CN106361834A - Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei - Google Patents
Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention discloses a Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei. The Chinese herbal preparation is prepared from, by weight, 12-22 parts of capillary wormwood herb, 16-20 parts of radix bupleuri, 12-18 parts of radix sophorae flavescentis, 8-12 parts of fructus forsythiae, 12-18 parts of moutan bark, 12-18 parts of folium perillae, 2-6 parts of radix achyranthis bidentatae, 8-11 parts of honeysuckle flowers and 2-6 parts of gallnut. Traditional Chinese herbs are reasonably composited, the effects of resisting bacteria, diminishing inflammations and enhancing the immunity are extremely significant, an effective treatment drug for the common diseases generated in industrialized aquaculture of the penaeus vannamei is provided for the aquaculture industry, and the advantages that the effects are rapidly achieved, the treatment effect is exact, no medicine residue exists, and no toxic or side effect is generated are achieved. By applying the Chinese herbal preparation, the common diseases generated in industrialized aquaculture of the penaeus vannamei can be effectively controlled, and the morbidity rate and the mortality rate which are caused by the common diseases are decreased.
Description
Technical field
The invention belongs to fishery practical technique field, specifically, it is used for preventing and treating industrialized culture south particularly to one kind
Chinese herbal and crude drugs preparationses of Penaeus vannamei Boone Common Diseases and preparation method thereof.
Background technology
Penaeus vannamei (penaeus vannamei, boone, 1931): scientific name Litoenaeus vannamei, belong to Arthropoda, be
Extensively warm eurysalinity torrid zone shrimps.Penaeus vannamei is commonly called as white limb shrimp (white-leg shrimp), white shrimp (white again
Shrimp), once it is translated as Penaeus vannamei, exactly likes Chinese prawn, Penaeus merguiensis de man., average life at least can exceed 32
Month.Adult is the longest, and up to 24cm, carapace is relatively thin, and normal body colour is shallow cinerouss, and whole body does not have speckle.Step is in often Chalk shape,
Therefore have the title of white limb shrimp.
The Common Diseases of industrialized culture Penaeus vannamei, all can occur throughout the year, and it is big, for this disease to treat difficulty
Preventing and treating must adhere to the principle of " put prevention first, anti-overweight control ".If shrimp body surface festers, treat such disease and not only will
Kill the pathogenic bacterium in water body, more important point is the antibacterial killed at skin ulceration, take antibacterials simultaneously orally and remove body
Interior pathogenic bacterium.
How to be treated using western medicine antibiotics at this stage, although aquatic medicine controls relatively strictly, western medicine antibiotics are indiscriminate
With situation still extremely serious so that the treatment difficulty of industrialized culture Penaeus vannamei increases, medicament residue problem is more and more heavier,
Cause seriously to threaten to food-safety problem.China's natural resources of Chinese medicinal materials enriches, by rationally being screened and prescription to Chinese medicine,
First-selected as preventing and treating industrialized culture Penaeus vannamei Common Diseases, will have very important production practices meaning.
Chinese herbal medicine belongs to natural drug, in application and the research of China, has accumulated rich experience.Using Chinese herbal medicine
Preventing and treating industrialized culture Penaeus vannamei Common Diseases are increasingly subject to attention and the favor of people, are increasingly widely accepted, are
The mechanism of action unique with it, model of action and advantage are inseparable, put it briefly, and herbal control disease has adjustment and makees
With, strengthening vital QI to eliminate pathogenic factors, have no drug resistance and the incomparable feature of other medicines and the advantage such as nuisanceless, effect is good, and does not deposit
In the residue problem of antibiotic medicine, highly beneficial to the animal husbandry products export of China.In addition, Chinese herbal medicine also has price just
Preferably, wide material sources, the advantages of easy to use, are one of developing direction of fish medicine from now on.
Content of the invention
It is an object of the invention to provide a kind of Chinese herbal medicine for preventing and treating industrialized culture Penaeus vannamei Common Diseases
Preparation.
The object of the present invention is achieved like this:
A kind of Chinese herbal and crude drugs preparationses for preventing and treating industrialized culture Penaeus vannamei Common Diseases, by following weight portion
Medical material is prepared from: Herba Artemisiae Scopariae 16-22 part, Radix Bupleuri 16-20 part, Radix Sophorae Flavescentiss 12-18, Fructus Forsythiae 8-12 part, Cortex Moutan 12-18 part, Folium Perillae
12-18 part, Radix Achyranthis Bidentatae 2-6 part, Flos Lonicerae 8-11 part, Galla Chinensiss 2-6 part.
Preferably, the described Chinese herbal and crude drugs preparationses for preventing and treating industrialized culture Penaeus vannamei Common Diseases, by as follows
The Chinese crude drug of weight portion is prepared from: 18 parts of Herba Artemisiae Scopariae, 18 parts of Radix Bupleuri, Radix Sophorae Flavescentiss 16,10 parts of Fructus Forsythiae, 16 parts of Cortex Moutan, 14 parts of Folium Perillae,
4 parts of Radix Achyranthis Bidentatae, 9 parts of Flos Lonicerae, 4 parts of Galla Chinensiss.
It is further preferred that the described Chinese herbal and crude drugs preparationses for preventing and treating industrialized culture Penaeus vannamei Common Diseases are
Granule.
The preparation method of the Chinese herbal and crude drugs preparationses that above-mentioned each Chinese crude drug preparation cost is invented, comprises the steps:
The first step, prepares clear paste powder:
1) get the raw materials ready: weigh the above-mentioned Chinese crude drug cleaning up by recipe quantity, pulverize, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medical material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second decocts the water heating extraction adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear paste powder；
Second step, according to clear paste powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, takes out, cools and obtain final product described granule
Agent.
The consumption of above-mentioned preventing and treating industrialized culture Penaeus vannamei Common Diseases Chinese medicine granules is by 50-80g/100kg
The ratio of body weight mixes pharmaceutical chemistry, allows industrialized culture Penaeus vannamei to be administered orally, and being used in conjunction 5-7 days is a course for the treatment of.
The present inventor prevents and treats industrialized culture Penaeus vannamei Common Diseases with Chinese herbal and crude drugs preparationses, from our experimental result
See, application the present invention Chinese herbal and crude drugs preparationses can effective control industrialized culture Penaeus vannamei Common Diseases, reduce batch production support
Grow the M ＆ M of Penaeus vannamei Common Diseases, but also do not produce drug resistance.The present invention is reasonable by Chinese medicine
Prescription, anti-inflammation, enhancing immunity effect extremely notable, it is white to be that culture fishery provides a kind of industrialized culture South America
The effectively treatment medicine of prawn Common Diseases, has the characteristics that instant effect, curative effect really, no drug residue, without any side effects；Its
Preparation method is simple, the needs of suitable scale industrial production.
Specific embodiment
Further illustrate the present invention below by embodiment.Embodiments of the invention are only used for the present invention is described, and
It is not limitation of the present invention, under the concept thereof of the present invention, the present invention is broadly fallen into the simple modifications of preparation method of the present invention
Claimed scope.With reference to specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine granules of preventing and treating industrialized culture Penaeus vannamei Common Diseases, by Herba Artemisiae Scopariae, Radix Bupleuri, Radix Sophorae Flavescentiss, company
Stick up, Cortex Moutan, Folium Perillae, Radix Achyranthis Bidentatae, Flos Lonicerae, Galla Chinensiss composition, wherein, Herba Artemisiae Scopariae 18kg, Radix Bupleuri 18kg, Radix Sophorae Flavescentiss 16kg, Fructus Forsythiae
10kg, Cortex Moutan 16kg, Folium Perillae 14kg, Radix Achyranthis Bidentatae 4kg, Flos Lonicerae 9kg, Galla Chinensiss 4kg.
The preparation method of the Chinese medicine granules of above-mentioned preventing and treating industrialized culture Penaeus vannamei Common Diseases, concrete preparation step
Suddenly as follows:
The first step, prepares clear paste powder:
1) get the raw materials ready: weigh clear Herba Artemisiae Scopariae 18kg, Radix Bupleuri 18kg, Radix Sophorae Flavescentiss 16kg, Fructus Forsythiae 10kg, Cortex Moutan 16kg, Folium Perillae 14kg,
Radix Achyranthis Bidentatae 4kg, Flos Lonicerae 9kg, Galla Chinensiss 4kg are raw material, and wash clean Chinese crude drug is pulverized, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medical material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second decocts the water heating extraction adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear paste powder；
Second step, according to clear paste powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, takes out, cools and obtain final product described granule
Agent.
Embodiment 2
A kind of Chinese medicine granules of preventing and treating industrialized culture Penaeus vannamei Common Diseases, by Herba Artemisiae Scopariae, Radix Bupleuri, Radix Sophorae Flavescentiss, company
Stick up, Cortex Moutan, Folium Perillae, Radix Achyranthis Bidentatae, Flos Lonicerae, Galla Chinensiss composition, wherein, Herba Artemisiae Scopariae 19kg, Radix Bupleuri 17kg, Radix Sophorae Flavescentiss 15kg, Fructus Forsythiae
9kg, Cortex Moutan 14kg, Folium Perillae 13kg, Radix Achyranthis Bidentatae 3kg, Flos Lonicerae 10kg, Galla Chinensiss 5kg.
The preparation method of the Chinese medicine granules of above-mentioned preventing and treating industrialized culture Penaeus vannamei Common Diseases, concrete preparation step
Suddenly as follows:
The first step, prepares clear paste powder:
1) get the raw materials ready: weigh Herba Artemisiae Scopariae 19kg, Radix Bupleuri 17kg, Radix Sophorae Flavescentiss 15kg, Fructus Forsythiae 9kg, Cortex Moutan 14kg, Folium Perillae 13kg, cattle
Knee joint 3kg, Flos Lonicerae 10kg, Galla Chinensiss 5kg are raw material, and wash clean Chinese crude drug is pulverized, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medical material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second decocts the water heating extraction adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear paste powder；
Second step, according to clear paste powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, takes out, cools and obtain final product described granule
Agent.
Embodiment 3
A kind of Chinese medicine granules of preventing and treating industrialized culture Penaeus vannamei Common Diseases, by Herba Artemisiae Scopariae, Radix Bupleuri, Radix Sophorae Flavescentiss, company
Stick up, Cortex Moutan, Folium Perillae, Radix Achyranthis Bidentatae, Flos Lonicerae, Galla Chinensiss composition, wherein, Herba Artemisiae Scopariae 20kg, Radix Bupleuri 20kg, Radix Sophorae Flavescentiss 18kg, Fructus Forsythiae
12kg, Cortex Moutan 18kg, Folium Perillae 18kg, Radix Achyranthis Bidentatae 6kg, Flos Lonicerae 11kg, Galla Chinensiss 6kg.
The preparation method of the Chinese medicine granules of above-mentioned preventing and treating industrialized culture Penaeus vannamei Common Diseases, concrete preparation step
Suddenly as follows:
The first step, prepares clear paste powder:
1) get the raw materials ready: weigh Herba Artemisiae Scopariae 19kg, Radix Bupleuri 17kg, Radix Sophorae Flavescentiss 15kg, Fructus Forsythiae 9kg, Cortex Moutan 14kg, Folium Perillae 13kg, cattle
Knee joint 3kg, Flos Lonicerae 10kg, Galla Chinensiss 5kg are raw material, and wash clean Chinese crude drug is pulverized, standby；
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medical material total amount, keeps 2 hours, carry after ebuillition of heated
Take liquid to filter through 200 mesh filters and enter settling tank；Second decocts the water heating extraction adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution filters through 200 mesh filters and enters settling tank；
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate: when supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of mensure) in triple effect evaporator,
Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place,
Filtration；Concentrating and mix to relative density is to go out cream when 1.10～1.22 (90 DEG C of mensure), to storage cream bucket, standby；
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78～82 DEG C, 12～18 hours drying times；
6) beat powder: smashing fineness 80 mesh sieve, obtain clear paste powder；
Second step, according to clear paste powder: starch: 55% ethanol is that the weight ratio of 1:1～3:0.1～0.3 weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, takes out, cools and obtain final product described granule
Agent.
Embodiment 4 clinical trial
The consumption of the Chinese medicine granules of above-mentioned preventing and treating industrialized culture Penaeus vannamei Common Diseases is by 60g/100kg body
The ratio of weight mixes pharmaceutical chemistry, is administered orally, and being used in conjunction 5 days is a course for the treatment of.Reach the purpose for the treatment of disease by intestinal absorption after oral.
On June 28th, 2013, the batch production that certain industrialized culture culture of Penaeus vannamei family of Shandong Province Rongcheng area is raised
Cultivation Penaeus vannamei morbidity, clinical symptoms: the industrialized culture Penaeus vannamei fish tail shank of illness, trunk or head skin
Skin festers, and necrosis comes off, and severe patient festers and is deep into Musclar layer, festers in some disease fish kiss ends.It is typical ulcer disease after diagnosing.Then
Treated with Chinese medicine granules described in the embodiment of the present invention 2, after medication 2 days, the state of an illness is clearly better, body color change substantially, extremely
Rate of dying reduces by sky, and after 5 days, mortality rate is 0, is almost recovered.
Inventor prevents and treats industrialized culture Penaeus vannamei Common Diseases with Chinese herbal and crude drugs preparationses, from our experimental result
See, no matter being prevention, or treatment, evident in efficacy, but also do not produce drug resistance, promoting through test of many times and small area should
With achieving good effect, so that fishing ground economic benefit is significantly improved.
Claims (3)
1. a kind of Chinese herbal and crude drugs preparationses for preventing and treating industrialized culture Penaeus vannamei Common Diseases it is characterised in that: by as follows
The Chinese crude drug of weight portion is prepared from: Herba Artemisiae Scopariae 12-22 part, Radix Bupleuri 16-20 part, Radix Sophorae Flavescentiss 12-18, Fructus Forsythiae 8-12 part, Cortex Moutan 12-
18 parts, Folium Perillae 12-18 part, Radix Achyranthis Bidentatae 2-6 part, Flos Lonicerae 8-11 part, Galla Chinensiss 2-6 part.
2. the Chinese herbal and crude drugs preparationses for preventing and treating industrialized culture Penaeus vannamei Common Diseases according to claim 1, its
It is characterised by: be prepared from by the Chinese crude drug of following weight portion: 18 parts of Herba Artemisiae Scopariae, 18 parts of Radix Bupleuri, Radix Sophorae Flavescentiss 16,10 parts of Fructus Forsythiae, Paeonia suffruticosa
16 parts of skin, 14 parts of Folium Perillae, 4 parts of Radix Achyranthis Bidentatae, 9 parts of Flos Lonicerae, 4 parts of Galla Chinensiss.
3. the Chinese herbal and crude drugs preparationses for preventing and treating industrialized culture Penaeus vannamei Common Diseases according to claim 1 and 2,
It is characterized in that: it is granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610875230.1A CN106361834A (en) | 2016-09-30 | 2016-09-30 | Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610875230.1A CN106361834A (en) | 2016-09-30 | 2016-09-30 | Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106361834A true CN106361834A (en) | 2017-02-01 |
Family
ID=57894753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610875230.1A Withdrawn CN106361834A (en) | 2016-09-30 | 2016-09-30 | Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106361834A (en) |
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2016
- 2016-09-30 CN CN201610875230.1A patent/CN106361834A/en not_active Withdrawn
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| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170201 |
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| WW01 | Invention patent application withdrawn after publication |