CN104839695A - Non-complete nutritional formula food for inflammatory bowel disease - Google Patents

Abstract

The invention belongs to the technical field of medicinal and edible formulas and new resource food, and particularly provides non-total nutrient formula food, specific total nutrient formula food or total nutrient formula food for patients with inflammatory bowel disease; the formula is prepared by reasonably mixing a plurality of traditional Chinese medicines with homology of medicine and food according to the requirements of special medical purpose formula food general rules, combining the physical characteristics of patients with inflammatory bowel diseases and the essence theory of the traditional Chinese medicine, extracting the essence of the traditional Chinese medicine extract with dual purposes of medicine and food, extracting short peptide by biological enzymolysis, prebiotics, amino acid, carbohydrate, grease with health care function, a plurality of vitamins and mineral substances by adopting a plurality of prehydrolysis SBE technologies and the like, can be used as a single nutrient source to meet the nutritional requirements of the patients with inflammatory bowel diseases, and also has the effects of tonifying stomach, promoting the production of body fluid, removing food stagnation, nourishing yin, clearing heat, promoting the circulation of qi and promoting digestion and enhancing immunity.

Description

Non-complete nutritional formula food for inflammatory bowel disease

technical field

The invention belongs to the technical field of medicine and food homologous formula and new resource food, and specifically combines the traditional Chinese medicine essence theory of "medicine and food homologous Chinese medicine" with new resource food, and adds short peptides, prebiotics, amino acids, Carbohydrates, fats with health functions, multi-vitamins, and multi-minerals are complete nutritional formula foods for the prevention and treatment of inflammatory bowel disease, specific complete nutritional formula foods or non-complete nutritional formula foods.

Background technique

Inflammatory bowel disease, referred to as IBD, is a special chronic intestinal inflammatory disease, mainly including Crohn's disease (CD) and ulcerative colitis (UC). In the past 30 years, the incidence of IBD in China has been rising. According to domestic literature reports, the number of cases in the past five years is 8 times that of the same period in the 1990s. IBD has gradually become a common disease in gastroenterology in China. The "chronic enteritis" that many people talk about is probably IBD. The intestinal tract cannot normally absorb carbohydrates, protein, fat, vitamins and various trace elements, and intestinal inflammation or medication may cause poor appetite. Therefore, IBD is often accompanied by different degrees of malnutrition, and even affects children's normal health. Nutritional support plays an important role in relieving IBD symptoms and promoting healing. Therefore, maintaining a good nutritional status is an important part of the treatment of IBD. There is no special diet for IBD. Different people can tolerate different foods. Therefore, the general dietary principle of IBD is to ensure a balanced diet while avoiding some foods that make the disease worse. Many experts believe that inflammatory bowel disease is not terrible, as long as you develop a healthy lifestyle and ensure regular eating, rest, and medication , Regular follow-up and monitoring of the condition. Inflammatory bowel disease is controllable carbohydrates, protein, fat, vitamins and various trace elements. The etiology and pathogenesis of IBD are not yet fully clear. It is known that the abnormal reaction of the intestinal mucosal immune system leads to The inflammatory response plays an important role in the pathogenesis of IBD, which is believed to be caused by the interaction of multiple factors, mainly including environmental, genetic, infection and immune factors. First, environmental factors In recent decades, the incidence of IBD (UC and CD) This phenomenon first appeared in North America and Northern Europe with highly developed socioeconomics, then in Western Europe and Southern Europe, and more recently in Japan and South America. This phenomenon reflects subtle but important changes in environmental factors, such as diet, smoking, etc. Or exposure to other unclear factors. Second, genetic factors. Another important phenomenon in the onset of IBD is that the incidence rate of first-degree relatives of IBD patients is significantly higher than that of the general population, while the incidence rate of the patient's spouse does not increase. A large-scale study in Sweden Studies have found that the incidence of CD in monozygotic twins is significantly higher than that in dizygotic twins. There have been a large number of reports on IBD-related genes. Early studies mainly focused on HLA alleles and cytokine gene polymorphisms, but the reported The results are mixed, which may be related to the genetic background of different races and populations. In recent years, positional cloning of the genome has been carried out. In large-scale studies of IBD families, it has been found that the susceptibility points of IBD are located on chromosomes 3, 7, 12, and 16. Research is still in progress. It is believed that IBD is not only a polygenic disease, but also a genetically heterogeneous disease (different people are caused by different genes). Patients develop diseases due to genetic susceptibility under certain environmental factors. Third, infection The role of microbes in the pathogenesis of IBD has been paid attention to, but so far no specific microbial pathogen has been found to have a constant relationship with IBD. Some studies have suggested that Mycobacterium paratuberculosis and measles virus have a role in CD. Close, but the evidence is not convincing. An alternative view of microbial pathogenicity, which has received increasing attention in recent years, is that IBD (especially CD) is caused by an abnormal immune response against its own normal gut flora, supported by two lines of evidence On the one hand, from the animal model of IBD, the IBD animal model of immunodeficiency caused by transgenic or gene knockout method will not cause intestinal inflammation in the sterile environment of the intestinal tract, but if the normal flora state of the intestinal tract is restored, then Intestinal inflammation occurs,

"The same origin of medicine and food" is one of the most valuable contributions to human beings among the original Chinese medicine; traditional Chinese medicine has always emphasized that "medicine therapy is not as good as diet therapy", and diet therapy has become the best choice for modern people to pursue a return to nature and a healthy diet; let people enjoy Eliminate pain in the process of eating food, avoiding the pain of injections, medicine, and even surgery;

For special nutritional food, there are corresponding regulations and development and application in the United States, the European Union and other developed countries; while my country's GB29922-2013 "General Rules for Formula Foods for Special Medical Purposes" national food safety standard Chinese medical food clearly stipulates: 2.1.1 Full nutritional formula Food: Formula food for special medical purposes that can be used as a single source of nutrition to meet the nutritional needs of the target population; 2.1.2 Specific complete nutritional formula food: formula for special medical purposes that can be used as a single source of nutrition to meet the nutritional needs of the target population under specific diseases or medical conditions food;

At present, there are food-derived short peptides as the main raw material in the market, adding extracts, multivitamins and minerals such as dendrobium, hawthorn, gallinacea, seabuckthorn, papaya, radish, etc., which are used for both medicine and food, to form a compound formula. There are also products that use new resource food as the main raw material, but they have not been found to combine the physical characteristics of patients with inflammatory bowel disease. According to the essence theory of traditional Chinese medicine, it varies from person to person. The golden combination is more than ten kinds of traditional Chinese medicine that can be used for both medicine and food. Extract essence, prebiotics as the main raw materials, complete nutritional formula food made of short peptides, amino acids, carbohydrates, oils with health functions, multivitamins, and compound mineral supplementary materials, specific complete nutritional formula food, non-full nutritional formula food or similar products.

purpose of invention

The purpose of the present invention is to creatively combine a variety of anti-diabetic new resource foods with the extracts of the "medicine and food homologous traditional Chinese medicine" compound, and add short peptides, amino acids, carbohydrates, etc. Compounds, oils with health care functions, multivitamins, and multiminerals are used as auxiliary materials, which can not only supplement the essential nutrients for patients with inflammatory bowel disease, improve the nutritional status of the body, but also use the functional factors in the dual-purpose Chinese herbal medicine to regulate body functions , a complete nutritional formula food, a specific complete nutritional formula food or a non-complete nutritional formula food that is suitable for patients with inflammatory bowel disease, has little toxic and side effects, is safe and effective, and is easily accepted by people.

Invention content:

According to the requirements of the "General Rules for Formulated Foods for Special Medical Purposes", combined with the physical characteristics of patients with inflammatory bowel disease, and comprehensive research results of advanced physiology, medicine, nutrition and clinical application of Harvard University in the United States, according to the "Xiazhong Yuyu" The quintessence theory of traditional Chinese medicine (liver, spleen, and kidney are the principle of harmonization of the three viscera of the liver, spleen, and kidney), using the essence of one or several Chinese medicine extracts that are both medicinal and edible, as well as new resource foods, short peptides, Prebiotics are the main raw materials, amino acids, carbohydrates, fats with health care functions, multivitamins, and compound minerals are used as auxiliary materials. They can not only meet the nutritional needs of patients with inflammatory bowel disease as a single source of nutrition, but also benefit the stomach, promote body fluids, and eliminate accumulation. Full nutritional formula food, specific full nutritional formula food or non-full nutritional formula food (combined compound formula) for stagnation, nourishing yin and clearing heat, promoting qi and eliminating food, and preventing and treating inflammatory bowel disease;

The main component of formula of the present invention is:

1. According to the physical characteristics of diabetic patients, the Chinese medicine extract is based on the principle of the liver, spleen and kidney in the theory of traditional Chinese medicine. The functional factors in the medicinal and edible Chinese herbal medicine are used to regulate the body's function and prevent inflammatory bowel disease. The following major categories of drugs are compatible; among them:

Dendrobium is sweet in taste and slightly cold in nature. It can nourish yin and clear away heat, benefit the stomach and promote body fluid. The lipase contained in hawthorn can promote the digestion of fatty food, promote the secretion of gastric juice and increase the enzymes in the stomach. Hawthorn has the functions of eliminating accumulation and stagnation , astringent and dysentery, promoting blood circulation and removing blood stasis, etc. It is mainly used to treat food stagnation, fullness of the chest, diaphragm, spleen, hernia, blood stasis and amenorrhea. , has the functions of strengthening the myocardium, anti-arrhythmia, and regulating blood lipid and cholesterol levels. Chicken gold is sweet and flat, slightly cold, non-toxic, and belongs to the spleen, stomach, kidney, and bladder meridian. , Indications for eliminating stagnation, invigorating the spleen and stomach. Treat food accumulation, vomiting and nausea. The flavonoids contained in seabuckthorn have high medicinal value, which can lower cholesterol, relieve angina pectoris, and have anti-inflammatory effects. Papaya contains an enzyme that can digest protein. It is beneficial for the human body to digest and absorb food, and has the effect of invigorating the spleen and eliminating food. It contains a large amount of carotene, protein, calcium salt, protease, lemon enzyme, etc., which can prevent and treat inflammation. For dietary stagnation, abdominal distension and pain, constipation, stagnant diarrhea, phlegm stagnation, dyspnea and cough, woody fragrance is pungent, bitter, warm in nature; it returns to the spleen, stomach, and lung meridian, promotes qi and relieves pain; regulates the middle and guides stagnation. Indicates abdominal swelling and satisfaction; epigastric distension and pain; vomiting and diarrhea; severe after dysentery. Qingpi has the effect of soothing the liver and breaking qi, dispelling stagnation and eliminating phlegm. Stomach benefit, dampness, harmonization, anti-pregnancy, used to treat weak spleen and stomach qi, not thinking about eating, Hericium erinaceus can promote qi and eliminate food, invigorate the spleen and appetizer, soothe the nerves and improve intelligence, used for food accumulation, abdominal distension and pain, spleen deficiency Less, insomnia and more dreams,

The medicinal and edible Chinese medicine extract of the present invention refers to dendrobium, hawthorn, gallinacea, seabuckthorn, papaya, radish, woody, green bark, Atractylodes macrocephala, cordyceps sinensis, Cordyceps militaris, ginger, Hericium erinaceus, amomum, Nutmeg, nutmeg, spirulina platensis, pine pollen, malt, gardenia, clove, almond, bergamot, licorice, dark plum, almond, raisin, rice germ, natto, kudzu root, chia seed, psyllium One, several or all of seed shells, Cyclocarya paliurus leaves, tea tree flowers, euglena, tempeh, Cordyceps guangdong, snow lotus culture, milk mineral salt , extracted by biological enzymatic or pre-hydrolyzed SBE and microencapsulated liquefied, spray-dried and freeze-dried extracts were all mixed;

2. Short peptides: oligopeptides, which refer to a class of small molecular proteins that are isolated and extracted from animal or plant proteins by bio-enzyme engineering technology. The average molecular weight is below 1000Dalton, easily soluble in water, stable to acid and heat , can be directly absorbed without digestion, has high bioavailability, and is superior to free amino acids and complete proteins in absorption and utilization. It can be used in protein supplement foods, especially for people with low digestion and absorption capabilities. Short peptides are Excellent nitrogen source. In addition to nutritional functions, short peptides also have a series of physiologically active functions: improving digestion and absorption of the small intestine, enhancing immunity, anti-oxidation, assisting in regulating blood sugar, assisting in regulating blood lipids, assisting in lowering blood pressure, and anti-aging. Radiation, to promote mineral absorption, to enhance the effect of functional factors in Chinese herbal medicines;

The short peptide in the present invention refers to one, several or all of corn oligopeptides, wheat oligopeptides, marine collagen peptides, marine bone peptides, soybean protein peptides, whey protein peptides, and ovalbumin peptides;

3. Prebiotics: To promote intestinal colonization of probiotics, intestinal convergence, lower intestinal pH environment, and not be used by most intestinal spoilage bacteria, but can promote beneficial bacteria in the human body - Lactobacillus, Bifidobacteria growth and reproduction, which can inhibit the growth of spoilage bacteria, and help to improve and maintain the normal function of the intestinal tract; long-term consumption can delay aging, laxative, improve immunity, reduce the burden on the liver, improve the absorption rate of nutrients, especially to improve the body Absorption of calcium, iron, zinc and other metal ions; it can selectively promote the growth and reproduction of beneficial bacteria (bifido, lactic acid), and can also be metabolized into acidic products such as lactic acid and other organic acids, reducing the pH value in the colon and inhibiting The growth of harmful bacteria in the intestinal tract; make the water and electrolyte in the small intestine stay in the intestinal cavity, produce a hypertonic effect, stimulate intestinal peristalsis and cause laxative, thereby promoting the discharge of intestinal toxins and other toxic substances, lactulose can also directly inactivate intestinal Toxins, lower intestinal pH, has been widely used in the treatment of inflammatory bowel disease;

The prebiotics described in the present invention are: Chinese yam, poria cocos, coix seed, gallinacea, Gorgon fruit, extract of inulin, cottonseed oligosaccharide, stachyose, yeast, isomaltooligosaccharide, trehalose, fructooligosaccharide , soybean oligosaccharides, xylooligosaccharides, one, several or all mixed;

4. Carbohydrates: Carbohydrates are composed of three elements: carbon, hydrogen and oxygen. It is the cheapest nutrient among the three main nutrients that provide heat energy for the human body. When ingested sufficiently, it can be rapidly oxidized in the body to provide energy in time , avoid using precious protein to provide energy, carbohydrates are also important components of glycoproteins in cell membranes, glycolipids in nerve tissues, and deoxyribonucleic acid (DNA) that transmit genetic information, and glycogen contained in carbohydrates, when When its reserves in the liver are sufficient, the liver cells have a strong ability to detoxify certain toxic chemicals and toxins produced by various pathogenic microorganisms;

The carbohydrates described in the present invention refer to L-arabinose, fructose, mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast β-glucan, polyfructose, galactose, lactose, glucose, maltose, carbohydrate One, several or all of compounds, fats with health functions, starch, and glycogen are mixed;

5. The oil and ester with health care function means that it has a health care effect on the human body and can increase the energy of the final product, so that the energy contained in every 100g of the final product of the present invention should not be less than 295kJ (70kcal); It can also prevent arteriosclerosis, stroke and heart disease. Fish oil is effective for hypertension, coronary heart disease, stroke, diabetes, rheumatoid arthritis, cancer and other diseases; linseed oil has the effects of losing weight, lowering cholesterol, and improving kidney function; peony seed oil can lower blood fat and blood pressure, and enhance autoimmunity , prevent diabetes and prevent cancer; samara oil has the effect of preventing and treating hypertension, hyperlipidemia, vascular sclerosis and other diseases;

The fats and oils with health care function described in the present invention refer to linseed oil, peony seed oil, samara oil, milk thistle seed oil, phytosterol ester, royal rice oil, tea seed oil, fish oil, fish oil extract, peanut four Alkenic acid oil, sucrose polyester, DHA algae oil, krill oil, Suaeda salsa seed oil, saponica fruit oil, salina fruit oil, medium-chain triglycerides, yellow gelatin, eucalyptus fruit oil, Long handle almond oil, medium and long chain fatty acid edible oil, ingot maple seed oil, epigallocatechin gallate, diglyceride oil, lutein ester, one, several or all mixed;

6. Amino acid: divided into essential amino acid and non-essential amino acid, which is the basic unit of protein, endows protein with specific molecular structure and form, and makes it biochemically active; intake of appropriate amount of methionine is helpful for the metabolism of various sulfur-containing compounds in the human body And the methyl group contained in it can detoxify toxic substances or drugs through methylation; leucine can repair muscles, control blood sugar, and provide energy to body tissues; the essential amino acid phenylalanine can inhibit cancer growth, and can reduce the toxic and side effects of drugs, lysine can improve the absorption and utilization of food protein, achieve balanced nutrition, and promote growth and development; arginine helps to convert ammonia in the blood into urea and excrete it; for high Ammoniaemia, liver dysfunction, etc. are effective; histidine reduces the acidity of gastric juice, relieves the pain of gastrointestinal surgery, relieves vomiting during pregnancy and stomach burning sensation, inhibits digestive tract ulcers caused by autonomic nervous tension, and is effective for allergies Diseases, such as asthma, are also effective; tryptophan can prevent pellagra, depression, improve sleep and regulate mood;

Amino acid in the present invention refers to L-glutamine, γ-aminobutyric acid, pearl peptide powder, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histamine Acid, tryptophan, citrulline, ornithine, taurine, one, several or all mixed;

7. Vitamins and minerals: vitamins and minerals are essential nutrients for the human body, and the vitamins added in the present invention are vitamins and minerals are essential nutrients for the human body;

The vitamins added in the present invention are vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin Be, vitamin Bu, niacin, folic acid, pantothenic acid, One, several or all of choline and biotin are mixed;

The minerals added in the present invention are calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum, one, several or all of them mixed. The mineral is added as an organic or inorganic compound of the mineral;

The amount of added vitamins and minerals in the present invention is implemented with reference to the "General Rules for Formulated Foods for Special Medical Purposes". Now taking 1000g of finished products as an example, the added amounts are 0.01g of vitamin A, 0.000015g of vitamin D, 0.12g of vitamin E, 0.0075g of vitamin K, Vitamin K10.00001g, vitamin C10.625g, vitamin B10.016g, vitamin B20.016g, vitamin B60.015g, vitamin B0.0023g, vitamin Be, vitamin Bu, niacin 0.2g, folic acid 0.003g, pantothenic acid 0.051g, bile Alkali 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, Iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g;

8. Use the above-mentioned integrated innovative process to mix various ingredients evenly to make powdered solid beverages and granules, and pack them into 10g/bags, dissolve them in about 150ml of boiling water, drink them directly or take them through nasal feeding; you can also add Appropriate amount of additives are made into capsules, tablets, or sweeteners and black sesame powder are added to make quick and convenient food such as biscuits, which are easy to carry and eat when going out. Packed into 10-65ml/bottle, drink one bottle every morning, noon, and 0.5 hours after dinner, all operations are carried out in a clean and dry environment;

The characteristics of this non-complete nutritional formula food and its effects on the body are mainly manifested in the following aspects:

1. The present invention is developed according to the requirements of "General Rules for Formulated Foods for Special Medical Purposes", combined with the physical characteristics of patients with inflammatory bowel disease, and the research results of advanced physiology, medicine, nutrition and clinical application of Harvard University in the United States. Different people, golden combination;

2. The present invention is based on the quintessence theory of traditional Chinese medicine (liver, spleen, and kidney are the main principle of the same coordination of the liver, spleen, and kidney) based on the essence theory of "dispelling the middle and nourishing" and "balanced recuperation", and adopts a variety of medicinal and edible Chinese medicine extract essences, short-term Peptide is the main raw material, prebiotics, carbohydrates, amino acids, fats with health functions, multi-vitamins and minerals are used as auxiliary materials. The organic combination of various ingredients integrates various functions, and through the effective ingredients. Synergistic effect, enhance the effect;

3. It has high absorbability. Using the formula of the present invention, the food prepared with appropriate proportions of various components will be in an isotonic state after being dissolved in a certain amount of water, and can quickly pass through the stomach to the small intestine, absorb quickly and completely, and can quickly Supplement the nutrition needed by patients with inflammatory bowel disease without increasing the burden on liver and kidney;

4. The formula of the present invention adopts the extracts of various medicinal and edible Chinese herbal medicines, and contains a variety of functional active ingredients, which not only increases the concentration of functional factors, reduces the intake of various impurities, and helps to reduce the burden on the liver and kidneys, it has It has the effect of enhancing the body's resistance, and it also has the effects of benefiting the stomach and promoting body fluid, eliminating stagnation, nourishing yin and clearing heat, promoting qi and eliminating food, and preventing and treating inflammatory bowel disease;

5. The formula food of the present invention uses food-derived bioactive short peptides from various sources as the nitrogen source, because short peptides can be absorbed without digestion, which is more conducive to the utilization of the body, and can effectively improve the negative nitrogen balance of patients with inflammatory bowel disease , and food-derived short peptides can improve the structure and function of intestinal mucosal epithelial cells, and improve the absorption capacity of intestinal mucosa;

6. The prebiotics contained in the formula of the present invention can inhibit the growth of spoilage bacteria by promoting the growth and reproduction of probiotics in the intestine, and at the same time form a protective barrier on the surface of the intestinal mucosa, which can resist the damage of intestinal spoilage bacteria to the intestinal mucosa , reduce the absorption of harmful substances in the intestines, promote intestinal peristalsis, accelerate the discharge of residual substances in the intestines, prevent constipation, and enhance the body's immunity by promoting the growth and reproduction of intestinal probiotics, short peptides and active polysaccharides and other biologically active substances have a synergistic effect;

7. The carbohydrates contained in the formula of the present invention are three main nutrients that provide heat energy for the human body. They can be oxidized rapidly in the body to provide energy in time, and avoid using valuable protein to provide energy. Carbohydrates are also glycoproteins of cell membranes, Glycolipids in nervous tissue and important components of deoxyribonucleic acid (DNA) that transmit genetic information, and glycogen contained in carbohydrates, when it is fully stored in the liver, liver cells are resistant to certain toxic chemicals and various The toxin produced by a pathogenic microorganism has a strong detoxification ability;

8. The oil with health-care function contained in the formula of the present invention not only has a health-care effect on the human body, but also provides the human body with the energy required for normal life, so that the energy contained in every 100g of the final product of the present invention should not be less than 295kJ (70kcal);

9. The amino acid contained in the formula of the present invention is the basic unit of protein, endows protein with specific molecular structure, makes it have biochemical activity, helps the metabolism of various sulfur-containing compounds in the human body and the formazan contained in it The base can detoxify toxic substances or drugs by methylating them. It can repair muscles, control blood sugar, and provide energy to body tissues. It can also improve the absorption and utilization of food protein, achieve balanced nutrition, and promote growth and development;

10. The formula food of the present invention contains a variety of vitamins and minerals, which can quickly supplement the micronutrients needed by patients with inflammatory bowel disease. After the short peptide is chelated with calcium, iron, zinc, etc., the content of mineral elements is increased. Absorption rate;

11. The formula of the present invention does not contain fat and cholesterol, and can not increase the intake of fat and cholesterol while supplementing protein and micronutrients, and avoids the adverse effects of high-protein foods such as meat and eggs.

Detailed ways

The present invention will be further described below through the following examples, which will help to understand the present invention.

Implementation Case 1

To achieve the purpose of the present invention, the non-complete nutritional formula food for inflammatory bowel disease is based on the physical characteristics of patients with inflammatory bowel disease, and according to the essence theory of traditional Chinese medicine, it varies from person to person. Dual-purpose traditional Chinese medicine extract essence, new resource food, and prebiotics are the main raw materials, and one, several or all short peptides, carbohydrates, amino acids, oils with health care functions, multi-vitamins, and multi-minerals are used as auxiliary materials Complete nutritional formula, or specific complete nutritional formula food and non-complete nutritional formula food;

Formulated according to the following raw materials and their dosage, extracts for medicinal and edible purposes and new resource food: Dendrobium 12g, hawthorn 12g, gallinaceae 11g, seabuckthorn 11g, papaya 10g, radish seed 10g, woody fragrance 8g, green bark 8g, Atractylodes macrocephala 8g, Cordyceps sinensis 7g, Cordyceps militaris 7g, Ginger 6g, Hericium erinaceus 6g, Amomum 6g, Yizhiren 6g, Nutmeg 5g, Spirulina platensis 5g, Pine pollen 5g, Malt 5g, Gardenia 4g, Clove 4g, 4g almonds, 3g bergamot, 3g licorice, 3g black plum, 3g almonds, 3g raisins, 3g germ rice, 3g natto, 3g kudzu root, 3g chia seeds , 3g psyllium husk , 2g paliurus leaves , tea tree flowers 2g , Euglena 2g , Tempeh 2g , Guangdong Cordyceps 2g , Snow Lotus Culture 1g, Milk Mineral Salt 1g, Short Peptide 200g, Prebiotics 100g, Various Amino Acids 100g, Carbohydrates 100g, Healthy Oils 100g, Vitamin A0.01g, Vitamin D0.000015g, Vitamin E0.12g, Vitamin K0.0075g, Vitamin K10.00001g, Vitamin C10.625g, Vitamin B10.016g, Vitamin B20.016g, Vitamin B60.015g, Vitamin B0.0023g, Vitamin Be, vitamin Bu, niacin 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, Iron 0.15g, Zinc 6.2g, Selenium 0.00012g, Copper 0.007g, Manganese 0.018g, Iodine 0.00001g, Fluorine 0.00001g, Chromium 0.00001g, Molybdenum 0.00001g;

When making it, Dendrobium, hawthorn, gallinacea, seabuckthorn, papaya, radish, woody, green bark, Atractylodes ginger, Hericium erinaceus, amomum, Yizhiren, nutmeg, spirulina platensis, pine pollen , malt, gardenia, clove, almond, bergamot, licorice, ebony, almond, raisin, rice germ, natto, chia seed, psyllium husk, papaya leaf, tea tree flower, euglena, tempeh After soaking, add β-cyclodextrin, extract by pre-hydrolysis SBE technology, and spray-dry the powdery substance, then add short peptides, prebiotics, amino acids, Cantonese Cordyceps, Cordyceps sinensis, pupae Cordyceps, kudzu root, snow lotus culture, milk mineral salts , carbohydrates, oils with health functions, multi-vitamins and minerals are crushed and mixed together, then sterilized at 120 degrees Celsius for 1 hour, and then mixed evenly to make a powdered solid drink , granules, and divided into 10g/bag, dissolved in about 150ml of boiling water, drink directly or ingested through nasal feeding; it can also be made into capsules, tablets or sweeteners and black sesame powder by adding appropriate amount of additives Quick and convenient food such as biscuits is easy to carry and eat when going out. If it is made into a beverage, spray drying and less auxiliary materials are added, and it is divided into 10-65ml/bottle. Drink 1 bottle each morning, noon, and 0.5 hours after dinner. , all operations are carried out in a clean and dry environment that meets the requirements of the Good Manufacturing Practice for Formula Foods for Special Medical Purposes.

Implementation Case 2

The above inflammatory bowel disease non-complete nutritional formula food also includes the following components by weight, extracts for both medicine and food: Cordyceps militaris 7g, ginger 6g, Hericium erinaceus 6g, Amomum 6g, Yizhiren 6g, meat 5g cardamom, 5g spirulina platensis, 5g pine pollen, 5g malt, 4g gardenia, 4g clove, 4g almond, 3g bergamot, 3g licorice, 3g ebony, 3g almond, 3g raisin, 3g germ rice, 3g natto, kudzu root 3g, chia seeds 3g , psyllium husk 3g , Cyclocarya paliurus leaves 2g , tea tree flowers 2g , euglena 2g , tempeh 2g , guangdong cordyceps 2g , snow lotus culture 1g, milk mineral salt 1g , prebiotics 350g, 150g of short peptides, 100g of various amino acids, 100g of carbohydrates, 100g of oils and fats with health functions, 50g of carbohydrates, oils with health functions, 25g of vitamins and minerals.

Implementation Case Three

The above-mentioned inflammatory bowel disease non-complete nutritional formula food also includes the following components by weight: several medicinal and edible Chinese medicine extract essences and new resource foods 500g, prebiotics 450g, short peptides 200g, 150g fat, 150g amino acid, 25g multivitamins, 25g multiminerals; the energy contained in each 100g should not be less than 295kJ (70kcal).

Implementation Case 4

The above-mentioned inflammatory bowel disease non-complete nutritional formula food also includes the following components by weight: 500g of medicinal and edible Chinese medicine extract essence and new resource food, 450g of prebiotics, 300g of carbohydrates, 250g of short peptides, 150g of amino acids, 25g of multivitamins and 25g of multiminerals; the energy contained in each 100g should not be less than 295kJ (70kcal).

Implementation Case Five

The above-mentioned inflammatory bowel disease non-complete nutritional formula food also includes the following components by weight: medicinal and edible dual-purpose traditional Chinese medicine extract essence and new resource food 500g, prebiotics 480g, short peptides 250g, carbohydrates 250g, with health care functions 150g of fat, 25g of multivitamins, and 25g of multiminerals; the energy contained in each 100g should not be less than 295kJ (70kcal).

Claims (10)

1. inflammatory bowel disease non-fully nutritional formulas, it is characterized in that the constitutive character in conjunction with patients with inflammatory bowel, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, prebiotics for primary raw material, with a kind of, several or whole small peptides, carbohydrate, amino acid, the full nutrient formulation that has the grease of health care, multivitamin, several mineral materials to make for auxiliary material, or make specific full nutritional formulas and non-fully nutritional formulas;

Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: stem of noble dendrobium 12g, hawthorn 12g, the membrane of a chicken's gizzard 11g, sea-buckthorn 11g, pawpaw 10g, radish seed 10g, banksia rose 8g, rascal 8g, bighead atractylodes rhizome 8g, Cordyceps sinensis 7g, Cordyceps militaris 7g, ginger 6g, Hericium erinaceus 6g, fructus amomi 6g, fructus alpiniae oxyphyllae 6g, nutmeg 5g, blunt top spirulina 5g, pollen pini 5g, Fructus Hordei Germinatus 5g, cape jasmine 4g, cloves 4g, almond 4g, Buddha's hand 3g, Radix Glycyrrhizae 3g, dark plum 3g, almond 3g, raisins 3g, rice germ 3g, natto 3g, root of kudzu vine 3g, strange sub-seed3g , circle luxuriant isapgol husk3g , Qingqian Willow leaf2g , Tea Flower2g , Euglena2g , sky shellfish2g , Guangdong Cordyceps militaris2g , Saussurea involucrata culture 1g, newborn mineral salt1g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

During making first will be the stem of noble dendrobium, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, radish seed, the banksia rose, rascal, bighead atractylodes rhizome ginger, Hericium erinaceus, fructus amomi, fructus alpiniae oxyphyllae, nutmeg, blunt top spirulina, pollen pini, Fructus Hordei Germinatus, cape jasmine, cloves, almond, Buddha's hand, Radix Glycyrrhizae, dark plum, almond, raisins, rice germ, natto, strange sub-seed, the luxuriant isapgol husk of circle, Qingqian Willow leaf, Tea Flower, Euglena, sky shellfishadd cycloheptaamylose after immersion, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, guangdong Cordyceps militaris,cordyceps sinensis, Cordyceps militaris, the root of kudzu vine, saussurea involucrata culture, newborn mineral salt, carbohydrate, have the grease of health care, multivitamin and mineral matter to be pulverized and mixed together after carry out 120 celsius temperature sterilizing 1 hour, then solid beverage, the granule of making powdery is mixed, and be distributed into 10g/ bag, after about 150ml dissolved in boiled water, directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

2. inflammatory bowel disease non-fully nutritional formulas according to claim 1, the marrow also comprised according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, prebiotics for primary raw material, with a kind of, several small peptides, the non-fully nutritional formulas that has the grease of health care, amino acid, multivitamin, several mineral materials to make for auxiliary material, or make specific full nutritional formulas and full nutritional formulas.

3. inflammatory bowel disease non-fully nutritional formulas according to claim 1, the marrow also comprised according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several medicinal and edible Chinese medicine extract essences and new resource food, prebiotics for primary raw material, carbohydrate, small peptide, amino acid, multivitamin, several mineral materials are the non-fully nutritional formulas that auxiliary material is made, or make full nutritional formulas and full nutritional formulas.

4. inflammatory bowel disease non-fully nutritional formulas according to claim 1, the marrow also comprised according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, prebiotics for primary raw material, small peptide, carbohydrate, there are the grease of health care, multivitamin, several mineral materials to be the non-fully nutritional formulas that auxiliary material is made, or make specific full nutritional formulas and full nutritional formulas.

5. inflammatory bowel disease non-fully nutritional formulas according to claim 1, is characterized in that described medicine-food two-purpose Chinese herbal medicine extract and new resource food are: the stem of noble dendrobium, hawthorn, the membrane of a chicken's gizzard, sea-buckthorn, pawpaw, radish seed, the banksia rose, rascal, bighead atractylodes rhizome ginger, Hericium erinaceus, fructus amomi, fructus alpiniae oxyphyllae, nutmeg, blunt top spirulina, pollen pini, Fructus Hordei Germinatus, cape jasmine, cloves, almond, Buddha's hand, Radix Glycyrrhizae, dark plum, almond, raisins, rice germ, natto, strange sub-seed, the luxuriant isapgol husk of circle, Qingqian Willow leaf, Tea Flower, Euglena, sky shellfish, guangdong Cordyceps militaris,cordyceps sinensis, Cordyceps militaris, the root of kudzu vine, saussurea involucrata culture, newborn mineral saltone wherein, several or all mix.

6. inflammatory bowel disease non-fully nutritional formulas according to claim 1, is characterized in that described small peptide is: marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.

7. inflammatory bowel disease non-fully nutritional formulas according to claim 1, it is characterized in that described prebiotics is: the extraction mixture of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, trehalose, stachyose, yeast, oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix.

8. inflammatory bowel disease non-fully nutritional formulas according to claim 1, is characterized in that described amino acid is: Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

9. the non-fully nutritional formulas of inflammatory bowel disease according to claim 1, is characterized in that described carbohydrate is that carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

10. inflammatory bowel disease non-fully nutritional formulas according to claim 1, it is characterized in that the described grease of health care that has is: refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix.