CN105768071A - 一种水溶姜黄粉末制备方法 - Google Patents
一种水溶姜黄粉末制备方法 Download PDFInfo
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Abstract
本发明公开了一种水溶姜黄粉末制备方法。所述方法以壁材、填充剂、酸度调节剂和水经搅拌、水浴制成水相，将姜黄晶体、抗氧化剂、乳化助剂溶于水相后进行乳化，乳化后的乳液经研磨、喷雾、干燥后得到水溶性姜黄粉末。所述方法包括以下步骤：制作水相、乳化、研磨、喷雾干燥、指标检测。通过所述方法制得的姜黄粉末水分散性好，粒径可达到纳米级别，可以应用在保健品中。
Description
技术领域
本发明属于植物色素提取技术领域，具体涉及一种水溶姜黄粉末制备方法。
背景技术
姜黄来源于姜科植物姜黄的干燥根茎，主要产于我国四川、云南、广西、广东、福建、台湾等地。姜黄性温，味辛、苦，具有破血行气、通经止痛的作用，常用于治疗胸胁刺痛、闭经、瘕、风湿肩臂疼痛、跌扑肿痛等。姜黄的化学成分包括姜黄素类化合物、萜类化合物、甾醇类化合物、糖类化合物及微量元素等。其中姜黄素类化合物主要包括姜黄素、去甲氧基姜黄素和双去甲氧基姜黄素。
姜黄素是从姜黄的根茎中提取精制而得的一种黄色、粉末状天然食用色素，其色泽鲜艳、着色力强、稳定性好、安全无毒。它具有解毒、生肌、止血、降血脂、降胆固醇、抗动脉粥样硬化，利胆并促进胆汁生成分泌等药理作用。
姜黄素可广泛应用于饮料、冷饮、糕点、酒类、糖果、果冻、布丁、肉制品、米面制品及奶油等产品中。
姜黄素为醇溶性二苯基庚烃类化合物，不溶于冷水，微溶于乙醚和苯，加热时溶于乙醇、乙二醇，易溶于冰醋酸和碱溶液。姜黄素在高温、强酸、强碱或强光环境中稳定性较差，因此提取温度不宜过高。目前，其主要提取方法有甲醇、乙醇有机溶剂提取法、碱水热提法、酶解提取法、外场辅助提取法等。
提取姜黄素的方法多种多样，各具特色，但总的来说分为提取和精制两大步骤。姜黄中姜黄素的提取方法主要有乙醇回流法、水杨酸钠法、酸碱法、活性炭吸附法、大孔树脂法等。工业上常用乙醇回流法制取姜黄素，但使用乙醇浓度为80%，乙醇浓度高，提取时间长。酸碱法虽然成本较低，但总姜黄素溶液在碱性条件下分解，并且随着碱性增强，分解速度加快，在生产过程中很难解决姜黄素分解的问题，这样生产出的总姜黄素的质量就不稳定。水杨酸钠法制得的姜黄素纯度较高，但是姜黄素的转移率不到10%，产率太低。活性炭吸附法制得的总姜黄素的含量和转移率都较低，因为活性炭的吸附能力太强，不易洗脱。大孔树脂法，即采用乙醇提取，药液过大孔树脂除杂的方法制备总姜黄素，所得产品的纯度可达65%，转移率不低于60%，但是该方法工艺复杂，设备要求较高，产品纯度相对较低。
另外，上述现有的姜黄素制备工艺具有以下不足：一是反应时间长，制备效率低；二是工艺过程较复杂；三是所得产品的品质不够高，水溶性不够好，产品颗粒度较大。
发明内容
为了克服现有的提取姜黄素方法存在的反应时间长、工艺过程较复杂等问题，本发明提供一种水溶姜黄粉末制备方法。通过所述方法制得的姜黄粉末水分散性好，粒径可以达到纳米级别，可以应用在保健品中。
为实现上述目标，本发明采用以下技术方案：
一种水溶姜黄粉末制备方法，所述方法以壁材、填充剂、酸度调节剂和水经搅拌、水浴制成水相，将姜黄晶体、抗氧化剂、乳化助剂溶于水相后进行乳化，乳化后的乳液经研磨、喷雾、干燥后得到水溶性姜黄粉末。
所述壁材是物理变性淀粉、γ-环糊精、辛烯基琥珀酸淀粉钠。
所述填充剂是麦芽糊精、葡萄糖浆、葡萄糖。
所述酸度调节剂是维生素C和柠檬酸。
优选地，所述抗氧化剂是抗坏血酸钠棕榈酸酯，所述乳化助剂是丙二醇。
所述各组分的质量份数是：姜黄晶体:壁材:填充剂:酸度调节剂:水:抗氧化剂:乳化助剂=5～6:35～40:35～40:1～2:150～200:1～2:3～4。
一种水溶姜黄粉末的制备方法，所述方法包括以下步骤：
1）制作水相：按照质量份数35～40:35～40:1～2:150～200，将壁材、填充剂、酸度调节剂和水加入反应器中，搅拌后放入水浴锅中，水浴温度为75℃-85℃，直至水相溶解，然后将水相冷却至室温，备用；
2）乳化：按照质量份数5～6:1～2:3～4，将姜黄晶体、抗氧化剂和乳化助剂加入水相中，搅拌均匀后放置于高速乳化机下进行乳化，乳化转速保持为6000-6500r/min，乳化时间为15-20min；
3）研磨：将乳化后的乳液用研磨机进行研磨，研磨转速保持为2500-3000r/min，研磨时间为6-8h；
4）喷雾干燥：将研磨完成后的乳液经喷雾和干燥得到水溶姜黄粉末，喷雾干燥设备的进风温度为180℃-200℃，出风温度为80℃-90℃；
5）指标检测：检测姜黄粉末的色价、粒径和溶剂残留量。
色价检测方法：采用分光光度计检测姜黄粉末的色价，分别检测在全水中以及先在全水中溶解然后再在95％乙醇中溶解后的吸光度值，最大吸收波长为425nm。
粒径检测方法：使用激光粒度分析仪进行粒度测定。
溶剂残留量检测方法：采用气相色谱测定溶剂残留量。
本发明的优点和有益效果为：通过本发明所述的一种水溶姜黄粉末制备方法，制得的姜黄粉末水分散性好，粒径可以达到纳米级别，溶剂残留量在100ppm左右，可以应用在保健品中。
附图说明
下面结合附图和实施例对本发明作进一步说明。
图1为本发明所述一种水溶姜黄粉末制备方法的工艺流程图。
具体实施方式
实施例1
参见图1，工艺过程如下：
1）制作水相：称取物理变性淀粉130g、麦芽糊精185g、葡萄糖浆24g、葡萄糖12.5g、维生素C6g、柠檬酸2g、γ-环糊精60g、辛烯基琥珀酸淀粉钠30g、水1000g，加入到2L烧杯中，搅拌后，将烧杯放入水浴锅中，保持温度80℃，直至水相溶解，冷却至室温，备用；
2）乳化：分别称取92％姜黄晶体28g、抗坏血酸钠棕榈酸酯5g、乳化助剂丙二醇20g、倒入水相之中，搅拌均匀后，将烧杯放置于高速乳化机下进行乳化，乳化转速保持6400r/min，乳化时间保持15-20min；
3）研磨：将乳化后的乳液用研磨机进行研磨，研磨转速2500r/min，研磨时间为7小时；
4）喷雾干燥：将研磨完成后的乳液经喷雾干燥得到水溶姜黄粉末，喷雾干燥设备的进风温度为195℃，出风温度为85℃；
5）指标检测：检测姜黄粉末的色价、粒径和溶剂残留量。
最后应说明的是：显然，上述实施例仅仅是为清楚地说明本发明所作的举例，而并非对实施方式的限定。对于所属领域的普通技术人员来说，在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无需也无法对所有的实施方式予以穷举。而由此所引伸出的显而易见的变化或变动仍处于本发明的保护范围之中。
Claims (8)
1.一种水溶姜黄粉末制备方法，其特征在于：所述方法以壁材、填充剂、酸度调节剂和水经搅拌、水浴制成水相，将姜黄晶体、抗氧化剂、乳化助剂溶于水相后进行乳化，乳化后的乳液经研磨、喷雾、干燥后得到水溶性姜黄粉末。
2.如权利要求1所述的一种水溶姜黄粉末制备方法，其特征在于：所述壁材可以是物理变性淀粉、γ-环糊精、辛烯基琥珀酸淀粉钠。
3.如权利要求1所述的一种水溶姜黄粉末制备方法，其特征在于：所述填充剂是麦芽糊精、葡萄糖浆、葡萄糖。
4.如权利要求1所述的一种水溶姜黄粉末制备方法，其特征在于：所述酸度调节剂是维生素C和柠檬酸。
5.如权利要求1所述的一种水溶姜黄粉末制备方法，其特征在于：所述抗氧化剂是抗坏血酸钠棕榈酸酯，所述乳化助剂是丙二醇。
6.如权利要求1所述的一种水溶姜黄粉末制备方法，其特征在于：所述各组分的质量份数是：姜黄晶体:壁材:填充剂:酸度调节剂:水:抗氧化剂:乳化助剂=5～6:35～40:35～40:1～2:150～200:1～2:3～4。
7.如权利要求1所述的一种水溶姜黄粉末制备方法，其特征在于，所述方法包括以下步骤：
1）制作水相：按照质量份数35～40:35～40:1～2:150～200，将壁材、填充剂、酸度调节剂和水加入反应器中，搅拌后放入水浴锅中，水浴温度为75℃-85℃，直至水相溶解，然后将水相冷却至室温，备用；
2）乳化：按照质量份数5～6:1～2:3～4，将姜黄晶体、抗氧化剂和乳化助剂加入水相中，搅拌均匀后放置于高速乳化机下进行乳化，乳化转速保持为6000-6500r/min，乳化时间为15-20min；
3）研磨：将乳化后的乳液用研磨机进行研磨，研磨转速保持为2500-3000r/min，研磨时间为6-8h；
4）喷雾干燥：将研磨完成后的乳液经喷雾和干燥得到水溶姜黄粉末，喷雾干燥设备的进风温度为180℃-200℃，出风温度为80℃-90℃；
5）指标检测：检测姜黄粉末的色价、粒径和溶剂残留量。
8.如权利要求1或7所述的一种水溶姜黄粉末制备方法，其特征在于，所述步骤5）中的指标检测方法是：采用分光光度计检测姜黄粉末的色价，分别检测在全水中以及先在全水中溶解然后再在95％乙醇中溶解后的吸光度值，最大吸收波长为425nm；使用激光粒度分析仪进行粒度测定；采用气相色谱测定溶剂残留量。
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