CN106334017A - Chinese herbal medicine preparation for preventing skin fester of offshore cage culture fugu rubripes - Google Patents

Chinese herbal medicine preparation for preventing skin fester of offshore cage culture fugu rubripes Download PDF

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CN106334017A
CN106334017A CN201610962469.2A CN201610962469A CN106334017A CN 106334017 A CN106334017 A CN 106334017A CN 201610962469 A CN201610962469 A CN 201610962469A CN 106334017 A CN106334017 A CN 106334017A
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王培亮
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Weihai Hongrun Ocean Technology Co Ltd
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Weihai Hongrun Ocean Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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Abstract

The invention discloses a Chinese herbal medicine preparation for preventing skin fester of offshore cage culture fugu rubripes. The Chinese herbal medicine preparation is prepared from, by weight parts, 12-22 parts of herba artemisiae scopariae, 16-20 parts of Chinese thorowax root, 12-18 parts of sophora flavescens, 8-12 parts of coptidis rhizoma, 12-18 parts of gardenia jasminoides, 12-18 parts of polygonum cuspidatum, 2-6 parts of achyranthes bidentata, 8-11 parts of honeysuckle and 2-6 parts of gallnut. Conventional traditional Chinese medicines are reasonably composited, effects of antibiosis and antiphlogosis and immunity enhancement are very remarkable, and the effective therapeutic medicine for treating skin fester of offshore cage culture fugu rubripes is provided for the aquaculture industry. The Chinese herbal medicine preparation has the advantages of taking effect quickly, being real in curative effect and free of medicinal residue and having no toxic or side effect. By applying the Chinese herbal medicine preparation, the skin fester of offshore cage culture fugu rubripes can be effectively controlled, and the skin fester morbidity and mortality are reduced.

Description

A kind of Chinese herbal medicine for preventing and treating coastal waters cage culture red fin east Disease of skin fester Preparation
Technical field
The invention belongs to fishery practical technique field, specifically, it is used for preventing and treating coastal waters cage culture particularly to one kind Chinese herbal and crude drugs preparations of red fin east Disease of skin fester and preparation method thereof.
Background technology
The skin in coastal waters cage culture red fin east includes epidermis and corium two-layer, and also contains a kind of special gland Body, can secret out of substantial amounts of mucus, make skin be rich in mucosity, also can form effective physical protection screen on fish body surface simultaneously Barrier, protects fish body from the invasion and attack of pathogenic microorganism.Once coastal waters cage culture red fin east skin sustains damage, easy Bacterial infection and produce death.Exanthemv is coastal waters cage culture red fin east skin disease more typically, is typically due to Parasite is parasitic or fish body is subject to the infection such as mechanical injuries secondary bacterial, fungi to cause the inflammation of skin histology, and affected area continues And downright bad, tissue loss forms defect, and erosion, deep is ulcer to shallow defect.The red fin of coastal waters cage culture can be caused at present The bacterium majority of east exanthemv belongs to Gram-negative bacteria, mainly have pseudomonad, Aeromonas, tarda, Vibrios etc..After coastal waters cage culture red fin east body surface festers, basis of microscopic observation, it is possible to find infection fish body table muscle Necrotic fibres, dissolving, muscle fibre interstitial is broadening to some extent, oedema occurs, simultaneously also with lymphocyte and monocyte Infiltration Deng inflammatory cell.This disease is often concurrent with saprolegniasis.In low temperature rainy season, position of festering is easy to long water mold.Rotten Afterbody continues development and then may result in bacterial septicemia, and each internal organs all may occur in which different degrees of pathology.
The Disease of skin fester in coastal waters cage culture red fin east, all can occur throughout the year, and treats difficulty greatly, for The preventing and treating of this disease must adhere to the principle of " putting prevention first, anti-overweighting is controlled ".If fish body table festers, treat such disease not Pathogenic bacteria in water body only to be killed, more important point is the bacterium killed at exanthemv, takes antibacterials orally clear simultaneously Except internal pathogenic bacteria.
How to be treated using western medicine antibiotics at this stage, although aquatic medicine controls relatively strictly, western medicine antibiotics are indiscriminate With situation still extremely serious so that coastal waters cage culture red fin east treatment difficulty increase, medicament residue problem is increasingly Weight, causes seriously to threaten to food-safety problem.China's natural resources of Chinese medicinal materials enriches, by rationally being screened and group to traditional Chinese medicine Side, first-selected as preventing and treating coastal waters cage culture red fin east Disease of skin fester, will have very important production practices meaning.
Chinese herbal medicine belongs to natural drug, in application and the research of China, has accumulated rich experience.Using Chinese herbal medicine Preventing and treating coastal waters cage culture red fin east Disease of skin fester is increasingly subject to attention and the favor of people, is more and more extensively connect It is subject to, be that the mechanism of action unique with it, the mode of action and advantage are inseparable, put it briefly, herbal control disease has tune Whole effect, strengthening vital QI to eliminate pathogenic factors, have no drug resistance and the incomparable feature of other medicines and the advantage such as nuisanceless, effect is good, and There is not the residue problem of antibiotic medicine, highly beneficial to the animal husbandry products export of China.In addition, Chinese herbal medicine also has price Cheaply, wide material sources, the advantages of easy to use, are one of developing direction of fish medicine from now on.
Content of the invention
It is an object of the invention to provide a kind of for preventing and treating in the Disease of skin fester of coastal waters cage culture red fin east Herbal medicinal product.
The object of the present invention is achieved like this:
A kind of Chinese herbal and crude drugs preparations for preventing and treating coastal waters cage culture red fin east Disease of skin fester, by following weight portion Chinese medicine be prepared from: oriental wormwood 16-22 part, radix bupleuri 16-20 part, kuh-seng 12-18, coptis 8-12 part, mountain Cape jasmine 12-18 part, tiger Cane 12-18 part, root of bidentate achyranthes 2-6 part, honeysuckle 8-11 part, Chinese gall 2-6 part.
Preferably, the described Chinese herbal and crude drugs preparations for preventing and treating coastal waters cage culture red fin east Disease of skin fester, by The Chinese medicine of following weight portion is prepared from: 18 parts of oriental wormwood, 18 parts of radix bupleuri, kuh-seng 16,10 parts of the coptis, 16 parts of mountain Cape jasmine, giant knotweed 14 Part, 4 parts of the root of bidentate achyranthes, 9 parts of honeysuckle, 4 parts of Chinese gall.
It is further preferred that the described Chinese herbal medicine system for preventing and treating coastal waters cage culture red fin east Disease of skin fester Agent is granule.
The preparation method of the Chinese herbal and crude drugs preparations that above-mentioned each Chinese medicine preparation cost is invented, comprises the steps:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh the above-mentioned Chinese medicine cleaning up by recipe quantity, pulverize, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
The consumption of above-mentioned preventing and treating coastal waters cage culture red fin east Disease of skin fester Chinese herbal granules is by 50-80g/ The ratio of 100kg body weight mixes pharmaceutical chemistry, allows coastal waters cage culture red fin east to be administered orally, and being used in conjunction 5-7 days is a course for the treatment of.
The present inventor prevents and treats coastal waters cage culture red fin east Disease of skin fester with Chinese herbal and crude drugs preparations, from our experiment Result is seen, application the present invention Chinese herbal and crude drugs preparations can effective control coastal waters cage culture red fin east Disease of skin fester, reduce The M & M of coastal waters cage culture red fin east Disease of skin fester, but also do not produce drug resistance.The present invention will Traditional Chinese medicine reasonable formula, anti-inflammation, strengthen immunity effect extremely notable, be that culture fishery provides a kind of coastal waters The effectively treatment medicine of cage culture red fin east Disease of skin fester, has instant effect, curative effect really, no drug residue, no any The feature of toxic and side effect;Its preparation method is simple, the needs of suitable scale industrial production.
Specific embodiment
Further illustrate the present invention below by embodiment.Embodiments of the invention are only used for the present invention is described, and It is not limitation of the present invention, under the concept thereof of the present invention, the present invention is broadly fallen into the simple modifications of preparation method of the present invention Claimed scope.With reference to specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese herbal granules of preventing and treating coastal waters cage culture red fin east Disease of skin fester, by oriental wormwood, radix bupleuri, hardship Ginseng, the coptis, mountain Cape jasmine, giant knotweed, the root of bidentate achyranthes, honeysuckle, Chinese gall composition, wherein, oriental wormwood 18kg, radix bupleuri 18kg, kuh-seng 16kg, the coptis 10kg, mountain Cape jasmine 16kg, giant knotweed 14kg, root of bidentate achyranthes 4kg, honeysuckle 9kg, Chinese gall 4kg.
The preparation method of the Chinese herbal granules of above-mentioned preventing and treating coastal waters cage culture red fin east Disease of skin fester, concrete system Standby step is as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh clear oriental wormwood 18kg, radix bupleuri 18kg, kuh-seng 16kg, coptis 10kg, mountain Cape jasmine 16kg, giant knotweed 14kg, ox Knee 4kg, honeysuckle 9kg, Chinese gall 4kg are raw material, and wash clean Chinese medicine is pulverized, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
Embodiment 2
A kind of Chinese herbal granules of preventing and treating coastal waters cage culture red fin east Disease of skin fester, by oriental wormwood, radix bupleuri, hardship Ginseng, the coptis, mountain Cape jasmine, giant knotweed, the root of bidentate achyranthes, honeysuckle, Chinese gall composition, wherein, oriental wormwood 19kg, radix bupleuri 17kg, kuh-seng 15kg, the coptis 9kg, mountain Cape jasmine 14kg, giant knotweed 13kg, root of bidentate achyranthes 3kg, honeysuckle 10kg, Chinese gall 5kg.
The preparation method of the Chinese herbal granules of above-mentioned preventing and treating coastal waters cage culture red fin east Disease of skin fester, concrete system Standby step is as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh oriental wormwood 19kg, radix bupleuri 17kg, kuh-seng 15kg, coptis 9kg, mountain Cape jasmine 14kg, giant knotweed 13kg, the root of bidentate achyranthes 3kg, honeysuckle 10kg, Chinese gall 5kg are raw material, and wash clean Chinese medicine is pulverized, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
Embodiment 3
A kind of Chinese herbal granules of preventing and treating coastal waters cage culture red fin east Disease of skin fester, by oriental wormwood, radix bupleuri, hardship Ginseng, the coptis, mountain Cape jasmine, giant knotweed, the root of bidentate achyranthes, honeysuckle, Chinese gall composition, wherein, oriental wormwood 20kg, radix bupleuri 20kg, kuh-seng 18kg, the coptis 12kg, mountain Cape jasmine 18kg, giant knotweed 18kg, root of bidentate achyranthes 6kg, honeysuckle 11kg, Chinese gall 6kg.
The preparation method of the Chinese herbal granules of above-mentioned preventing and treating coastal waters cage culture red fin east Disease of skin fester, concrete system Standby step is as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh oriental wormwood 19kg, radix bupleuri 17kg, kuh-seng 15kg, coptis 9kg, mountain Cape jasmine 14kg, giant knotweed 13kg, the root of bidentate achyranthes 3kg, honeysuckle 10kg, Chinese gall 5kg are raw material, and wash clean Chinese medicine is pulverized, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
Embodiment 4 clinical testing
The consumption of the Chinese herbal granules of above-mentioned preventing and treating coastal waters cage culture red fin east Disease of skin fester is by 60g/ The ratio of 100kg body weight mixes pharmaceutical chemistry, is administered orally, and being used in conjunction 5 days is a course for the treatment of.After oral, treatment disease is reached by intestinal absorption Purpose.
On June 28th, 2013, the coastal waters that Shandong Province Rongcheng area certain coastal waters cage culture red fin east raiser raises Fall ill in cage culture red fin east, clinical symptoms: ill coastal waters cage culture Takifugu rubripes caudal peduncle portion, trunk or Skin of head festers, and necrosis comes off, and severe patient festers and is deep into muscle layer, festers in some disease fish kiss ends.It is that typical case bursts after diagnosing Rotten disease.Then, after using Chinese herbal granules treatment, medication 2 days described in the embodiment of the present invention 2, the state of an illness is clearly better, body color change Substantially, the death rate reduces by sky, and after 5 days, the death rate is 0, is almost recovered.
Inventor, with Chinese herbal and crude drugs preparations preventing and treating coastal waters cage culture red fin east Disease of skin fester, ties from our experiment Fruit sees, no matter being prevention, or treatment, evident in efficacy, but also do not produce drug resistance, promoting through test of many times and small area should With achieving good effect, so that fishing ground economic benefit is significantly improved.

Claims (3)

1. a kind of Chinese herbal and crude drugs preparations for preventing and treating coastal waters cage culture red fin east Disease of skin fester it is characterised in that: by The Chinese medicine of following weight portion is prepared from: oriental wormwood 12-22 part, radix bupleuri 16-20 part, kuh-seng 12-18, coptis 8-12 part, mountain Cape jasmine 12-18 part, giant knotweed 12-18 part, root of bidentate achyranthes 2-6 part, honeysuckle 8-11 part, Chinese gall 2-6 part.
2. the Chinese herbal medicine system for preventing and treating coastal waters cage culture red fin east Disease of skin fester according to claim 1 Agent it is characterised in that: be prepared from by the Chinese medicine of following weight portion: 18 parts of oriental wormwood, 18 parts of radix bupleuri, kuh-seng 16,10 parts of the coptis, 16 parts of mountain Cape jasmine, 14 parts of giant knotweed, 4 parts of the root of bidentate achyranthes, 9 parts of honeysuckle, 4 parts of Chinese gall.
3. the Chinese herbal medicine for preventing and treating coastal waters cage culture red fin east Disease of skin fester according to claim 1 and 2 Preparation it is characterised in that: it be granule.
CN201610962469.2A 2016-11-04 2016-11-04 Chinese herbal medicine preparation for preventing skin fester of offshore cage culture fugu rubripes Withdrawn CN106334017A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971132A (en) * 2015-07-16 2015-10-14 威海虹润海洋科技有限公司 Traditional Chinese medicine preparation for preventing and treating skin ulcer disease of octopus variabilis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971132A (en) * 2015-07-16 2015-10-14 威海虹润海洋科技有限公司 Traditional Chinese medicine preparation for preventing and treating skin ulcer disease of octopus variabilis

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