CN104080916A - 定制供人类使用的抗体、可变结构域和链 - Google Patents
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610883894.2A CN106995822B (zh) | 2011-09-19 | 2012-09-18 | 定制供人类使用的抗体、可变结构域和链 |
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| GB201116122A GB201116122D0 (en) | 2011-09-19 | 2011-09-19 | Synthetically-extended & ethnically diverse superhuman immunoglobulin gene repertoires |
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| CN201280056727.0A Pending CN104080916A (zh) | 2011-09-19 | 2012-09-18 | 定制供人类使用的抗体、可变结构域和链 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107312863A (zh) * | 2017-08-08 | 2017-11-03 | 深圳华大基因研究院 | 利用数字PCR鉴定B淋巴细胞的Ig基因分布的方法 |
| CN107557367A (zh) * | 2017-09-08 | 2018-01-09 | 北京大学人民医院 | Ighg1基因突变体及其应用 |
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| US9445581B2 (en) | 2012-03-28 | 2016-09-20 | Kymab Limited | Animal models and therapeutic molecules |
| PL2517556T3 (pl) | 2009-07-08 | 2016-03-31 | Kymab Ltd | Sposób miejscowo specyficznej rekombinacji, gryzonie i komórki gryzonia zdolne do ekspresji chimerycznych przeciwciał lub łańcuchów |
| EP3960865A1 (en) | 2010-08-02 | 2022-03-02 | Regeneron Pharmaceuticals, Inc. | Mice that make binding proteins comprising vl domains |
| SG2014007686A (en) | 2011-08-05 | 2014-03-28 | Regeneron Pharma | Humanized universal light chain mice |
| JP2014533930A (ja) | 2011-09-19 | 2014-12-18 | カイマブ・リミテッド | 免疫グロブリン遺伝子多様性の操作およびマルチ抗体治療薬 |
| EP2761008A1 (en) | 2011-09-26 | 2014-08-06 | Kymab Limited | Chimaeric surrogate light chains (slc) comprising human vpreb |
| SI3216871T1 (sl) | 2011-10-17 | 2022-04-29 | Regeneron Pharmaceuticals, Inc. | Miš z omejeno težko verigo imunoglobulina |
| US9253965B2 (en) | 2012-03-28 | 2016-02-09 | Kymab Limited | Animal models and therapeutic molecules |
| AU2012323987B2 (en) | 2011-12-20 | 2015-07-09 | Regeneron Pharmaceuticals, Inc. | Humanized light chain mice |
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