CN1056618C - 酰化的胰岛素和含有这种胰岛素的药物组合物 - Google Patents

酰化的胰岛素和含有这种胰岛素的药物组合物 Download PDF

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Publication number
CN1056618C
CN1056618C CN94193852A CN94193852A CN1056618C CN 1056618 C CN1056618 C CN 1056618C CN 94193852 A CN94193852 A CN 94193852A CN 94193852 A CN94193852 A CN 94193852A CN 1056618 C CN1056618 C CN 1056618C
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China
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human insulin
ala
glu
insulin
gly
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Expired - Lifetime
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CN94193852A
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Chinese (zh)
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CN1133598A (zh
Inventor
S·哈夫仑德
J·B·哈斯塔姆
I·乔那森
A·S·安德森
J·马库森
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Novo Nordisk AS
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Novo Nordisk AS
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Priority claimed from DK104493A external-priority patent/DK104493D0/da
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Publication of CN1133598A publication Critical patent/CN1133598A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN94193852A 1993-09-17 1994-09-16 酰化的胰岛素和含有这种胰岛素的药物组合物 Expired - Lifetime CN1056618C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK104493A DK104493D0 (da) 1993-09-17 1993-09-17 Hidtil ukendte peptider
DK1044/93 1993-09-17
DK1044/1993 1993-09-17
US19082994A 1994-02-02 1994-02-02
US08/190829 1994-02-02
US08/190,829 1994-02-02

Publications (2)

Publication Number Publication Date
CN1133598A CN1133598A (zh) 1996-10-16
CN1056618C true CN1056618C (zh) 2000-09-20

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ID=26065125

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CN94193852A Expired - Lifetime CN1056618C (zh) 1993-09-17 1994-09-16 酰化的胰岛素和含有这种胰岛素的药物组合物

Country Status (30)

Country Link
US (1) US5750497A (https=)
EP (2) EP1132404A3 (https=)
JP (3) JP3014764B2 (https=)
KR (1) KR100310122B1 (https=)
CN (1) CN1056618C (https=)
AT (1) ATE204882T1 (https=)
AU (2) AU682061B2 (https=)
BG (1) BG61611B1 (https=)
BR (1) BR9407508A (https=)
CA (1) CA2171424C (https=)
CZ (1) CZ287945B6 (https=)
DE (2) DE69428134T2 (https=)
DK (1) DK0792290T3 (https=)
ES (1) ES2163451T3 (https=)
FI (1) FI117055B (https=)
FR (1) FR04C0020I2 (https=)
HU (1) HU217684B (https=)
IL (1) IL110977A (https=)
LU (1) LU91101I2 (https=)
NL (1) NL300160I2 (https=)
NO (3) NO316944B1 (https=)
NZ (1) NZ273285A (https=)
PL (1) PL178466B1 (https=)
PT (1) PT792290E (https=)
RO (1) RO112873B1 (https=)
RU (1) RU2164520C2 (https=)
SI (1) SI0792290T1 (https=)
SK (1) SK282495B6 (https=)
UA (1) UA45321C2 (https=)
WO (1) WO1995007931A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021136296A1 (zh) 2019-12-30 2021-07-08 甘李药业股份有限公司 胰岛素衍生物
WO2021136303A1 (zh) 2019-12-30 2021-07-08 甘李药业股份有限公司 长效glp-1化合物
WO2023143458A1 (zh) 2022-01-28 2023-08-03 甘李药业股份有限公司 酰化胰岛素

Families Citing this family (191)

* Cited by examiner, † Cited by third party
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