CN105744952A - 病毒疫苗及其制备方法 - Google Patents

病毒疫苗及其制备方法 Download PDF

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Publication number
CN105744952A
CN105744952A CN201480050520.1A CN201480050520A CN105744952A CN 105744952 A CN105744952 A CN 105744952A CN 201480050520 A CN201480050520 A CN 201480050520A CN 105744952 A CN105744952 A CN 105744952A
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CN
China
Prior art keywords
virus
stock solution
inactivation
purification
encephalitis
Prior art date
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Pending
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CN201480050520.1A
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English (en)
Chinese (zh)
Inventor
克里什纳·莫汉·瓦德雷夫
文卡特桑·拉马沙米
普拉桑纳·库马尔·杜夫鲁
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Bharat Biotech International Ltd
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Bharat Biotech International Ltd
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Filing date
Publication date
Application filed by Bharat Biotech International Ltd filed Critical Bharat Biotech International Ltd
Publication of CN105744952A publication Critical patent/CN105744952A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24151—Methods of production or purification of viral material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201480050520.1A 2013-09-14 2014-09-08 病毒疫苗及其制备方法 Pending CN105744952A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN4135/CHE/2013 2013-09-14
PCT/IN2014/000585 WO2015059714A1 (en) 2013-09-14 2014-09-08 Emergency mode in a hybrid vehicle
IN4135CH2013 IN2013CH04135A (enExample) 2013-09-14 2014-09-08

Publications (1)

Publication Number Publication Date
CN105744952A true CN105744952A (zh) 2016-07-06

Family

ID=52997726

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480050520.1A Pending CN105744952A (zh) 2013-09-14 2014-09-08 病毒疫苗及其制备方法

Country Status (6)

Country Link
CN (1) CN105744952A (enExample)
AU (1) AU2014338520B2 (enExample)
IN (1) IN2013CH04135A (enExample)
PH (1) PH12016500500A1 (enExample)
RU (1) RU2706693C2 (enExample)
WO (1) WO2015059714A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111394321A (zh) * 2020-03-30 2020-07-10 无锡加莱克色谱科技有限公司 病毒颗粒纯化用超大孔径层析介质及其应用方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CA2992531C (en) * 2015-07-16 2023-09-26 Bharat Biotech International Limited Vaccine compositions
US11162880B2 (en) 2015-11-09 2021-11-02 University Of Notre Dame Du Lac Particle size purification method and devices
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
CA3081581A1 (en) 2017-11-03 2019-05-09 Takeda Vaccines, Inc. Method for inactivating zika virus and for determining the completeness of inactivation
SG11202004863QA (en) 2017-11-30 2020-06-29 Takeda Vaccines Inc Zika vaccines and immunogenic compositions, and methods of using the same
EP3581646A1 (en) * 2018-06-15 2019-12-18 Themis Bioscience GmbH Integrated manufacturing and chromatographic system for virus production
JP7228675B2 (ja) 2018-08-16 2023-02-24 イー・エム・デイー・ミリポア・コーポレイシヨン 閉鎖バイオプロセシングデバイス

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1272879A (zh) * 1997-08-28 2000-11-08 第一制糖株式会社 一种适应非洲绿猴肾细胞的减毒的日本脑炎病毒以及日本脑炎疫苗
CN102100910B (zh) * 2009-12-21 2013-01-23 北京清大天一科技有限公司 一种生产病毒疫苗的方法
CN103228293A (zh) * 2010-11-30 2013-07-31 巴拉特生物技术国际有限公司 用于在哺乳动物中预防和治疗金迪普拉病毒感染的疫苗制剂

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* Cited by examiner, † Cited by third party
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WO2010137036A2 (en) * 2009-05-25 2010-12-02 Panacea Biotec Ltd Novel japanese encephalitis vaccine and method of manufacturing the same
US9580692B2 (en) * 2012-02-29 2017-02-28 Ge Healthcare Bioprocess R&D Ab Method for endotoxin removal

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1272879A (zh) * 1997-08-28 2000-11-08 第一制糖株式会社 一种适应非洲绿猴肾细胞的减毒的日本脑炎病毒以及日本脑炎疫苗
CN102100910B (zh) * 2009-12-21 2013-01-23 北京清大天一科技有限公司 一种生产病毒疫苗的方法
CN103228293A (zh) * 2010-11-30 2013-07-31 巴拉特生物技术国际有限公司 用于在哺乳动物中预防和治疗金迪普拉病毒感染的疫苗制剂

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A.V. JAMGAONKAR等: "SEROLOGICAL EVIDENCE FOR JAPANESE ENCEPHALITIS VIRUS AND WEST NILE VIRUS INFECTIONS IN WATER FREQUENTING AND TERRESTRIAL WILD BIRDS IN KOLAR DISTRICT, KARNATAKA STATE, INDIA. A RETROSPECTIVE STUDY", 《ACTA VIROLOGICA》 *
ANIT SINGH等: "A Japanese Encephalitis Vaccine From India Induces Durable and Cross-protective Immunity Against Temporally and Spatially Wide-ranging Global Field Strains", 《JID》 *
DRANIT SINGH等: "CTRI/2011/07/001855", 《CTRI》 *
HIROKO TORINIWA等: "Long-term stability of Vero cell-derived inactivated Japanese encephalitis vaccine prepared using serum-free medium", 《VACCINE》 *
N KEDARNATH等: "Isolation of Japanese Encephalitis & West Nile Viruses From Peripheral Blood of Encephalitis Patients", 《INDIAN J MED RES.》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111394321A (zh) * 2020-03-30 2020-07-10 无锡加莱克色谱科技有限公司 病毒颗粒纯化用超大孔径层析介质及其应用方法

Also Published As

Publication number Publication date
WO2015059714A1 (en) 2015-04-30
PH12016500500A1 (en) 2016-06-13
AU2014338520A1 (en) 2016-03-31
IN2013CH04135A (enExample) 2015-08-14
AU2014338520B2 (en) 2019-12-05
RU2016114285A (ru) 2017-10-19
RU2016114285A3 (enExample) 2018-07-16
WO2015059714A8 (en) 2015-06-18
RU2706693C2 (ru) 2019-11-20

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