CN106480120B - L-甲硫氨酸和相关产物的生产方法 - Google Patents

L-甲硫氨酸和相关产物的生产方法 Download PDF

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CN106480120B
CN106480120B CN201610801257.6A CN201610801257A CN106480120B CN 106480120 B CN106480120 B CN 106480120B CN 201610801257 A CN201610801257 A CN 201610801257A CN 106480120 B CN106480120 B CN 106480120B
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methionine
optionally
acid
acetate
exemplary embodiments
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CN106480120A (zh
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洪淳源
黄仁奭
李相穆
李允宰
郑准泳
阿荣·伊亚尔
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CJ CheilJedang Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C05—FERTILISERS; MANUFACTURE THEREOF
    • C05C—NITROGENOUS FERTILISERS
    • C05C11/00—Other nitrogenous fertilisers
    • C—CHEMISTRY; METALLURGY
    • C05—FERTILISERS; MANUFACTURE THEREOF
    • C05C—NITROGENOUS FERTILISERS
    • C05C3/00—Fertilisers containing other salts of ammonia or ammonia itself, e.g. gas liquor
    • C—CHEMISTRY; METALLURGY
    • C05—FERTILISERS; MANUFACTURE THEREOF
    • C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
    • C05G3/00—Mixtures of one or more fertilisers with additives not having a specially fertilising activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54—Acetic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pest Control & Pesticides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Botany (AREA)
  • Fodder In General (AREA)
CN201610801257.6A 2010-12-29 2011-12-29 L-甲硫氨酸和相关产物的生产方法 Active CN106480120B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201061428171P 2010-12-29 2010-12-29
US61/428,171 2010-12-29
US201161562694P 2011-11-22 2011-11-22
US61/562,694 2011-11-22
PCT/KR2011/010288 WO2012091479A2 (en) 2010-12-29 2011-12-29 Methods for production of l-methionine and related products
CN201180067697.9A CN103476938B (zh) 2010-12-29 2011-12-29 L-甲硫氨酸和相关产物的生产方法

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EP (1) EP2658986B1 (enExample)
JP (2) JP6368488B2 (enExample)
KR (2) KR101500821B1 (enExample)
CN (2) CN106480120B (enExample)
BR (2) BR122019017369B1 (enExample)
MY (1) MY169343A (enExample)
RU (2) RU2673190C1 (enExample)
WO (1) WO2012091479A2 (enExample)

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US9260732B2 (en) * 2010-12-29 2016-02-16 Cj Cheiljedang Corp Methods for production of L-methionine and related products
EP2641898A1 (de) * 2012-03-20 2013-09-25 Evonik Industries AG Verfahren zur Herstellung von Methionin
CN104744326B (zh) * 2015-02-12 2016-08-10 山东新和成氨基酸有限公司 一种连续制备高堆积密度甲硫氨酸结晶的方法
KR20160111285A (ko) * 2015-03-16 2016-09-26 씨제이제일제당 (주) 사료 첨가제용 조성물 및 이를 포함하는 동물 사료 조성물
FR3041635B1 (fr) * 2015-09-30 2019-01-25 Arkema France Procede de production de mercaptans par hydrogenolyse enzymatique de disulfures
FR3041636B1 (fr) * 2015-09-30 2018-11-16 Arkema France Procede de production de mercaptans par hydrogenolyse enzymatique de disulfures a l'aide d'hydrogene
CN108473967B (zh) 2015-12-17 2022-03-29 赢创运营有限公司 基因修饰的产乙酸细胞
KR20180093981A (ko) * 2016-01-08 2018-08-22 에보니크 데구사 게엠베하 발효적 생산에 의해 l-메티오닌을 생산하는 방법
KR20190026851A (ko) 2016-07-08 2019-03-13 에보니크 데구사 게엠베하 당 포스포트랜스퍼라제 시스템 (pts)을 코딩하는 유전자를 포함하는 미생물에 의한 메티오닌 또는 그의 히드록시 유사체 형태의 발효적 생산을 위한 방법
JP2019523271A (ja) * 2016-07-27 2019-08-22 エボニック デグサ ゲーエムベーハーＥｖｏｎｉｋ Ｄｅｇｕｓｓａ ＧｍｂＨ Ｎ−アセチルホモセリン
CN106174596A (zh) * 2016-08-11 2016-12-07 塔城市星河生物工程有限责任公司 一种食用植物氨基酸干粉的生产方法
EP3330380A1 (en) 2016-12-05 2018-06-06 Evonik Degussa GmbH Process for producing l-methionine from methional
KR20180078621A (ko) * 2016-12-30 2018-07-10 씨제이제일제당 (주) 결정화 기술을 이용한 l-메티오닌 결정의 제조방법
FR3074174B1 (fr) 2017-11-30 2020-02-07 Afyren Procede de valorisation de sels de potassium coproduits de procedes de fermentation
WO2020101074A1 (ko) * 2018-11-15 2020-05-22 씨제이제일제당 (주) N-아세틸-l-트립토판을 유효성분으로 포함하는 젖소용 사료첨가제
CN109608372B (zh) * 2018-12-24 2021-05-11 天津大学 一种短棒状蛋氨酸晶体的多级连续结晶方法
WO2022078940A1 (en) * 2020-10-13 2022-04-21 Evonik Operations Gmbh D,l-methionine with an optimized particle size distribution
CN115124444B (zh) * 2022-06-09 2024-03-08 山东国邦药业有限公司 一种(2s,3r)-对甲砜基苯丝氨酸乙酯的制备方法
KR102898630B1 (ko) 2023-02-13 2025-12-11 씨제이제일제당 주식회사 아세트산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법
KR102816393B1 (ko) 2023-08-07 2025-06-02 정순원 커피 원두의 볶은 정도 측정용 트레이

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CN1751120A (zh) * 2003-02-18 2006-03-22 代谢开发公司 生产能产生或修饰代谢途径的进化微生物的方法
CN1894417A (zh) * 2003-12-18 2007-01-10 巴斯福股份公司 从发酵液中分离甲硫氨酸的方法
CN101356281A (zh) * 2006-07-28 2009-01-28 Cj第一制糖株式会社 生产l-蛋氨酸前体的微生物以及由l-蛋氨酸前体制备l-蛋氨酸和有机酸的方法
US20100041108A1 (en) * 1998-11-17 2010-02-18 Ajinomoto Co., Inc. Method for producing l-methionine by fermentation
CN101688190A (zh) * 2007-04-11 2010-03-31 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法

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US20100041108A1 (en) * 1998-11-17 2010-02-18 Ajinomoto Co., Inc. Method for producing l-methionine by fermentation
CN1751120A (zh) * 2003-02-18 2006-03-22 代谢开发公司 生产能产生或修饰代谢途径的进化微生物的方法
CN1894417A (zh) * 2003-12-18 2007-01-10 巴斯福股份公司 从发酵液中分离甲硫氨酸的方法
CN101356281A (zh) * 2006-07-28 2009-01-28 Cj第一制糖株式会社 生产l-蛋氨酸前体的微生物以及由l-蛋氨酸前体制备l-蛋氨酸和有机酸的方法
CN101688190A (zh) * 2007-04-11 2010-03-31 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法

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US9752167B2 (en) 2017-09-05
CN106480120A (zh) 2017-03-08
BR112013016810B1 (pt) 2020-12-29
EP2658986A4 (en) 2016-08-10
KR20140146638A (ko) 2014-12-26
BR112013016810A2 (pt) 2016-08-09
EP2658986B1 (en) 2020-10-28
WO2012091479A3 (en) 2012-10-04
JP6368488B2 (ja) 2018-08-01
CN103476938B (zh) 2016-10-12
US20120178966A1 (en) 2012-07-12
CN103476938A (zh) 2013-12-25
KR20120129994A (ko) 2012-11-28
JP2017123845A (ja) 2017-07-20
RU2673190C1 (ru) 2018-11-22
KR101500821B1 (ko) 2015-03-10
RU2013131758A (ru) 2015-02-10
MY169343A (en) 2019-03-21
JP2014501116A (ja) 2014-01-20
US20160108445A1 (en) 2016-04-21
RU2598276C2 (ru) 2016-09-20
BR122019017369B1 (pt) 2021-04-13
KR101543199B1 (ko) 2015-08-10
EP2658986A2 (en) 2013-11-06
WO2012091479A9 (en) 2012-11-15
JP6599375B2 (ja) 2019-10-30
US9260732B2 (en) 2016-02-16
WO2012091479A2 (en) 2012-07-05

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