CN104039974B - 乙酰辅酶a衍生的类异戊二烯的生产 - Google Patents
乙酰辅酶a衍生的类异戊二烯的生产 Download PDFInfo
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- CN104039974B CN104039974B CN201280066027.XA CN201280066027A CN104039974B CN 104039974 B CN104039974 B CN 104039974B CN 201280066027 A CN201280066027 A CN 201280066027A CN 104039974 B CN104039974 B CN 104039974B
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
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- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01034—Hydroxymethylglutaryl-CoA reductase (NADPH) (1.1.1.34)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/08—Transferases for other substituted phosphate groups (2.7.8)
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- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Biotechnology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161557893P | 2011-11-09 | 2011-11-09 | |
| US61/557,893 | 2011-11-09 | ||
| PCT/US2012/064532 WO2013071172A1 (en) | 2011-11-09 | 2012-11-09 | Production of acetyl-coenzyme a derived isoprenoids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104039974A CN104039974A (zh) | 2014-09-10 |
| CN104039974B true CN104039974B (zh) | 2016-10-12 |
Family
ID=47295179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280066027.XA Active CN104039974B (zh) | 2011-11-09 | 2012-11-09 | 乙酰辅酶a衍生的类异戊二烯的生产 |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US8415136B1 (enExample) |
| EP (1) | EP2776571B1 (enExample) |
| JP (2) | JP6073350B2 (enExample) |
| KR (1) | KR102021914B1 (enExample) |
| CN (1) | CN104039974B (enExample) |
| AU (1) | AU2012335091B2 (enExample) |
| BR (1) | BR112014010750B1 (enExample) |
| CA (1) | CA2853679C (enExample) |
| DK (1) | DK2776571T3 (enExample) |
| ES (1) | ES2628847T3 (enExample) |
| IN (1) | IN2014CN03791A (enExample) |
| MX (1) | MX346459B (enExample) |
| PT (1) | PT2776571T (enExample) |
| SG (1) | SG11201402083XA (enExample) |
| WO (1) | WO2013071172A1 (enExample) |
| ZA (1) | ZA201402989B (enExample) |
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| BR112014002745A8 (pt) * | 2011-08-05 | 2017-06-20 | Danisco Us Inc | produção de isoprenoides sob condições de ph neutro |
| SG11201401249PA (en) | 2011-10-07 | 2014-05-29 | Danisco Us Inc | Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene |
| BR112014010750B1 (pt) * | 2011-11-09 | 2021-09-21 | Amyris, Inc | Produção de isoprenoides derivados de acetil-coenzima a |
| US20150315615A1 (en) * | 2012-12-10 | 2015-11-05 | Cargill, Incorporated | Batch feed process for fermenting sugars |
| EP2971027B1 (en) | 2013-03-15 | 2019-01-30 | Amyris, Inc. | Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds |
| ES2735331T3 (es) * | 2013-04-10 | 2019-12-18 | Goodyear Tire & Rubber | Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides |
| US9617569B2 (en) | 2013-11-15 | 2017-04-11 | Samsung Electronics Co., Ltd. | Genetically engineered yeast cell producing lactate including acetaldehyde dehydrogenase, method of producing yeast cell, and method of producing lactate using the same |
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| EP4296364B1 (en) | 2013-12-03 | 2025-12-03 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
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| JP6470532B2 (ja) * | 2014-09-17 | 2019-02-13 | 積水化学工業株式会社 | 組換え細胞、並びに、有機化合物の生産方法 |
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| BR112014010750B1 (pt) * | 2011-11-09 | 2021-09-21 | Amyris, Inc | Produção de isoprenoides derivados de acetil-coenzima a |
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| CN101023181A (zh) * | 2004-05-21 | 2007-08-22 | 加利福尼亚大学董事会 | 提高类异戊二烯化合物的产生的方法 |
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| AU2012335091B2 (en) | 2016-06-16 |
| BR112014010750A2 (pt) | 2017-06-13 |
| US20140154765A1 (en) | 2014-06-05 |
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| ES2628847T3 (es) | 2017-08-04 |
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| PT2776571T (pt) | 2017-07-07 |
| KR20140093981A (ko) | 2014-07-29 |
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| US20130236942A1 (en) | 2013-09-12 |
| JP6073350B2 (ja) | 2017-02-01 |
| ZA201402989B (en) | 2015-11-25 |
| KR102021914B1 (ko) | 2019-09-17 |
| SG11201402083XA (en) | 2014-06-27 |
| CN104039974A (zh) | 2014-09-10 |
| AU2012335091A1 (en) | 2014-06-19 |
| EP2776571A1 (en) | 2014-09-17 |
| IN2014CN03791A (enExample) | 2015-10-16 |
| US8603800B2 (en) | 2013-12-10 |
| US8859261B2 (en) | 2014-10-14 |
| JP2014532444A (ja) | 2014-12-08 |
| MX346459B (es) | 2017-03-22 |
| US9914941B2 (en) | 2018-03-13 |
| BR112014010750B1 (pt) | 2021-09-21 |
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