promoting, and the medical science formula food of control inflammatory bowel disease, certain medical formula food or non-medical formula food (compound prescription be combined into),
The main component of the present invention's formula is:
1. Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of diabetic, utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function control inflammatory bowel disease, and choose following several large class medicine and carry out compatibility; Wherein:
Stem of noble dendrobium taste is sweet, cold nature, energy replenishing the vital essence and removing heat, reinforcing stomach reg fluid, lipolytic enzyme contained by hawthorn can promote the digestion of fat food and promote gastric secretion and increase the functions such as stomach endoenzyme element, it is stagnant that hawthorn has long-pendingization that disappear, convergence is dysentery only, the effect such as activate blood circulation and disperse blood clots, cure mainly eating accumulation, chest diaphragm spleen is full, the diseases such as hernia blood stasis amenorrhoea, containing the drug ingedient such as mountain terpene and flavonoids in hawthorn, there is significant hemangiectasis and hypotensive effect, have and strengthen cardiac muscle, arrhythmia, the function of adjusting blood lipid and cholesterol level, the membrane of a chicken's gizzard is sweet flat, be slightly cold, nontoxic, return spleen, stomach, kidney, urinary bladder channel, can food digesting stomach fortifying, arresting seminal emission, cure mainly disappear stagnant, strengthening the spleen and stomach.Control dyspepsia turgor, vomiting gastric disorder causing nausea, the flavone compound contained in sea-buckthorn has very high medical value, cholesterol can be reduced, allevating angina pectoris shows effect, and also has the effect of anti-inflammatory, containing a kind of ferment in pawpaw, energy digesting protein, be conducive to human body and effect that absorption and digestion has reinforcing spleen to promote digestion is carried out to food, containing a large amount of abundant carrotene, protein, calcium salt, protease, lemon enzyme etc., inflammation can be prevented and treated, radish seed helps digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, constipation, stagnant rush down dysentery, phlegm stops up and breathes with cough, banksia rose taste is pungent, bitter, warm in nature; Return spleen, stomach, lung channel, promoting qi circulation and relieving pain; Lead stagnant in tune.Main born of the same parents coerce turgor foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery, rascal has soothing the liver relieving stagnant Qi, the effect of dissipating bind dissolving phlegm, can control chest side of body gastral cavity pain, hernia, dyspepsia, the bighead atractylodes rhizome can tonifying spleen, beneficial stomach, eliminating dampness, and in, antiabortive, for controlling deficient QI of the spleen and stomach, do not feel like eating, Hericium erinaceus can promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, to calm the nerves intelligence development, do not disappear for dyspepsia, abdominal distention, insufficiency of the spleen food is few, insomnia and dreamful sleep
Medicinal and edible Chinese medicine extract of the present invention refer to the stem of noble dendrobium, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, radish seed, the banksia rose, rascal, the bighead atractylodes rhizome, Cordyceps sinensis, Cordyceps militaris, ginger, Hericium erinaceus, fructus amomi, fructus alpiniae oxyphyllae, nutmeg, blunt top spirulina, pollen pini, Fructus Hordei Germinatus, cape jasmine, cloves, almond, Buddha's hand, Radix Glycyrrhizae, dark plum, almond, raisins, rice germ, natto, the root of kudzu vine,
strange sub-seed, the luxuriant isapgol husk of circle, Qingqian Willow leaf, Tea Flower, Euglena, sky shellfish, Guangdong Cordyceps militaris, Saussurea involucrata culture, newborn mineral saltone wherein, several or whole, adopt biological enzymolysis or prehydrolysis SBE to extract and microencapsulation, spray-dried and cryodesiccated extract all mixes;
2. many kinds of probios: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, research application enteron aisle is had not absorb rifamycin antibiotic former times bright (rifaximin), by suppressing the growth of urease-producing and product ammonium bacteria in enteron aisle, prevent and treat the generation of inflammatory bowel disease;
Multiple probio of the present invention all adopts the probio after microencapsulation, and the probio described in it is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici are wherein a kind of, several or all mix;
Bifidobacterium above a refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);
Lactobacillus above b refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii subspecies, lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri;
3. small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,
Small peptide of the present invention refers to that maize oligopeptide, wheat oligopeptide, marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix;
4. prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, stimulate enterocinesia to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of inflammatory bowel disease;
Prebiotics of the present invention is 2 classes
A. have very strong field planting effect prebiotics to external source probio: Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin extract;
B. common prebiotics: oligoisomaltose, FOS, trehalose, soyabean oligosaccharides, xylo-oligosaccharide, cotton seed compound sugar, stachyose, yeast;
Prebiotics of the present invention is: the extract of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, stachyose, yeast, oligoisomaltose, trehalose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;
5. carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,
Carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, carbohydrate, has the grease of health care, starch, glycogen one wherein, several or all mix;
6. there is the grease of health care to refer to there is health-care effect to the person, and finished product energy can be increased, make the energy contained by the every 100g of finished product of the present invention should be not less than 295kJ (70kcal); As the street cleaner that fish oil is human vas, can also prevention of arterial sclerosis, apoplexy and heart disease.Fish oil is the diseases such as hypertension, coronary heart disease, headstroke, diabetes, rheumatic arthritis, cancer; Linseed oil has fat-reducing, reduces cholesterol, improves the effects such as renal function; Peony seed oil has reducing blood lipid and hypotensive, strengthens autoimmunity, prevention diabetes, effect of anti-curing cancers; Samara oil prevents and treats hypertension, high fat of blood, effect of the illnesss such as vascular sclerosis;
Of the present invention have the grease of health care to refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix,
7. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;
Amino acid of the present invention refers to Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix;
8. vitamin and mineral matter: vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;
The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;
The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;
In the present invention, the addition of vitamin and minerals performs with reference to " special medicine purposes formula food general rule ", now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, make product prevent and treat inflammatory bowel disease effect and significantly improve compared with the like product of market;
9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add black sesame powder etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out in clean dried environment;
The characteristic of this formula medical science formula food and the following aspects is mainly manifested in the effect of body:
1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of patients with inflammatory bowel, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility;
2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, the grease having health care, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect;
3. there is effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb quick, complete, patients with inflammatory bowel desired nutritional can be supplemented rapidly, not increase liver kidney burden;
4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, also have that reinforcing stomach reg fluid, long-pendingization that disappear are stagnant, replenishing the vital essence and removing heat, promote qi circulation digestion promoting and prevent and treat effect of inflammatory bowel disease;
5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced,
6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, can effectively improve patients with inflammatory bowel negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa;
7. this prescription have employed this team by the achievement to probio key technology research of field planting mechanism in enteron aisle over nearly 3 year, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio;
8. prebiotics contained in the present invention's formula, by promoting the growth and breeding of probio in intestines, suppress the growth of spoilage organisms, form one protective barrier at intestinal mucosal surface simultaneously, the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted, reduce the absorption of intestinal toxic material, intestines peristalsis can also be promoted, accelerate the discharge of residuals in intestines, constipation can be prevented, and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivator such as small peptide and active polysaccharide has synergy;
9. in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) that conveys hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce;
10. in the present invention's formula, the contained grease of health care that has not only has health-care effect to the person, and provides the energy needed for normal life for human body, makes the energy contained by the every 100g of finished product of the present invention should be not less than 295kJ (70kcal);
Amino acid contained in 11. the present invention's formulas, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development;
12. formula foods of the present invention containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for patients with inflammatory bowel, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element;
Not fatty and cholesterol in 13. the present invention's formulas, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.
Detailed description of the invention
Below by following case study on implementation, the invention will be further described, and it will contribute to understanding the present invention.
Case study on implementation one
Realizing the full nutritional formulas of the object of the invention inflammatory bowel disease is constitutive character in conjunction with patients with inflammatory bowel, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with prebiotics, carbohydrate, amino acid, the medical science formula food that has the grease of health care, multivitamin, several mineral materials to make for auxiliary material;
Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: stem of noble dendrobium 12g, hawthorn 12g, the membrane of a chicken's gizzard 11g, sea-buckthorn 11g, pawpaw 10g, radish seed 10g, banksia rose 8g, rascal 8g, bighead atractylodes rhizome 8g, Cordyceps sinensis 7g, Cordyceps militaris 7g, ginger 6g, Hericium erinaceus 6g, fructus amomi 6g, fructus alpiniae oxyphyllae 6g, nutmeg 5g, blunt top spirulina 5g, pollen pini 5g, Fructus Hordei Germinatus 5g, cape jasmine 4g, cloves 4g, almond 4g, Buddha's hand 3g, Radix Glycyrrhizae 3g, dark plum 3g, almond 3g, raisins 3g, rice germ 3g, natto 3g, root of kudzu vine 3g,
strange sub-seed3g
, circle luxuriant isapgol husk3g
, Qingqian Willow leaf2g
, Tea Flower2g
, Euglena2g
, sky shellfish2g
, Guangdong Cordyceps militaris2g
, Saussurea involucrata culture 1g, newborn mineral salt1g
,multiple probio 300g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
During making first will be the stem of noble dendrobium, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, radish seed, the banksia rose, rascal, bighead atractylodes rhizome ginger, Hericium erinaceus, fructus amomi, fructus alpiniae oxyphyllae, nutmeg, blunt top spirulina, pollen pini, Fructus Hordei Germinatus, cape jasmine, cloves, almond, Buddha's hand, Radix Glycyrrhizae, dark plum, almond, raisins, rice germ, natto,
strange sub-seed, the luxuriant isapgol husk of circle, Qingqian Willow leaf, Tea Flower, Euglena, sky shellfishadd cycloheptaamylose after immersion, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid,
guangdong Cordyceps militaris,cordyceps sinensis, Cordyceps militaris, the root of kudzu vine,
saussurea involucrata culture, newborn mineral salt, carbohydrate, have the grease of health care, multivitamin and mineral matter to be pulverized and mixed together after carry out pasteurization 1 hour, then the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus mix solid beverage, the granule of making powdery is added, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require;
Manufacture craft of the present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat inflammatory bowel disease significantly improves compared with the like product of market.
Case study on implementation two
Above-mentioned inflammatory bowel disease medical science formula food also comprises following component by weight, the extract of medicine-food two-purpose: Cordyceps militaris 7g, ginger 6g, Hericium erinaceus 6g, fructus amomi 6g, fructus alpiniae oxyphyllae 6g, nutmeg 5g, blunt top spirulina 5g, pollen pini 5g, Fructus Hordei Germinatus 5g, cape jasmine 4g, cloves 4g, almond 4g, Buddha's hand 3g, Radix Glycyrrhizae 3g, dark plum 3g, almond 3g, raisins 3g, rice germ 3g, natto 3g, root of kudzu vine 3g,
strange sub-seed3g
, circle luxuriant isapgol husk3g
, Qingqian Willow leaf2g
, Tea Flower2g
, Euglena2g
, sky shellfish2g
, Guangdong Cordyceps militaris2g
, Saussurea involucrata culture 1g, newborn mineral salt1g
,prebiotics 350g, probio 300g, small peptide 150g, several amino acids 100g, carbohydrate 100g, the grease 100g having health care, carbohydrate, the grease having health care, 50g, vitamin and mineral matter 25g.
Case study on implementation three
Above-mentioned inflammatory bowel disease medical science formula food also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Case study on implementation four
The certain medical formula food of above-mentioned inflammatory bowel disease also comprises following component by weight: prebiotics 700g, small peptide 500g, carbohydrate 300g, multiple probio 300g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Case study on implementation five
Above-mentioned inflammatory bowel disease medical science formula food also comprises following component by weight: prebiotics 500g, small peptide 350g, carbohydrate 300g, multiple probio 250g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Case study on implementation six
Above-mentioned inflammatory bowel disease medical science formula food also comprises following component by weight: small peptide 350g, prebiotics 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
Claims (10)
1. inflammatory bowel disease medical science formula food, it is characterized in that the constitutive character in conjunction with patients with inflammatory bowel, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with prebiotics, carbohydrate, amino acid, the medical science formula food that has the grease of health care, multivitamin, several mineral materials to make for auxiliary material;
Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: stem of noble dendrobium 12g, hawthorn 12g, the membrane of a chicken's gizzard 11g, sea-buckthorn 11g, pawpaw 10g, radish seed 10g, banksia rose 8g, rascal 8g, bighead atractylodes rhizome 8g, Cordyceps sinensis 7g, Cordyceps militaris 7g, ginger 6g, Hericium erinaceus 6g, fructus amomi 6g, fructus alpiniae oxyphyllae 6g, nutmeg 5g, blunt top spirulina 5g, pollen pini 5g, Fructus Hordei Germinatus 5g, cape jasmine 4g, cloves 4g, almond 4g, Buddha's hand 3g, Radix Glycyrrhizae 3g, dark plum 3g, almond 3g, raisins 3g, rice germ 3g, natto 3g, root of kudzu vine 3g, strange sub-seed 3g, the luxuriant isapgol husk 3g of circle, Qingqian Willow leaf 2g, Tea Flower 2g, Euglena 2g, it shellfish 2g, the sub-2g of Guangdong Cordyceps militaris, Saussurea involucrata culture 1g, breast mineral salt 1g, multiple probio 300g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
First will to be the stem of noble dendrobium during making, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, radish seed, the banksia rose, rascal, bighead atractylodes rhizome ginger, Hericium erinaceus, fructus amomi, fructus alpiniae oxyphyllae, nutmeg, blunt top spirulina, pollen pini, Fructus Hordei Germinatus, cape jasmine, cloves, almond, Buddha's hand, Radix Glycyrrhizae, dark plum, almond, raisins, rice germ, natto, strange sub-seed, the luxuriant isapgol husk of circle, Qingqian Willow leaf, Tea Flower, Euglena, it shellfish soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, Guangdong Cordyceps militaris, Cordyceps sinensis, Cordyceps militaris, the root of kudzu vine, Saussurea involucrata culture, breast mineral salt, carbohydrate, there is the grease of health care, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require,
Manufacture craft of the present invention is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat inflammatory bowel disease significantly improves compared with the like product of market.
2. inflammatory bowel disease medical science formula food according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract and new resource food are: the stem of noble dendrobium, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, radish seed, the banksia rose, rascal, bighead atractylodes rhizome ginger, Hericium erinaceus, fructus amomi, fructus alpiniae oxyphyllae, nutmeg, blunt top spirulina, pollen pini, Fructus Hordei Germinatus, cape jasmine, cloves, almond, Buddha's hand, Radix Glycyrrhizae, dark plum, almond, raisins, rice germ, natto, strange sub-seed, the luxuriant isapgol husk of circle, Qingqian Willow leaf, Tea Flower, Euglena, it shellfish, Guangdong Cordyceps militaris, Cordyceps sinensis, Cordyceps militaris, the root of kudzu vine, Saussurea involucrata culture, breast mineral salt one wherein, several or all mix.
3. inflammatory bowel disease medical science formula food according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.
4. inflammatory bowel disease medical science formula food according to claim 1, also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).
5. inflammatory bowel disease medical science formula food according to claim 1, is characterized in that described probio is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici, wherein a kind of, several or all mix;
Bifidobacterium above refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);
Lactobacillus above refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri.
6. inflammatory bowel disease medical science formula food according to claim 1, it is characterized in that described prebiotics is: the extraction mixture of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, trehalose, stachyose, yeast, oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix.
7. inflammatory bowel disease medical science formula food according to claim 1, is characterized in that described amino acid is: Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.
8. the medical science formula food of inflammatory bowel disease according to claim 1, is characterized in that described carbohydrate is that carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.
9. inflammatory bowel disease medical science formula food according to claim 1, it is characterized in that the described grease of health care that has is: refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix.
10. inflammatory bowel disease medical science formula food according to claim 1, is characterized in that described small peptide is: marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.
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2015
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