CA2949203C - Composition for treating the eye - Google Patents

Composition for treating the eye Download PDF

Info

Publication number
CA2949203C
CA2949203C CA2949203A CA2949203A CA2949203C CA 2949203 C CA2949203 C CA 2949203C CA 2949203 A CA2949203 A CA 2949203A CA 2949203 A CA2949203 A CA 2949203A CA 2949203 C CA2949203 C CA 2949203C
Authority
CA
Canada
Prior art keywords
composition
ectoine
use according
hydroxyectoine
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2949203A
Other languages
English (en)
French (fr)
Other versions
CA2949203A1 (en
Inventor
Andreas Bilstein
Hans-Joachim Galla
Mridula DWIVEDI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bitop AG
Original Assignee
Bitop AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53433159&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2949203(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bitop AG filed Critical Bitop AG
Publication of CA2949203A1 publication Critical patent/CA2949203A1/en
Application granted granted Critical
Publication of CA2949203C publication Critical patent/CA2949203C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2949203A 2014-05-22 2015-05-22 Composition for treating the eye Active CA2949203C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102014007423.4A DE102014007423A1 (de) 2014-05-22 2014-05-22 Zusammensetzung zur Behandlung des Auges
DE102014007423.4 2014-05-22
PCT/EP2015/061434 WO2015177353A1 (de) 2014-05-22 2015-05-22 Zusammensetzung zur behandlung des auges

Publications (2)

Publication Number Publication Date
CA2949203A1 CA2949203A1 (en) 2015-11-26
CA2949203C true CA2949203C (en) 2023-10-31

Family

ID=53433159

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2949203A Active CA2949203C (en) 2014-05-22 2015-05-22 Composition for treating the eye

Country Status (10)

Country Link
US (3) US20170173012A1 (enExample)
EP (2) EP3977998A1 (enExample)
JP (1) JP2017516770A (enExample)
CN (1) CN106456537A (enExample)
CA (1) CA2949203C (enExample)
DE (1) DE102014007423A1 (enExample)
ES (1) ES2906431T3 (enExample)
PL (1) PL3145511T3 (enExample)
RU (1) RU2016150412A (enExample)
WO (1) WO2015177353A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102016203696A1 (de) * 2016-03-07 2017-09-07 Ursapharm Arzneimittel Gmbh Ophthalmologische Zusammensetzung
DE102016204472A1 (de) * 2016-03-17 2017-09-21 Ursapharm Arzneimittel Gmbh Kit zur kosmetischen Behandlung des Auges und der Haut und Kosmetikum zur Anwendung am Auge und auf der Haut
EP3827818A1 (en) * 2019-11-26 2021-06-02 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic composition
CN111467349B (zh) * 2020-05-14 2021-06-01 华熙生物科技股份有限公司 人工泪液及其制备方法
CN111991415B (zh) * 2020-09-11 2022-03-01 华熙生物科技股份有限公司 一种眼部护理组合物及其制备方法和用途
US12012238B2 (en) 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
CN116139067B (zh) * 2021-11-22 2024-03-22 华熙生物科技股份有限公司 透明质酸锌形成凝胶的方法及含有透明质酸锌的滴眼凝胶及其制备

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
US5698533A (en) * 1994-07-26 1997-12-16 Kang; Meng-Che Ophthalmic pharmaceutical composition
JP3624418B2 (ja) * 1994-12-19 2005-03-02 大正製薬株式会社 リポソーム点眼液
JPH0977656A (ja) * 1995-09-14 1997-03-25 Toshihiro Handa 点眼用エアゾル組成物
GB9716376D0 (en) * 1997-08-01 1997-10-08 Isis Innovation Artificial tear formulation
DE10006578C2 (de) 2000-02-14 2002-10-31 Bitop Ag Verwendung von kompatiblen Soluten als Inhibitoren des enzymatischen Abbaus von makromolekularen Biopolymeren
DE10330243A1 (de) 2003-07-03 2005-01-20 bitop Aktiengesellschaft für biotechnische Optimierung Verwendung von aus extremophilen Bakterien gewonnenen Osmolyten zur Herstellung von Arzneimitteln zur äusserlichen Behandlung der Neurodermitis
US20080132444A1 (en) * 2004-10-09 2008-06-05 Xiaoling Li Ocular Agent Delivery Systems
DE102006056766A1 (de) 2006-12-01 2008-06-05 Bitop Ag Verwendung von kompatiblen Soluten
CN101605531B (zh) * 2007-02-09 2012-10-10 爱尔康公司 含有三种聚合物的协同组合的眼用组合物
DE102007052380A1 (de) * 2007-10-31 2009-05-07 Bitop Ag Osmolythaltige Zubereitungen zur Anwendung bei trockenen Schleimhäuten
ES2356883B1 (es) * 2008-07-24 2012-02-22 Bcn Peptides, S.A. Composición para el tratamiento del dolor y/o la inflamación.
CN101491525A (zh) * 2009-03-03 2009-07-29 山东大学 四氢嘧啶在制备治疗干眼症药物中的应用
EP2823814A1 (en) * 2009-06-10 2015-01-14 Mitotech SA Pharmaceutical composition for use in medical and veterinary ophthalmology
US20110300097A1 (en) * 2010-06-04 2011-12-08 Al-Qahtani Ahmed H Method And Composition For The Treatment Of Moderate To Severe Keratoconjunctivitis Sicca
DE102011113059A1 (de) * 2011-09-09 2013-03-14 Bitop Ag Therapeutische Anwendungen von Ectoin

Also Published As

Publication number Publication date
WO2015177353A1 (de) 2015-11-26
EP3977998A1 (de) 2022-04-06
CA2949203A1 (en) 2015-11-26
EP3145511A1 (de) 2017-03-29
DE102014007423A1 (de) 2015-11-26
RU2016150412A3 (enExample) 2019-01-17
JP2017516770A (ja) 2017-06-22
US20250195515A1 (en) 2025-06-19
ES2906431T3 (es) 2022-04-18
PL3145511T3 (pl) 2022-05-02
RU2016150412A (ru) 2018-06-25
US20220133719A1 (en) 2022-05-05
US20170173012A1 (en) 2017-06-22
EP3145511B1 (de) 2022-01-05
CN106456537A (zh) 2017-02-22

Similar Documents

Publication Publication Date Title
US20250195515A1 (en) Composition for treating the eye
JP7224095B2 (ja) 眼科用組成物
JP5722802B2 (ja) プロスタグランジンを含有するアニオン性水中油型エマルジョンおよびその使用
SK4602001A3 (en) Ophthalmological compositions
US20070265353A1 (en) Eye Drops for the Treatment of Dry Eye
CN107205929B (zh) 多泡沫体及其眼睑施用
CN102421425A (zh) 用于治疗青光眼的不含磷酸盐的药物组合物
JP5722803B2 (ja) プロスタグランジンを含有するカチオン性水中油型エマルジョンおよびその使用
US20230149337A1 (en) Ophthalmic formulation and its use
EP4302767B1 (en) Ophthalmic composition comprising eriocitrin for treating dry eye syndrome
CA3190642A1 (en) Ophthalmic compositions for delivering meibum-like materials
CA2567418C (en) Viscous agent for ophthalmic use
JP2003267892A (ja) 熱ゲル化人工涙液
JP6166341B2 (ja) シクロスポリンａに基づく水性点眼溶液
WO2010148352A1 (en) Time-release and micro-dose formulations for topical application of estrogen and estrogen analogs or other estrogen receptor modulators in the treatment of dry eye syndrome, and methods of preparation and application
JP2006089460A (ja) 眼科用粘稠化剤
WO2023152644A1 (en) Pharmaceutical composition of lifitegrast and loteprednol etabonate
DE202014011522U1 (de) Zusammensetzung zur Behandlung des Auges

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224

EEER Examination request

Effective date: 20200224