CN103651657B - Health-care flour composition and food - Google Patents
Health-care flour composition and food Download PDFInfo
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- CN103651657B CN103651657B CN201310345691.4A CN201310345691A CN103651657B CN 103651657 B CN103651657 B CN 103651657B CN 201310345691 A CN201310345691 A CN 201310345691A CN 103651657 B CN103651657 B CN 103651657B
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- hericium erinaceus
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- weight portion
- food
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Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention provides a health-care flour composition and food and a preparing method thereof. According to the preparing method, hericium erinaceus and flour are used as main raw materials, swelling agents, sweetening agents, oil, salt and the like are added and mixed with water, and then rolling, forming, baking, oil injection and cooling are carried out to obtain various foods made of flour or pastries such as cookies, cakes and noodles. The health-care flour composition and food are even in texture, capable of being stored for a long time easily, good in mouthfeel and rich in nutrient, and market vacancy is filled. The health-care flour composition and food have definite effects in repairing gastric mucosal damage caused by chronic gastritis, or gastric ulcers or duodenal ulcers, relieving abdominal pains caused by chronic gastritis, or gastric ulcers or duodenal ulcers, inhibiting helicobacter pylori, and assisting the treatment of chronic gastritis, gastric ulcers and duodenal ulcers.
Description
Technical field
The present invention relates to a kind of health-care flour composition and food.
Background technology
Along with the raising of people's living standard, the health care consciousness of people is more and more stronger, also more and more higher to the requirement of leisure food.In daily life, pursue food that is delicious, convenient, that be of high nutritive value and become fashion.In numerous leisure food, that likes for most people surely belongs to wheaten food or millet cake: as biscuit, bread, cake or instant noodles etc.This based food can not only supplement body energy, and each tool local flavor, all-ages.But, this series products of the prior art, though mouthfeel pretty good, there is full abdomen function, but nutritive value is limited.At present, rarely seenly on market can play the food with health care improving immunity of organisms, prevention or adjuvant treatment of diseases, therefore, be difficult to the requirement meeting modern.
Hericium erinaceus is a kind of high protein, low fat, be rich in the excellent food of minerals and vitamins, containing unrighted acid, can reduce cholesterolemia and content of triglyceride, adjusting blood lipid, be beneficial to blood circulation.The polysaccharide body that Hericium erinaceus contains, polypeptide class and fatty material, the disease of digestive tracts such as energy prevention and therapy gastric ulcer, duodenal ulcer, have the function improving immunity of organisms, and delaying sanility.But Hericium erinaceus eats usually used as the vegetables of rare kind in daily life, and eating method is complicated, and inconvenience often eats, and amount is not enough, and health-care effect is difficult to give full play to.
Hericium erinaceus (Hericium erinaceum) is widely used for disease such as treatment chronic gastritis, gastroduodenal ulcer etc. on clinical medicine, have accumulated a large amount of clinical experiences and data.But yet there are no the daily edible food with health care that application Hericium erinaceus is made on the market.
Chinese Patent Application No. 200510046418.7 discloses a kind of nutrition wheat flour containing fruit or vegetables and method for making, is the fruit of vacuum freeze drying or vegetables to be made dry powder and wheat flour is mixed.Shortcoming is that the fruit of pulverizing or vegetables have certain granules degree, is difficult to mix completely with wheat flour, affects the ferment effect of dough, and the outward appearance of product and mouthfeel existing defects.Chinese Patent Application No. 99113217.3 discloses a kind of production method of pesticide-eating fungus floor, is with wheat or mung bean for culture medium, and inoculated fungi bacterial classification, dries and pulverize to obtain domestic fungus flour.Shortcoming is flour preparation and processing conditions harshness, and flour should not be preserved, and preparation Flour product kind is limited.
Summary of the invention
The object of this invention is to provide a kind of apply to suitability for industrialized production, homogeneous, be easy to long-term preservation, be suitable for preparing polytype wheaten food or millet cake, comfortable taste, nutritious health-care flour composition and food, to solve the deficiencies in the prior art, make up the market vacancy.
The invention provides a kind of health-care flour composition, it is characterized in that Hericium erinaceus to add in flour, by the deep processing to flour, obtain a kind of health-care flour composition.Specifically, health-care flour composition of the present invention contains flour 100 weight portion, Hericium erinaceus 1 ~ 30 weight portion, wherein Hericium erinaceus can be not only new fresh Hericium erinaceus or dry product Hericium erinaceus or Hericium erinaceus powder (commercially available buy), also can be Hericium erinaceus fresh goods or dry product raw material adds water and/or alcohol extracting obtains extract or extract is dry and Hericium erinaceus extract that is that obtain; Also can be and Hericium erinaceus fresh goods or dry product raw material are added water and/or alcohol extracting, and material after extracting is carried out Hericium erinaceus extract inclusion compound that inclusion obtains or microcapsules.Preferred Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07.Preferred Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, dry and obtain.Preferred Hericium erinaceus extract inclusion compound or microcapsules are that Hericium erinaceus fresh goods or dry product raw material add water and/or be concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, by water-soluble for one or more in concentrate and cyclodextrin, gelatin, converted starch, natural plant gum, alginic acid, add thermal agitation, be cooled to room temperature, dry and obtain.
Especially, the invention provides a kind of health-care flour composition for the preparation of wheaten food or cake being easy to digest and assimilate, this health-care flour composition contains: flour 100 weight portion, Hericium erinaceus 1 ~ 30 weight portion, leavening agent 0.1 ~ 2.5 weight portion.Wherein Hericium erinaceus can be not only new fresh Hericium erinaceus or dry product Hericium erinaceus or Hericium erinaceus powder, also can be Hericium erinaceus extract or the dry and Hericium erinaceus extract that obtains of extract or Hericium erinaceus extract inclusion compound or microcapsules.Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07.Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, dry and obtain.Hericium erinaceus extract inclusion compound or microcapsules are that Hericium erinaceus fresh goods or dry product raw material add water and/or be concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, by water-soluble for one or more in concentrate and cyclodextrin, gelatin, converted starch, natural plant gum, alginic acid, add thermal agitation, be cooled to room temperature, dry and obtain.The appropriate sweetener of food can also be added in health-care flour composition of the present invention, preferably add sweetener 1 ~ 35 weight portion.
In a preferred embodiment of the invention, health-care flour composition of the present invention contains: flour 100 weight portion, Hericium erinaceus 5 ~ 20 weight portion, leavening agent 0.1 ~ 2.0 weight portion, sweetener 10 ~ 30 weight portion.In an especially preferred embodiment, health-care flour composition composition of the present invention is: flour 100 weight portion, Hericium erinaceus 5 ~ 20 weight portion, leavening agent 0.1 ~ 2.0 weight portion, sweetener 10 ~ 30 weight portion.In the inventive solutions, Hericium erinaceus can be not only new fresh Hericium erinaceus or dry product Hericium erinaceus or Hericium erinaceus powder, also can be and Hericium erinaceus fresh goods or dry product raw material added water and/or is concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, the Hericium erinaceus extract of preferred specific gravity 1.04 ~ 1.07; Or Hericium erinaceus fresh goods or dry product raw material added water and/or is concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, dry and obtain; Also can be and fresh goods or dry product Hericium erinaceus raw material are added water and/or concentrates after alcohol extracting, and it is water-soluble with one or more in cyclodextrin, gelatin, converted starch, natural plant gum, alginic acid, add thermal agitation, be cooled to room temperature, drying, carries out Hericium erinaceus extract inclusion compound that inclusion obtains or microcapsules.More preferably, health-care flour composition provided by the invention contains: flour 100 weight portion, Hericium erinaceus 5 ~ 20 weight portion, leavening agent 0.5 ~ 1.5 weight portion, sweetener 5 ~ 20 weight portion, wherein Hericium erinaceus can be not only new fresh Hericium erinaceus or dry product Hericium erinaceus or Hericium erinaceus powder, also can be Hericium erinaceus extract or the dry and Hericium erinaceus extract that obtains of extract or Hericium erinaceus extract inclusion compound or microcapsules.Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07; Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, dry and obtain; Hericium erinaceus extract inclusion compound or microcapsules are that Hericium erinaceus fresh goods or dry product raw material add water and/or alcohol extracting, extract is concentrated into proportion 1.02 ~ 1.10, by water-soluble for one or more in concentrate and cyclodextrin, gelatin, converted starch, natural plant gum, alginic acid, add thermal agitation, be cooled to room temperature, dry and obtain.In one embodiment of the invention, health-care flour composition provided by the invention contains: flour 100 weight portion, Hericium erinaceus 3 ~ 7 weight portion, leavening agent 0.5 ~ 1.5 weight portion, sweetener 15 ~ 30 weight portion, wherein Hericium erinaceus can be not only new fresh Hericium erinaceus or dry product Hericium erinaceus or Hericium erinaceus powder, also can be Hericium erinaceus extract or the dry and Hericium erinaceus extract that obtains of extract or Hericium erinaceus extract inclusion compound or microcapsules.Preferably, above-mentioned Hericium erinaceus extract is that Hericium erinaceus fresh goods or dry product raw material add water and/or are concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07; Above-mentioned Hericium erinaceus extract is that Hericium erinaceus raw material adds water and/or is concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, dry and obtain; Above-mentioned Hericium erinaceus extract inclusion compound or microcapsules are that Hericium erinaceus fresh goods or dry product raw material add water and/or be concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, preferred specific gravity 1.04 ~ 1.07, by water-soluble for one or more in concentrate and cyclodextrin, gelatin, converted starch, natural plant gum, alginic acid, add thermal agitation, be cooled to room temperature, dry and obtain.
In an embodiment be more preferably, by new fresh Hericium erinaceus, cleaning, dry, pulverize 40-80 mesh sieve with pulverizer, obtain crude product; Again through ultracentrifugation beveller, under 12000r/min-16000r/min condition, pulverize 10-20 min, obtain 350-500 order Ultramicro-powder.Preferably, Hericium erinaceus raw material is pulverized, adds weight ratio 10 ~ 20 times of soak by water 1 ~ 3 time, each 1 ~ 2 hour, merge decoction liquor, after filtration, be concentrated into proportion 1.02 ~ 1.10, preferably, proportion 1.04 ~ 1.07, dry Hericium erinaceus extract.Or, Hericium erinaceus raw material is pulverized, adds weight ratio 3 ~ 8 times of alcohol dipping 15 ~ 35 days; Or alcohol reflux extracts 1 ~ 3 time, each 2 ~ 4 hours, maceration extract or extract reclaim ethanol, are concentrated into proportion 1.02 ~ 1.10, preferably, and proportion 1.04 ~ 1.07, dry Hericium erinaceus extract.Or, Hericium erinaceus raw material is pulverized, adds weight ratio 3 ~ 8 times of alcohol dipping 15 ~ 35 days, or refluxing extraction 1 ~ 3 time, each 1 ~ 3 hour, after maceration extract or extract reclaim ethanol, for subsequent use; Hericium erinaceus after alcohol extracting adds weight ratio 15 ~ 20 times of soak by water 1 ~ 3 time, each 1 ~ 2 hour, and decoction liquor then to merge with alcohol extract after filtering, and is concentrated into proportion 1.02 ~ 1.10, preferably, proportion 1.04 ~ 1.07, dry must Hericium erinaceus extract.Also ethanol can be replaced to extract with propyl alcohol and/or butanols, or use ethanol and/or propyl alcohol and/or butanols.
The inclusion agents that in health-care flour composition material of the present invention, Hericium erinaceus extract inclusion compound uses is cyclodextrin, and wherein, cyclodextrin is selected from alpha-cyclodextrin, beta-schardinger dextrin-, gamma-cyclodextrin or their derivative, such as HP-β-CD.Preferred use beta-schardinger dextrin-.The method preparing cyclodextrin inclusion compound includes but not limited to saturated water solution method, ultrasonic method, freeze-drying or spray drying process.The capsule material that in health-care flour composition material of the present invention, Hericium erinaceus extract microcapsules uses is selected from one or more in converted starch, gelatin, natural plant gum, alginic acid.The method preparing microcapsules includes but not limited to spray drying process, extrusion, misting cooling/condensation method or point attached bag connection.In one embodiment of the invention, by Hericium erinaceus extract concentrate and cyclodextrin water-soluble, add thermal agitation, be cooled to room temperature, spraying dry, obtain Hericium erinaceus extract cyclodextrin inclusion compound.More preferably, by Hericium erinaceus extract concentrate and cyclodextrin water-soluble according to weight ratio 1:1 ~ 20, the weight ratio of cyclodextrin and water is 1:1 ~ 20.Heating inclusion temperature is 30 ~ 45 DEG C, and mixing time is more than 15 minutes.In another embodiment of the invention, Hericium erinaceus extract microcapsules takes extract, adds suitable quantity of water, and heating for dissolving makes core material solution.Take a certain amount of gelatin, add a certain amount of water, make its swelling, dispersion, 40 DEG C of heating water baths make it dissolve, and make wall material solution.According to certain wall material core ratio (5:1 ~ 15:1, m/m) and certain wall material concentration level (1:50, m/V) requirement, core material solution is joined in wall material solution, stir, mixing, spraying dry and get final product.More preferably, be that wall material core is than 10:1 (m/m), EAT 170 DEG C, feed rate 3mL/min by the comparatively suitable drying process with atomizing condition of orthogonal design optimization.With this understanding, the microcapsules that average grain diameter is 11.93 μm have been prepared.
Flour described in health-care flour raw material of the present invention is selected from but is not limited to one or more powder made for raw material grinding mill in wheat, rice, corn, millet, barley, jowar, the seed of Job's tears, glutinous rice, oat, buckwheat, naked oats, pumpkin, the root of kudzu vine, potato, cassava, soya bean, red bean, mung bean, kidney bean, broad bean, pea, cowpea, chick-pea, lotus root, water caltrop, lily, konjaku, banana dasheen.Preferably, described in health-care flour raw material of the present invention, flour is that wheat flour adds coarse cereal powder, and more preferably, described in health-care flour raw material of the present invention, flour is wheat flour.
In one embodiment of the invention, food auxiliary material can also be added in health-care flour composition of the present invention, such as 101-130 weight portion flour composition, can add food appropriate, one or more in the vitamin, starch, salt, five-spice powder etc. of preferred 0.2 ~ 10 weight portion.In another embodiment of the invention, food additives can also be added in health-care flour composition of the present invention, such as 101-130 weight portion flour composition, one or more in the monosodium glutamate of 0.02 ~ 5 weight portion, milk powder, essence, stearoyl lactate, disodium ethylene diamine tetraacetate etc. can be added.Described essence includes but not limited to one or more in vanillic aldehyde, the turbid essence of milk etc.
Leavening agent of the present invention is selected from but is not limited to one or more in sodium bicarbonate, baking powder, ammonia bicarbonate (carbonic hydroammonium), alum, sodium pyrosulfite, Sodium Acid Pyrophosphate, yeast.Preferably, leavening agent of the present invention is one or more in sodium bicarbonate, ammonia bicarbonate, sodium pyrosulfite, Sodium Acid Pyrophosphate.Preferred, leavening agent of the present invention is sodium bicarbonate.
Sweetener in health-care flour composition raw materials of the present invention is selected from one or more in glucose, fructose, sucrose, maltose, starch sugar, lactose, stevioside, Aspartame, 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one 2,2-dioxide potassium salt, saccharin sodium, honey element, maltitol.
Health-care flour composition of the present invention is made by processing method below: to weigh each composition by proportioning, be uniformly mixed; Or to weigh each composition by proportioning, ground and mixed; Or to weigh each composition by proportioning, mixing of sieving; Or each composition of weighing by proportioning is placed in container rotating type mixer mix; Or each composition of weighing by proportioning is placed in container fixed mixer mix; Or the flour of weighing by proportioning is placed in fluid bed granulator, the mixture aqueous solution of the Hericium erinaceus of weighing by proportioning and other composition is mixed by drying.
On the other hand, the invention provides the dough prepared with health-care flour composition of the present invention, described health-care flour composition is made dough, leave standstill.If needed, allow dough fermentation.Health-care flour composition fatten of the present invention, flavoring essence and water, can make shortbread type biscuit or soda cracker.Described grease, include but not limited in butter, butter, lard, shortening, edible vegetable oil these one or more.One or more in the preferred coconut oil of described edible vegetable oil, palm oil, olive oil, salad oil, peanut oil, tea-seed oil, soya-bean oil, sesame oil, long beggar's oil.Preferably, 10 ~ 30 weight portion greases are added in 101-130 weight portion dough.In dough of the present invention, one or more pastry product industry that can also add in egg, vegetables, shredded coconut meat, dry fruit, raisins, chocolate, cocoa power, dried meat floss etc. commonly use auxiliary material.
The appropriate food additives of food can be added in dough of the present invention, include but not limited to one or more in acidity regulator, anticaking agent, defoamer, antioxidant, colouring agent, color stabilizer, enzyme preparation, flavoring agent, nutrition fortifier, anticorrisive agent, sweetener, thickener, spices.
Again on the one hand, the invention provides the food with health care prepared with health-care flour composition of the present invention or dough, include but not limited to biscuit, bread, instant noodles, steamed bun, noodles or cake etc.Health-care flour composition of the present invention is made dough, if needed, ferments, pressing mold base, baking, if needed, low temperature drying, obtains health care flour-made food.
Preferably, biscuit dough in preparation technology prepared by health-care flour composition of the present invention or dough is baked by 3 ~ 4 stoving temperature districts successively, and stoving temperature 150 ~ 360 DEG C, always cures 4 ~ 8 minutes time.Biscuit prepared by health-care flour composition of the present invention or dough can be coated with chocolate cream, jam or other tartar sauce and make sandwich biscuits or decoration biscuit between biscuit monolithic.
In a preferred technical scheme of the present invention, the step preparing shortbread type biscuit comprises:
(1) modulate dough: take each raw material by described composition of raw materials: first sweetener and grease are mixed to get material A; By leavening agent, salt, flavoring essence mixing, and the material B that is dissolved in water to obtain; Material A, material B, Hericium erinaceus, other raw material and water are dropped in mixer successively, is stirred to evenly; Then by flour and the mixing of above-mentioned homogeneous material, add water and continue to be stirred to evenly, for subsequent use;
(2) compressing: the biscuit green compact being made various shape through roll marks shaping mechanism;
(3) cure: biscuit green compact are sent into curer baking, burner hearth is divided into four districts: 1 setting face, district temperature 220 ~ 235 DEG C, end temperature 200 ~ 220 DEG C; 2 setting face, district temperature 230 ~ 250 DEG C, end temperature 190 ~ 210 DEG C; 3 setting face, district temperature 230 ~ 240 DEG C, end temperature 200 ~ 210 DEG C; 4 setting face, district temperature 160 ~ 200 DEG C, end temperature 170 ~ 210 DEG C; Wholely cure 4 ~ 10 minutes time;
(4) oil spout: biscuit is come out of the stove rear surface oil spout;
(5) pack: by the biscuit after oil spout through arranging, packaging, finished product.
In a preferred technical scheme of the present invention, the step preparing soda cracker comprises:
(1) dough preparing and fermentation: first part flour, Hericium erinaceus are dropped into and adjust in powder cylinder, slowly add the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into after adjusting powder machine to start, be blended into dough; Then pour in fermentation tank by dough, controlling dough temperature is 28 ~ 32 DEG C, ferments 6 ~ 10 hours; Complete dough preparing and fermentation for the first time; Again dropped into by the dough that first time has fermented and adjust in powder cylinder, add all the other flour and the Hericium erinaceus of formula regulation, then add grease, sweetener, salt, flavoring essence and other raw material and water, start and adjust powder machine, mixed, second time dough preparing completes; Poured into by dough in fermentation tank, controlling dough temperature is 30 ~ 35 DEG C, ferments 4 ~ 6 hours;
Dough sheet calendering and shaping: through stamped or rolling cut dough sheet, cut out the biscuit green compact of different appearance profile;
(3) cure: biscuit green compact are sent into curer baking, burner hearth is divided into three districts: 1 setting face, district temperature 190 ~ 210 DEG C, end temperature 320 ~ 360 DEG C; 2 setting face, district temperature 240 ~ 280 DEG C, end temperature 230 ~ 250 DEG C; 3 setting face, district temperature 180 ~ 220 DEG C, end temperature 180 ~ 220 DEG C.Wholely cure 5 ~ 8 minutes time;
(4) oil spout: biscuit is come out of the stove rear surface oil spout;
(5) pack: by the biscuit after oil spout through arranging, packaging, finished product.
In another preferred technical scheme of the present invention, the step preparing soda cracker comprises:
(1) dough preparing and fermentation: first flour, Hericium erinaceus are dropped into and adjust in powder cylinder, add grease, sweetener, salt, sodium bicarbonate, flavoring essence and other raw material again, after adjusting powder machine to start, slowly add the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, be blended into dough; Then pour in fermentation tank by dough, controlling dough temperature is 33 ~ 34 DEG C, ferments 4 hours; Complete dough preparing and fermentation;
Dough sheet calendering and shaping: through stamped or rolling cut dough sheet, cut out the biscuit green compact of different appearance profile;
(3) cure: biscuit green compact are sent into curer baking, burner hearth is divided into three districts: 1 setting face, district temperature 190 ~ 210 DEG C, end temperature 320 ~ 360 DEG C; 2 setting face, district temperature 240 ~ 280 DEG C, end temperature 230 ~ 250 DEG C; 3 setting face, district temperature 180 ~ 220 DEG C, end temperature 180 ~ 220 DEG C; Wholely cure 7 ~ 10 minutes time;
(4) oil spout: biscuit is come out of the stove rear surface oil spout;
(5) pack: by the biscuit after oil spout through arranging, packaging, finished product.
In a preferred embodiment of the invention, the raw material of biscuit prepared of health-care flour composition of the present invention is containing, for example lower weight proportion:
Wheat flour 100 parts
Hericium erinaceus 1 ~ 30 part
Leavening agent 0.1 ~ 2.5 part
Sweetener 1 ~ 35 part
Grease 10 ~ 30 parts
Salt 0.6 ~ 2 part
Flavoring essence 0.02 ~ 5 part
10 ~ 30 parts, water.
The raw material of above-mentioned biscuit prepared by health-care flour composition of the present invention can also contain further:
Starch 0.2 ~ 10 part
Milk powder 0.02 ~ 5 part
The food of the Hericium erinaceus extract that the present inventor finder eats containing 8 ~ 15 grams of Hericium erinaceus crude drug amounts day can reach daily health caring effect.Therefore, on the one hand, the invention provides the purposes of health-care flour composition of the present invention in preparation has the food repairing the gastric mucosa injure function that chronic gastritis, gastric ulcer or duodenal ulcer cause.Another aspect, present invention also offers health-care flour composition of the present invention and is preparing the purposes had in the food of the abdominal pain function that relieve chronic gastritis, gastric ulcer or duodenal ulcer cause.On the other hand, present invention also offers health-care flour composition of the present invention and prepare the purposes had in the food of supplemental treatment chronic gastritis, gastric ulcer, duodenal ulcer function.Again on the one hand, present invention also offers the purposes of health-care flour composition of the present invention in preparation has the food suppressing helicobacter pylori function.
Modern often because work, rhythm of life are fast, has no time to have meal on time; Or eat and drink immoderately because of excessive hunger after missing meal time, thus cause stomach and intestine indigestion, gasteremphraxis, feel sick, the digestion such as stomachache class problem occurs again and again, health is usually in sub-health state.But most people is often taken exception to this type of healthy hidden danger, think that these symptoms just cause owing to not taking food, thus often ignore the health care to stomach and intestine in daily life.Except the stomach trouble crowd that doctor makes a definite diagnosis, general upset,gastro-intestinal crowd initiatively can not take the medicine for the treatment of stomach trouble.
The raw material Hericium erinaceus of health-care flour composition of the present invention is recorded according to Compendium of Material Medica: property is put down, and taste is sweet, has the function of " sharp the five internal organs, aid digestion ".Modern study also shows that Hericium erinaceus has invigorating spleen and reinforcing stomach, norcholesterol, nourishing, anticancer, the effect such as to protect the liver.The leisure food such as biscuit, bread, instant noodles, steamed bun, noodles or cake that health-care flour composition of the present invention is prepared into, solve people in daily life to eat Hericium erinaceus and need cook not only consuming time but also be limited to the inconvenience in place, make this Precious Edible Fungi having nutritive value and health-care efficacy of Hericium erinaceus from the bamboo mat spread on the floor for people to sit in ancient China dinner of luxury, enter in common people's daily life.Food prepared by health-care flour composition of the present invention was both convenient for carrying, and was easy to again storage.For the crowd that cannot have meal that is busy with one's work on time, this based food can be their makeup energy in time.In addition, because this based food has the gastric mucosa injure function of repairing chronic gastritis, gastric ulcer or duodenal ulcer and causing; There is the abdominal pain function that relieve chronic gastritis, gastric ulcer or duodenal ulcer cause; Also can suppress helicobacter pylori, supplemental treatment chronic gastritis, gastric ulcer, duodenal ulcer, people eat this based food, and can play a role in health care again while alleviation hunger, be kill two birds with one stone.
The Hericium erinaceus of adding in health-care flour composition of the present invention, except can being new fresh Hericium erinaceus or dry product Hericium erinaceus or Hericium erinaceus powder, also Hericium erinaceus fresh goods or dry product raw material are added water and/or concentrated gained Hericium erinaceus extract or the dry and Hericium erinaceus extract that obtains of extract after alcohol extracting; Also fresh goods or dry product Hericium erinaceus raw material are added water and/or alcohol extracting, and material after extracting is carried out Hericium erinaceus extract inclusion compound that inclusion obtains or microcapsules.Hericium erinaceus food of the prior art, adds after Hericium erinaceus fresh goods or dry product first need being decocted making beating again or Hericium erinaceus Strains is obtained zymotic fluid add through fermentation during preparation.Health-care flour composition of the present invention by comparison, directly as raw-food material, not only can fully remain the abundant nutrition composition in Hericium erinaceus raw material, and is easier to obtain, and is conducive to storing and deep processing, adapts to industrialized production.Health-care flour composition of the present invention is in the Hericium erinaceus extract situation containing higher deal, its mouthfeel has a little bitterness, consider that consumer often extremely focuses on the mouthfeel of food, the present invention does not adopt the mode adding the flavourings such as sugar to cover pained taste, but explored by repetition test, determine the inclusion technique parameter of Hericium erinaceus extract, solved the problem of its mouthfeel shortcoming by inclusion.While ensure that food mouthfeel, also decrease adding of sweetener, for diabetes patient or other crowd that need control sugared part intake provide the possibility of this based food edible as much as possible.In addition, because Hericium erinaceus extract draws moist comparatively strong, make the health-care flour composition prepared for raw material with it in storage process, the easy moisture absorption goes bad, thus affects the stability of product.Adopt inclusion technique can prevent the Hericium erinaceus extract moisture absorption, thus improve the stability of made health-care flour composition.In addition, inventor also finds that the Hericium erinaceus extract inclusion compound that the process of employing inclusion technique obtains or microcapsules obviously can increase the solubility of the effective health-care components of Hericium erinaceus extract, improves its bioavilability, improves its stability simultaneously, reduce excitant.
Amount containing Hericium erinaceus in health-care flour composition of the present invention is determined through repetition test, not only has no adverse effect to the mouthfeel of the food made with this health-care flour composition, and at the gastric mucosa injure that reparation chronic gastritis, gastric ulcer or duodenal ulcer cause; The abdominal pain that relieve chronic gastritis, gastric ulcer or duodenal ulcer cause; Suppress helicobacter pylori, there is precise effects supplemental treatment chronic gastritis, gastric ulcer, duodenal ulcer aspect.We have carried out effect contrast to the biscuit prepared with health-care flour composition of the present invention and commercially available common digestion class biscuit, and concrete test is as follows:
1, clinical data
Select to confirm to suffer from disease of stomach patient 50 example, 18 ~ 55 years old age, male or female through gastrocopy.Selected within first 1 week, once took PPI or bisfentidine person forecloses.Patient is divided at random observation group and each 25 examples of control group, superficial gastritis 10 example in treatment group, erosive gastritis 5 example, atrophic gastritis 5 example, gastric ulcer 3 example, duodenal ulcer 2 example; Superficial gastritis 9 example in control group, erosive gastritis 7 example, atrophic gastritis 5 example, gastric ulcer 2 example, duodenal ulcer 2 example.Two groups of ordinary circumstances have comparativity.
2, Dietotherapy method
By the biscuit (every day takes biscuit amount 60g, wherein containing 10g Hericium erinaceus crude drug) that embodiment 28 method is made in observation group's edible " detailed description of the invention ", edible 4 weeks.Control group eats commercially available digestive biscuit, and edible time and amount are all identical with observation group.
3, curative effect determinate standard
Effective: symptom disappears substantially, gastrocopy still has mild inflammation to change; Effective: symptom is improved, gastrocopy gastritis scope reduces to some extent, alleviates; Invalid: symptom is not improved, gastrocopy gastritis situation is not improved.
4, result
As seen from the experiment, the Hericium erinaceus biscuit that health-care flour composition of the present invention is made has the gastric mucosa injure repaired chronic gastritis, gastric ulcer or duodenal ulcer and cause, relieve chronic gastritis, gastric ulcer cause abdominal pain, suppress helicobacter pylori, the effect of supplemental treatment chronic gastritis, gastric ulcer or duodenal ulcer disease.
Health-care flour composition of the present invention has carried out deep processing to long patent flour, and effect has had this qualitative leap compared with long patent flour.And the present inventor finds, when adding 1 ~ 30 weight portion Hericium erinaceus in 100 weight portion flour, obtained food mouthfeel is good.Concrete test is as follows:
1, experiment purpose: the quality of the 5 kinds of shortbread type biscuit finished products adopting different ratios of raw materials to make is evaluated.
2, laboratory sample:
The raw material of 2.1 samples 1 and preparation method:
Raw material: 4 kilograms, flour, Hericium erinaceus 0.2 kilogram, leavening agent 47 grams, grease 0.7 kilogram, sweetener 0.5kg, in right amount other auxiliary material.
Preparation method:
1) dough is modulated: take each raw material by described composition of raw materials: first sweetener and grease are mixed to get material 1; By leavening agent, salt, flavoring essence mixing, and the material 2 that is dissolved in water to obtain; Material 1, material 2, Hericium erinaceus extract and water are dropped in mixer successively, is stirred to evenly; Then by flour and the mixing of above-mentioned homogeneous material, add water and continue to be stirred to evenly, for subsequent use.
2) compressing: the biscuit green compact being made various shape through roll marks shaping mechanism;
3) cure: biscuit green compact are sent into curer baking, burner hearth is divided into four districts: 1 setting face, district temperature 235 DEG C, end temperature 210 DEG C; 2 setting face, district temperature 230 DEG C, end temperature 200 DEG C; 3 setting face, district temperature 230 DEG C, end temperature 200 DEG C; 4 setting face, district temperature 190 DEG C, end temperature 200 DEG C.Wholely cure 4 minutes time.
4) oil spout: biscuit is come out of the stove rear surface oil spout.
5) pack: by the biscuit after oil spout through arranging, packaging, finished product.
The raw material of 2.2 samples 2 and preparation method:
Raw material: 4 kilograms, flour, Hericium erinaceus 0.6 kilogram, leavening agent 52 grams, grease 0.8 kilogram, sweetener 0.6 kilogram, in right amount other auxiliary material.
Preparation method is with sample 1.
The raw material of 2.3 samples 3 and preparation method:
Raw material: 4 kilograms, flour, Hericium erinaceus 1.2 kilograms, leavening agent 58 grams, grease 0.9 kilogram, sweetener 0.7 kilogram, in right amount other auxiliary material.
Preparation method is with sample 1.
The raw material of 2.4 samples 4 and preparation method:
Raw material: 4 kilograms, flour, Hericium erinaceus 2 kilograms, leavening agent 68 grams, grease 1 kilogram, sweetener 0.8 kilogram, in right amount other auxiliary material.
Preparation method is with sample 1.
The raw material of 2.5 samples 5 and preparation method:
Raw material: 4 kilograms, flour, Hericium erinaceus 2.8 kilograms, leavening agent 0.12 kilogram, grease 1.3 kilograms, sweetener 1.4 kilograms, in right amount other auxiliary material.
Preparation method is with sample 1.
3, experimental procedure:
After biscuit completes and cools, select experienced personnel 50 (25 male sex and 25 women, 20 ~ 50 years old age), mark by shortbread type biscuit organoleptic indicator standards of grading (see table 1), finally average, total score is 100 points, the results are shown in Table 2.
Above experimental result shows, when adding 1 ~ 30 weight portion Hericium erinaceus in 100 weight portion flour, obtained food mouthfeel is good.
Detailed description of the invention
the preparation of embodiment 1 Hericium erinaceus water extract of the present invention
Take 10 kilograms of Hericium erinaceus dried food and nuts, pulverize, add 100 premium on currency, decoct 2 hours, filter, collect filtrate.In residue, add 80 premium on currency again, decoct 2 hours, filter, collect filtrate, twice gained filtrate merged, being concentrated into proportion is 1.06, and spraying dry obtains Hericium erinaceus extract 3 kilograms.
the preparation of embodiment 2 Hericium erinaceus alcohol extract of the present invention
Take 15 kilograms of Hericium erinaceus dried food and nuts, pulverize, add 125 liter of 50% ethanol, flood 20 days, after maceration extract reclaims distillation ethanol, be concentrated into proportion 1.06, spraying dry obtains Hericium erinaceus extract 1.5 kilograms.
the preparation of embodiment 3 Hericium erinaceus alcohol extract of the present invention
Take 18 kilograms of Hericium erinaceus dried food and nuts, pulverize, add 250 liter of 60% ethanol, to keep being heated under fluidized state refluxing extraction 2 hours, filter, extract reclaims ethanol, and be concentrated into proportion 1.05, spraying dry obtains Hericium erinaceus extract 1.3 kilograms.
the preparation that embodiment 4 Hericium erinaceus Ultramicro-powder of the present invention minces
Take 20 kilograms of new fresh Hericium erinaceus, cleaning, dry, pulverize 60 mesh sieves with pulverizer, obtain crude product; Again through ultracentrifugation beveller, under 16000r/min condition, pulverize 15 min, obtain 350-500 order Ultramicro-powder.
the preparation of embodiment 5 Hericium erinaceus alcohol and water of the present invention extract
Take 20 kilograms of Hericium erinaceus dried food and nuts, pulverize, add 188 liter of 70% ethanol, to keep being heated under fluidized state refluxing extraction 2 times, each 1.5 hours, after extract reclaims ethanol, for subsequent use.Hericium erinaceus after alcohol extracting is added 115 premium on currency, decocts 2 times, each 2 hours, decoction liquor is filtered afterwards and reflux extracting liquid merges, and being concentrated into proportion is 1.08, and spraying dry obtains Hericium erinaceus extract 6 liters.
the preparation of embodiment 6 Hericium erinaceus extract microcapsules of the present invention
By the Hericium erinaceus extract that 8 kilograms obtain by embodiment 1 method, add 1L water, heating for dissolving makes core material solution.Take 16 kilograms of gelatin, add 800 premium on currency, at 40 DEG C, heating water bath makes it dissolve, and makes wall material solution.Core material solution joined in wall material solution, stir, mixing, spraying dry, obtains Hericium erinaceus extract microcapsules.
the preparation of embodiment 7 Hericium erinaceus alcohol extract of the present invention inclusion compound
The Hericium erinaceus extract that 5 kilograms obtain by embodiment 3 method is joined in 375 aqueous solution of 75 kilograms of HP-β-CDs, with sonicator process 20 minutes, by the sedimentation and filtration of separating out, washing, dry, obtain Hericium erinaceus extract inclusion compound.
the preparation of embodiment 8 Hericium erinaceus extract of the present invention inclusion compound
The Hericium erinaceus extract obtained 6 kilograms by embodiment 5 method and 120 kg beta-schardinger dextrin-are dissolved in 1800 premium on currency, stir 20 minutes at 38 DEG C, and cooling, spraying dry, obtains Hericium erinaceus extract inclusion compound.
the preparation of embodiment 9 Hericium erinaceus extract microcapsules of the present invention
By the Hericium erinaceus extract that 5 kilograms obtain by embodiment 5 method, add 15 premium on currency, heating for dissolving makes core material solution.Take 10 kilograms of gelatin and add 500 premium on currency, at 38 DEG C, heating water bath makes it dissolve, and makes wall material solution.Core material solution joined in wall material solution, stir, mixing, spraying dry, obtains Hericium erinaceus extract microcapsules.
the preparation of embodiment 10 health-care flour composition of the present invention
Take 10 kilograms of wheat flours, 1.2 kilograms of Hericium erinaceus extracts obtained by embodiment 1 method, are uniformly mixed, and obtain health-care flour composition of the present invention.
the preparation of embodiment 11 health-care flour composition of the present invention
By Hericium erinaceus extract 0.3 liter of water that 2.3 kilograms obtain by embodiment 2 method; Take 15 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 12 health-care flour composition of the present invention
Take 12 kilograms of wheat flours, 2.9 kilograms of Hericium erinaceus extracts obtained by embodiment 3 method, 0.3 kilogram of sodium bicarbonate, ground and mixed is even, obtains health-care flour composition.
the preparation of embodiment 13 health-care flour composition of the present invention
By 1.8 kilograms of Hericium erinaceus extracts obtained by embodiment 4 method, 0.2 kilogram of sodium bicarbonate, 1.5 kilograms of white sugar 0.3 liter of water; Take 10 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 14 health-care flour composition of the present invention
By 1.8 kilograms of Hericium erinaceus extracts obtained by embodiment 5 method, 0.15 kilogram of sodium bicarbonate, 1.2 kilograms of stevioside 0.25 liter of water; Take 9 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 15 health-care flour composition of the present invention
By 0.3 kilogram of Hericium erinaceus extract obtained by embodiment 5 method, 0.2 kilogram of sodium bicarbonate, 0.6 kilogram of white sugar 0.1 liter of water; Take 16 kilograms of wheat flours, 0.3 kilogram of glutinous rice flour is placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 16 health-care flour composition of the present invention
By 1.3 kilograms of Hericium erinaceus extracts obtained by embodiment 3 method, 0.35 kilogram of sodium bicarbonate 0.3 liter of water; Take 18 kilograms of wheat flours, 3 kilograms of glutinous rice, 2 kilograms of buckwheats are placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 17 health-care flour composition of the present invention
By Hericium erinaceus extract 0.2 liter of water that 1 kilogram obtains by EXAMPLE Example 1 method; Take 10 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 18 health-care flour composition of the present invention
By 3.5 kilograms of Hericium erinaceus extracts obtained by embodiment 1 method, 0.2 kilogram of sodium bicarbonate 0.4 liter of water; Take 13 kilograms of wheat flours, 4 kilograms of glutinous rice, 2 kilograms of buckwheats are placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 19 health-care flour composition of the present invention
Take 15 kilograms of wheat flours, 4.5 kilograms of Hericium erinaceus extracts obtained by embodiment 5 method, 0.35 kilogram of sodium bicarbonate, ground and mixed is even, obtains health-care flour composition of the present invention.
the preparation of embodiment 20 health-care flour composition of the present invention
Take 8 kilograms of wheat flours, 1.2 kilograms of Hericium erinaceus extract microcapsules obtained by embodiment 6 method, are placed in container rotating type mixer and mix, and obtain health-care flour composition of the present invention.
the preparation of embodiment 21 health-care flour composition of the present invention
By Hericium erinaceus extract inclusion compound 0.4 liter of water that 3 kilograms obtain by embodiment 7 method; Take 12 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 22 health-care flour composition of the present invention
Take 17 kilograms of wheat flours, 2.8 kilograms of Hericium erinaceus extract inclusion compounds obtained by embodiment 8 method, 0.4 kilogram of sodium bicarbonate, sieves and mixes, and obtains health-care flour composition of the present invention.
the preparation of embodiment 23 health-care flour composition of the present invention
By 0.5 kilogram of Hericium erinaceus extract microcapsules obtained by embodiment 6 method, 0.1 kilogram of sodium bicarbonate, 1.5 kilograms of white sugar 0.2 liter of water; Take 10 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 24 health-care flour composition of the present invention
By 1.3 kilograms of Hericium erinaceus extract inclusion compounds obtained by embodiment 7 method, 0.12 kilogram of sodium bicarbonate, 1.5 kilograms of white sugar 0.3 liter of water; Take 10 kilograms of wheat flours and be placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 25 health-care flour composition of the present invention
By 4.8 kilograms of Hericium erinaceus extract microcapsules obtained by embodiment 9 method, 0.2 kilogram of sodium bicarbonate, 2 kilograms of white sugar 0.6 liter of water; Take 17 kilograms of wheat flours, 1000 grams of glutinous rice flours are placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 26 health-care flour composition of the present invention
By 1.1 kilograms of Hericium erinaceus extract inclusion compounds obtained by embodiment 7,0.15 kilogram of sodium bicarbonate 0.15 liter of water; Take 13 kilograms of wheat flours, 3 kilograms of glutinous rice, 3 kilograms of buckwheats are placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 27 health-care flour composition of the present invention
By 2.5 kilograms of Hericium erinaceus powder, 0.2 kilogram of sodium bicarbonate 0.4 liter of water; Take 15 kilograms of wheat flours, 5 kilograms of glutinous rice, 2 kilograms of buckwheats are placed in fluid bed granulator, both spray combination drying, obtain health-care flour composition of the present invention.
the preparation of embodiment 28 Hericium erinaceus shortbread type biscuit of the present invention
Take the health-care flour composition of the present invention 20 kilograms obtained according to the method for embodiment 10, maltose 0.4 kilogram, milk powder 0.6 kilogram, salt 130 grams, starch 0.6 kilogram, baking powder 50 grams, lard 1.5 kilograms, palm oil 1.5 kilograms.Each material except health-care flour composition of the present invention, starch is dropped in mixer successively, adds water and stir, mixing time 6min; Health-care flour composition of the present invention, starch and water are added in above-mentioned homogeneous material, is stirred to evenly, mixing time 5min, for subsequent use.Whole process adds water 3.5 kilograms altogether.By shaping by mould roll marks for the above-mentioned fabric stirred, cure, obtain semi-finished product biscuit A; Or by shaping by mould roll marks for the above-mentioned fabric stirred, cure, oil spout, obtain semi-finished product biscuit B.Shaping dough sheet by four baking temperature districts, about each district is one point of half the time of staying, bakes 6 min successively altogether.Cure parameter: 1st district: setting face temperature 230 DEG C, setting end temperature 200 DEG C.2nd district: setting face temperature 240 DEG C, setting end temperature 210 DEG C.3rd district: setting face temperature 230 DEG C, setting end temperature 210 DEG C.4th district: setting face temperature 190 DEG C, setting end temperature 200 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.Stove guipure rotating speed: 650cm/min.To baking the oil spout of rear surface of semi-finished sesame oil.Fuel injection parameter: setting oil temperature 65 DEG C, conveyer belt rotating speed 700cm/min.After each semi-finished product biscuit is crossed wafer separator burst, pack, obtain finished product biscuit A and B.
the preparation of embodiment 29 Hericium erinaceus soda cracker of the present invention
Take the health-care flour composition of the present invention 10 kilograms obtained according to the method for embodiment 11,0.18 kilogram is dry yeast, 1.2 kilograms of palm oils, 0.2 kilogram of maltose, 0.1 kilogram of salt.First being dropped into 6 kilograms of flour adjusts in powder cylinders, slowly adds the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 5 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 30 DEG C, ferments 8 hours, completes dough preparing and fermentation for the first time.The dough that first time has fermented is dropped into again and adjusts in powder cylinder, add all the other 4 kilograms health-care flour compositions of the present invention of formula regulation, add grease, maltose and water, start and adjust powder machine, mixed 6min, after dough is formed, be sprinkled into salt again, then modulate 2min, second time dough preparing completes.Poured into by dough in fermentation tank, controlling dough temperature is 32 DEG C, ferments 4 hours.The health-care flour composition of the present invention obtained by embodiment 13 method with 2 kilograms and 0.8 kilogram of palm oil and 0.1 kilogram of salt drop into be adjusted in powder cylinder, is uniformly mixed about 15min, is mixed evenly to material, short, be sub-packed in short dish stand-by.Roll extrusion and lamination folder shortcake.Dough sheet calendering and shaping.Shaping dough sheet by three baking temperature districts, is one point of half the time of staying in each district, bakes 6 min altogether successively.Cure parameter: 1st district: setting face temperature 200 DEG C, setting end temperature 360 DEG C.2nd district: setting face temperature 280 DEG C, setting end temperature 250 DEG C.3rd district: setting face temperature 190 DEG C, setting end temperature 210 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.To baking the oil spout of rear surface of semi-finished coconut oil.Fuel injection parameter: setting oil temperature 50 DEG C is 14% of the weight of finished product by oil mass.Cooling, obtains Hericium erinaceus soda cracker of the present invention, packaging.
the preparation of embodiment 30 Hericium erinaceus soda cracker of the present invention
Take the health-care flour composition of the present invention 10 kilograms obtained according to the method for embodiment 14,0.15 kilogram of yeast, 1.5 kilograms of sesame oil, 0.5 kilogram of coconut oil, 0.3 kilogram of maltose, 0.2 kilogram of salt.First being dropped into by 5 kilograms of health-care flour compositions of the present invention adjusts in powder cylinders, slowly adds the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 6 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 32 DEG C, ferments 6 hours.Complete dough preparing and fermentation for the first time.The dough that first time has fermented is dropped into again and adjusts in powder cylinder, add all the other 5 kilograms health-care flour compositions of the present invention of formula regulation, add grease, maltose and water, start and adjust powder machine, mixed 6min, after dough is formed, be sprinkled into salt again, then modulate 3min, second time dough preparing completes.Poured into by dough in fermentation tank, controlling dough temperature is 30 DEG C, ferments 4 hours.The health-care flour composition of the present invention obtained by embodiment 14 method with 3 kilograms and 300 grams of palm oils and 18 grams of salt drop into be adjusted in powder cylinders, is uniformly mixed about 20min, is mixed evenly to material, short, be sub-packed in short dish stand-by.Roll extrusion and lamination folder shortcake.Dough sheet calendering and shaping.Shaping dough sheet by three baking temperature districts, is one point of half the time of staying in each district, bakes 5 min altogether successively.Cure parameter: 1st district: setting face temperature 200 DEG C, setting end temperature 320 DEG C.2nd district: setting face temperature 250 DEG C, setting end temperature 280 DEG C.3rd district: setting face temperature 180 DEG C, setting end temperature 220 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.To baking the oil spout of rear surface of semi-finished refined coconut oil.Fuel injection parameter: setting oil temperature 60 DEG C is 16% of the weight of finished product by oil mass.Cooling, obtains Hericium erinaceus soda cracker of the present invention, packaging.
the preparation of embodiment 31 Hericium erinaceus wafer of the present invention
Take the health-care flour composition of the present invention 10 kilograms obtained according to the method for embodiment 18, maltose 0.6 kilogram, milk powder 0.4 kilogram, salt 0.1 kilogram, starch 0.3 kilogram, 80 grams, carbonic hydroammonium, vanillic aldehyde 5 grams, Sodium Acid Pyrophosphate 40 grams, sodium pyrosulfite 3 grams, 20 grams, the turbid essence of milk, lard 1.2 kilograms, palm oil 1 kilogram.By the water-soluble solution of Sodium Acid Pyrophosphate and sodium pyrosulfite, for subsequent use; All the other each materials except health-care flour composition of the present invention, starch drop in mixer successively, add water and stir, mixing time 5min; Health-care flour composition of the present invention, starch, the Sodium Acid Pyrophosphate dissolved in advance and sodium pyrosulfite are added in above-mentioned homogeneous material, is stirred to evenly, mixing time 6min, for subsequent use.Whole process shares 4 kilograms, water.By shaping by mould roll marks for the above-mentioned fabric stirred, cure, oil spout.Shaping dough sheet by three baking temperature districts, about each district is one point of half the time of staying, bakes 5 min successively altogether.Cure parameter: 1st district: setting face temperature 230 DEG C, setting end temperature 220 DEG C.2nd district: setting face temperature 230 DEG C, setting end temperature 200 DEG C.3rd district: setting face temperature 220 DEG C, setting end temperature 190 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.Stove guipure rotating speed: 600cm/min.To baking the oil spout of rear surface of semi-finished sesame oil.Fuel injection parameter: setting oil temperature 60 DEG C, conveyer belt rotating speed 600cm/min.
the preparation of embodiment 32 Hericium erinaceus soda cracker of the present invention
Take the health-care flour composition of the present invention 5 kilograms obtained according to the method for embodiment 20,0.1 kilogram of yeast, 0.8 kilogram of palm oil, 80 grams of salt.First health-care flour composition of the present invention and other raw material being dropped into adjusts in powder cylinder, slowly adds the even dirty solution that yeast and suitable quantity of water are modulated into, mixed 8 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 33 DEG C, ferments 4 hours.Dough sheet calendering and shaping.Shaping dough sheet by three baking temperature districts, is one point of half the time of staying in each district, bakes 5 min altogether successively.Cure parameter: 1st district: setting face temperature 200 DEG C, setting end temperature 360 DEG C.2nd district: setting face temperature 250 DEG C, setting end temperature 280 DEG C.3rd district: setting face temperature 180 DEG C, setting end temperature 220 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.To baking the oil spout of rear surface of semi-finished refined coconut oil.Fuel injection parameter: setting oil temperature 55 DEG C is 10% of the weight of finished product by oil mass.Cooling, obtains Hericium erinaceus soda cracker of the present invention, packaging.
the preparation of embodiment 33 Hericium erinaceus soda cracker of the present invention
Take the health-care flour composition of the present invention 15 kilograms obtained according to the method for embodiment 27,0.27 kilogram is dry yeast, 2 kilograms of ready-mixed oils, 1 kilogram of coconut oil, 0.2 kilogram of salt, onion 2 kilograms.Onion is shredded, dry for standby; First being dropped into by 10 kilograms of health-care flour compositions of the present invention adjusts in powder cylinders, slowly adds the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 5 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 31 DEG C, ferments 4 hours.Complete dough preparing and fermentation for the first time.Again being dropped into by the dough that first time has fermented adjusts in powder cylinder, add all the other 5 kilograms health-care flour compositions of the present invention of formula regulation, add grease, onion chip and water, start and adjust powder machine, mixed 6min, after dough is formed, then is sprinkled into salt, modulate 3min again, second time dough preparing completes.Poured into by dough in fermentation tank, controlling dough temperature is 30 DEG C, ferments 4 hours.Dough sheet calendering and shaping.Shaping dough sheet by three baking temperature districts, is about one minute the time of staying in each district, bakes 5 min altogether successively.Cure parameter: 1st district: setting face temperature 200 DEG C, setting end temperature 330 DEG C.2nd district: setting face temperature 250 DEG C, setting end temperature 280 DEG C.3rd district: setting face temperature 180 DEG C, setting end temperature 220 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.To baking the oil spout of rear surface of semi-finished coconut oil.Fuel injection parameter: setting oil temperature 60 DEG C is 16% of the weight of finished product by oil mass.Cooling, obtains Hericium erinaceus soda cracker of the present invention, packaging.
the preparation of embodiment 34 Hericium erinaceus wafer of the present invention
Take the health-care flour composition of the present invention 20 kilograms obtained according to the method for embodiment 16, maltose 1 kilogram, milk powder 0.7 kilogram, salt 0.25 kilogram, starch 0.6 kilogram, 0.1 kilogram, carbonic hydroammonium, vanillic aldehyde 15 grams, Sodium Acid Pyrophosphate 60 grams, sodium pyrosulfite 5 grams, 40 grams, the turbid essence of milk, lard 2 kilograms, 0.5 kilogram, sesame oil, 5 kilograms, egg, cocoa power 0.3 kilogram.By the water-soluble solution of Sodium Acid Pyrophosphate and sodium pyrosulfite, for subsequent use; All the other each materials except health-care flour composition of the present invention, starch drop in mixer successively, add 3.5 premium on currency and stir, mixing time 5min; Health-care flour composition of the present invention, starch, the Sodium Acid Pyrophosphate dissolved in advance and sodium pyrosulfite are added in above-mentioned homogeneous material, is stirred to evenly, mixing time 6min, for subsequent use.By shaping by mould roll marks for the above-mentioned fabric stirred, cure, oil spout.Shaping dough sheet by three baking temperature districts, about each district is one point of half the time of staying, bakes 5 min successively altogether.Cure parameter: 1st district: setting face temperature 230 DEG C, setting end temperature 220 DEG C.2nd district: setting face temperature 230 DEG C, setting end temperature 200 DEG C.3rd district: setting face temperature 220 DEG C, setting end temperature 190 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.Stove guipure rotating speed: 600cm/min.To baking the oil spout of rear surface of semi-finished sesame oil.Fuel injection parameter: setting oil temperature 60 DEG C, conveyer belt rotating speed 600cm/min.
the preparation of embodiment 35 Hericium erinaceus shortbread type biscuit of the present invention
Take the health-care flour composition of the present invention 20 kilograms obtained according to the method for embodiment 19, milk powder 0.6 kilogram, salt 0.2 kilogram, 0.12 kilogram, carbonic hydroammonium, vanillic aldehyde 10 grams, Sodium Acid Pyrophosphate 60 grams, sodium pyrosulfite 8 grams, 3 kilograms, olive oil, celery 4 kilograms.Celery is rolled juice; By the water-soluble solution of Sodium Acid Pyrophosphate and sodium pyrosulfite, for subsequent use; All the other each materials except health-care flour composition of the present invention drop in mixer successively, add 2.5 premium on currency and stir, mixing time 5min; Health-care flour composition of the present invention, the Sodium Acid Pyrophosphate dissolved in advance are added in above-mentioned homogeneous material with sodium pyrosulfite and Celery Juice, is stirred to evenly, mixing time 6min, for subsequent use.By shaping by mould roll marks for the above-mentioned fabric stirred, cure, oil spout.Shaping dough sheet by four baking temperature districts, about each district is one point of half the time of staying, bakes 6 min successively altogether.Cure parameter: 1st district: setting face temperature 235 DEG C, setting end temperature 210 DEG C.2nd district: setting face temperature 240 DEG C, setting end temperature 200 DEG C.3rd district: setting face temperature 235 DEG C, setting end temperature 200 DEG C.4th district: setting face temperature 210 DEG C, setting end temperature 200 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.Stove guipure rotating speed: 600cm/min.To baking the oil spout of rear surface of semi-finished sesame oil.Fuel injection parameter: setting oil temperature 60 DEG C, conveyer belt rotating speed 600cm/min.
the preparation of embodiment 36 Hericium erinaceus shortbread type biscuit of the present invention
Take the health-care flour composition of the present invention 16 kilograms obtained according to the method for embodiment 12, maltose 0.6 kilogram, milk powder 0.3 kilogram, salt 0.2 kilogram, starch 0.5 kilogram, 0.1 kilogram, carbonic hydroammonium, vanillic aldehyde 10 grams, Sodium Acid Pyrophosphate 50 grams, sodium pyrosulfite 6 grams, 30 grams, the turbid essence of milk, 2.5 kilograms, butter, palm oil 1 kilogram.By the water-soluble solution of Sodium Acid Pyrophosphate and sodium pyrosulfite, for subsequent use; All the other each materials except health-care flour composition of the present invention, starch drop in mixer successively, add water and stir, mixing time 6min; Health-care flour composition of the present invention, starch, the Sodium Acid Pyrophosphate dissolved in advance are added in above-mentioned homogeneous material with sodium pyrosulfite and water, is stirred to evenly, mixing time 4min, for subsequent use.Whole process adds water 3 kilograms altogether.By shaping by mould roll marks for the above-mentioned fabric stirred, cure, obtain semi-finished product biscuit A; Or by shaping by mould roll marks for the above-mentioned fabric stirred, cure, oil spout, obtain semi-finished product biscuit B.Shaping dough sheet by four baking temperature districts, is one minute or one point of half the time of staying in each district, bakes 5 min altogether successively.Cure parameter: 1st district: setting face temperature 235 DEG C, setting end temperature 210 DEG C.2nd district: setting face temperature 240 DEG C, setting end temperature 200 DEG C.3rd district: setting face temperature 235 DEG C, setting end temperature 200 DEG C.4th district: setting face temperature 190 DEG C, setting end temperature 200 DEG C.Described temperature is the temperature of biscuit one side upward on conveyer belt; Temperature of the described end is the temperature of biscuit one side down on conveyer belt.Stove guipure rotating speed: 700cm/min.To baking the oil spout of rear surface of semi-finished sesame oil.Fuel injection parameter: setting oil temperature 70 DEG C, conveyer belt rotating speed 560cm/min.After each semi-finished product biscuit is crossed wafer separator burst, pack, obtain finished product biscuit A and B.
the preparation of embodiment 37 Hericium erinaceus bread of the present invention
Take the health-care flour composition of the present invention 15 kilograms obtained according to the method for embodiment 10,0.6 kilogram of dry ferment.First health-care flour composition of the present invention being thrown people adjusts in powder cylinder, slowly adds the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 5 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 28 DEG C, ferments 4 hours.Make little dough, put into bread baking oven baking 20 minutes, obtained hericium erinaceus health-care bread of the present invention.
the preparation of embodiment 38 hericium erinaceus health-care noodles of the present invention
Take the health-care flour composition of the present invention 10 kilograms obtained according to the method for embodiment 13, each 5 kilograms of corn flour, millet powder, salt 0.1 kilogram.Raw material is entered tank and adds suitable quantity of water, uniform stirring, discharging, be fed in flour stranding machine hopper, be shaped by flour stranding machine nip drum, chain conveying vermicelli.Then carry out drying and processing, cut by 24cm length after oven dry and pack.
the preparation of embodiment 39 hericium erinaceus health-care instant noodles of the present invention
Take the health-care flour composition of the present invention 15 kilograms obtained according to the method for embodiment 17, salt 0.15 kilogram.By raw material premix 1 minute, Quick uniform added water and stir about 12 minutes, then low rate mixing 3-4 minute, forms the dough with processing characteristics.The dough of becoming reconciled is put into a slaking dish, 25 DEG C, stir slaking 11 minutes under the condition of rotating speed 6 revs/min.Dough after slaking, again by compound continuous calendering, chopping, forms instant noodles distinctive wavy.Dough after shaping is sent into steam box gelatinization, and wherein noodle feeder temperature arranges 65 DEG C, and outlet temperature arranges 95 DEG C.Again the dough after gelatinization being cut into face block carries out fried, cooling, packaging.
the preparation of embodiment 40 hericium erinaceus health-care steamed bun of the present invention
Take 10 kilograms, the hericium erinaceus health-care flour of the present invention obtained according to the method for embodiment 24,0.5 kilogram is dry yeast.First hericium erinaceus health-care flour of the present invention being thrown people adjusts in powder cylinder, slowly adds the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 5 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 32 DEG C, ferments 6 hours.Make little dough, put into steamer 30 minutes, obtained hericium erinaceus health-care steamed bun of the present invention.
the preparation of embodiment 41 Hericium erinaceus bread of the present invention
Take the health-care flour composition of the present invention 20 kilograms obtained according to the method for embodiment 11,0.8 kilogram of dry ferment.First health-care flour composition of the present invention being thrown people adjusts in powder cylinder, slowly adds the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 7 min after adjusting powder machine to start, dough.Then pour in fermentation tank by dough, controlling dough temperature is 30 DEG C, ferments 4 hours.Make little dough, put into bread baking oven baking 20 minutes, obtained hericium erinaceus health-care bread of the present invention.
the preparation of embodiment 42 Hericium erinaceus cake of the present invention
Take the health-care flour composition of the present invention 10 kilograms obtained according to the method for embodiment 25,0.2 kilogram is dry yeast, 1.2 kilograms of palm oils, 1 kilogram of salad oil, 0.5 kilogram of maltose, baking powder 0.1 kilogram, 0.2 kilogram of salt.15 eggs are cleaned and shells, smash, add 1 kilogram of white sugar, stir 1-2 minute evenly, then high-speed stirring mixes foam-like.Flour of the present invention is thrown people to be adjusted in powder cylinder, and after adjusting powder machine to start, slowly add the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, mixed 5 min, pour into dough in fermentation tank, and controlling dough temperature is 32 DEG C, ferments 4 hours.Add grease, baking powder, maltose, salt, egg and water to fermented dough, start and adjust powder machine, mixed 6min, forms batter.Grilled mold is coated with one deck ready-mixed oil, and the batter modulated is injected grilled mold, and baking, end temperature, face temperature control are made as 180 degree, surface brush one deck palm oil.The demoulding obtains Hericium erinaceus cake of the present invention.
embodiment 43 Hericium erinaceus biscuit is to the protective effect of stomach lining
1. materials and methods
1.1 sample sources:the biscuit that embodiment 28,33,36 obtains, clinical people's consumption is: take biscuit amount every day and be equivalent to 10g crude drug amount.
animal used as test:sD rat, male and female half and half, body weight 180 ~ 220g, is provided by Jiangxi College of Traditional Chinese Medicine Experimental Animal Center, SCXK (Jiangxi) 2006-0001.
main agents:indomethacin tablet: south China, Guangzhou medicine company Group Co., Ltd, lot number: 20080614; Formaldehyde: Tianjin Chemical Co., Ltd.'s all generations, lot number: 091025; Glacial acetic acid: Guangzhou Chemical Reagent Factory is produced, lot number: 20081006, ethanol: Tianjin Chemical Co., Ltd.'s all generations, lot number: 090225.
key instrument:table-type high-speed refrigerated centrifuge (Thermo, the U.S.); Electronic balance (1/10,1/100,1/10000, Mei Tele company); Gilson pipettor (Gilson, France).
experimental technique
2. the 1 pair of ethanol causes the protective effect of gastric mucosa damagerat is divided into model control group at random, Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, dosage is 1.0g crude drug/kg), often organizes 10 animals.Every day gastric infusion 1 time, administration capacity is 10ml/kg, and continuous 7 d, model control group gives equivalent distilled water.First fasting 48 h of rat before experiment, freely drink water, 1 h every rat oral gavage absolute ethyl alcohol 1 mL/only after last administration, takes off cervical vertebra after 1 h and puts to death animal, folder closes orifice of the stomach, inject 1% formaldehyde 5 mL from pylorus, then folder closes pylorus, puts into 1% formalin and fixes 10 min, coat of the stomach is cut off along greater curvature, measure damaged length, as gastric mucosal damage index, and calculate inhibiting rate using damaged length (width is greater than 1 mm to be doubled) summation.Inhibiting rate (%)=(control group UI-administration group UI) ÷ control group UI × 100%
2. the 2 pairs of indocins cause the protective effect of gastric mucosa damagegrouping and administration are with 2.1.Rat Fast 24 h before experiment, freely drink water, 1 h every rat skin lower injection indocin 30mg/kg after last administration, after 7 h, de-cervical vertebra puts to death animal, folder closes orifice of the stomach, inject 1% formaldehyde 5 mL from pylorus, then folder closes pylorus, puts into 1% formalin and fixes 10 min, coat of the stomach is cut off along greater curvature, measure damaged length, as gastric mucosal damage index, and calculate inhibiting rate using damaged length (width is greater than 1 mm to be doubled) summation.
glacial acetic acid is caused to the protective effect of gastric mucosa damagegrouping and administration are with 2.1.Animal fasting 24 h before experiment, freely drinks water.With 10% chloraldurate 3. 5 mL/kg anesthetized animal, open abdomen, gently pull out stomach after belly sterilization under xiphoid-process, under 30% glacial acetic acid 50 μ L being injected to glandular stomach portion antetheca hole body intersection serous coat, abdominal incision is sewed up in layering.Postoperative animal routine is raised, start to tested material postoperative next day, 1 time/d, continuous 14 d, control group gives isometric(al) distilled water, and after last administration, 24 h (fasting) put to death animal, measure and calculate ulcer index, represent UI by the most major diameter of ulcer and the average of most minor axis, carry out statistical procedures, compare group difference.Ulcer healing rate (%)=(control group diameter average summation-administration group ulcer diameter average summation) ÷ control group diameter average summation × 100%
2.4 statistical method: experimental data with
represent, adopt one-way analysis of variance, the difference between more each group, P<0.05 is judged as that difference has conspicuousness, and P<0.01 is judged as that difference has pole conspicuousness.
result
3.1 pairs of ethanol cause the protective effect of gastric mucosa damageresult, as shown in table 1, compares with model control group, and Hericium erinaceus biscuit is respectively organized and all can be reduced ethanol and cause gastric mucosa damage index.
indocin is caused to the protective effect of gastric mucosa damageresult is as shown in table 2, compares with model control group, and Hericium erinaceus biscuit is respectively organized and all can be reduced indocin and cause gastric mucosa damage index.
3.3 pairs of glacial acetic acid cause the protective effect of gastric mucosa damageresult is as shown in table 3, compares with model control group, and Hericium erinaceus biscuit is respectively organized and all can be reduced glacial acetic acid and cause gastric mucosa damage index.
conclusion:
Animal experiment study shows: Hericium erinaceus biscuit has good protective effect to the acute and chronic gastritis mucosa injury caused by ethanol, indocin, glacial acetic acid.
embodiment 44 Hericium erinaceus biscuit is to the auxiliary therapeutic action of chronic gastritis
1. materials and methods
1.1 sample sources:with embodiment 43.
animal used as test:sD rat, male and female half and half, body weight 180 ~ 220g, is provided by Jiangxi College of Traditional Chinese Medicine Experimental Animal Center, SCXK (Jiangxi) 2006-0001.
main agents:sanjiu weitai capsules electuary is brown granular, and counter proprietaries, is dissolved in water before use.NaTDC, Beijing extensive and profound in meaning star biotechnology responsibility Co., Ltd produces, lot number: 20080206; Formaldehyde: Tianjin Chemical Co., Ltd.'s all generations, lot number: 091025; Ethanol: Tianjin Chemical Co., Ltd.'s all generations, lot number: 090225.
key instrument:table-type high-speed refrigerated centrifuge (Thermo, the U.S.); Electronic balance (1/10,1/100,1/10000, Mei Tele company); Gilson P type pipettor (Gilson, France).
experimental technique
2. 1 grouping, modeling and administrationrat is divided into 6 groups, i.e. blank group, model control group, sanjiu weitai capsules (0.6g/kg)+Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, 1.0g crude drug/kg), sanjiu weitai capsules group (0.6g/kg), often organizes 10, male and female half and half.After buying 1 week, except Normal group, all the other each treated animals every 5 days at 1st month 2ml/ gavage 60% ethanol 1 time, every day replaces running water freely to drink with 20mmol/ L deoxycholic aicd sodium water solution; Once, every day replaces running water freely to drink to animal with 20mmol/ L deoxycholic aicd sodium water solution to 2nd month every 7 days 2ml/ gavage 60% ethanol; Within three month, running water was replaced freely to drink to animal with 30% ethanol water and 20mmol/ L deoxycholic aicd sodium water solution in turn every 3 days.Distilled water is gavaged every day, administration group difference gavage every day relative medicine totally 90 days from experiment beginning day pattern drawing control group and blank group.
testing indexfasting 16 hours after last administration, the descending pyloric ligation of rat etherization, after 6 hours, etherization is lethal.Open abdominal cavity, clamp orifice of the stomach (preventing gastric juice from flowing out) with haemostatic clamp, take out full stomach.First wash surperficial crimson blood off with distilled water, blot water with filter paper, then cut off body of stomach along greater curvature and take out gastric juice, with graduated cylinder amount gastric juice volume; Gastric juice pH value is determined with pH measurement; Get gastric juice supernatant and measure pepsin and total acidity gastric juice; Gastric tissue 10% formaldehyde fixedly makes pathologic finding.Centrifugal 8 minutes of gastric juice 3000rpm, get supernatant 011ml, add 0.5% bSA 1ml (with 0.01N HCl preparation), 37 DEG C of water bath heat preservations add 2ml 10% TCA after 20 minutes, centrifugal 15 minutes of 3000rpm, gets supernatant 0.1ml and adds 10%Na
2cO
30.9ml, 1N phenol reagent 0.5ml, room temperature places 20 minutes, wavelength 660nm colorimetric, surveys pepsin content (taking tyrosine as standard).Get supernatant 1ml with phenolphthalein indicator 1, with 0.01N NaOH titration, record consumes NaOH ml quantity, calculates total acidity gastric juice value.
on the impact of chronic gastritis rat pathological changealong lesser curvature from glandular stomach to pylorus clip 3 × 10mm
2holostrome coat of the stomach 4 pieces, fix with 10% formalin, paraffin inclusion, section, HE dyes, and with the pathological change in om observation glandular stomach and gland division and hole portion, scores by the grading of pathology, according to the visual field number observed in section, averages and compares.Degree of inflammation divides 4 grades (0 ~ 4): (0) NIP; (+) has the inflammatory cell be dispersed in individually at body of gland or bottom; (++) all has more inflammatory cell at body of gland each several part; The cell infiltration stove that (+++) has gathering in heaps.Tissue content with the thickness of muscular layer of mucosa for mark, by muscular layer of mucosa and on it thickness proportion of gastric mucosa carry out com-parison and analysis.
statistical method: experimental data with
represent, adopt one-way analysis of variance, the difference between more each group, P<0.05 is judged as that difference has conspicuousness, and P<0.01 is judged as that difference has pole conspicuousness.
result
the change of 3.1 gastric juice volumes and pH valueresult, as shown in table 1, compares with model control group, and sanjiu weitai capsules+embodiment 28 groups, sanjiu weitai capsules+embodiment 33 groups, sanjiu weitai capsules+embodiment 36 groups of gastric secretions increase, and pH value declines; Hericium erinaceus biscuit all obviously can increase the facilitation of sanjiu weitai capsules to gastric acid secretion.
the change of gastric acidity and peptic activity of stomachresult is as shown in table 2, compares with model control group, and sanjiu weitai capsules group, sanjiu weitai capsules+embodiment 28 groups, sanjiu weitai capsules+embodiment 33 groups, sanjiu weitai capsules+embodiment 36 groups of gastric acidities increase, and peptic activity of stomach raises; Hericium erinaceus biscuit all obviously can promote that sanjiu weitai capsules is to the effect that gastric acidity increases and peptic activity of stomach raises.
on the impact of chronic gastritis rat pathological changethe results are shown in Table 3,4.The gastric mucosa surface flat smooth of normal rats, pink, glossy, the surface epithelial cell of histotomy display glandular stomach has thick mucus, the lymphocyte be dispersed on a small quantity as seen once in a while under mucous membrane and in muscle layer.The body of stomach degree of inflammation of the Rat Experimental gastritis of bringing out with deoxysodium cholate and alcohol obviously increases the weight of, and has volume lymphocyte and polymorphonuclear leukocyte in the lamina propria between gastric gland; There is the cell infiltration stove that many places are larger in most animals stomach hole, the gastric gland at some position shortens or gland spacing broadens.The body of stomach of sanjiu weitai capsules+Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups) and the degree of inflammation in stomach hole portion is all obvious than model control group alleviates.
conclusion:
Animal experiment study shows: Hericium erinaceus biscuit can increase sanjiu weitai capsules and increase chronic gastritis rat stomach liquid acidity and peptic activity of stomach rising, promote that sanjiu weitai capsules increases chronic gastritis rat stomach liquid acidity and peptic activity of stomach raises, improve chronic gastritis rat pathological change, therefore have the effect of supplemental treatment gastritis.
.
embodiment 45 Hericium erinaceus biscuit is to the auxiliary therapeutic action of Experimental Gastric Ulcer in Rats
1. materials and methods
1.1 sample sources:with embodiment 43
1.2 animals used as test:sD rat, male and female half and half, body weight 180 ~ 220g, is provided by Jiangxi College of Traditional Chinese Medicine Experimental Animal Center, SCXK (Jiangxi) 2006-0001.
main agents:formaldehyde: Tianjin Chemical Co., Ltd.'s all generations, lot number: 091025; Ethanol: Tianjin Chemical Co., Ltd.'s all generations, lot number: 090225.Ranitidine hydrochloride capsules, Desheng, Fujian pharmaceutcal corporation, Ltd, lot number: 080505; Glacial acetic acid, Shanghai reagent one factory produces, lot number: 20316.
key instrument:xT S-110 bitubular disecting microscope, Chongqing optical instrument factory; Table-type high-speed refrigerated centrifuge (Thermo, the U.S.); Electronic balance (1/10,1/100,1/10000, Mei Tele company); Gilson P type pipettor (Gilson, France).
experimental technique
2. 1 impact on stress in rats gastric ulcerchoose rat 50, be divided into 5 groups at random, be i.e. model control group, ranitidine (0.15g/kg)+Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, 1.0g crude drug/kg), ranitidine group (0.15g/kg), often organize 10, male and female half and half.Ig administration respectively, administration every day 1 time, after totally 7 last administrations, the binding of rat four limbs is fixed on wire netting by 0. 5 h, in head is upwards dipped vertically into (23 ± 1) DEG C water, water logging is to mouse xiphoid-process position, after soaking 8 h, rat is put to death, opens abdomen, ligation pylorus and orifice of the stomach, 1% formalin 1mL is injected in stomach, and stomach is dipped in 10min in 1% formalin solution, cut off stomach along greater curvature, wash away gastric content, stomach lining is faced up and flattens on glass plate, under disecting microscope, count UI and the ulcer inhibition rate of the appearance of glandular stomach portion.Stress gastric ulcer index calculation method: ulcer point or face 1 below mm person count 1 minute; 1 ~ 2 mm person, counts 2 points; 2 ~ 3 mm persons count 3 points; 3 ~ 4 mm persons count 4 points; Be greater than 4 mm persons and count 5 points, score is added the UI being this animal.Ulcer inhibition rate (%)=(control group UI-administration group UI) ÷ control group UI × 100%.
rat acetic acid is burnt to the impact of gastric ulcerrat under etherization opens abdomen, and expose stomach, before glandular stomach portion on hole body intersection serosal surface, the diameter sticking glacial acetic acid is round filter paper 30 s of 5 mm, reduction stomach, sews up coat of the stomach.Animal is divided into 5 groups by postoperative 24 h at random, grouping and medication together 2.1, every day gavage 1 time, successive administration 10 d.After last administration, 24 h are by sacrifice of animal, cut open stomach, under anatomical lens, measure ulcer area.
on the impact of pylorus-ligated rats hydrochloric acid in gastric juice amountrat is divided into model control group at random, Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, 1.0g crude drug/kg), often organizes 10 animals.Every day gastric infusion 1 time, administration capacity is 10ml/kg, and continuous 7 d, model control group gives equivalent distilled water.Animal fasting 48 h before experiment, freely drinks water.During experiment with ether by animal light anesthesia, under ensiform process of sternum, cut off stomach wall 2 ~ 3 cm along ventrimeson, by stomach gently hook go out, at stomach pylorus underpass and by pylorus ligation, and in duodenal administration 1 time, control group gives equivalent distilled water.Suturing them otch.The single cage of postoperative rat is raised fasting and is prohibited water, and Post operation 5 h cervical dislocation puts to death animal, opens abdominal cavity ligation orifice of the stomach, win full stomach, clean bloodstain with filter paper, cut off coat of the stomach along greater curvature, incline and content, be collected in graduated centrifuge tube, record gastric juice amount, then with 1 500 r/min centrifugation 10 min, get supernatant 1 mL, measure gastric acidity with acid-base value analyzer, and measure gastric juice peptic activity of stomach.
on the impact that gastric acid secretion caused by histamine increasesgrouping and administration are with 2.3.Rat Fast 24 h before experiment, freely drink water, urethane 1.25g/k g anaesthetizes, and back of the body position is fixed, trachea cannula.In stomach, insert internal diameter 3 m m vinyl tube through duodenum by stomach pylorus after opening abdomen, after ligation, in stomach, insert from oral cavity through orifice of the stomach the same plastic tube be connected with perfusion device again.With (till flowing out without gastric content) after the hydrochloric acid Saline perfusion liquid gastric lavage of pH 4, adjustment perfusion rate is that 5 m l/ min carry out constant speed perfusion.Administration group is given 1 time from duodenum, and control group gives capacity physiological saline respectively.After administration during 20 min, each mouse respectively subcutaneous excitants histamine 10 m g/k g that gives is accessed the perfusate given after excitants in 60min by pylorus intubate, measure gastric acidity, and measure gastric juice peptic activity of stomach with acid-base value analyzer.
statistical method: experimental data is with `
represent, adopt one-way analysis of variance, the difference between more each group, P<0.05 is judged as that difference has conspicuousness, and P<0.01 is judged as that difference has pole conspicuousness.
result
3.1 impacts on stress in rats gastric ulceras shown in table 1, compare with model control group, ranitidine group, ranitidine+Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups) UI obviously reduces; Hericium erinaceus biscuit all obviously can increase the reducing effect of ranitidine to ulcer index.
rat acetic acid is burnt to the impact of gastric ulceras shown in table 2, compare with model control group, ranitidine group, ranitidine+Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups) ulcer area obviously reduces; Hericium erinaceus biscuit all obviously can increase the inhibitory action of ranitidine to gastric ulcer area.
on pylorus-ligated rats hydrochloric acid in gastric juice and pepsic impactresult is as shown in table 3, compares with model control group, and Hericium erinaceus biscuit group (i.e. embodiment 28,333,36 groups) all can suppress the secretion of pylorus-ligated rats hydrochloric acid in gastric juice, reduces its pepsin activity.
on the impact that gastric acid secretion caused by histamine increasesresult is as shown in table 4, compares with model control group, and Hericium erinaceus biscuit group (i.e. embodiment 28,33,336 groups) has obvious inhibitory action to the gastric acid secretion increase caused by histamine.
conclusion:
Animal experiment study shows: Hericium erinaceus biscuit can increase the effect that ranitidine stress gastric ulcer rat and acetic acid burn gastric ulcer rat ulcer exponential sum ulcer area, the gastric acid secretion of Hericium erinaceus biscuit to pylorus-ligated rats has inhibitory action, also the gastric acid secretion caused by histamine can be suppressed to increase simultaneously, therefore have the effect of supplemental treatment gastric ulcer.
embodiment 46 Hericium erinaceus biscuit is to the inhibitory action of helicobacter pylori
1. materials and methods
1.1 sample sources:with embodiment 43.
animal used as test:healthy adult Balb/c mouse 60, in 6 week age, body weight 16g ~ 18g, male and female half and half, purchased from Institute of Experimental Animals, Chinese Academy of Medical Sciences, credit number is: scxk capital 2004-0001.
main agents:the Hpy lori bacterial strain adopted is Sydney reference culture of international uniform, through identifying this bacterial strain CagA (+) and VacA (+).
key instrument:table-type high-speed refrigerated centrifuge (Thermo, the U.S.); Electronic balance (1/10,1/100,1/10000, Mei Tele company); Gilson pipettor (Gilson, France).
experimental technique
2. inhibitory action in 1 pair of Hpylori body
2. 1. 1 animal modelsgive before mouse experiment in drinking-water and add Fresh antibiotic mixed liquor, Dose standard is gentamicin 15mg/kg, ampicillin 100 mg/kg, drinks 5d continuously and carries out antibiotic pretreatment, modeling is started, modeling method: after fasting 24h, give 2% NaHCO after drug withdrawal 5d
3a solution 0. 2m l/gavage, give after 1h Hpylo ri fresh suspendible bacterium liquid (
) a 0. 2m l/ gavage, recover normal diet after 1h, the next day 1 time, totally 5 times.
modeling success evaluationafter giving Hpylo ri fresh suspendible bacterium liquid gavage for the last time, 24h extracts 10 sacrifice of animal immediately, sterile working is cut open the belly and is got stomach, cut off along greater curvature, get gastric antrum pylorus portion tissue and do urease test (RUT), positive rate is 100% display modeling success.
animal grouping and administrationanimal is divided into model control group, Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, 2.0g crude drug/kg) at random, totally 4 groups after modeling success, often organizes 10.Give relative medicine respectively, every day 1 time, model group gives same volume physiological saline, continuous 7 days.
indexs measureafter last gavage, 24h puts to death animal, and sterile working is cut open the belly and got stomach, cuts off along greater curvature, gets gastric antrum pylorus portion tissue and does gastric mucosa gram stain smear microscopy and look for Hpylori and RUT to test.
to Hpylori In-vitro Inhibitory Effect
2. 1 tested liquor strength preparationsbe dissolved in sterile distilled water by extract obtained for embodiment 5, carry out two-fold dilution and get its concentration, be respectively 1,0. 5,0. 25,0. 125,0. 0025,0. 0313,0. 0156,0. 0078,0. 0039g crude drug/m l.
prepared by drug paper diskfilter paper card punch is broken into diameter 6mm size, autoclave sterilization, add after soaking 2h in above-mentioned variable concentrations liquid respectively, drying for standby.
antibacterial observation(concentration is to dip Hpylori bacterium liquid with sterile cotton test paper
cFU/m l) be coated with whole media surface, ensure that coating is evenly.Hold the filter paper got containing above variable concentrations medicine with aseptic tweezer respectively under the arm, be attached to the surface of the agar plate of inoculated with Hp ylori, physiological saline filter paper compares, and on each flat board between each scraps of paper, the scraps of paper and plate edge are all evenly distributed.After cultivating 72h under 37 DEG C of micro-aerobic environments, observe the presence or absence of inhibition zone, by its diameter of vernier caliper measurement.Be extremely sensitive with bacteriostatic diameter > 10mm, 7mm
< bacteriostatic diameter < 10mm is medium sensitivity, and 2mm< bacteriostatic diameter <7mm is less sensitive, and bacteriostatic diameter < 2mm is insensitive is criterion.
statistical method: experimental data is with `
represent, adopt one-way analysis of variance, the difference between more each group, P<0.05 is judged as that difference has conspicuousness, and P<0.01 is judged as that difference has pole conspicuousness.Enumeration data compares employing X between any two
2inspection.
result
the therapeutic action of 3.1 pairs of Hpylori infecting mousesresult, as shown in table 1, compares with model control group, and Hericium erinaceus biscuit group significantly can reduce Hpylori infecting mouse Hpylori smear-positive number and RUT number positive.
to Hpylori In-vitro Inhibitory Effectresult is as shown in table 2, compares with model control group, and Hericium erinaceus 0.0625 ~ 1.0g crude drug/ml has the bacteriostasis of moderate and height to Hpylori, and Hericium erinaceus 0.0156 ~ 0.0313g crude drug/ml has low bacteriostasis to Hpylori.
conclusion:
Research shows: Hericium erinaceus biscuit has in good body and the effect of external suppression helicobacter pylori.
embodiment 47 Hericium erinaceus biscuit alleviates the research of abdominal pain
1. materials and methods
1.1 sample sources:with embodiment 43.
animal used as test:kunming mouse, male and female half and half, body weight 18 ~ 22g, is provided by Jiangxi College of Traditional Chinese Medicine Experimental Animal Center, SCXK (Jiangxi) 2005-0001.
main agents:rotundine sheet, Sichuan Kang Fu comes medicine company Group Co., Ltd, lot number: 20080322; Glacial acetic acid: Guangzhou Chemical Reagent Factory is produced, lot number: 20081006; Metoclopramide sheet, Jinan gold is safe, and pharmaceutical factory produces, lot number: 070906.
key instrument:table-type high-speed refrigerated centrifuge (Thermo, the U.S.); Electronic balance (1/10,1/100,1/10000, Mei Tele company); Gilson pipettor (Gilson, France); 722 grating spectrophotometers,
Shanghai the 3rd analytical instrument factory.
experimental technique
2. 1 the impact that Dichlorodiphenyl Acetate causes mouse writhing to reactmouse 50, male and female half and half, are divided into 5 groups at random, often organize 10, i.e. blank group, Rotundine group (60 mg/kg), Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, 2.0g crude drug/kg), often organize 10, ig administration respectively, continuous 7 days, 1 h after administration, each mouse is ip 0.6% glacial acetic acid 0.2 mL respectively, each mouse writhing response number of times in 15 min after record injection algogen.
the impact emptying on Mouse Stomachmouse is divided into blank group, Hericium erinaceus biscuit group (i.e. embodiment 28,33,36 groups, 2.0g crude drug/kg) at random, metoclopramide group (0. 01 g/kg).Gavage liquid every day 1 time, continuous 7d, then water 18 h is can't help in fasting, 1 h after administration on the 7th, the equal gavage pastel of each group (10 g carboxymethyl celluloses, 16 g milk powder, 8 g sugar, 8 g starch, be dissolved in distilled water, be made into the pastel of 1mL about 1 g), every mouse 1mL, 40 m in take off cervical vertebra execution mouse afterwards, cut open the belly, ligation stomach orifice of the stomach and pylorus, taking-up stomach filter paper claims full weight after wiping and doing, then cut off body of stomach along greater curvature, wipe dry after washing out gastric content, claim stomach net weight.Subtract the difference of stomach net weight with stomach full weight for residue weight in stomach, this heavy with give that to stick with paste heavy (be 1 percentage g) by 1mL be residual rate in stomach.
statistical method: experimental data is with `
represent, adopt one-way analysis of variance, the difference between more each group, P<0.05 is judged as that difference has conspicuousness, and P<0.01 is judged as that difference has pole conspicuousness.
result
the impact that 3.1 Dichlorodiphenyl Acetates cause mouse writhing to reactresult, as shown in table 1, compares with blank group, and Hericium erinaceus biscuit group all can reduce mouse writhing reaction times.
the impact emptying on Mouse Stomachresult is as shown in table 2, compares with blank group, and Hericium erinaceus biscuit group all can reduce gastric content residual rate.
conclusion:
Animal experiment study shows: Hericium erinaceus biscuit can reduce acetic acid induced mice writhing number of times, reduces gastric content residual rate, and prompting Hericium erinaceus biscuit has relieving spasm and pain effect, can be used for alleviating gastritis and the abdominal pain caused by ulcer.
Claims (32)
1. the food be made up of health-care flour composition, is characterized in that described health-care flour composition is made up of following raw material: flour 100 weight portion, Hericium erinaceus 1 ~ 30 weight portion; Wherein Hericium erinaceus is one of following:
(1) ultramicro grinding to 350 ~ 500 order;
(2) Hericium erinaceus fresh goods or dry product raw material add water and/or alcohol extracting obtains Hericium erinaceus extract;
(3) Hericium erinaceus fresh goods or dry product raw material add water and/or the Hericium erinaceus extract that obtains of extract drying after alcohol extracting;
(4) Hericium erinaceus fresh goods or dry product raw material add water and/or alcohol extracting, and extraction gained material is carried out inclusion obtain Hericium erinaceus extract inclusion compound or microcapsules, the inclusion agents that wherein inclusion compound uses is selected from cyclodextrin, and microcapsules capsule material is selected from one or more in gelatin, converted starch, natural plant gum, alginic acid.
2. food according to claim 1, is characterized in that: one of the in the following manner process of Hericium erinaceus dry product or new fresh Hericium erinaceus:
(1) pulverized 40 ~ 80 mesh sieves with pulverizer, obtained crude product, then through ultracentrifugation beveller, pulverize 10 ~ 20min under 12000/min ~ 16000r/min condition, obtain 350 ~ 500 order Ultramicro-powders;
(2) add water and/or after alcohol extracting, be concentrated into proportion 1.02 ~ 1.10, obtaining Hericium erinaceus extract;
(3) add water and/or be concentrated into proportion 1.02 ~ 1.10 after alcohol extracting, drying obtains Hericium erinaceus extract;
(4) to add water and/or alcohol extracting, extract is concentrated into proportion 1.02 ~ 1.10, and gained material carries out inclusion and obtains Hericium erinaceus extract inclusion compound or microcapsules.
3. food according to claim 2, is characterized in that: one of the in the following manner process of Hericium erinaceus dry product or new fresh Hericium erinaceus:
(1) pulverize 40 ~ 80 mesh sieves with pulverizer, obtained crude product, then pulverized 10 ~ 20 min under ultracentrifugation beveller 12000r/min ~ 16000r/min condition, obtain 350 ~ 500 order Ultramicro-powders;
(2) add water and/or after alcohol extracting, be concentrated into proportion 1.04 ~ 1.07, obtaining Hericium erinaceus extract;
(3) add water and/or be concentrated into proportion 1.04 ~ 1.07 after alcohol extracting, drying obtains Hericium erinaceus extract;
(4) to add water and/or alcohol extracting, extract is concentrated into proportion 1.04 ~ 1.07, and gained material carries out inclusion and obtains Hericium erinaceus extract inclusion compound or microcapsules.
4. food according to claim 3, is characterized in that:
(1) water extraction is pulverized by Hericium erinaceus raw material, adds weight ratio 10 ~ 20 times of soak by water 1 ~ 3 time, each 1 ~ 2 hour, merge decoction liquor, concentrate to obtain Hericium erinaceus extract after filtering; Dry Hericium erinaceus extract;
(2) alcohol extracting is pulverized by Hericium erinaceus raw material, adds weight ratio 3 ~ 8 times of alcohol dipping 15 ~ 35 days; Or alcohol reflux extracts 1 ~ 3 time, each 2 ~ 4 hours, maceration extract or extract reclaim ethanol, concentrate to obtain Hericium erinaceus extract; Dry Hericium erinaceus extract.
5., according to the arbitrary described food of Claims 1 to 4, it is characterized in that: flour is selected from but is not limited to one or more powder made for raw material grinding mill in wheat, corn, rice, millet, barley, jowar, the seed of Job's tears, oat, buckwheat, naked oats, pumpkin, the root of kudzu vine, potato, cassava, soya bean, red bean, mung bean, kidney bean, broad bean, pea, cowpea, chick-pea, lotus root, water caltrop, lily, konjaku, banana dasheen.
6. food according to claim 5, is characterized in that: flour is wheat flour.
7. food according to claim 1, is characterized in that: cyclodextrin is selected from alpha-cyclodextrin, beta-schardinger dextrin-, gamma-cyclodextrin or their derivative.
8. food according to claim 1, is characterized in that: described health-care flour composition is further containing leavening agent 0.1 ~ 2.5 weight portion.
9. food according to claim 8, is characterized in that: described health-care flour composition is further containing sweetener 1 ~ 35 weight portion.
10. food according to claim 9, is characterized in that containing: flour 100 weight portion, Hericium erinaceus 5 ~ 20 weight portion, leavening agent 0.5 ~ 1.5 weight portion, sweetener 5 ~ 20 weight portion.
11. food according to claim 9, is characterized in that containing: flour 100 weight portion, Hericium erinaceus 3 ~ 7 weight portion, leavening agent 0.5 ~ 1.5 weight portion, sweetener 15 ~ 30 weight portion.
12. food according to claim 8, wherein said leavening agent is selected from one or more in sodium bicarbonate, baking powder, ammonia bicarbonate, alum, sodium pyrosulfite, Sodium Acid Pyrophosphate, yeast.
13. food according to claim 9, wherein said sweetener is selected from one or more in glucose, fructose, sucrose, maltose, starch sugar, lactose, stevioside, Aspartame, 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one 2,2-dioxide potassium salt, saccharin sodium, honey element, maltitol.
14. food according to claim 9, is characterized in that: health-care flour composition is further containing one or more in vitamin, starch, salt, five-spice powder, monosodium glutamate, milk powder, stearoyl lactate, disodium ethylene diamine tetraacetate.
15. food according to claim 1, is characterized in that: health-care flour composition adds one or more in the vitamin of 0.2 ~ 10 weight portion, starch, salt, five-spice powder further.
16. food according to claim 1, is characterized in that: health-care flour composition is further containing one or more in the milk powder of 0.02 ~ 5 weight portion, essence, stearoyl lactate, disodium ethylene diamine tetraacetate.
17., according to Claims 1 to 4 or 5 ~ 16 arbitrary described food, is characterized in that: be biscuit, bread, instant noodles, steamed bun, noodles or cake.
18. food according to claim 17, is characterized in that: by health-care flour composition fatten, flavoring essence and water, make shortbread type biscuit or soda cracker.
19. food according to claim 18, is characterized in that: grease includes but not limited to one or more in butter, butter, lard, shortening, edible vegetable oil.
20. food according to claim 19, is characterized in that: one or more in the preferred coconut oil of vegetable oil, palm oil, olive oil, salad oil, peanut oil, tea-seed oil, soya-bean oil, sesame oil, long beggar's oil.
21. food according to claim 18, is characterized in that the raw material containing following weight parts is made: 100 parts, flour, Hericium erinaceus 1 ~ 30 part, leavening agent 0.1 ~ 2.5 part, sweetener 1 ~ 35 part, grease 10 ~ 30 parts, salt 0.6 ~ 2 part, flavoring essence 0.02 ~ 5 part, 10 ~ 30 parts, water.
The arbitrary described food of 22. claims 17 or 18 ~ 21, is characterized in that: described food is biscuit, is coated with chocolate cream, jam or other tartar sauce and makes sandwich biscuits or decoration biscuit between biscuit monolithic.
23. food according to claim 18, is characterized in that the preparation method of shortbread type biscuit comprises the following steps:
(1) dough is modulated: take each raw material by described composition of raw materials: first sweetener and grease are mixed to get material A; By leavening agent, salt, flavoring essence mixing, and the material B that is dissolved in water to obtain; Material A, material B, Hericium erinaceus, other raw material and water are dropped in mixer successively, is stirred to evenly; Then by flour and the mixing of above-mentioned homogeneous material, add water and continue to be stirred to evenly, for subsequent use;
(2) compressing: the biscuit green compact being made various shape through shaping mechanism;
(3) cure: biscuit green compact are sent into curer baking, burner hearth is divided into four districts: 1 setting face, district temperature 220 ~ 235 DEG C, end temperature 200 ~ 220 DEG C; 2 setting face, district temperature 230 ~ 250 DEG C, end temperature 190 ~ 210 DEG C; 3 setting face, district temperature 230 ~ 240 DEG C, end temperature 200 ~ 210 DEG C; 4 setting face, district temperature 160 ~ 200 DEG C, end temperature 170 ~ 210 DEG C; Wholely cure 4 ~ 8 minutes time;
(4) oil spout: biscuit is come out of the stove rear surface oil spout;
(5) pack: by the biscuit after oil spout through arranging, packaging, finished product.
24. food according to claim 18, is characterized in that the preparation method of soda cracker comprises the following steps:
(1) dough preparing and fermentation: first flour, Hericium erinaceus are dropped into and adjust in powder cylinder, then add grease, sweetener, salt, sodium bicarbonate, flavoring essence and other raw material; After adjusting powder machine to start, slowly add the even dirty solution that i.e. dry yeast and suitable quantity of water are modulated into, be blended into dough, then dough poured in fermentation tank and ferment;
(2) dough sheet calendering and shaping: through stamped or rolling cut dough sheet, cut out the biscuit green compact of different appearance profile;
(3) cure: biscuit green compact are sent into curer baking, burner hearth is divided into three districts: 1 setting face, district temperature 190 ~ 210 DEG C, end temperature 320 ~ 360 DEG C; 2 setting face, district temperature 240 ~ 280 DEG C, end temperature 230 ~ 250 DEG C; 3 setting face, district temperature 180 ~ 220 DEG C, end temperature 180 ~ 220 DEG C; Wholely cure 5 ~ 10 minutes time;
(4) oil spout: biscuit is come out of the stove rear surface oil spout;
(5) pack: by the biscuit after oil spout through arranging, packaging, finished product.
25. food according to claim 1, wherein health-care flour composition is made up of following raw material: Hericium erinaceus extract 10 ~ 12 weight portion that the extract drying after wheat flour 100 weight portion, Hericium erinaceus dry product extracting in water obtains.
26. food according to claim 1, wherein health-care flour composition is made up of following raw material: wheat flour 15 weight portion, Hericium erinaceus extract 2.3 weight portion that the extract drying after Hericium erinaceus dry product adds alcohol extracting obtains.
27. food according to claim 1, wherein health-care flour composition is made up of following raw material: wheat flour 12 weight portion, Hericium erinaceus extract 2.9 weight portion that the extract drying after Hericium erinaceus dry product adds alcohol extracting obtains.
28. food according to claim 1, wherein health-care flour composition is made up of following raw material: wheat flour 100 weight portion, Hericium erinaceus extract inclusion compound or microcapsules 5 ~ 25 weight portion.
29. food according to claim 1, wherein health-care flour composition is made up of following raw material: wheat flour 100 weight portion, and Hericium erinaceus adds extract 20 ~ 30 weight portion obtained after drying after alcohol and water extracts.
Food described in 30. any one of claim 1-29 has the purposes of repairing in the gastric mucosa injure food that causes of chronic gastritis, gastric ulcer or duodenal ulcer in preparation.
Food described in 31. any one of claim 1 ~ 29 has the purposes suppressed in helicobacter pylori food in preparation.
The purposes had in the food of supplemental treatment chronic gastritis, gastric ulcer or duodenal ulcer prepared by food described in 32. any one of claim 1 ~ 29.
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Effective date of registration: 20170206 Address after: 330096 Jiangxi city of Nanchang province Wanli District Zhaoxian Road No. 1 River Valley Patentee after: JIANGXI JIANGZHONG DIETOTHERAPY TECHNOLOGY Co.,Ltd. Address before: 330096 Nanchang high tech Zone, Jiangxi Torch Road, No. 788 Patentee before: JIANGXI JIANGZHONG PHARMACEUTICAL (Group) Co.,Ltd. |
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Effective date of registration: 20210730 Address after: 188 Chaoyang Avenue, Gongqingcheng high tech Zone, Jiujiang City, Jiangxi Province Patentee after: Jiangzhong dietotherapy Technology Co.,Ltd. Address before: Jiangzhong Medicine Valley, No. 1 Zhaoxian Road, Wanli District, Nanchang City, Jiangxi Province Patentee before: JIANGXI JIANGZHONG DIETOTHERAPY TECHNOLOGY Co.,Ltd. |
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Denomination of invention: A health flour composition and food Effective date of registration: 20231127 Granted publication date: 20150304 Pledgee: Jiangxi Guofang Asset Operation Co.,Ltd. Pledgor: Jiangzhong dietotherapy Technology Co.,Ltd. Registration number: Y2023980067616 |