CN106456537A - 用于治疗眼睛的组合物 - Google Patents

用于治疗眼睛的组合物 Download PDF

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Publication number
CN106456537A
CN106456537A CN201580026099.5A CN201580026099A CN106456537A CN 106456537 A CN106456537 A CN 106456537A CN 201580026099 A CN201580026099 A CN 201580026099A CN 106456537 A CN106456537 A CN 106456537A
Authority
CN
China
Prior art keywords
composition
acid
tetrahydromethylpyrimidinecarboxylic
cellulose
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580026099.5A
Other languages
English (en)
Chinese (zh)
Inventor
A·比尔施泰因
H-J·加拉
M·德维韦迪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bitop AG
Original Assignee
Bitop AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53433159&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106456537(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bitop AG filed Critical Bitop AG
Publication of CN106456537A publication Critical patent/CN106456537A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201580026099.5A 2014-05-22 2015-05-22 用于治疗眼睛的组合物 Pending CN106456537A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102014007423.4A DE102014007423A1 (de) 2014-05-22 2014-05-22 Zusammensetzung zur Behandlung des Auges
DE102014007423.4 2014-05-22
PCT/EP2015/061434 WO2015177353A1 (de) 2014-05-22 2015-05-22 Zusammensetzung zur behandlung des auges

Publications (1)

Publication Number Publication Date
CN106456537A true CN106456537A (zh) 2017-02-22

Family

ID=53433159

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580026099.5A Pending CN106456537A (zh) 2014-05-22 2015-05-22 用于治疗眼睛的组合物

Country Status (10)

Country Link
US (3) US20170173012A1 (enExample)
EP (2) EP3977998A1 (enExample)
JP (1) JP2017516770A (enExample)
CN (1) CN106456537A (enExample)
CA (1) CA2949203C (enExample)
DE (1) DE102014007423A1 (enExample)
ES (1) ES2906431T3 (enExample)
PL (1) PL3145511T3 (enExample)
RU (1) RU2016150412A (enExample)
WO (1) WO2015177353A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467349A (zh) * 2020-05-14 2020-07-31 华熙生物科技股份有限公司 人工泪液及其制备方法
CN111991415A (zh) * 2020-09-11 2020-11-27 华熙生物科技股份有限公司 一种眼部护理组合物及其制备方法和用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102016203696A1 (de) * 2016-03-07 2017-09-07 Ursapharm Arzneimittel Gmbh Ophthalmologische Zusammensetzung
DE102016204472A1 (de) * 2016-03-17 2017-09-21 Ursapharm Arzneimittel Gmbh Kit zur kosmetischen Behandlung des Auges und der Haut und Kosmetikum zur Anwendung am Auge und auf der Haut
EP3827818A1 (en) * 2019-11-26 2021-06-02 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic composition
US12012238B2 (en) 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
CN116139067B (zh) * 2021-11-22 2024-03-22 华熙生物科技股份有限公司 透明质酸锌形成凝胶的方法及含有透明质酸锌的滴眼凝胶及其制备

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101491525A (zh) * 2009-03-03 2009-07-29 山东大学 四氢嘧啶在制备治疗干眼症药物中的应用
WO2013034299A1 (de) * 2011-09-09 2013-03-14 Bitop Ag Therapeutische anwendungen von ectoin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
US5698533A (en) * 1994-07-26 1997-12-16 Kang; Meng-Che Ophthalmic pharmaceutical composition
JP3624418B2 (ja) * 1994-12-19 2005-03-02 大正製薬株式会社 リポソーム点眼液
JPH0977656A (ja) * 1995-09-14 1997-03-25 Toshihiro Handa 点眼用エアゾル組成物
GB9716376D0 (en) * 1997-08-01 1997-10-08 Isis Innovation Artificial tear formulation
DE10006578C2 (de) 2000-02-14 2002-10-31 Bitop Ag Verwendung von kompatiblen Soluten als Inhibitoren des enzymatischen Abbaus von makromolekularen Biopolymeren
DE10330243A1 (de) 2003-07-03 2005-01-20 bitop Aktiengesellschaft für biotechnische Optimierung Verwendung von aus extremophilen Bakterien gewonnenen Osmolyten zur Herstellung von Arzneimitteln zur äusserlichen Behandlung der Neurodermitis
US20080132444A1 (en) * 2004-10-09 2008-06-05 Xiaoling Li Ocular Agent Delivery Systems
DE102006056766A1 (de) 2006-12-01 2008-06-05 Bitop Ag Verwendung von kompatiblen Soluten
CN101605531B (zh) * 2007-02-09 2012-10-10 爱尔康公司 含有三种聚合物的协同组合的眼用组合物
DE102007052380A1 (de) * 2007-10-31 2009-05-07 Bitop Ag Osmolythaltige Zubereitungen zur Anwendung bei trockenen Schleimhäuten
ES2356883B1 (es) * 2008-07-24 2012-02-22 Bcn Peptides, S.A. Composición para el tratamiento del dolor y/o la inflamación.
EP2823814A1 (en) * 2009-06-10 2015-01-14 Mitotech SA Pharmaceutical composition for use in medical and veterinary ophthalmology
US20110300097A1 (en) * 2010-06-04 2011-12-08 Al-Qahtani Ahmed H Method And Composition For The Treatment Of Moderate To Severe Keratoconjunctivitis Sicca

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101491525A (zh) * 2009-03-03 2009-07-29 山东大学 四氢嘧啶在制备治疗干眼症药物中的应用
WO2013034299A1 (de) * 2011-09-09 2013-03-14 Bitop Ag Therapeutische anwendungen von ectoin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GEBRAUCHSANWEISUNG: "HYLO-PROTECT", 《WWW.PREISAPO.DE/IMAGES/PRODUCTS/OSKAR/BEIPACKZETTEL/09715226.PDF》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467349A (zh) * 2020-05-14 2020-07-31 华熙生物科技股份有限公司 人工泪液及其制备方法
CN111991415A (zh) * 2020-09-11 2020-11-27 华熙生物科技股份有限公司 一种眼部护理组合物及其制备方法和用途
CN111991415B (zh) * 2020-09-11 2022-03-01 华熙生物科技股份有限公司 一种眼部护理组合物及其制备方法和用途

Also Published As

Publication number Publication date
WO2015177353A1 (de) 2015-11-26
EP3977998A1 (de) 2022-04-06
CA2949203A1 (en) 2015-11-26
EP3145511A1 (de) 2017-03-29
DE102014007423A1 (de) 2015-11-26
RU2016150412A3 (enExample) 2019-01-17
JP2017516770A (ja) 2017-06-22
US20250195515A1 (en) 2025-06-19
CA2949203C (en) 2023-10-31
ES2906431T3 (es) 2022-04-18
PL3145511T3 (pl) 2022-05-02
RU2016150412A (ru) 2018-06-25
US20220133719A1 (en) 2022-05-05
US20170173012A1 (en) 2017-06-22
EP3145511B1 (de) 2022-01-05

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SE01 Entry into force of request for substantive examination
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WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170222

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