CN106334021A - Chinese herbal medicine preparation for preventing skin fester of industrial culture ruditapes philippinarum - Google Patents

Chinese herbal medicine preparation for preventing skin fester of industrial culture ruditapes philippinarum Download PDF

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CN106334021A
CN106334021A CN201610963843.0A CN201610963843A CN106334021A CN 106334021 A CN106334021 A CN 106334021A CN 201610963843 A CN201610963843 A CN 201610963843A CN 106334021 A CN106334021 A CN 106334021A
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chinese herbal
herbal medicine
medicine preparation
ruditapes philippinarum
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王培亮
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Weihai Hongrun Ocean Technology Co Ltd
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Weihai Hongrun Ocean Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses a Chinese herbal medicine preparation for preventing skin fester of industrial culture ruditapes philippinarum. The Chinese herbal medicine preparation is prepared from, by weight parts, 16-20 parts of radix isatidis, 16-20 parts of gardenia, 12-18 parts of sophora flavescens, 8-12 parts of andrographis paniculata, 12-18 parts of scutellaria baicalensis, 12-18 parts of perilla frutescens, 2-6 parts of honeysuckle, 8-11 parts of dandelion, 2-6 parts of cortex phellodendri and 8-20 parts of radix glycyrrhizae. By utilizing reasonable matching of conventional Chinese herbal medicines, the common disease problem of industrial culture ruditapes philippinarum can be prevented through sterilization, and by adoption of the Chinese herbal medicine preparation, it can be guaranteed that no toxic or harmful chemical agent remains in pond water and the body of ruditapes philippinarum. By use of the Chinese herbal medicine preparation, the skin fester of industrial culture ruditapes philippinarum can be effectively prevented, the survival rate and the spawning rate of industrial culture ruditapes philippinarum are improved, and the Chinese herbal medicine preparation is of great significance for factory breeding of industrial culture ruditapes philippinarum.

Description

A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases
Technical field
The invention belongs to fishery practical technique field, specifically, it is used for preventing and treating plant modification phenanthrene particularly to one kind Chinese herbal and crude drugs preparations of rule guest's curtain clam Common Diseases and preparation method thereof.
Background technology
Philippine curtain clam (scientific name: ruditapes philippinarum): generally also known as mottle clam or Ruditapes philippinarum, Shell is long 2.5-5.7 centimetre.Average 40 millimeters of commercial size.It is a kind of common shell-fish.Shell is firm, equal about valve; Both sides, the beak on shell top is located at first half;Profile is slightly ob-round.Ligament embed, project shell surface, generous brown ellipse Dome-shaped body extends nearly to the half of rear part edge.It is shellfish type seafood, is widely distributed in South China North China Sea Waters, it is given birth to Long rapid, the culture-cycle is short, strong adaptability (extensively warm, wide salt, wide distribution), and out-of-water survival time is long, is that one kind is suitable for manually The excellent shellfish of high-density breeding, is one of Chinese four big cultivated shellfishes.Meat flavour is delicious, nutritious, and protein content is high, ammonia The species composition of base acid and reasonable mixture ratio;Fat content is low, and unrighted acid is higher, easily digested, also respectively Plant vitamin and medicinal ingredient.Multiple trace element needed by human such as calcic, magnesium, iron, zinc, can be used as the nutrition of the mankind, green Color food, is favored by consumer deeply.In clam meat and shellfish mollusk, have what reduce serum cholesterol acted on containing a kind of Dai Ertai 7- cholesterol and 24- methylene cholesterol, they have suppression cholesterol concurrently and in liver synthesis and accelerate excretion of cholesterol Unique effect so that internal cholesterol declines.Their effect is more higher than the medicine sitosterol of conventional norcholesterol.Comprehensive Upper described, Philippine curtain clam is a kind of high protein of high-quality, low-fat food, and it is of high nutritive value, delicious flavour, has good Market prospects and value of exploiting and utilizing.
In recent years, China's Coastal Areas cultivated shellfish massive mortality event frequently occurs, the shellfish kind being related to and support Grow area and scope is continuously increased, make shellfishery suffer great economic loss.Cultivated shellfish massive mortality problem is Cause the extensive attention at aquaculture family.The cultivated shellfish bionosis cause of death, mainly has: virus, bacterium, parasitism are former Worm, rickettsia-like organism, class Chlamydia, mycoplasma-like organism(MLO) etc..
Chinese herbal medicine belongs to natural drug, in application and the research of China, has accumulated rich experience.Using Chinese herbal medicine Preventing and treating plant modification Philippine curtain clam Common Diseases are increasingly subject to attention and the favor of people, are increasingly widely accepted, are The mechanism of action unique with it, the mode of action and advantage are inseparable, put it briefly, and herbal control disease has adjustment and makees With, strengthening vital QI to eliminate pathogenic factors, have no drug resistance and the incomparable feature of other medicines and the advantage such as nuisanceless, effect is good, and does not deposit In the residue problem of antibiotic medicine, products export is bred to the aquatic products of China highly beneficial.In addition, Chinese herbal medicine also has price just Preferably, wide material sources, the advantages of easy to use, are one of developing direction of fish medicine from now on.
Content of the invention
It is an object of the invention to provide a kind of Chinese herbal medicine for preventing and treating plant modification Philippine curtain clam Common Diseases Preparation.
The object of the present invention is achieved like this:
A kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases, by following weight portion Medicinal material is prepared from: Radix Isatidis 16-20 part, cape jasmine 16-20 part, kuh-seng 12-18, Herba Andrographitis 8-12 part, root of large-flowered skullcap 12-18 part, purple Soviet Union's 12-18 part, honeysuckle 2-6 part, dandelion 8-11 part, golden cypress 2-6 part, Radix Glycyrrhizae 8-20 part.
Preferably, the described Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases, by as follows The Chinese medicine of weight portion is prepared from: 18 parts of Radix Isatidis, 18 parts of cape jasmine, kuh-seng 16,10 parts of Herba Andrographitis, 16 parts of the root of large-flowered skullcap, purple perilla 14 Part, 4 parts of honeysuckle, 9 parts of dandelion, 4 parts of golden cypress, 11 parts of Radix Glycyrrhizae.
It is further preferred that the described Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases is Granule.
The preparation method of the Chinese herbal and crude drugs preparations that above-mentioned each Chinese medicine preparation cost is invented, comprises the steps:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh the above-mentioned Chinese medicine cleaning up by recipe quantity, pulverize, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
The consumption of above-mentioned preventing and treating plant modification Philippine curtain clam Common Diseases Chinese herbal granules is by 60-80g/100kg The ratio of body weight mixes pharmaceutical chemistry, allows plant modification Philippine curtain clam to be administered orally, and being used in conjunction 5-7 days is a course for the treatment of.
The present inventor prevents and treats plant modification Philippine curtain clam Common Diseases with Chinese herbal and crude drugs preparations, from our experimental result See, application the present invention Chinese herbal and crude drugs preparations can effective control plant modification Philippine curtain clam Common Diseases, reduce batch production numerous Educate the M & M of Philippine's curtain clam Common Diseases, but also do not produce drug resistance.The present invention is reasonable by traditional Chinese medicine Prescription, anti-inflammation, strengthen immunity effect extremely notable, be that aquatic products is bred industry and provided a kind of plant modification Philippine The effectively treatment medicine of curtain clam Common Diseases, has the characteristics that instant effect, curative effect really, no drug residue, without any side effects;Its Preparation method is simple, the needs of suitable large-scale production.
Specific embodiment
Further illustrate the present invention below by embodiment.Embodiments of the invention are only used for the present invention is described, and It is not limitation of the present invention, under the concept thereof of the present invention, the present invention is broadly fallen into the simple modifications of preparation method of the present invention Claimed scope.With reference to specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese herbal granules of preventing and treating plant modification Philippine curtain clam Common Diseases, by Radix Isatidis, cape jasmine, kuh-seng, Herba Andrographitis, the root of large-flowered skullcap, purple perilla, honeysuckle, dandelion, golden cypress, Radix Glycyrrhizae composition, wherein, Radix Isatidis 18kg, cape jasmine 18kg, kuh-seng 16kg, Herba Andrographitis 10kg, root of large-flowered skullcap 16kg, purple perilla 14kg, honeysuckle 4kg, dandelion 9kg, golden cypress 4kg, Radix Glycyrrhizae 11kg.
The preparation method of the Chinese herbal granules of above-mentioned preventing and treating plant modification Philippine curtain clam Common Diseases, concrete preparation step Suddenly as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh clear Radix Isatidis 18kg, cape jasmine 18kg, kuh-seng 16kg, Herba Andrographitis 10kg, root of large-flowered skullcap 16kg, purple perilla 14kg, honeysuckle 4kg, dandelion 9kg, golden cypress 4kg, Radix Glycyrrhizae 11kg are raw material, and wash clean Chinese medicine is pulverized, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
Embodiment 2
A kind of Chinese herbal granules of preventing and treating plant modification Philippine curtain clam Common Diseases, by Radix Isatidis, cape jasmine, kuh-seng, Herba Andrographitis, the root of large-flowered skullcap, purple perilla, honeysuckle, dandelion, golden cypress, Radix Glycyrrhizae composition, wherein, Radix Isatidis 19kg, cape jasmine 17kg, kuh-seng 15kg, Herba Andrographitis 9kg, root of large-flowered skullcap 14kg, purple perilla 13kg, honeysuckle 3kg, dandelion 10kg, golden cypress 5kg, Radix Glycyrrhizae 13kg.
The preparation method of the Chinese herbal granules of above-mentioned preventing and treating plant modification Philippine curtain clam Common Diseases, concrete preparation step Suddenly as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh Radix Isatidis 19kg, cape jasmine 17kg, kuh-seng 15kg, Herba Andrographitis 9kg, root of large-flowered skullcap 14kg, purple perilla 13kg, Honeysuckle 3kg, dandelion 10kg, golden cypress 5kg, Radix Glycyrrhizae 13kg are raw material, and wash clean Chinese medicine is pulverized, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
Embodiment 3
A kind of Chinese herbal granules of preventing and treating plant modification Philippine curtain clam Common Diseases, by Radix Isatidis, cape jasmine, kuh-seng, Herba Andrographitis, the root of large-flowered skullcap, purple perilla, honeysuckle, dandelion, golden cypress, Radix Glycyrrhizae composition, wherein, Radix Isatidis 20kg, cape jasmine 20kg, kuh-seng 18kg, Herba Andrographitis 12kg, root of large-flowered skullcap 18kg, purple perilla 18kg, honeysuckle 6kg, dandelion 11kg, golden cypress 6kg, Radix Glycyrrhizae 15kg.
The preparation method of the Chinese herbal granules of above-mentioned preventing and treating plant modification Philippine curtain clam Common Diseases, concrete preparation step Suddenly as follows:
The first step, preparation clear cream powder:
1) get the raw materials ready: weigh Radix Isatidis 19kg, cape jasmine 17kg, kuh-seng 15kg, Herba Andrographitis 9kg, root of large-flowered skullcap 14kg, purple perilla 13kg, Honeysuckle 3kg, dandelion 10kg, golden cypress 5kg, Radix Glycyrrhizae 15kg are raw material, and wash clean Chinese medicine is pulverized, standby;
2) decoct: add water to cook, first decocts 8 times that every tank adds water as medicinal material total amount, keeps 2 hours, carry after ebuillition of heated Take liquid to filter through 200 mesh filters and enter settling tank;Second water decocting 6 times of medicinal material amount of addition heating extraction, protects boiling 1.5 little When, extract filters through 200 mesh filters and enters settling tank;
3) precipitate: extract liquid precipitate 12 hours in settling tank, extract supernatant and filter through 200 mesh filters and steam to triple effect Send out in device, sediment presses offal treatment;
4) concentrate: when supernatant is concentrated into relative density for 1.05~1.10 (40 DEG C of mensure) in triple effect evaporator, Dilute clear cream 200 mesh filter is filtered in suction vacuum decompressioning and concentrating tank, adds ethanol to alcohol content 60% (v/v), place, Filtration;Concentrating and mix to relative density is to go out cream when 1.10~1.22 (90 DEG C of mensure), to storage cream bucket, standby;
5) it is dried: wherein vacuum: 0.01mpa, temperature: 78~82 DEG C, 12~18 hours drying times;
6) beat powder: smashing fineness 80 mesh sieve, obtain clear cream powder;
Second step, according to clear cream powder: starch: 55% ethanol is that the weight ratio of 1:1~3:0.1~0.3 weighs clear cream powder, paste Essence and 55% ethanol, wherein 55% ethanol refers to the ethanol water that volumetric concentration is 55%;
3rd step, clear cream powder and starch is put in trough type mixing machine, stirs 20 minutes, be slowly added into 55% while stirring Ethanol, to making softwood, with 12 mesh stainless steel sieve series grains, 60~70 DEG C of dryings 2 hours, take out, cool and obtain final product described particle Agent.
Embodiment 4 clinical testing
The consumption of the Chinese herbal granules of above-mentioned preventing and treating plant modification Philippine curtain clam Common Diseases is by 60g/100kg body The ratio of weight mixes pharmaceutical chemistry, is administered orally, and being used in conjunction 5 days is a course for the treatment of.Reach the purpose for the treatment of disease by intestinal absorption after oral.
On July 20th, 2016, the plant modification Philippine curtain clam morbidity that Shandong Province Weihai City nursery is bred, face Bed symptom: the plant modification Philippine curtain clam tentacle of illness, trunk or skin of head fester, and necrosis comes off, severe patient is burst Rotten it is deep into muscle layer.It is typical ulcer disease after diagnosing.Then Chinese herbal granules treatment, medication 2 days described in the embodiment of the present invention 2 are used Afterwards, the state of an illness is clearly better, and substantially, the death rate reduces body color change by sky, and after 7 days, the death rate is 0, is almost recovered.
Inventor prevents and treats plant modification Philippine curtain clam Common Diseases with Chinese herbal and crude drugs preparations, from our experimental result See, no matter being prevention, or treatment, evident in efficacy, but also do not produce drug resistance, promoting through test of many times and small area should With achieving good effect, so that breeding field economic benefit is significantly improved.

Claims (3)

1. a kind of Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases it is characterised in that: by as follows The Chinese medicine of weight portion is prepared from: Radix Isatidis 16-20 part, cape jasmine 16-20 part, kuh-seng 12-18, Herba Andrographitis 8-12 part, the root of large-flowered skullcap 12-18 part, purple perilla 12-18 part, honeysuckle 2-6 part, dandelion 8-11 part, golden cypress 2-6 part, Radix Glycyrrhizae 8-20 part.
2. the Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases according to claim 1, its Be characterised by: be prepared from by the Chinese medicine of following weight portion: 18 parts of Radix Isatidis, 18 parts of cape jasmine, kuh-seng 16,10 parts of Herba Andrographitis, 16 parts of the root of large-flowered skullcap, 14 parts of purple perilla, 4 parts of honeysuckle, 9 parts of dandelion, 4 parts of golden cypress, 11 parts of Radix Glycyrrhizae.
3. the Chinese herbal and crude drugs preparations for preventing and treating plant modification Philippine curtain clam Common Diseases according to claim 1 and 2, It is characterized in that: it is granule.
CN201610963843.0A 2016-11-04 2016-11-04 Chinese herbal medicine preparation for preventing skin fester of industrial culture ruditapes philippinarum Withdrawn CN106334021A (en)

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Application publication date: 20170118