CN105636973B - 制备烟酰胺核苷和其衍生物的方法 - Google Patents

制备烟酰胺核苷和其衍生物的方法 Download PDF

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Publication number
CN105636973B
CN105636973B CN201480043268.1A CN201480043268A CN105636973B CN 105636973 B CN105636973 B CN 105636973B CN 201480043268 A CN201480043268 A CN 201480043268A CN 105636973 B CN105636973 B CN 105636973B
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CN105636973A (zh
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M·米高德
P·瑞德帕斯
K·克罗西
M·多尔蒂
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Queens University of Belfast
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201480043268.1A 2013-07-29 2014-07-24 制备烟酰胺核苷和其衍生物的方法 Active CN105636973B (zh)

Priority Applications (1)

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CN201810413840.9A CN108707174A (zh) 2013-07-29 2014-07-24 制备烟酰胺核苷和其衍生物的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1313465.5A GB201313465D0 (en) 2013-07-29 2013-07-29 Methods of preparing nicotinamide riboside and derivatives thereof
GB1313465.5 2013-07-29
PCT/EP2014/065971 WO2015014722A1 (en) 2013-07-29 2014-07-24 Methods of preparing nicotinamide riboside and derivatives thereof

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CN105636973A CN105636973A (zh) 2016-06-01
CN105636973B true CN105636973B (zh) 2018-06-01

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CN201810413840.9A Pending CN108707174A (zh) 2013-07-29 2014-07-24 制备烟酰胺核苷和其衍生物的方法

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US (6) US10000519B2 (enExample)
EP (2) EP3321274A1 (enExample)
JP (1) JP6208352B2 (enExample)
KR (2) KR102303966B1 (enExample)
CN (2) CN105636973B (enExample)
AU (4) AU2014298629B2 (enExample)
BR (1) BR112016001774B1 (enExample)
CA (2) CA3192957A1 (enExample)
ES (1) ES2652654T3 (enExample)
GB (1) GB201313465D0 (enExample)
HK (1) HK1255037A1 (enExample)
MX (1) MX349969B (enExample)
WO (1) WO2015014722A1 (enExample)
ZA (1) ZA201802315B (enExample)

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CN110452277A (zh) * 2018-05-07 2019-11-15 明特奇点医疗科技(成都)有限公司 一种烟酰胺核糖的制备方法
EP3797110A1 (en) * 2018-05-22 2021-03-31 Jumpstart Fertility Pty Ltd Amino acid salts of nicotinic acid ribosides as anti-aging agents
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CN110658224B (zh) * 2019-10-15 2022-11-22 中国中医科学院中药研究所 一种氢核磁定量分析技术测定nmn绝对含量的方法
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BR112016001774A8 (pt) 2020-01-21
AU2022203196A1 (en) 2022-06-02
NZ716277A (en) 2021-03-26
US20240101588A1 (en) 2024-03-28
US20240239831A1 (en) 2024-07-18
CN108707174A (zh) 2018-10-26
KR20160043974A (ko) 2016-04-22
BR112016001774B1 (pt) 2021-06-22
JP6208352B2 (ja) 2017-10-04
CA3192957A1 (en) 2015-02-05
AU2014298629A1 (en) 2016-02-11
ES2652654T3 (es) 2018-02-05
HK1255037A1 (en) 2019-08-02
US11584770B2 (en) 2023-02-21
US11981698B2 (en) 2024-05-14
KR102414886B1 (ko) 2022-07-01
US12252506B2 (en) 2025-03-18
JP2016530248A (ja) 2016-09-29
ZA201802315B (en) 2023-02-22
EP3027635B1 (en) 2017-09-20
US20220259250A1 (en) 2022-08-18
WO2015014722A1 (en) 2015-02-05
HK1218918A1 (en) 2017-03-17
GB201313465D0 (en) 2013-09-11
EP3027635A1 (en) 2016-06-08
CA2918955C (en) 2023-05-09
MX2016001211A (es) 2016-10-28
CN105636973A (zh) 2016-06-01
AU2020201254B2 (en) 2022-05-26
KR102303966B1 (ko) 2021-09-24
US20200291055A1 (en) 2020-09-17
US10000519B2 (en) 2018-06-19
KR20210038718A (ko) 2021-04-07
US20160168184A1 (en) 2016-06-16
AU2018211238A1 (en) 2018-08-16
EP3321274A1 (en) 2018-05-16
AU2022203196B2 (en) 2023-11-23
US10815262B2 (en) 2020-10-27
BR112016001774A2 (pt) 2017-08-01
MX349969B (es) 2017-08-23
CA2918955A1 (en) 2015-02-05
US20180186824A1 (en) 2018-07-05
AU2014298629B2 (en) 2018-08-16
AU2020201254A1 (en) 2020-03-12

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