CN105744952A - 病毒疫苗及其制备方法 - Google Patents

病毒疫苗及其制备方法 Download PDF

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Publication number
CN105744952A
CN105744952A CN201480050520.1A CN201480050520A CN105744952A CN 105744952 A CN105744952 A CN 105744952A CN 201480050520 A CN201480050520 A CN 201480050520A CN 105744952 A CN105744952 A CN 105744952A
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CN
China
Prior art keywords
virus
stock solution
inactivation
purification
encephalitis
Prior art date
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Pending
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CN201480050520.1A
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English (en)
Chinese (zh)
Inventor
克里什纳·莫汉·瓦德雷夫
文卡特桑·拉马沙米
普拉桑纳·库马尔·杜夫鲁
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Bharat Biotech International Ltd
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Bharat Biotech International Ltd
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Publication date
Application filed by Bharat Biotech International Ltd filed Critical Bharat Biotech International Ltd
Publication of CN105744952A publication Critical patent/CN105744952A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24151—Methods of production or purification of viral material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201480050520.1A 2013-09-14 2014-09-08 病毒疫苗及其制备方法 Pending CN105744952A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN4135/CHE/2013 2013-09-14
PCT/IN2014/000585 WO2015059714A1 (en) 2013-09-14 2014-09-08 Emergency mode in a hybrid vehicle
IN4135CH2013 IN2013CH04135A (cg-RX-API-DMAC7.html) 2013-09-14 2014-09-08

Publications (1)

Publication Number Publication Date
CN105744952A true CN105744952A (zh) 2016-07-06

Family

ID=52997726

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480050520.1A Pending CN105744952A (zh) 2013-09-14 2014-09-08 病毒疫苗及其制备方法

Country Status (6)

Country Link
CN (1) CN105744952A (cg-RX-API-DMAC7.html)
AU (1) AU2014338520B2 (cg-RX-API-DMAC7.html)
IN (1) IN2013CH04135A (cg-RX-API-DMAC7.html)
PH (1) PH12016500500A1 (cg-RX-API-DMAC7.html)
RU (1) RU2706693C2 (cg-RX-API-DMAC7.html)
WO (1) WO2015059714A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111394321A (zh) * 2020-03-30 2020-07-10 无锡加莱克色谱科技有限公司 病毒颗粒纯化用超大孔径层析介质及其应用方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3322441A4 (en) * 2015-07-16 2018-12-19 Bharat Biotech International Limited Vaccine compositions
WO2017083286A1 (en) 2015-11-09 2017-05-18 University Of Notre Dame Particle size purification method and devices
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
KR20200117981A (ko) 2017-11-03 2020-10-14 다케다 백신즈 인코포레이티드 지카 백신 및 면역원성 조성물, 그리고 이를 이용하는 방법들
MX2020005554A (es) 2017-11-30 2020-10-12 Takeda Vaccines Inc Vacunas y composiciones inmunogenas para zika y metodos para usarlas.
EP3581646A1 (en) * 2018-06-15 2019-12-18 Themis Bioscience GmbH Integrated manufacturing and chromatographic system for virus production
US12172108B2 (en) 2018-08-16 2024-12-24 Emd Millipore Corporation Closed bioprocessing device

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1272879A (zh) * 1997-08-28 2000-11-08 第一制糖株式会社 一种适应非洲绿猴肾细胞的减毒的日本脑炎病毒以及日本脑炎疫苗
CN102100910B (zh) * 2009-12-21 2013-01-23 北京清大天一科技有限公司 一种生产病毒疫苗的方法
CN103228293A (zh) * 2010-11-30 2013-07-31 巴拉特生物技术国际有限公司 用于在哺乳动物中预防和治疗金迪普拉病毒感染的疫苗制剂

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* Cited by examiner, † Cited by third party
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KR20120027381A (ko) * 2009-05-25 2012-03-21 파나세아 바이오테크 리미티드 일본뇌염 백신 및 그것의 제조 방법
US9580692B2 (en) * 2012-02-29 2017-02-28 Ge Healthcare Bioprocess R&D Ab Method for endotoxin removal

Patent Citations (3)

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CN1272879A (zh) * 1997-08-28 2000-11-08 第一制糖株式会社 一种适应非洲绿猴肾细胞的减毒的日本脑炎病毒以及日本脑炎疫苗
CN102100910B (zh) * 2009-12-21 2013-01-23 北京清大天一科技有限公司 一种生产病毒疫苗的方法
CN103228293A (zh) * 2010-11-30 2013-07-31 巴拉特生物技术国际有限公司 用于在哺乳动物中预防和治疗金迪普拉病毒感染的疫苗制剂

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A.V. JAMGAONKAR等: "SEROLOGICAL EVIDENCE FOR JAPANESE ENCEPHALITIS VIRUS AND WEST NILE VIRUS INFECTIONS IN WATER FREQUENTING AND TERRESTRIAL WILD BIRDS IN KOLAR DISTRICT, KARNATAKA STATE, INDIA. A RETROSPECTIVE STUDY", 《ACTA VIROLOGICA》 *
ANIT SINGH等: "A Japanese Encephalitis Vaccine From India Induces Durable and Cross-protective Immunity Against Temporally and Spatially Wide-ranging Global Field Strains", 《JID》 *
DRANIT SINGH等: "CTRI/2011/07/001855", 《CTRI》 *
HIROKO TORINIWA等: "Long-term stability of Vero cell-derived inactivated Japanese encephalitis vaccine prepared using serum-free medium", 《VACCINE》 *
N KEDARNATH等: "Isolation of Japanese Encephalitis & West Nile Viruses From Peripheral Blood of Encephalitis Patients", 《INDIAN J MED RES.》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111394321A (zh) * 2020-03-30 2020-07-10 无锡加莱克色谱科技有限公司 病毒颗粒纯化用超大孔径层析介质及其应用方法

Also Published As

Publication number Publication date
WO2015059714A1 (en) 2015-04-30
PH12016500500A1 (en) 2016-06-13
AU2014338520A1 (en) 2016-03-31
RU2016114285A (ru) 2017-10-19
IN2013CH04135A (cg-RX-API-DMAC7.html) 2015-08-14
RU2016114285A3 (cg-RX-API-DMAC7.html) 2018-07-16
RU2706693C2 (ru) 2019-11-20
WO2015059714A8 (en) 2015-06-18
AU2014338520B2 (en) 2019-12-05

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