CN104146254A

CN104146254A - Full-nutrition formulated food for hypertension

Info

Publication number: CN104146254A
Application number: CN201410399332.1A
Authority: CN
Inventors: 胡安然
Original assignee: 胡安然
Current assignee: Hangzhou jinshanmei Health Management Co.,Ltd.
Priority date: 2014-08-14
Filing date: 2014-08-14
Publication date: 2014-11-19
Anticipated expiration: 2034-08-14
Also published as: CN104146254B

Abstract

The present invention provides full-nutrition formulated food, special full-nutrition formulated food or non-full nutrition food for hypertension patients to eat. The formula is developed according to the requirement of "General principles of formulated food for special medical purposes", integrating the present research achievement of advanced physiology, medicine, nutrition, clinical applications and the like in Harvard university, United States, and based on the essential theory (liver, spleen, kidney simultaneously regulating as the main principle) of "communicating while tonifying" and "balanced nursing". The present product adopts a plurality of medical and edible Chinese herbal essence extracts and a plurality of probiotics and oligopeptides as main raw materials, and adopts prebiotics, carbohydrates, amino acids, a plurality of vitamins and minerals as auxiliary materials. The main raw materials and the auxiliary materials are mixed to prepare the product. The full-nutrition formulated food not only can be used as a sole source of nutrition to meet the nutritional needs of patients with hypertension, but also has efficacy of pacifying liver and benefiting vital energy, promoting blood circulation to restore menstrual flow, lowering lipid and losing weight, nourishing blood and liver, benefiting essence and moisturizing dryness, activating blood circulation and removing blood stasis, and vasodilatating.

Description

The full nutrient formulation food of hypertension

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " medicine among integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds to take the full nutrient formulation food of hypertension, specific full nutrient formulation food or the non-full nutrient formulation food that small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter make as auxiliary material.

Background technology

Hypertension is the disease that continues hyperpiesia, can cause apoplexy, heart disease, hemangioma, the diseases such as kidney failure, hypertension is a kind ofly to take angiosthenia rising as feature, can be with heart, blood vessel, the systemic disease of the functional or organic change of brain and kidney and other organs, it has dividing of essential hypertension and secondary hypertension, do not using in antihypertensive situation, contraction >=139mmHg and/or diastolic pressure >=89mmHg, by blood pressure level, hypertension is divided into 1, 2, 3 grades, systolic pressure >=140mmHg and diastolic pressure <90mmHg are single-row is isolated systolic hypertension, patient previously has history of hypertension, using at present antihypertensive, although blood pressure is lower than 140/90mmHg, also should be diagnosed as hypertension, the reason of hypertension incidence is a lot, 1. age: the incidence of disease has the trend increasing with age growth, within 40 years old, above person's incidence of disease is high, 2. salt: take in the many persons of salt, Hypertension incidence is high, there is the salt of thinking <2g/ day, there is hardly hypertension, 3-4g/ day, Hypertension incidence 3%, 4-15g/ day, the incidence of disease 33.15%, the >20g/ day incidence of disease 30%, 3. body weight: overweight people's incidence of disease is high, 4. heredity: approximately half hyperpietic has family history, 5. environment is with professional: the working environment that has noise, all easily there is hypertension in overwrought mental labour, the high pressure incidence of disease in city is higher than rural area, if the hypertension of chronicity does not obtain suitable treatment, can increase the load of heart, damage blood vessel, even cause apoplexy, heart disease, kidney failure and PVR, even can be blind, also there will be complication: 1, hypertension encephalopathic: can cause encephaledema and intracranial hypertension, cerebral hemorrhage, 2, hypertensive heart disease: can cause coronary atherosclerosis, then there is angina pectoris, in heart failure etc., 3, hypertension ephrosis: cause albuminuria, blood urine, " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science, the traditional Chinese medical science always emphasize " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet, allow people dispel slight illness in the process of enjoying cuisines, avoided having an injection, taking medicine, even the hardship of operation.

For food of special nutrients, in developed countries such as the U.S., European Union, there are corresponding regulation and Application and Development; And wholefood is clearly stipulated in China GB29922-2013 < < special medicine purposes formula food general rule > > food security national standard: the full nutrient formulation food of 2.1.1: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutrient formulation food: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition.

Traditional Chinese medical science traditional medicine is thought: " spleen (being digestive system) is the foundation of acquired constitution ", stomach health is healthy basis, and 99% of human nutrition need to lean on intestinal absorption, and in intestines, disease is also the source of ten thousand diseases; But along with the age is larger, profitable strain in enteron aisle (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% period infant, during to the middle age, be down to and only account for 5% in 10%, 65 years old later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies show that, normal flora has many irreplaceable effects in human body digestion, immunity and the aspect such as disease-resistant; The generation development of change and various diseases, particularly intestines problem that gut flora forms is closely related, and finds from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is a kind of control method of intervening safely and effectively.

The relation of hypertension and probiotics: the Cardiovascular Center of Tokyo hospital is after taking the y-aminobutyric acid milk beverage that contains certain probiotics fermention generation to 39 moderate hypertension patients, measured their blood pressure, when y-aminobutyric acid content reaches 0.5mg/kg, can significantly reduce blood pressure, y-aminobutyric acid, it is the natural amino acid that a kind of nonprotein forms, mainly be present in mammal brain, in spinal cord, it is a kind of important inhibiting nerve transmitter substance, if the synthetic or supplementary y-aminobutyric acid of foreign aid in human body, just can play and suppress central nervous system excitement, the effect of reducing blood pressure, Dalian Medical Univ has carried out external ACE and has suppressed active bacterial strain screening experiment, from 40 strain bacterium, screen the probio that 7 strains have antihypertensive activity, there is the ACE inhibiting rate of 6 strain bacterium to reach more than 50%, have a kind of small peptide being mainly found in Lactobacillus helveticus acidified milk to be also active A CE(ACE) peptide for inhibiting, angiotensinⅡ can make vessel retraction, the effect that blood pressure raises, the principle of Vel-Tyr-Pro-Trp-Thr-Gln-Arg-Phe is to be converted into angiotensinⅡ by suppressing angiotensinⅠ, thereby improve blood flow and blood pressure.

Though directly probiotic oral has certain effect, but because probio one cannot field planting in enteron aisle, and stop, occupy-place are seldom, easily run off, and withdraw rear harmful bacteria and easily recur, and associated patient needs long-term taking, and treatment cycle is long, often uses rear recurrence rate very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by studying the key technology of probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts to seek to improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can be played field planting effect, the enteron aisle adhesive capacity of the reduction of enteron aisle pH environment and raising probiotic cell etc., based on above-mentioned key element, suitable food materials screen from tens of kinds " medicines among integration of drinking and medicinal herbs " in this seminar, found first interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., external source probio is had to very strong field planting effect, for the prescription of probio in enteral microecological formulation selects to provide experimental basis.

Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter form compound prescription, utilize in addition the product that probio is primary raw material, but also do not find the constitutive character in conjunction with hyperpietic, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutrient formulation food that auxiliary material is made, specific full nutrient formulation food or similar products.

goal of the invention

The object of the invention is inheriting on the theoretical treatment method of traditional Chinese medical science marrow, the initiative probio by multiple raising hyperpietic immunity combines with the extract of " medicine among integration of drinking and medicinal herbs " compound, interpolation is with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, not only can supplement and exempt from hyperpietic institute essential nutrients, improve body nutrition condition, can also and utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutrient formulation food of the acceptable applicable edible for patients with elevated blood pressure of people, specific full nutrient formulation food or non-full nutrient formulation food.

summary of the invention:

This R&D team is according to the requirement of < < special medicine purposes formula food general rule > >, in conjunction with hyperpietic's constitutive character, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears is mended ", theoretical (the liver of marrow of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, the dirty same main principle that is adjusted to of kidney three), adopt the Chinese medical extract elite of 3 kinds of above medicine-food two-purposes, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets hyperpietic, also has flat liver benefit gas, promoting blood circulation for regulating menstruation, lowering blood-fat and reducing weight, the soft liver of enriching blood, benefit essence is moisturized, activate blood circulation and disperse blood clots and the full nutrient formulation food of hemangiectasis effect, specific full nutrient formulation food or non-full nutrient formulation food (compound prescription being combined into).

The main component of the present invention's formula is:

1. Chinese medical extract is that the liver,spleen,kidney from theory of traditional Chinese medical science three is dirty with being adjusted to main principle according to hyperpietic's constitutive character, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and choose following several large class medicine and carry out compatibility; Wherein: the flat liver benefit of rhizoma Gastrodiae gas, sharp waist knee, strengthening the bones and muscles, to coronary artery, peripheral vascular, there is dilating effect to a certain degree can increase periphery and coronary blood flow, heart is had to protective effect; Bark of eucommia filling liver kidney, strengthening the bones and muscles, controls spinal column ache, foot and knee flaccidity, dribbling urination, hypertension; The red sage root thoughts of returning home, Liver Channel, can stasis-dispelling and pain-killing, promoting blood circulation for regulating menstruation, lowering blood-fat and reducing weight, relieving restlessness clears away heart-fire.The effect that Ligusticum wallichii has promoting the circulation of qi, dispels the wind, invigorates blood circulation, can promoting blood circulation, activating QI to alleviate the depression, wind-expelling pain-stopping; The root of herbaceous peony is cool in nature, and bitter acid, is slightly cold, and has the soft liver of enriching blood, flat liver pain relieving; Radix et Rhizoma Gynurae divaricatae is lightly seasoned, property is flat, has the effect of hypoglycemic, clearing heat and cooling blood, promoting blood circulation and stopping pain; Glossy ganoderma is coronary artery dilator effectively, increases CF, improves Myocardial Microcirculation, strengthens the supply of myocardium oxygen and energy, and myocardial ischemia is had to protective effect; Selfheal is cold in nature, and sweet, pungent, the micro-hardship of taste has the effect of letting out clearly irascibility, mass dissipating and swelling eliminating, clearing heat and detoxicating, expelling phlegm and arresting coughing, cooling blood and hemostasis; Corn stigma is flat, taste is sweet, returns bladder, liver, gallbladder channel, has diuresis, accelerates circulatory system running and fall hypoglycemic effect; Lophatherum gracile taste is sweet, cold in nature, cures mainly disease heat, cough with dyspnea, haematemesis, hot malicious wind, dissolving phlegm in the heart, controls fanatical unhappiness, a pain wind; Hawthorn has the long-pending effect stagnant, that convergence stops dysentery, activates blood circulation and disperses blood clots of spending that disappears, and contained mountain terpene and flavonoids have significant hemangiectasis and hypotensive effect;

Medicinal and edible Chinese medicine extract of the present invention and new resource food refer to the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, the bark of eucommia, rhizoma Gastrodiae, the red sage root, Ligusticum wallichii, the root of herbaceous peony, Radix et Rhizoma Gynurae divaricatae, lucidum spore powder (broken wall), glossy ganoderma, the Radix Astragali, selfheal, corn stigma, Sessileflower Acanthopanax Bark, Radix puerariae, hawthorn, peach kernel, lophatherum gracile, cornus officinalis sieb et zucc, chrysanthemum, cassia seed, sealwort, Radix Glycyrrhizae, matrimony vine, Poria cocos, oyster, earthworm albumen powder, natto, red yeast rice, rape pollen, CLA, phosphatidylserine, algae extrats wherein 3 kinds is above or all, adopt biological enzymolysis or prehydrolysis SBE to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract.

2. many kinds of probios: make probio arrive enteron aisle by most of strong acid environment by stomach, to promote the propagation of probio, regulate microecological balance in intestines, promotion is to micro-absorption, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body field planting drag or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, can obviously reduce the level of intestinal endotoxemia the generation of preventing liver injury; It is also the important measures of adjusting intestinal microecology that selective enteron aisle decontamination is dyed, and has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by suppressing urease-producing in enteron aisle and producing the growth of ammonium bacteria, builds up resistance;

Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, Bifidobacterium wherein: refer to that bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum are wherein a kind of, several or all mix; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus be a kind of, several or all mixing wherein.

3. small peptide: be oligopeptide, refer to the small molecule protein that utilizes bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need through digestion and directly absorb, bioavailability is high, in absorption and utilization, be better than free amino acid and complete protein, can be applicable in Protein intake food, especially for the low crowd of abilities of digestive and absorption, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function that improves small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.

4. prebiotics: to urge the field planting of probio enteron aisle, enteron aisle convergence, to reduce enteron aisle pH environment, by most enteron aisle spoilage organisms, do not utilized yet, but can promote beneficial bacteria---the growth and breeding of lactobacillus, Bifidobacterium in human body, thereby can suppress spoilage organisms growth, contribute to improve and maintain enteron aisle normal function; Long-term edible can delay senility, defaecation, raising immunity, alleviate burden of liver, improve the absorptivity of nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, pH value in colon is reduced, the growth of inhibition harmful intestinal tract bacterium; Make Water-Electrolyte in small intestine be trapped in enteric cavity, produce the high effect of oozing, stimulate enterocinesia to cause laxative, thereby promote the discharge of intestinal endotoxin and other toxicants, lactulose also directly endotoxin in deactivation enteron aisle, reduce enteron aisle pH value, extensively model is applied to antihypertensive therapy;

Prebiotics of the present invention is 2 classes

A. external source probio is had to very strong field planting effect prebiotics: several or all mixing wherein of the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast;

B. common prebiotics: wherein a kind of, several of oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide or all mix;

Originally refer to a kind of, several or all mixing wherein of oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide.

5. carbohydrate: carbohydrate is by carbon, three kinds of elements of hydrogen and oxygen form, it be for human body provide three kinds of heat energy main nutrient in the most cheap nutrient, while taking in abundance, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA conveying hereditary information (DNA), and the glycogen containing in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms,

Carbohydrate of the present invention refers to a kind of, several or all mixing wherein of glucose, fructose, galactolipin, lactose, glucose, maltose, Arabinose, water-soluble dietary fiber, starch, glycogen.

6. amino acid: being divided into essential amino acid and nonessential amino acid, is the base unit that forms protein, gives protein specific molecular morphosis, makes it have biochemical activity; Absorbing appropriate methionine contributes to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and the effect of playing removing toxic substances; Leucine can be repaired muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress the growth of cancer knurl, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to the ammonia in blood change urea into and excrete out; For hyperammonemia, liver dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses alimentary canal nervous by vegetative nerve and that cause and festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improves sleep and regulates mood;

Amino acid of the present invention refers to a kind of, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.

7. vitamin and mineral matter:

Vitamin and mineral matter are the nutrients of needed by human, and the vitamin adding in the present invention is that vitamin and mineral matter are the nutrients of needed by human;

The vitamin adding in the present invention is a kind of, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin;

The mineral matter adding in the present invention is a kind of, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals is used sanitary standard > > with reference to GB14880 < < food enrichment, GB2760 < < food additives are used standard > > to carry out, and now take 1000g finished product as example, and addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

8. the present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, mix with the Chinese medical extract after biological enzymolysis or the extraction of prehydrolysis SBE technology microencapsulation processing again, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and by gastric juice, arrive in enteron aisle and stop field planting smoothly by oral, the antihypertensive effect of product is compared with market like product significantly and improved.

9. adopt above-mentioned integrated innovation technique various batchings to be mixed to solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets the good production standard of < < special medicine purposes formula food > > requirement.

The characteristic of this full nutrient formulation food of filling a prescription and the effect of body is mainly manifested in to the following aspects:

1. the present invention is according to the requirement of < < special medicine purposes formula food general rule > >, constitutive character in conjunction with hyperpietic, the achievement in research developments such as advanced physiology, medicine, nutrition and clinical practice of comprehensive nowadays American Harvard University, vary with each individual, gold compatibility.

2. the present invention is according to the marrow of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of " theoretical (liver,spleen,kidney three is dirty with being adjusted to main principle), adopting the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, take prebiotics, carbohydrate, amino acid, multivitamin and mineral matter as auxiliary material, the organic assembling of various batchings, various functions are merged, and by the synergy between active ingredient, humidification effect.

3. have efficient absorption, utilize formula of the present invention, various components adopt the food of suitable ratio collocation preparation, the state that oozes such as after a certain amount of water-soluble solution, be, can by stomach, arrive small intestine fast, absorption fast, completely, can supplement rapidly hyperpietic's desired nutritional.

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicines, contain several functions active component, not only improved the concentration of function factor, reduce the absorption of various impurity, contribute to alleviate liver kidney burden, there is the effect that strengthens resistance of human body, have in addition flat liver benefit gas, promoting blood circulation for regulating menstruation, lowering blood-fat and reducing weight, the soft liver of enriching blood, beneficial essence to moisturize, activate blood circulation and disperse blood clots and hemangiectasis effect.

5. contained probio in the present invention formula, multiple probio can be safeguarded enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and the absorption of raising body to calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve the tolerance of host to radioactive ray, lactobacillus significantly increases intestinal mucosa immunoglobulin A (SIgA) content, body intestinal mucosa local immunity is had to regulating action, regulate stomach, the micro-ecology of intestines, can improve calcium, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, can also reduce the absorption of cholesterol.

6. to take the food source inhibition biological active small peptide in multiple source be nitrogenous source to formula food of the present invention, because small peptide does not need digestion to absorb, more be conducive to the utilization of body, can effectively improve hyperpietic's negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, the absorbability of raising intestinal mucosa.

7. this prescription adopts Liao Ben team by the achievement to the key technology research of probio field planting mechanism in enteron aisle over nearly 3 year, improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence that combines prebiotics can be played the reduction of field planting effect, enteron aisle pH environment and the key elements such as enteron aisle adhesive capacity of raising probiotic cell, so the composition of this food formula has strengthened the field planting effect to external source probio greatly.

8. contained prebiotics in the present invention formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; on intestinal mucosa surface, form one protective barrier simultaneously; can resist the damage of enteron aisle spoilage organisms to intestinal mucosa; reduce the absorption of intestinal toxic material; can also promote intestines peristalsis; accelerate the discharge of residuals in intestines; can prevent constipation; and by promoting the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.

9, in the present invention formula contained carbohydrate be for human body provide three kinds of heat energy main nutrient, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA (DNA) that conveys hereditary information, and the glycogen containing in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms.

10, contained amino acid in the present invention's formula, it is the base unit that forms protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and play the effect of removing toxic substances, can repair muscle, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.

11, formula food of the present invention containing multivitamin and mineral matter, can supplement rapidly the required micronutrient of hyperpietic, small peptide by the chelating with calcium, iron, zinc etc. after, more increased the absorptivity of mineral matter element.

12, not fatty and cholesterol in the present invention's formula can not increase the absorption of fat, cholesterol in supplementary protein, micronutrient, has avoided the adverse effect of the high protein diets such as meat, egg.

The specific embodiment

Below by following examples, the invention will be further described, and it will contribute to understand the present invention.

Embodiment mono-

Realizing the full nutrient formulation food of the object of the invention hypertension is with the constitutive character in conjunction with hyperpietic, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, it is primary raw material that gold compatibility be take Chinese medical extract elite, multiple probio, the small peptide of 6 kinds of above medicine-food two-purposes, take the food that prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials make as auxiliary material;

By following raw materials according and consumption thereof, fill a prescription: the extract of medicine-food two-purpose: bark of eucommia 8g, rhizoma Gastrodiae 8g, red sage root 8g, Ligusticum wallichii 8g, root of herbaceous peony 7g, Radix et Rhizoma Gynurae divaricatae 7g, stem of noble dendrobium 12g, Cordyceps sinensis (aweto mycelium) 11g, Cordyceps militaris 11g, lucidum spore powder (broken wall) 7g, glossy ganoderma 7, Radix Astragali 7g, selfheal 6g, corn stigma 6g, Sessileflower Acanthopanax Bark 6g, Radix puerariae 6g, hawthorn 5g, peach kernel 5g, lophatherum gracile 5g, cornus officinalis sieb et zucc 5g, chrysanthemum 5g, cassia seed 5g, sealwort 5g, Radix Glycyrrhizae 4g, matrimony vine 4g, Poria cocos 4g, oyster 4g, earthworm albumen powder 4g, natto 4g, red yeast rice 3g, rape pollen 3g, CLA 3g, phosphatidylserine 3g, algae extrats 3g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

First will be to be the stem of noble dendrobium during making, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, the bark of eucommia, rhizoma Gastrodiae, the red sage root, Ligusticum wallichii, the root of herbaceous peony, Radix et Rhizoma Gynurae divaricatae, lucidum spore powder (broken wall), glossy ganoderma, the Radix Astragali, selfheal, corn stigma, Sessileflower Acanthopanax Bark, Radix puerariae, hawthorn, peach kernel, lophatherum gracile, cornus officinalis sieb et zucc, chrysanthemum, cassia seed, sealwort, Radix Glycyrrhizae, matrimony vine, Poria cocos, oyster, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, after soaking, Gorgon fruit adds cycloheptaamylose, after extracting by prehydrolysis SBE technology, and the spray-dried and flour of preparation, then add the small peptide that biological enzymolysis extracts, prebiotics, amino acid, earthworm albumen powder, natto, red yeast rice, rape pollen, CLA, phosphatidylserine, algae extrats, carbohydrate, after multivitamin and mineral matter are pulverized and mixed together, carry out pasteurization 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets the good production standard of < < special medicine purposes formula food > > requirement.

Embodiment bis-

The full nutrient formulation food of above-mentioned hypertension also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 13g, corn stigma 13g, Sessileflower Acanthopanax Bark 12g, Radix puerariae 12g, hawthorn 12g, peach kernel 11g, lophatherum gracile 11g, cornus officinalis sieb et zucc 10g, chrysanthemum 10g, cassia seed 10g, sealwort 9g, Radix Glycyrrhizae 9g, matrimony vine 9g, Poria cocos 9g, oyster 8g, earthworm albumen powder 8g, natto 7g, red yeast rice 7g, rape pollen 6g, CLA 6g, phosphatidylserine 4g, algae extrats 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

Embodiment tri-

The full nutrient formulation food of above-mentioned hypertension also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 13g, corn stigma 13g, Sessileflower Acanthopanax Bark 12g, Radix puerariae 12g, hawthorn 12g, peach kernel 11g, lophatherum gracile 11g, cornus officinalis sieb et zucc 10g, chrysanthemum 10g, cassia seed 10g, sealwort 9g, Radix Glycyrrhizae 9g, matrimony vine 9g, Poria cocos 9g, oyster 8g, earthworm albumen powder 8g, natto 7g, red yeast rice 7g, rape pollen 6g, CLA 6g, phosphatidylserine 4g, algae extrats 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, carbohydrate 150g, prebiotics 100g, several amino acids 100g.

The present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, mix with the Chinese medical extract after biological enzymolysis or the extraction of prehydrolysis SBE technology microencapsulation processing again, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and by gastric juice, arrive in enteron aisle and stop field planting smoothly by oral, the antihypertensive effect of product is compared with market like product significantly and improved.

Claims

1. the full nutrient formulation food of hypertension, its feature is characterized in that with the constitutive character in conjunction with hyperpietic, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, it is primary raw material that gold compatibility be take Chinese medical extract elite, multiple probio, the small peptide of 3 kinds of above medicine-food two-purposes, take the food that prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials make as auxiliary material;

Its preparation method is for first will be to be the stone stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, the bark of eucommia, rhizoma Gastrodiae, the red sage root, Ligusticum wallichii, the root of herbaceous peony, Radix et Rhizoma Gynurae divaricatae, lucidum spore powder (broken wall), glossy ganoderma, the Radix Astragali, selfheal, corn stigma, Sessileflower Acanthopanax Bark, Radix puerariae, hawthorn, peach kernel, lophatherum gracile, cornus officinalis sieb et zucc, chrysanthemum, cassia seed, sealwort, Radix Glycyrrhizae, matrimony vine, Poria cocos, oyster, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, after soaking, Gorgon fruit adds cycloheptaamylose, after extracting by prehydrolysis SBE technology, and the spray-dried and flour of preparation, then add the small peptide that biological enzymolysis extracts, prebiotics, amino acid, earthworm albumen powder, natto, red yeast rice, rape pollen, CLA, phosphatidylserine, algae extrats, carbohydrate, multivitamin and mineral matter carry out pasteurization 1 hour after mixing, and then add the Bifidobacterium after microencapsulation, lactobacillus, the various batchings that streptococcus thermophilus also adds appropriate carbohydrate mixing again mix the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets the good production standard of < < special medicine purposes formula food > > requirement.

2. the full nutrient formulation food formula of hypertension according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract and new resource food are: the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, the bark of eucommia, rhizoma Gastrodiae, the red sage root, Ligusticum wallichii, the root of herbaceous peony, Radix et Rhizoma Gynurae divaricatae, lucidum spore powder (broken wall), glossy ganoderma, the Radix Astragali, selfheal, corn stigma, Sessileflower Acanthopanax Bark, Radix puerariae, hawthorn, peach kernel, lophatherum gracile, cornus officinalis sieb et zucc, chrysanthemum, cassia seed, sealwort, Radix Glycyrrhizae, matrimony vine, Poria cocos, oyster, earthworm albumen powder, natto, red yeast rice, rape pollen, CLA, phosphatidylserine, algae extrats 3 kinds of above or all mixing wherein.

3. the full nutrient formulation food formula of hypertension according to claim 1, is characterised in that according to described formula and mixes and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food.

4. the full nutrient formulation food formula of hypertension according to claim 1, is characterized in that described small peptide is wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.

5. the full nutrient formulation food formula of hypertension according to claim 1, is characterized in that described prebiotics is. to external source probio, to have very strong field planting effect prebiotics be wherein several of extract, stachyose, yeast and common prebiotics of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke or all mix.

6. require the full nutrient formulation food formula of hypertension described in 1, it is characterized in that described amino acid is a kind of, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.

7. the full nutrient formulation food formula of hypertension according to claim 1, is characterized in that described carbohydrate is a kind of, several or all mixing wherein of glucose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen.

8. the full nutrient formulation food formula of hypertension according to claim 1, is characterized in that being dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, mix with the Chinese medical extract after biological enzymolysis or the extraction of prehydrolysis SBE technology microencapsulation processing again, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and by gastric juice, arrive in enteron aisle and stop field planting smoothly by oral, make product prevent and treat hypertension effect and compare significantly raising with market like product.

9. the full nutrient formulation food formula of hypertension according to claim 1, it is characterized in that described vitamin is vitamin A, vitamin D, vitamin E, vitamin K, vitamin C, Cobastab h vitamin B2, Cobastab " Cobastab, 2, wherein a kind of, several of nicotinic acid, folic acid, pantothenic acid, choline, biotin or all mix; Described mineral matter is a kind of, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum.