CN106334004A - Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli - Google Patents
Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli Download PDFInfo
- Publication number
- CN106334004A CN106334004A CN201610963810.6A CN201610963810A CN106334004A CN 106334004 A CN106334004 A CN 106334004A CN 201610963810 A CN201610963810 A CN 201610963810A CN 106334004 A CN106334004 A CN 106334004A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese herbal
- skin fester
- herbal medicine
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli. The Chinese herbal medicine preparation is prepared from, by weight parts, 12-22 parts of herba artemisiae scopariae, 16-20 parts of Chinese thorowax root, 12-18 parts of herba andrographitis, 8-12 parts of radix isatidis, 12-18 parts of astragalus, 12-18 parts of polygonum cuspidatum, 2-6 parts of achyranthes bidentata, 8-11 parts of honeysuckle and 2-6 parts of radix glycyrrhizae. Conventional traditional Chinese medicines are reasonably composited, effects of antibiosis and antiphlogosis and immunity enhancement are very remarkable, and the effective therapeutic medicine for treating skin fester of industrial culture sebastes schlegeli is provided for the aquaculture industry. The Chinese herbal medicine preparation has the advantages of taking effect quickly, being real in curative effect and free of medicinal residue and having no toxic or side effect. By applying the Chinese herbal medicine preparation, the skin fester of industrial culture sebastes schlegeli can be effectively controlled, and the skin fester morbidity and mortality are reduced.
Description
Technical field
The invention belongs to fishery practical technique field, specifically, it is used for preventing and treating industrial aquaculture particularly to one kind and permitted
Chinese herbal and crude drugs preparations of the flat Disease of skin fester of family name and preparation method thereof.
Background technology
The flat skin of industrial aquaculture Xu Shi includes epidermis and corium two-layer, and also contains a kind of special body of gland, energy
Secret out of substantial amounts of mucus, make skin be rich in mucosity, also can form effective physical protection barrier on fish body surface simultaneously, protect
Shield fish body is from the invasion and attack of pathogenic microorganism.Once industrial aquaculture Xu Shi puts down skin and sustains damage, easily bacterial infection and
Produce dead.Exanthemv is the skin disease that industrial aquaculture Xu Shi puts down more typically, is typically due to parasite parasitism or fish
Body is subject to the infection such as mechanical injuries secondary bacterial, fungi to cause the inflammation of skin histology, and affected area is then downright bad, tissue loss
Form defect, erosion, deep is ulcer to shallow defect.The bacterium of the flat exanthemv of industrial aquaculture Xu Shi can be caused at present
Majority belongs to Gram-negative bacteria, mainly has pseudomonad, Aeromonas, tarda, vibrios etc..Industrial aquaculture Xu Shi
After flat body surface festers, basis of microscopic observation, it is possible to find infection fish body table meat fiber necrosis, dissolving, muscle fibre interstitial
Broadening to some extent, there is oedema, simultaneously also with the infiltration of the inflammatory cells such as lymphocyte and monocyte.This disease is often
Concurrent with saprolegniasis.In low temperature rainy season, position of festering is easy to long water mold.Rotten afterbody continuation development then may result in bacillary
Septicemia, each internal organs all may occur in which different degrees of pathology.
The flat Disease of skin fester of industrial aquaculture Xu Shi, all can occur throughout the year, and it is big, for this disease to treat difficulty
Preventing and treating must adhere to the principle of " put prevention first, anti-overweight control ".If fish body table festers, treat such disease and not only will
Kill the pathogenic bacteria in water body, more important point is the bacterium killed at exanthemv, take antibacterials simultaneously orally and remove body
Interior pathogenic bacteria.
How to be treated using western medicine antibiotics at this stage, although aquatic medicine controls relatively strictly, western medicine antibiotics are indiscriminate
With situation still extremely serious so that the flat treatment difficulty of industrial aquaculture Xu Shi increases, medicament residue problem is more and more heavier, gives
Food-safety problem causes seriously to threaten.China's natural resources of Chinese medicinal materials enriches, and by rationally being screened and prescription to traditional Chinese medicine, makees
First-selected for the preventing and treating flat Disease of skin fester of industrial aquaculture Xu Shi, will have very important production practices meaning.
Chinese herbal medicine belongs to natural drug, in application and the research of China, has accumulated rich experience.Using Chinese herbal medicine
The preventing and treating flat Disease of skin fester of industrial aquaculture Xu Shi is increasingly subject to attention and the favor of people, is increasingly widely accepted, is
The mechanism of action unique with it, the mode of action and advantage are inseparable, put it briefly, and herbal control disease has adjustment and makees
With, strengthening vital QI to eliminate pathogenic factors, have no drug resistance and the incomparable feature of other medicines and the advantage such as nuisanceless, effect is good, and does not deposit
In the residue problem of antibiotic medicine, highly beneficial to the animal husbandry products export of China.In addition, Chinese herbal medicine also has price just
Preferably, wide material sources, the advantages of easy to use, are one of developing direction of fish medicine from now on.
Content of the invention
It is an object of the invention to provide a kind of Chinese herbal medicine for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi
Preparation.
The object of the present invention is achieved like this:
A kind of Chinese herbal and crude drugs preparations for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi, by following weight portion
Medicinal material is prepared from: oriental wormwood 16-22 part, radix bupleuri 16-20 part, Herba Andrographitis 12-18, Radix Isatidis 8-12 part, Radix Astragali 12-18 part, tiger
Cane 12-18 part, root of bidentate achyranthes 2-6 part, honeysuckle 8-11 part, Radix Glycyrrhizae 2-6 part.
Preferably, the described Chinese herbal and crude drugs preparations for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi, by as follows
The Chinese medicine of weight portion is prepared from: 18 parts of oriental wormwood, 18 parts of radix bupleuri, Herba Andrographitis 16,10 parts of Radix Isatidis, 16 parts of the Radix Astragali, giant knotweed 14
Part, 4 parts of the root of bidentate achyranthes, 9 parts of honeysuckle, 4 parts of Radix Glycyrrhizae.
It is further preferred that the described Chinese herbal and crude drugs preparations for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi is
Granule.
The preparation method of the Chinese herbal and crude drugs preparations that above-mentioned each Chinese medicine preparation cost is invented, comprises the steps:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh the above-mentioned Chinese medicine cleaning up by recipe quantity, pulverize, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little
When, extract filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, sediment presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder；
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear cream powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60～70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle
Agent.
The consumption of the flat Disease of skin fester Chinese herbal granules of above-mentioned preventing and treating industrial aquaculture Xu Shi is by 50-80g/100kg
The ratio of body weight mixes pharmaceutical chemistry, allows industrial aquaculture Xu Shi flat mouth to take, and being used in conjunction 5-7 days is a course for the treatment of.
The present inventor prevents and treats the flat Disease of skin fester of industrial aquaculture Xu Shi with Chinese herbal and crude drugs preparations, from our experimental result
See, application the present invention Chinese herbal and crude drugs preparations can the flat Disease of skin fester of effective control industrial aquaculture Xu Shi, reduce batch production support
Grow the M ＆ M of the flat Disease of skin fester of Xu Shi, but also do not produce drug resistance.The present invention is reasonable by traditional Chinese medicine
Prescription, anti-inflammation, strengthen immunity effect extremely notable, be culture fishery provide a kind of industrial aquaculture Xu Shi put down
The effectively treatment medicine of Disease of skin fester, has the characteristics that instant effect, curative effect really, no drug residue, without any side effects；Its
Preparation method is simple, the needs of suitable scale industrial production.
Specific embodiment
Further illustrate the present invention below by embodiment.Embodiments of the invention are only used for the present invention is described, and
It is not limitation of the present invention, under the concept thereof of the present invention, the present invention is broadly fallen into the simple modifications of preparation method of the present invention
Claimed scope.With reference to specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese herbal granules of the preventing and treating flat Disease of skin fester of industrial aquaculture Xu Shi, by oriental wormwood, radix bupleuri, Herba Andrographitis,
Radix Isatidis, the Radix Astragali, giant knotweed, the root of bidentate achyranthes, honeysuckle, Radix Glycyrrhizae composition, wherein, oriental wormwood 18kg, radix bupleuri 18kg, Herba Andrographitis 16kg, plate are blue
Root 10kg, Radix Astragali 16kg, giant knotweed 14kg, root of bidentate achyranthes 4kg, honeysuckle 9kg, Radix Glycyrrhizae 4kg.
The preparation method of the Chinese herbal granules of the flat Disease of skin fester of above-mentioned preventing and treating industrial aquaculture Xu Shi, concrete preparation step
Suddenly as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh clear oriental wormwood 18kg, radix bupleuri 18kg, Herba Andrographitis 16kg, Radix Isatidis 10kg, Radix Astragali 16kg, giant knotweed
14kg, root of bidentate achyranthes 4kg, honeysuckle 9kg, Radix Glycyrrhizae 4kg are raw material, and wash clean Chinese medicine is pulverized, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little
When, extract filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, sediment presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder；
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear cream powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60～70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle
Agent.
Embodiment 2
A kind of Chinese herbal granules of the preventing and treating flat Disease of skin fester of industrial aquaculture Xu Shi, by oriental wormwood, radix bupleuri, Herba Andrographitis,
Radix Isatidis, the Radix Astragali, giant knotweed, the root of bidentate achyranthes, honeysuckle, Radix Glycyrrhizae composition, wherein, oriental wormwood 19kg, radix bupleuri 17kg, Herba Andrographitis 15kg, plate are blue
Root 9kg, Radix Astragali 14kg, giant knotweed 13kg, root of bidentate achyranthes 3kg, honeysuckle 10kg, Radix Glycyrrhizae 5kg.
The preparation method of the Chinese herbal granules of the flat Disease of skin fester of above-mentioned preventing and treating industrial aquaculture Xu Shi, concrete preparation step
Suddenly as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh oriental wormwood 19kg, radix bupleuri 17kg, Herba Andrographitis 15kg, Radix Isatidis 9kg, Radix Astragali 14kg, giant knotweed 13kg,
Root of bidentate achyranthes 3kg, honeysuckle 10kg, Radix Glycyrrhizae 5kg are raw material, and wash clean Chinese medicine is pulverized, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little
When, extract filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, sediment presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder；
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear cream powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60～70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle
Agent.
Embodiment 3
A kind of Chinese herbal granules of the preventing and treating flat Disease of skin fester of industrial aquaculture Xu Shi, by oriental wormwood, radix bupleuri, Herba Andrographitis,
Radix Isatidis, the Radix Astragali, giant knotweed, the root of bidentate achyranthes, honeysuckle, Radix Glycyrrhizae composition, wherein, oriental wormwood 20kg, radix bupleuri 20kg, Herba Andrographitis 18kg, plate are blue
Root 12kg, Radix Astragali 18kg, giant knotweed 18kg, root of bidentate achyranthes 6kg, honeysuckle 11kg, Radix Glycyrrhizae 6kg.
The preparation method of the Chinese herbal granules of the flat Disease of skin fester of above-mentioned preventing and treating industrial aquaculture Xu Shi, concrete preparation step
Suddenly as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh oriental wormwood 19kg, radix bupleuri 17kg, Herba Andrographitis 15kg, Radix Isatidis 9kg, Radix Astragali 14kg, giant knotweed 13kg,
Root of bidentate achyranthes 3kg, honeysuckle 10kg, Radix Glycyrrhizae 5kg are raw material, and wash clean Chinese medicine is pulverized, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little
When, extract filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, sediment presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder；
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear cream powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60～70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle
Agent.
Embodiment 4 clinical testing
The consumption of the Chinese herbal granules of the flat Disease of skin fester of above-mentioned preventing and treating industrial aquaculture Xu Shi is by 60g/100kg body
The ratio of weight mixes pharmaceutical chemistry, is administered orally, and being used in conjunction 5 days is a course for the treatment of.Reach the purpose for the treatment of disease by intestinal absorption after oral.
On June 28th, 2013, the batch production that the Shandong Province Rongcheng area flat raiser of certain industrial aquaculture Xu Shi raises is supported
Grow Xu Shi and put down morbidity, clinical symptoms: the industrial aquaculture Xu Shi butterfish caudal peduncle portion of illness, trunk or skin of head are burst
Rotten, necrosis comes off, and severe patient festers and is deep into muscle layer, festers in some disease fish kiss ends.It is typical ulcer disease after diagnosing.Then use this
After Chinese herbal granules treatment, medication 2 days described in inventive embodiments 2, the state of an illness is clearly better, body color change substantially, the death rate
Reduce by sky, after 5 days, the death rate is 0, is almost recovered.
Inventor prevents and treats the flat Disease of skin fester of industrial aquaculture Xu Shi with Chinese herbal and crude drugs preparations, from our experimental result
See, no matter being prevention, or treatment, evident in efficacy, but also do not produce drug resistance, promoting through test of many times and small area should
With achieving good effect, so that fishing ground economic benefit is significantly improved.
Claims (3)
1. a kind of Chinese herbal and crude drugs preparations for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi it is characterised in that: by as follows
The Chinese medicine of weight portion is prepared from: oriental wormwood 12-22 part, radix bupleuri 16-20 part, Herba Andrographitis 12-18, Radix Isatidis 8-12 part, the Radix Astragali
12-18 part, giant knotweed 12-18 part, root of bidentate achyranthes 2-6 part, honeysuckle 8-11 part, Radix Glycyrrhizae 2-6 part.
2. the Chinese herbal and crude drugs preparations for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi according to claim 1, its
Be characterised by: be prepared from by the Chinese medicine of following weight portion: 18 parts of oriental wormwood, 18 parts of radix bupleuri, Herba Andrographitis 16,10 parts of Radix Isatidis,
16 parts of the Radix Astragali, 14 parts of giant knotweed, 4 parts of the root of bidentate achyranthes, 9 parts of honeysuckle, 4 parts of Radix Glycyrrhizae.
3. the Chinese herbal and crude drugs preparations for preventing and treating the flat Disease of skin fester of industrial aquaculture Xu Shi according to claim 1 and 2,
It is characterized in that: it is granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610963810.6A CN106334004A (en) | 2016-11-04 | 2016-11-04 | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610963810.6A CN106334004A (en) | 2016-11-04 | 2016-11-04 | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106334004A true CN106334004A (en) | 2017-01-18 |
Family
ID=57840903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610963810.6A Pending CN106334004A (en) | 2016-11-04 | 2016-11-04 | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106334004A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435292A (en) * | 2014-12-29 | 2015-03-25 | 杨成胜 | Chinese herbal medicine preparation for preventing leech ulcer disease |
-
2016
- 2016-11-04 CN CN201610963810.6A patent/CN106334004A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435292A (en) * | 2014-12-29 | 2015-03-25 | 杨成胜 | Chinese herbal medicine preparation for preventing leech ulcer disease |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104971132B (en) | It is a kind of for preventing and treating the Chinese materia medica preparation of long octopus Disease of skin fester | |
| CN106334005A (en) | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli | |
| CN106266138A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating industrialized culture left-eyed flounder Disease of skin fester | |
| CN106334004A (en) | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli | |
| CN102805836A (en) | Chinese traditional medical composition for treating primary hepatic carcinoma and preparation method thereof | |
| CN106420966A (en) | Chinese herbal medicine preparation for preventing common diseases of pond-cultured Fenneropenaeus chinensiss | |
| CN106266146A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Concha Tridacna squamosa Common Diseases | |
| CN106334017A (en) | Chinese herbal medicine preparation for preventing skin fester of offshore cage culture fugu rubripes | |
| CN106265984A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating pond culture Penaeus vannamei Common Diseases | |
| WO2021012460A1 (en) | Medicine for preventing and treating bacterial enteritis of eels, and preparation method therefor | |
| CN106266083A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating pond culture red fin east Disease of skin fester | |
| CN106334013A (en) | Chinese herbal medicine preparation for preventing skin fester of pond culture Takifugu flavidus | |
| CN106334014A (en) | Chinese herbal medicine preparation for preventing skin fester of industrial cultureTakifugu flavidus | |
| CN106265965A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating industrialized culture black porgy Disease of skin fester | |
| CN106361810A (en) | Chinese herbal medicine preparation for preventing and treating skin fester diseases of pseudosciaena crocea in industrial aquaculture | |
| CN106344669A (en) | Chinese herbal medicine preparation for preventing and treating skin ulcer of offshore net cage cultured sebastes schlegeli | |
| CN106377601A (en) | Traditional Chinese herbal medicine preparation for preventing and treating skin ulceration of flatfish cultured in offshore cages | |
| CN106266139A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating industrialized culture red fin east Disease of skin fester | |
| CN106361873A (en) | Chinese herbal medicine preparation for preventing and controlling skin fester disease of black sea bream cultured in inshore net cage | |
| CN106266005A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating coastal waters cage culture Paralichthys olivaceus Disease of skin fester | |
| CN106309641A (en) | Chinese herbal medicine preparation for preventing and treating skin fester disease of offshore cage-cultured takifugu flavidus | |
| CN106389553A (en) | Chinese herbal medicine preparation for controlling common diseases of industrialized bred conches | |
| CN106361834A (en) | Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei | |
| CN106309580A (en) | Chinese herbal medicine preparation for preventing and treating common diseases of pond-cultured portunus trituberculatus | |
| CN106266145A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification green grass or young crops willow clam Common Diseases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170118 |
|
| WD01 | Invention patent application deemed withdrawn after publication |