JP2014501116A5 - - Google Patents
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- Publication number
- JP2014501116A5 JP2014501116A5 JP2013547352A JP2013547352A JP2014501116A5 JP 2014501116 A5 JP2014501116 A5 JP 2014501116A5 JP 2013547352 A JP2013547352 A JP 2013547352A JP 2013547352 A JP2013547352 A JP 2013547352A JP 2014501116 A5 JP2014501116 A5 JP 2014501116A5
- Authority
- JP
- Japan
- Prior art keywords
- methionine
- residual liquid
- acetate
- group
- oahs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 18
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 16
- 239000007788 liquid Substances 0.000 claims 14
- 229960004452 methionine Drugs 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 claims 11
- 229930195722 L-methionine Natural products 0.000 claims 11
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- FCXZBWSIAGGPCB-YFKPBYRVSA-N O-acetyl-L-homoserine Chemical compound CC(=O)OCC[C@H]([NH3+])C([O-])=O FCXZBWSIAGGPCB-YFKPBYRVSA-N 0.000 claims 8
- 238000000855 fermentation Methods 0.000 claims 7
- 230000004151 fermentation Effects 0.000 claims 7
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 6
- 238000002425 crystallisation Methods 0.000 claims 5
- 230000008025 crystallization Effects 0.000 claims 5
- 239000013078 crystal Substances 0.000 claims 4
- FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 229910021529 ammonia Inorganic materials 0.000 claims 3
- 150000003863 ammonium salts Chemical class 0.000 claims 3
- 239000002585 base Substances 0.000 claims 3
- 229930182817 methionine Natural products 0.000 claims 3
- 238000000926 separation method Methods 0.000 claims 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 claims 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- OKTJSMMVPCPJKN-IGMARMGPSA-N Carbon-12 Chemical compound [12C] OKTJSMMVPCPJKN-IGMARMGPSA-N 0.000 claims 2
- OKTJSMMVPCPJKN-NJFSPNSNSA-N Carbon-14 Chemical compound [14C] OKTJSMMVPCPJKN-NJFSPNSNSA-N 0.000 claims 2
- 229930182818 D-methionine Natural products 0.000 claims 2
- 150000001298 alcohols Chemical class 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims 2
- 235000011130 ammonium sulphate Nutrition 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000012535 impurity Substances 0.000 claims 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000003607 modifier Substances 0.000 claims 2
- 238000011084 recovery Methods 0.000 claims 2
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 claims 1
- 239000005695 Ammonium acetate Substances 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- 159000000021 acetate salts Chemical class 0.000 claims 1
- 238000007792 addition Methods 0.000 claims 1
- 229940043376 ammonium acetate Drugs 0.000 claims 1
- 235000019257 ammonium acetate Nutrition 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 159000000007 calcium salts Chemical class 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 1
- 150000001735 carboxylic acids Chemical class 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000004821 distillation Methods 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- 230000005484 gravity Effects 0.000 claims 1
- 229910001385 heavy metal Inorganic materials 0.000 claims 1
- 238000005342 ion exchange Methods 0.000 claims 1
- GJRQTCIYDGXPES-UHFFFAOYSA-N iso-butyl acetate Natural products CC(C)COC(C)=O GJRQTCIYDGXPES-UHFFFAOYSA-N 0.000 claims 1
- FGKJLKRYENPLQH-UHFFFAOYSA-M isocaproate Chemical compound CC(C)CCC([O-])=O FGKJLKRYENPLQH-UHFFFAOYSA-M 0.000 claims 1
- OQAGVSWESNCJJT-UHFFFAOYSA-N isovaleric acid methyl ester Natural products COC(=O)CC(C)C OQAGVSWESNCJJT-UHFFFAOYSA-N 0.000 claims 1
- 238000005374 membrane filtration Methods 0.000 claims 1
- 150000007524 organic acids Chemical class 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 238000010979 pH adjustment Methods 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061428171P | 2010-12-29 | 2010-12-29 | |
| US61/428,171 | 2010-12-29 | ||
| US201161562694P | 2011-11-22 | 2011-11-22 | |
| US61/562,694 | 2011-11-22 | ||
| PCT/KR2011/010288 WO2012091479A2 (en) | 2010-12-29 | 2011-12-29 | Methods for production of l-methionine and related products |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017007916A Division JP6599375B2 (ja) | 2010-12-29 | 2017-01-19 | Ｌ−メチオニン及び関連産物の生産方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501116A JP2014501116A (ja) | 2014-01-20 |
| JP2014501116A5 true JP2014501116A5 (enExample) | 2015-02-19 |
| JP6368488B2 JP6368488B2 (ja) | 2018-08-01 |
Family
ID=46383742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013547352A Active JP6368488B2 (ja) | 2010-12-29 | 2011-12-29 | Ｌ−メチオニン及び関連産物の生産方法 |
| JP2017007916A Active JP6599375B2 (ja) | 2010-12-29 | 2017-01-19 | Ｌ−メチオニン及び関連産物の生産方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017007916A Active JP6599375B2 (ja) | 2010-12-29 | 2017-01-19 | Ｌ−メチオニン及び関連産物の生産方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9260732B2 (enExample) |
| EP (1) | EP2658986B1 (enExample) |
| JP (2) | JP6368488B2 (enExample) |
| KR (2) | KR101543199B1 (enExample) |
| CN (2) | CN103476938B (enExample) |
| BR (2) | BR112013016810B1 (enExample) |
| MY (1) | MY169343A (enExample) |
| RU (2) | RU2673190C1 (enExample) |
| WO (1) | WO2012091479A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6368488B2 (ja) * | 2010-12-29 | 2018-08-01 | シージェイ チェイルジェダン コーポレーション | Ｌ−メチオニン及び関連産物の生産方法 |
| EP2641898A1 (de) * | 2012-03-20 | 2013-09-25 | Evonik Industries AG | Verfahren zur Herstellung von Methionin |
| CN104744326B (zh) * | 2015-02-12 | 2016-08-10 | 山东新和成氨基酸有限公司 | 一种连续制备高堆积密度甲硫氨酸结晶的方法 |
| KR20160111285A (ko) * | 2015-03-16 | 2016-09-26 | 씨제이제일제당 (주) | 사료 첨가제용 조성물 및 이를 포함하는 동물 사료 조성물 |
| FR3041636B1 (fr) * | 2015-09-30 | 2018-11-16 | Arkema France | Procede de production de mercaptans par hydrogenolyse enzymatique de disulfures a l'aide d'hydrogene |
| FR3041635B1 (fr) * | 2015-09-30 | 2019-01-25 | Arkema France | Procede de production de mercaptans par hydrogenolyse enzymatique de disulfures |
| ES2803208T3 (es) | 2015-12-17 | 2021-01-25 | Evonik Operations Gmbh | Una célula acetogénica genéticamente modificada |
| US20180355390A1 (en) * | 2016-01-08 | 2018-12-13 | Evonik Degussa Gmbh | Method to produce L-methionine by a fermentative production |
| EP3481851B1 (en) | 2016-07-08 | 2021-11-24 | Metabolic Explorer | Method for the fermentative production of molecules of interest by microorganisms comprising genes coding sugar phosphotransferase system (pts) |
| MY187786A (en) | 2016-07-27 | 2021-10-22 | Evonik Operations Gmbh | N-acetyl homoserine |
| CN106174596A (zh) * | 2016-08-11 | 2016-12-07 | 塔城市星河生物工程有限责任公司 | 一种食用植物氨基酸干粉的生产方法 |
| EP3330380A1 (en) | 2016-12-05 | 2018-06-06 | Evonik Degussa GmbH | Process for producing l-methionine from methional |
| KR20180078621A (ko) * | 2016-12-30 | 2018-07-10 | 씨제이제일제당 (주) | 결정화 기술을 이용한 l-메티오닌 결정의 제조방법 |
| FR3074174B1 (fr) | 2017-11-30 | 2020-02-07 | Afyren | Procede de valorisation de sels de potassium coproduits de procedes de fermentation |
| EP3845072B1 (en) * | 2018-11-15 | 2025-11-05 | CJ Cheiljedang Corporation | Feed supplement and feed for dairy cows comprising n-acetyl-l-tryptophan as effective component |
| CN109608372B (zh) * | 2018-12-24 | 2021-05-11 | 天津大学 | 一种短棒状蛋氨酸晶体的多级连续结晶方法 |
| WO2022078940A1 (en) * | 2020-10-13 | 2022-04-21 | Evonik Operations Gmbh | D,l-methionine with an optimized particle size distribution |
| CN115124444B (zh) * | 2022-06-09 | 2024-03-08 | 山东国邦药业有限公司 | 一种(2s,3r)-对甲砜基苯丝氨酸乙酯的制备方法 |
| KR102898630B1 (ko) | 2023-02-13 | 2025-12-11 | 씨제이제일제당 주식회사 | 아세트산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법 |
| KR102816393B1 (ko) | 2023-08-07 | 2025-06-02 | 정순원 | 커피 원두의 볶은 정도 측정용 트레이 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2867655A (en) * | 1957-02-20 | 1959-01-06 | Donald F Othmer | Process for recovering volatile aliphatic acids |
| JPS4324890B1 (enExample) * | 1966-08-25 | 1968-10-28 | ||
| NL6815005A (enExample) * | 1968-10-19 | 1970-04-21 | ||
| JPS5824890B2 (ja) | 1978-05-31 | 1983-05-24 | 松下電工株式会社 | 消弧装置 |
| US5168055A (en) * | 1986-06-11 | 1992-12-01 | Rathin Datta | Fermentation and purification process for succinic acid |
| US5068188A (en) * | 1989-06-20 | 1991-11-26 | Northeastern University | Process for manufacture of alkaline earth acetates |
| JPH04244056A (ja) * | 1991-01-31 | 1992-09-01 | Sumitomo Chem Co Ltd | メチオニンの製造方法 |
| JP4110641B2 (ja) * | 1998-11-17 | 2008-07-02 | 味の素株式会社 | 発酵法によるｌ−メチオニンの製造法 |
| RU2209248C2 (ru) * | 2001-06-26 | 2003-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-метионина, штамм бактерии escherichia coli вкпм в-8125 - продуцент l-метионина |
| WO2003045904A1 (en) * | 2001-11-29 | 2003-06-05 | Nippon Soda Co.,Ltd. | Process for production of methionine |
| JP2006517796A (ja) * | 2003-02-18 | 2006-08-03 | メタボリック エクスプローラー | 代謝経路の生成または改変を可能とする進化した微生物の生産方法 |
| FR2851256A1 (fr) * | 2003-02-18 | 2004-08-20 | Metabolic Explorer Sa | Procede de criblage et d'evolution dirigee de souches produisant de la methionine par nouvelle voie metabolique |
| EP1656454A4 (en) * | 2003-07-08 | 2011-06-22 | Novus Int Inc | PROCESS FOR METHIONINAL RECOVERY |
| DE10359668A1 (de) * | 2003-12-18 | 2005-07-14 | Basf Ag | Verfahren zur Herstellung von Methionin |
| BRPI0613662A2 (pt) * | 2005-07-18 | 2017-05-09 | Basf Ag | microorganismo recombinante, e, método para produzir metionina |
| KR100905381B1 (ko) * | 2006-07-28 | 2009-06-30 | 씨제이제일제당 (주) | Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법 |
| KR100864673B1 (ko) * | 2006-11-27 | 2008-10-23 | 씨제이제일제당 (주) | 비용매를 이용하여 쓰레오닌 생산 미생물의 발효액으로부터쓰레오닌을 회수하는 방법 |
| DE102006061479A1 (de) * | 2006-12-23 | 2008-06-26 | Evonik Degussa Gmbh | Verfahren zur Herstellung verschiedener, eine Zielsubstanz enthaltender Produkte |
| KR101140906B1 (ko) * | 2007-04-11 | 2012-07-13 | 씨제이제일제당 (주) | 조성물 및 메티오닌 생산방법 |
| KR101048593B1 (ko) * | 2009-02-27 | 2011-07-12 | 씨제이제일제당 (주) | 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법 |
| KR101164711B1 (ko) * | 2009-02-27 | 2012-07-11 | 씨제이제일제당 (주) | 미네랄 첨가와 산처리를 이용하여 메치오닌의 용해도를 증가시키는 방법 |
| FR2951195B1 (fr) * | 2009-10-14 | 2014-01-31 | Roquette Freres | Composition riche en methionine destinee a l'alimentation animale |
| JP6368488B2 (ja) * | 2010-12-29 | 2018-08-01 | シージェイ チェイルジェダン コーポレーション | Ｌ−メチオニン及び関連産物の生産方法 |
-
2011
- 2011-12-29 JP JP2013547352A patent/JP6368488B2/ja active Active
- 2011-12-29 RU RU2016135032A patent/RU2673190C1/ru active
- 2011-12-29 US US13/339,441 patent/US9260732B2/en active Active
- 2011-12-29 KR KR1020147030633A patent/KR101543199B1/ko active Active
- 2011-12-29 BR BR112013016810-2A patent/BR112013016810B1/pt active IP Right Grant
- 2011-12-29 KR KR1020127024649A patent/KR101500821B1/ko active Active
- 2011-12-29 RU RU2013131758/10A patent/RU2598276C2/ru active
- 2011-12-29 BR BR122019017369-9A patent/BR122019017369B1/pt active IP Right Grant
- 2011-12-29 WO PCT/KR2011/010288 patent/WO2012091479A2/en not_active Ceased
- 2011-12-29 MY MYPI2013002486A patent/MY169343A/en unknown
- 2011-12-29 CN CN201180067697.9A patent/CN103476938B/zh active Active
- 2011-12-29 EP EP11852758.9A patent/EP2658986B1/en active Active
- 2011-12-29 CN CN201610801257.6A patent/CN106480120B/zh active Active
-
2015
- 2015-12-29 US US14/982,108 patent/US9752167B2/en active Active
-
2017
- 2017-01-19 JP JP2017007916A patent/JP6599375B2/ja active Active
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