CN106110334B - 一种表面功能化可载药洗脱微球的制备方法 - Google Patents
一种表面功能化可载药洗脱微球的制备方法 Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
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Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
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CN201610650166.7A CN106110334B (zh) | 2016-08-08 | 2016-08-08 | 一种表面功能化可载药洗脱微球的制备方法 |
KR1020187007546A KR102083023B1 (ko) | 2016-08-08 | 2016-11-04 | 표면 기능화된 약물 운반 가능한 용출 마이크로스피어의 제조 방법 |
PCT/CN2016/104511 WO2018028058A1 (zh) | 2016-08-08 | 2016-11-04 | 一种表面功能化可载药洗脱微球的制备方法 |
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CN201610650166.7A CN106110334B (zh) | 2016-08-08 | 2016-08-08 | 一种表面功能化可载药洗脱微球的制备方法 |
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CN106110334A CN106110334A (zh) | 2016-11-16 |
CN106110334B true CN106110334B (zh) | 2019-11-15 |
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KR (1) | KR102083023B1 (ko) |
CN (1) | CN106110334B (ko) |
WO (1) | WO2018028058A1 (ko) |
Families Citing this family (9)
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CN108264612B (zh) * | 2018-02-25 | 2020-10-09 | 温岭汉德高分子科技有限公司 | 一种用于单晶硅制绒的壳聚糖-聚2-丙烯酰胺基-2-甲基丙磺酸钠共聚物的制备方法 |
CN109464702B (zh) * | 2019-01-14 | 2021-02-26 | 浙江瑞谷生物科技有限公司 | 含bmp-2的牙槽骨修复材料及其制备方法和应用 |
DE102019107633A1 (de) | 2019-03-25 | 2020-10-29 | Sphera Technology Gmbh | Mehrkomponentensystem und Verfahren zur Herstellung eines Mehrkomponentensystems |
CN110508259B (zh) * | 2019-09-03 | 2022-02-15 | 晋江瑞碧科技有限公司 | 一种铜离子印迹复合磁性中空微球的制备方法 |
CN112168787B (zh) * | 2020-09-24 | 2023-03-24 | 山东瑞安泰医疗技术有限公司 | 一种功能化可降解药物洗脱微球及其制备方法 |
DE102020124955A1 (de) | 2020-09-24 | 2022-03-24 | Sphera Technology Gmbh | Elektronikeinheit mit einem integrierten Schaltkreis und Verfahren zu deren Herstellung |
CN112316199B (zh) * | 2020-11-16 | 2022-02-22 | 江南大学 | 一种改性羧甲基壳聚糖微球及其制备方法和应用 |
CN114191410A (zh) * | 2021-11-15 | 2022-03-18 | 深圳北航新兴产业技术研究院 | 一种诊疗一体化双亲微球缓释微球的制备方法 |
CN114481616A (zh) * | 2022-03-11 | 2022-05-13 | 四川三联新材料有限公司 | 一种加热卷烟用壳聚糖基膜复合材料的制备方法 |
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CN104258474A (zh) * | 2014-10-15 | 2015-01-07 | 江南大学 | 一种含有离子交换功能基团的栓塞微球 |
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- 2016-08-08 CN CN201610650166.7A patent/CN106110334B/zh active Active
- 2016-11-04 WO PCT/CN2016/104511 patent/WO2018028058A1/zh active Application Filing
- 2016-11-04 KR KR1020187007546A patent/KR102083023B1/ko active IP Right Grant
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Also Published As
Publication number | Publication date |
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KR20180057622A (ko) | 2018-05-30 |
WO2018028058A1 (zh) | 2018-02-15 |
CN106110334A (zh) | 2016-11-16 |
KR102083023B1 (ko) | 2020-02-28 |
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