CN106421067A - Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria - Google Patents
Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria Download PDFInfo
- Publication number
- CN106421067A CN106421067A CN201610986660.0A CN201610986660A CN106421067A CN 106421067 A CN106421067 A CN 106421067A CN 201610986660 A CN201610986660 A CN 201610986660A CN 106421067 A CN106421067 A CN 106421067A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese herbal
- mercenaria
- common diseases
- bred
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria. The Chinese herbal medicine is prepared from the traditional Chinese medicinal materials in parts by weight as follows: 16-20 parts of rhizoma coptidis, 16-20 parts of fructus gardeniae, 12-18 parts of radix sophorae flavescentis, 8-12 parts of herba andrographitis, 12-18 parts of radix scutellariae, 12-18 parts of purple perilla, 2-6 parts of lonicera japonica, 8-11 parts of dandelions, 2-6 parts of cortex phellodendri and 8-20 parts of licorice roots. By the rational coordination of the traditional Chinese herbal medicines, the common diseases of the factory bred mercenaria can be prevented through disinfection and sterilization; meanwhile, toxic and harmful chemicals cannot be left in pond water and the mercenaria by the use of a Chinese herbal medicine preparation. By the adoption of the Chinese herbal medicine preparation, the common diseases of the factory bred mercenaria can be effectively controlled, the survival rate and the egg production rate of the factory bred mercenaria are increased, and great significance in breeding of the factory bred mercenaria is realized.
Description
Technical field
The invention belongs to fishery practical technique field, specifically, more particularly to a kind of for preventing and treating plant modification U.S.
Chinese herbal and crude drugs preparationses of state's quahog Common Diseases and preparation method thereof.
Background technology
U.S. quahog (Mercenaria) original is distributed in east coast of the United States, is the main of the littoral and beach of U.S., Atlantic
Cultivated shellfish, nutrition and economic worth are higher, and shell is extracted by quahog but also as advanced processes product, the raw material of ornament
Mercenene can suppress the growth of tumor.U.S. quahog is extensively warm, wide salt shellfish, to the tolerance of less salt and high temperature all relatively
By force, with the speed of growth faster, sexual maturity can reach in 1 year.Its to substrate no particular/special requirement, in husky bottom, husky mud bottom, mud
The beach of multiple substrates such as bottom and coastal bed and shallow sea, can normal growth, development.Domestic examination in 2004 is supported and is succeeded.
In recent years, China's Coastal Areas cultivated shellfish massive mortality event frequently occurs, the shellfish kind being related to and support
Grow area and scope is continuously increased, make shellfishery suffer great economic loss.Cultivated shellfish massive mortality problem is
Cause the extensive attention at aquaculture family.The cultivated shellfish bionosis cause of death, mainly has：Virus, antibacterial, parasitic original
Worm, rickettsia-like organism, class chlamydia, mycoplasma-like organism(MLO) etc..
Chinese herbal medicine belongs to natural drug, in application and the research of China, has accumulated rich experience.Using Chinese herbal medicine come
Preventing and treating plant modification U.S. quahog Common Diseases are increasingly widely accepted, are increasingly by attention and the favor of people
The mechanism of action unique with which, model of action and advantage are inseparable, put it briefly, and herbal control disease has adjustment and makees
With, strengthening vital QI to eliminate pathogenic factors, have no drug resistance and the incomparable feature of other medicines and the advantage such as nuisanceless, effect is good, and does not deposit
In the residue problem of antibiotic medicine, products export is bred to the Aquatic product of China highly beneficial.In addition, Chinese herbal medicine also has price just
Preferably, wide material sources, the advantages of easy to use, are one of developing direction of fish medicine from now on.
Content of the invention
It is an object of the invention to provide a kind of Chinese herbal medicine for preventing and treating plant modification U.S. quahog Common Diseases
Preparation.
The object of the present invention is achieved like this：
A kind of Chinese herbal and crude drugs preparationses for preventing and treating plant modification U.S. quahog Common Diseases, by following weight portion
Medical material is prepared from：Rhizoma Coptidis 16-20 part, Fructus Gardeniae 16-20 part, Radix Sophorae Flavescentiss 12-18, Herba Andrographis 8-12 part, Radix Scutellariae 12-18 part, Folium Perillae
12-18 part, Flos Lonicerae 2-6 part, Herba crotalariae albidae 8-11 part, Cortex Phellodendri 2-6 part, Radix Glycyrrhizae 8-20 part.
Preferably, the described Chinese herbal and crude drugs preparationses for preventing and treating plant modification U.S. quahog Common Diseases, by as follows
The Chinese crude drug of weight portion is prepared from：18 parts of Rhizoma Coptidis, 18 parts of Fructus Gardeniae, Radix Sophorae Flavescentiss 16,10 parts of Herba Andrographis, 16 parts of Radix Scutellariae, 14 parts of Folium Perillae,
4 parts of Flos Lonicerae, 9 parts of Herba crotalariae albidae, 4 parts of Cortex Phellodendri, 11 parts of Radix Glycyrrhizae.
It is further preferred that the described Chinese herbal and crude drugs preparationses for preventing and treating plant modification U.S. quahog Common Diseases are
Granule.
By the preparation method of the Chinese herbal and crude drugs preparationses of above-mentioned each Chinese crude drug preparation cost invention, comprise the steps：
The first step, prepares clear paste powder：
1) get the raw materials ready：The above-mentioned Chinese crude drug for cleaning up is weighed by recipe quantity, is crushed, standby；
2) decoct：Add water to cook, first decocts 8 times for adding water as medical material total amount per tank, is kept for 2 hours, carry after ebuillition of heated
Taking liquid entrance settling tank is filtered through 200 mesh filters；Second decocts the water heating extraction for adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution is filtered through 200 mesh filters and enters settling tank；
3) precipitate：Liquid precipitate being extracted 12 hours in settling tank, extracts supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate：When supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of measure) in triple effect evaporator,
200 mesh filter of dilute clear cream is filtered in suction vacuum decompressioning and concentrating tank, is added ethanol to alcohol content 60% (v/v), place,
Filtration；It is to go out cream when 1.10～1.22 (90 DEG C of measure) to concentrate and mix to relative density, to storage cream bucket, standby；
5) dry：Wherein vacuum：0.01MPa, temperature：78～82 DEG C, 12～18 hours drying times；
6) powder is beaten：80 mesh sieve of smashing fineness, obtains clear paste powder；
Second step, according to clear paste powder：Starch：55% ethanol is 1：1～3：0.1～0.3 weight ratio weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, is stirred 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, is taken out, is cooled and obtain final product described granule
Agent.
The consumption of above-mentioned preventing and treating plant modification U.S. quahog Common Diseases Chinese medicine granules be by 60-80g/100kg
The ratio of body weight mixes pharmaceutical chemistry, allows plant modification U.S. quahog to be administered orally, and is used in conjunction 5-7 days for a course for the treatment of.
The present inventor prevents and treats plant modification U.S. quahog Common Diseases with Chinese herbal and crude drugs preparationses, from our experimental result
See, apply the present invention Chinese herbal and crude drugs preparationses can effective control plant modification U.S. quahog Common Diseases, reduce batch production numerous
The M ＆ M of U.S.'s quahog Common Diseases is educated, but also does not produce drug resistance.The present invention is reasonable by Chinese medicine
Prescription, anti-inflammation, enhancing immunity effect extremely notable, be Aquatic product breed industry provide a kind of plant modification U.S. hard
The effectively treatment medicine of shell clam Common Diseases, have the characteristics that instant effect, curative effect really, no drug residue, without any side effects；Its
Preparation method is simple, the needs of suitable large-scale production.
Specific embodiment
The present invention is further illustrated below by embodiment.Embodiments of the invention are only used for the present invention is described, and
It is not limitation of the present invention, under the concept thereof of the present invention, the present invention is belonged to the simple modifications of preparation method of the present invention
Claimed scope.With reference to specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine granules of preventing and treating plant modification U.S. quahog Common Diseases, by Rhizoma Coptidis, Fructus Gardeniae, Radix Sophorae Flavescentiss, wear
Heart lotus, Radix Scutellariae, Folium Perillae, Flos Lonicerae, Herba crotalariae albidae, Cortex Phellodendri, Radix Glycyrrhizae composition, wherein, Rhizoma Coptidis 18kg, Fructus Gardeniae 18kg, Radix Sophorae Flavescentiss 16kg,
Herba Andrographis 10kg, Radix Scutellariae 16kg, Folium Perillae 14kg, Flos Lonicerae 4kg, Herba crotalariae albidae 9kg, Cortex Phellodendri 4kg, Radix Glycyrrhizae 11kg.
The preparation method of the Chinese medicine granules of above-mentioned preventing and treating plant modification U.S. quahog Common Diseases, concrete preparation walks
Rapid as follows：
The first step, prepares clear paste powder：
1) get the raw materials ready：Weigh clear Rhizoma Coptidis 18kg, Fructus Gardeniae 18kg, Radix Sophorae Flavescentiss 16kg, Herba Andrographis 10kg, Radix Scutellariae 16kg, Folium Perillae 14kg,
Flos Lonicerae 4kg, Herba crotalariae albidae 9kg, Cortex Phellodendri 4kg, Radix Glycyrrhizae 11kg are raw material, and wash clean Chinese crude drug is crushed, standby；
2) decoct：Add water to cook, first decocts 8 times for adding water as medical material total amount per tank, is kept for 2 hours, carry after ebuillition of heated
Taking liquid entrance settling tank is filtered through 200 mesh filters；Second decocts the water heating extraction for adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution is filtered through 200 mesh filters and enters settling tank；
3) precipitate：Liquid precipitate being extracted 12 hours in settling tank, extracts supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate：When supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of measure) in triple effect evaporator,
200 mesh filter of dilute clear cream is filtered in suction vacuum decompressioning and concentrating tank, is added ethanol to alcohol content 60% (v/v), place,
Filtration；It is to go out cream when 1.10～1.22 (90 DEG C of measure) to concentrate and mix to relative density, to storage cream bucket, standby；
5) dry：Wherein vacuum：0.01MPa, temperature：78～82 DEG C, 12～18 hours drying times；
6) powder is beaten：80 mesh sieve of smashing fineness, obtains clear paste powder；
Second step, according to clear paste powder：Starch：55% ethanol is 1：1～3：0.1～0.3 weight ratio weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, is stirred 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, is taken out, is cooled and obtain final product described granule
Agent.
Embodiment 2
A kind of Chinese medicine granules of preventing and treating plant modification U.S. quahog Common Diseases, by Rhizoma Coptidis, Fructus Gardeniae, Radix Sophorae Flavescentiss, wear
Heart lotus, Radix Scutellariae, Folium Perillae, Flos Lonicerae, Herba crotalariae albidae, Cortex Phellodendri, Radix Glycyrrhizae composition, wherein, Rhizoma Coptidis 19kg, Fructus Gardeniae 17kg, Radix Sophorae Flavescentiss 15kg,
Herba Andrographis 9kg, Radix Scutellariae 14kg, Folium Perillae 13kg, Flos Lonicerae 3kg, Herba crotalariae albidae 10kg, Cortex Phellodendri 5kg, Radix Glycyrrhizae 13kg.
The preparation method of the Chinese medicine granules of above-mentioned preventing and treating plant modification U.S. quahog Common Diseases, concrete preparation walks
Rapid as follows：
The first step, prepares clear paste powder：
1) get the raw materials ready：Weigh Rhizoma Coptidis 19kg, Fructus Gardeniae 17kg, Radix Sophorae Flavescentiss 15kg, Herba Andrographis 9kg, Radix Scutellariae 14kg, Folium Perillae 13kg, gold
Flos Lonicerae 3kg, Herba crotalariae albidae 10kg, Cortex Phellodendri 5kg, Radix Glycyrrhizae 13kg are raw material, and wash clean Chinese crude drug is crushed, standby；
2) decoct：Add water to cook, first decocts 8 times for adding water as medical material total amount per tank, is kept for 2 hours, carry after ebuillition of heated
Taking liquid entrance settling tank is filtered through 200 mesh filters；Second decocts the water heating extraction for adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution is filtered through 200 mesh filters and enters settling tank；
3) precipitate：Liquid precipitate being extracted 12 hours in settling tank, extracts supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate：When supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of measure) in triple effect evaporator,
200 mesh filter of dilute clear cream is filtered in suction vacuum decompressioning and concentrating tank, is added ethanol to alcohol content 60% (v/v), place,
Filtration；It is to go out cream when 1.10～1.22 (90 DEG C of measure) to concentrate and mix to relative density, to storage cream bucket, standby；
5) dry：Wherein vacuum：0.01MPa, temperature：78～82 DEG C, 12～18 hours drying times；
6) powder is beaten：80 mesh sieve of smashing fineness, obtains clear paste powder；
Second step, according to clear paste powder：Starch：55% ethanol is 1：1～3：0.1～0.3 weight ratio weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, is stirred 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, is taken out, is cooled and obtain final product described granule
Agent.
Embodiment 3
A kind of Chinese medicine granules of preventing and treating plant modification U.S. quahog Common Diseases, by Rhizoma Coptidis, Fructus Gardeniae, Radix Sophorae Flavescentiss, wear
Heart lotus, Radix Scutellariae, Folium Perillae, Flos Lonicerae, Herba crotalariae albidae, Cortex Phellodendri, Radix Glycyrrhizae composition, wherein, Rhizoma Coptidis 20kg, Fructus Gardeniae 20kg, Radix Sophorae Flavescentiss 18kg,
Herba Andrographis 12kg, Radix Scutellariae 18kg, Folium Perillae 18kg, Flos Lonicerae 6kg, Herba crotalariae albidae 11kg, Cortex Phellodendri 6kg, Radix Glycyrrhizae 15kg.
The preparation method of the Chinese medicine granules of above-mentioned preventing and treating plant modification U.S. quahog Common Diseases, concrete preparation walks
Rapid as follows：
The first step, prepares clear paste powder：
1) get the raw materials ready：Weigh Rhizoma Coptidis 19kg, Fructus Gardeniae 17kg, Radix Sophorae Flavescentiss 15kg, Herba Andrographis 9kg, Radix Scutellariae 14kg, Folium Perillae 13kg, gold
Flos Lonicerae 3kg, Herba crotalariae albidae 10kg, Cortex Phellodendri 5kg, Radix Glycyrrhizae 15kg are raw material, and wash clean Chinese crude drug is crushed, standby；
2) decoct：Add water to cook, first decocts 8 times for adding water as medical material total amount per tank, is kept for 2 hours, carry after ebuillition of heated
Taking liquid entrance settling tank is filtered through 200 mesh filters；Second decocts the water heating extraction for adding 6 times of medical material amount, protects boiling 1.5 little
When, extracting solution is filtered through 200 mesh filters and enters settling tank；
3) precipitate：Liquid precipitate being extracted 12 hours in settling tank, extracts supernatant and filter through 200 mesh filters and steam to triple effect
Send out in device, precipitate presses offal treatment；
4) concentrate：When supernatant is concentrated into relative density for 1.05～1.10 (40 DEG C of measure) in triple effect evaporator,
200 mesh filter of dilute clear cream is filtered in suction vacuum decompressioning and concentrating tank, is added ethanol to alcohol content 60% (v/v), place,
Filtration；It is to go out cream when 1.10～1.22 (90 DEG C of measure) to concentrate and mix to relative density, to storage cream bucket, standby；
5) dry：Wherein vacuum：0.01MPa, temperature：78～82 DEG C, 12～18 hours drying times；
6) powder is beaten：80 mesh sieve of smashing fineness, obtains clear paste powder；
Second step, according to clear paste powder：Starch：55% ethanol is 1：1～3：0.1～0.3 weight ratio weighs clear paste powder, paste
Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%；
3rd step, clear paste powder and starch is put in trough type mixing machine, is stirred 20 minutes, be slowly added into 55% while stirring
Ethanol, to making soft material, is pelletized with 12 mesh stainless steel sifts, 60～70 DEG C of dryings 2 hours, is taken out, is cooled and obtain final product described granule
Agent.
4 clinical trial of embodiment
The consumption of the Chinese medicine granules of above-mentioned preventing and treating plant modification U.S. quahog Common Diseases be by 60g/100kg body
The ratio of weight mixes pharmaceutical chemistry, is administered orally, and is used in conjunction 5 days for a course for the treatment of.The purpose for the treatment of disease is reached after oral by intestinal absorption.
On July 20th, 2016, the plant modification U.S. quahog morbidity that Shandong Province Weihai City nursery is bred, face
Bed symptom：The plant modification U.S. quahog tentacle of illness, trunk or skin of head fester, and necrosis comes off, and severe patient is burst
Rotten it is deep into Musclar layer.It is typical ulcer disease after diagnosing.Chinese medicine granules treatment, medication 2 days described in the embodiment of the present invention 2 are used then
Afterwards, the state of an illness is clearly better, and body color change is obvious, and mortality rate reduces by day, and after 7 days, mortality rate is 0, to be almost recovered.
Inventor prevents and treats plant modification U.S. quahog Common Diseases with Chinese herbal and crude drugs preparationses, from our experimental result
See, no matter it is prevention, or treatment, evident in efficacy, but also drug resistance is not produced, promoting through test of many times and small area should
With achieving good effect, significantly improve breeding field economic benefit.
Claims (3)
1. a kind of Chinese herbal and crude drugs preparationses for preventing and treating plant modification U.S. quahog Common Diseases, it is characterised in that：By as follows
The Chinese crude drug of weight portion is prepared from：Rhizoma Coptidis 16-20 part, Fructus Gardeniae 16-20 part, Radix Sophorae Flavescentiss 12-18, Herba Andrographis 8-12 part, Radix Scutellariae 12-
18 parts, Folium Perillae 12-18 part, Flos Lonicerae 2-6 part, Herba crotalariae albidae 8-11 part, Cortex Phellodendri 2-6 part, Radix Glycyrrhizae 8-20 part.
2. Chinese herbal and crude drugs preparationses for preventing and treating plant modification U.S. quahog Common Diseases according to claim 1, its
It is characterised by：It is prepared from by the Chinese crude drug of following weight portion：18 parts of Rhizoma Coptidis, 18 parts of Fructus Gardeniae, Radix Sophorae Flavescentiss 16,10 parts of Herba Andrographis, Huang
16 parts of a kind of reed mentioned in ancient books, 14 parts of Folium Perillae, 4 parts of Flos Lonicerae, 9 parts of Herba crotalariae albidae, 4 parts of Cortex Phellodendri, 11 parts of Radix Glycyrrhizae.
3. Chinese herbal and crude drugs preparationses for preventing and treating plant modification U.S. quahog Common Diseases according to claim 1 and 2,
It is characterized in that：It is granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610986660.0A CN106421067A (en) | 2016-11-10 | 2016-11-10 | Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610986660.0A CN106421067A (en) | 2016-11-10 | 2016-11-10 | Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106421067A true CN106421067A (en) | 2017-02-22 |
Family
ID=58208755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610986660.0A Withdrawn CN106421067A (en) | 2016-11-10 | 2016-11-10 | Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106421067A (en) |
-
2016
- 2016-11-10 CN CN201610986660.0A patent/CN106421067A/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104971132B (en) | It is a kind of for preventing and treating the Chinese materia medica preparation of long octopus Disease of skin fester | |
| CN106421067A (en) | Chinese herbal medicine preparation for controlling common diseases of factory bred mercenaria | |
| CN106420966A (en) | Chinese herbal medicine preparation for preventing common diseases of pond-cultured Fenneropenaeus chinensiss | |
| CN106266145A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification green grass or young crops willow clam Common Diseases | |
| CN106266146A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Concha Tridacna squamosa Common Diseases | |
| CN106265984A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating pond culture Penaeus vannamei Common Diseases | |
| CN106334005A (en) | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli | |
| CN106334021A (en) | Chinese herbal medicine preparation for preventing skin fester of industrial culture ruditapes philippinarum | |
| CN106266138A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating industrialized culture left-eyed flounder Disease of skin fester | |
| CN106361834A (en) | Chinese herbal preparation for preventing and treating common diseases generated in industrialized aquaculture of penaeus vannamei | |
| CN106491764A (en) | A kind of Chinese herbal and crude drugs preparationses for preventing and treating plant modification Pinna pectinata Common Diseases | |
| CN106266166A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Russia Stichopus japonicus Common Diseases | |
| CN106309580A (en) | Chinese herbal medicine preparation for preventing and treating common diseases of pond-cultured portunus trituberculatus | |
| CN106309640A (en) | Chinese herbal medicine preparation for preventing and treating common diseases of factory-bred argopecten irradians | |
| CN106309597A (en) | Chinese herbal medicine preparation for preventing and controlling common diseases of factory-like breeding comb shell | |
| CN106309582A (en) | Chinese herbal medicine preparation for preventing and controlling common diseases of factory-like breeding chlamys farreri | |
| CN106334015A (en) | Chinese herbal medicine preparation for preventing skin fester of industrial culture sebastes schlegeli | |
| CN106266167A (en) | A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Australia Stichopus japonicus Common Diseases | |
| CN106344699A (en) | Traditional Chinese herbal medicine preparation for preventing and treating common diseases of factory-like bred California sea cucumber | |
| CN106334012A (en) | Chinese herbal medicine preparation for preventing common diseases of pond culture haliotis discus hannai | |
| CN106377591A (en) | Chinese herbal medicine preparation for preventing and controlling sepia esculenta skin fester diseases | |
| CN106309668A (en) | Chinese herbal medicine preparation for preventing and controlling common diseases of factory-like breeding solen grandis | |
| CN106389553A (en) | Chinese herbal medicine preparation for controlling common diseases of industrialized bred conches | |
| CN106361810A (en) | Chinese herbal medicine preparation for preventing and treating skin fester diseases of pseudosciaena crocea in industrial aquaculture | |
| CN106377601A (en) | Traditional Chinese herbal medicine preparation for preventing and treating skin ulceration of flatfish cultured in offshore cages |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170222 |